Clinical trials: Stuttering
Developmental Stuttering
Dopamine Function in Developmental Stuttering
This study will use positron emission tomography (PET) to examine the role of the chemical messenger dopamine in stuttering. It will measure and compare the number of dopamine receptors and the amount of dopamine released in the…
- Trial name
- NCT00024960
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- National Institute on Deafness and Other Communication Disorders (NIDCD)
Stuttering, Fluency Disorders
Enhancing Speech Fluency With Non-invasive Brain Stimulation in Developmental Stuttering
This study aims to test whether the addition of transcranial direct current stimulation (TDCS) to speech fluency training results in improvements in speech fluency in adults with developmental stuttering.
- Conditions
- Stuttering, Fluency Disorders, Speech Disorders
- Trial name
- NCT02288598
- Testing
- Anodal TDCS, Fluency Training
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Oxford
Stuttering, Adult, Childhood-onset Fluency Disorder
Efficacy and Tolerability of Ecopipam in Adults With Childhood Onset Fluency Disorder (Stuttering).
The primary objective of this study is to evaluate the efficacy and tolerability of ecopipam in reducing stuttering symptoms. It is hypothesized that ecopipam effectively reduces stuttering symptoms as measured on the SSI-IV…
- Conditions
- Stuttering, Adult, Childhood-onset Fluency Disorder, Speech Disorders, Language Disorders
- Trial name
- NCT02909088
- Testing
- Ecopipam 50mg, Ecopipam 100mg
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Gerald Maguire, MD
Stammering
Pilot: Group Therapy for Children Who Stammer
The aim of the study is to answer the question: Is a large-scale research study of the effectiveness of group speech and language therapy (SALT) for young people who stammer possible? The study will look at the issues involved in…
- Trial name
- NCT00945113
- Testing
- One-week speech therapy group
- Where
- United Kingdom
- Volunteers
- 6 people
- Sponsor
- Newcastle-upon-Tyne Hospitals NHS Trust
Stuttering
A Randomized, Placebo-Controlled Study to Evaluate the Efficacy and Tolerability of Asenapine With Flexible Dosing From 5mg to 20mg in Adults With Developmental Stuttering
The purpose of this research study is to find out the potential benefits and safety of asenapine (Saphris®) in adults who suffer from the developmental form of stuttering.
- Trial name
- NCT01684657
- Testing
- Asenapine
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Stuttering
The Effects of Tactile Speech Feedback on Stuttering Frequency
The purpose of this research project is to test the effects of exposure of different forms of tactile speech feedback on overt stuttering frequency.
- Trial name
- NCT01315730
- Testing
- Tactile Stimulation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Mississippi, Oxford
Persistent Developmental Stuttering
EXPRESS: Examining Pagoclone for Persistent Developmental Stuttering Study
The objective of the study is to determine the effects of pagoclone on the symptoms of Persistent Developmental Stuttering, using a flexible dosing titration regimen on persistent developmental stuttering in patients 18 to 65…
- Trial name
- NCT00216255
- Testing
- Pagoclone
- Where
- 16 sites in United States
- Volunteers
- 120 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Stuttering
A Study to Assess the Efficacy and Safety of Pagoclone for Adults With Stuttering
A multicenter, randomized, 3 arm, placebo-controlled clinical trial to assess the efficacy, safety and tolerability of pagoclone for adults with stuttering.
- Trial name
- NCT00830154
- Testing
- pagoclone
- Where
- United States
- Volunteers
- 321 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Persistent Developmental Stuttering
Safety and Efficacy Study of the Investigational Drug Pagoclone, in the Treatment of Persistent Developmental Stuttering (PDS)
This is a research study of the investigational drug, Pagoclone, in the treatment of persistent developmental stuttering (PDS), which includes frequent repetitions or prolongations of sounds or syllables or words, or frequent…
- Trial name
- NCT00239915
- Testing
- Pagoclone
- Where
- United States
- Sponsor
- Pharmacology Research Institute
Stuttering
Follow-up of Children After Stuttering Treatment
This study aims to determine the percentage and predictors of stuttering relapse following treatment with the Lidcombe Program. It will also investigate the effectiveness of sending reminder messages to parents to assist in…
- Trial name
- NCT00709072
- Testing
- SMS (Short Message Service) reminders
- Where
- Australia
- Volunteers
- 180 people
- Sponsor
- University of Sydney
Stuttering, Developmental Apraxia of Speech
Stuttering and Apraxia of Speech: the Efficacy of an Intervention Program
Subjects' utterances were submitted to acoustic analysis before and after the intervention program applied on prosodic basis.
- Trial name
- SAS:EIP (NCT01097161)
- Testing
- speech therapy with the assistance of an acoustical analysis program
- Where
- Brazil
- Volunteers
- 4 people
- Sponsor
- Federal University of Minas Gerais
Stuttering
Spacing Lidcombe Program Clinic Visits
The purpose of this study is to evaluate the efficiency of the Lidcombe Program for early stuttering by varying the time between clinic visits during the first stage of the program.
- Trial name
- NCT00680303
- Testing
- The Lidcombe Program for early stuttering
- Where
- 2 sites in Australia, Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Sydney
Stuttering
Genetic Factors Related to Stuttering
Stuttering is an abnormality in speech that affects the rhythm of speech. People who stutter know what they wish to say, but at the time are unable to say it because of involuntary repetition, unnecessary lengthening…
- Trial name
- NCT00001602
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- National Institute on Deafness and Other Communication Disorders (NIDCD)
Stuttering
Activity of the Auditory Cortex During Speech Perception and Speech Production in Stuttering
The goal of the study is to examine the cortical activity during speech perception and speech production in idiopathic stutterers compared to fluent speakers.
- Trial name
- NCT00148161
- Where
- 2 sites in Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital Muenster