Clinical trials: Subjective Cognitive Impairment
Subjective Cognitive Decline (SCD), Subjective Cognitive Decline
Chinese Classics Recitation Training in Subjective Cognitive Decline
Subjective cognitive decline (SCD) is considered a preclinical condition associated with an increased risk of dementia and Alzheimer's disease.
- Trial name
- NCT07463391
- Testing
- Memory training by Chinese Classics recitation
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- China Medical University Hospital
Alzheimer Disease, Subjective Cognitive Decline
Neurofeedback Intervention for Preclinical Alzheimer's Disease
Alzheimer's disease (AD) is the most common form of neurodegenerative disorders leading to dementia. Currently, there has been no effective pharmacologic therapy for this disease.
- Conditions
- Alzheimer Disease, Subjective Cognitive Decline, Neurofeedback, Electroencephalogram
- Trial name
- NCT04300933
- Testing
- Electroencephalogram-based neurofeedback
- Where
- China
- Volunteers
- 50 people
- Sponsor
- XuanwuH 2
Cognitive Decline, Subjective Cognitive Impairment
Effect of a Multidomain Intervention Plus Turmeric on the Prevention of Cognitive Decline in People Over 55 Years of Age With Insulin Resistance.
Introduction: The Insulin resistance itself has been recognized as an independent risk factor for dementia development. Insulin plays an important role in the regulation of muscle function and the processes of learning and…
- Conditions
- Cognitive Decline, Subjective Cognitive Impairment, Insulin Resistance
- Trial name
- NCT07284316
- Testing
- Turmeric extract
- Where
- Mexico
- Volunteers
- 100 people
- Sponsor
- Instituto Mexicano del Seguro Social
Working Memory, Post-covid-19
Influence of Fampridine on Working Memory in Individuals With Post COVID-19 Condition With Subjective Cognitive Impairment
In genome-wide association studies we identified potassium channels to be genetically linked to performance and neural activity of working memory in healthy humans.
- Trial name
- FamC (NCT05274477)
- Testing
- Fampridine SR
- Where
- Switzerland
- Volunteers
- 8 people
- Sponsor
- Prof. Dominique de Quervain, MD
Subjective Cognitive Decline
Effects of Cognitive Strategy Training on Daily Function in People With Subjective Cognitive Decline
Subjective cognitive decline (SCD) is the transitional state between normal aging and mild cognitive impairment. SCD is defined as having self-perceived declines in any cognitive domain over time; having normal performance on…
- Trial name
- NCT04330404
- Testing
- Cognitive strategy training, group interactive game
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- National Cheng Kung University
Alzheimer Disease, Subjective Cognitive Decline
dTMS for Subjective Cognitive Decline
Deep transcranial magnetic stimulation (dTMS) is a brain stimulation technique that involves generating a brief magnetic field in a coil that is placed on the scalp.
- Trial name
- NCT06095063
- Testing
- Active Brainsway H7-Coil Deep TMS System, Cognitive Training
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Rotman Research Institute at Baycrest
Alzheimer Disease, Subjective Cognitive Decline
German Validation Study of the Subjective Cognitive Decline Questionnaire (SCD-Q)
The SCD-Q (Subjective Cognitive Decline-Questionnaire) is an established instrument to quantify self-perceived cognitive decline. Both self- and informant-rated versions of the SCD-Q are available.
- Trial name
- NCT06711952
- Testing
- Subjective Cognitive Decline-Questionnaire (SCD-Q), Cognitive Failure Questionnaire (CFQ), biomarkers
- Where
- Germany
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ludwig-Maximilians - University of Munich
Insomnia, Sleep
Artificial Intelligence (AI)-Assisted Sleep Intervention for Insomnia in Older Adults With Subjective Cognitive Decline
To assess the feasibility and acceptability of Artificial Intelligence (AI)-assisted sleep intervention on improving the insomnia of older adults with subjective cognitive decline.
- Trial name
- NCT07588035
- Testing
- Artificial Intelligence (AI)-assisted sleep intervention, Usual Care
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The Hong Kong Polytechnic University
Subjective Cognitive Decline (SCD)
Efficacy and Olfactory Network of Electro-acupuncture for Subjective Cognitive Decline
Subjective cognitive decline (SCD) is the early diagnosis and treatment window period of Alzheimer's disease (AD), and the identification of SCD individuals who will progress to AD (pSCD) is a research hotspot.
- Trial name
- NCT06758154
- Testing
- "TXJN" electro-acupuncture
- Where
- China
- Volunteers
- 92 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Subjective Cognitive Decline (SCD), Subjective Cognitive Impairment
Physiological Effect of Non-invasive Photobiomodulation on Cognition and Mood in Older Adults With Subjective Cognitive Impairment
Subjective cognitive impairment (SCI) is a non-clinical condition manifesting as a self-reported decline in cognitive function without objective clinical evidence, and is prevalent among older adults and strongly associated with…
- Trial name
- NCT07445945
- Testing
- Photobiomodulation
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Baycrest
Presbycusis, Tinnitus
Effects of Huperzine a on Presbycusis(Δ,kHz, DB,MMSE, AD)
To investigate the effects of huperzine A on tinnitus suppression, hearing and cognitive function protection in patients with presbycusis-related subjective tinnitus and cognitive impairment.
- Conditions
- Presbycusis, Tinnitus, Cognitive Impairment
- Trial name
- NCT03101722
- Testing
- BTHE and Huperzine A, BETH
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Zhijun Bao
Subjective Cognitive Decline
Clinical and Biological Effects of Citrus-phytochemicals in Subjective Cognitive Decline.
Subjective cognitive decline (SCD) is receiving increasing attention as a risk factor for incident dementia due to AD. SCD manifests prior to the onset of clinical impairment, and as such could serve as a potential target…
- Trial name
- NCT04744922
- Testing
- Extracts of citrus peels standardized in AUR and NAR (phytocomplex).
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- IRCCS Centro San Giovanni di Dio Fatebenefratelli
Alzheimer Disease, Mild Cognitive Impairment
Blood Tests for Alzheimer's Disease: Can Plasma Biomarkers Diagnose and Predict Disease Progression
BLAD is a prospective, monocentric, observational epidemiological study with an additional procedure (annual blood draw) evaluating the diagnostic and prognostic performance of plasma biomarkers for Alzheimer's disease (AD) in a…
- Conditions
- Alzheimer Disease, Mild Cognitive Impairment, Subjective Cognitive Decline, Dementia
- Trial name
- BLAD (NCT07717567)
- Testing
- Annual blood draw for plasma biomarker measurement
- Where
- Italy
- Volunteers
- 2,000 people
- Sponsor
- IRCCS San Raffaele
Cognitive Decline, Healthy Aging
Non-invasive Brain Stimulation and Strategic Memory Training
Physiological aging is often associated with memory function decline. Recently, the use of transcranial direct current stimulation (tDCS), a type of non-invasive brain stimulation, has been combined with adaptive working memory…
- Trial name
- StMe-tDCS (NCT05929872)
- Testing
- Non-invasive brain stimulation
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- IRCCS National Neurological Institute "C. Mondino" Foundation