Clinical trials: Stuttering
Stuttering
Stuttering and Neuromodulation
The purpose of this study is to collect preliminary data on the efficacy of transcranial direct current stimulation (tDCS) combined with traditional behavioral techniques to reduce stuttering severity and negative impact in…
- Trial name
- NCT07222163
- Testing
- Soterix Medical 1x1 tDCS system, Speech therapy sessions
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- NYU Langone Health
Stuttering, Adult
Bihemispheric Transcranial Direct Current Stimulation* on Speech Fluency
It will be determined whether bihemispheric stimulation (anodal to the left IFG and cathodal to the right IFG) is used with fluency-facilitating conditions for 5 consecutive days in individuals with stuttering and whether there…
- Trial name
- TDCS (NCT06278233)
- Testing
- Transcranial direct current stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Biruni University
Stuttering, Developmental
TreatPaCS = Treatment for Preschool Age Children Who Stutter
Treatment for preschool age children who stutter: a randomised, multicentre, non-inferiority parallel group pragmatic trial with Mini-KIDS, the social cognitive behaviour therapy and the Lidcombe Program with 249 children
- Trial name
- TreatPaCS (NCT05185726)
- Testing
- Lidcombe Program, Mini-KIDS, Social Cognitive Behavioural Therapy
- Where
- Belgium
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Thomas More University of Applied Sciences
Stuttering
IBSR Intervention for Adults Who Stutter
Stuttering is a speech disorder that can cause disturbances in the timing and flow of speech. It is often accompanied not only by verbal difficulties but also by negative impact on several psycho-social aspects in the life of the…
- Trial name
- NCT04580966
- Testing
- Inquiry Based Stress Reduction (IBSR) workshop
- Where
- Israel
- Volunteers
- 56 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Stuttering, Developmental Apraxia of Speech
Stuttering and Apraxia of Speech: the Efficacy of an Intervention Program
Subjects' utterances were submitted to acoustic analysis before and after the intervention program applied on prosodic basis.
- Trial name
- SAS:EIP (NCT01097161)
- Testing
- speech therapy with the assistance of an acoustical analysis program
- Where
- Brazil
- Volunteers
- 4 people
- Sponsor
- Federal University of Minas Gerais
Stuttering
Spacing Lidcombe Program Clinic Visits
The purpose of this study is to evaluate the efficiency of the Lidcombe Program for early stuttering by varying the time between clinic visits during the first stage of the program.
- Trial name
- NCT00680303
- Testing
- The Lidcombe Program for early stuttering
- Where
- 2 sites in Australia, Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Sydney
Developmental Stuttering
Effectiveness of Digital Manipulation of Thyroid Cartilage and Fluency Shaping Therapy for the Management of Stuttering in Adult
This study was conducted to determine the effectiveness of digital manipulation of thyroid cartilage for the management of stuttering in adult.There were three groups,Group A received Digital Manipulation of Thyroid cartilage…
- Trial name
- NCT03628755
- Testing
- Digital Manipulation of Thyroid cartilage, Fluency Shaping Therapy, combination Group
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Isra University
Stammering
Modifying Unconscious Tongue Movements in Adults With Developmental Stammer.
This is a pilot randomised controlled trial investigating whether using modification of saccadic eye movements can control lateral unconscious tongue positioning and enhance fluency in adults with a confirmed developmental…
- Trial name
- NCT04310436
- Testing
- Modifying saccades by looking down to naval., Modifying saccades by looking in air.
- Where
- Ireland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Institute of Technology, Sligo
Stuttering
A Randomized, Placebo-Controlled Study to Evaluate the Efficacy and Tolerability of Asenapine With Flexible Dosing From 5mg to 20mg in Adults With Developmental Stuttering
The purpose of this research study is to find out the potential benefits and safety of asenapine (Saphris®) in adults who suffer from the developmental form of stuttering.
- Trial name
- NCT01684657
- Testing
- Asenapine
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Stuttering, Adult
Dopamine and Sensorimotor Function in Stuttering
This study is being done to understand the effect of aripiprazole on adults who stutter. Stuttering is a disorder that affects speech fluency.
- Trial name
- NCT07215884
- Testing
- Aripiprazole 10 MG
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Stuttering, Childhood
Correlation of Family History, Age at Onset & Severity of Stuttering
The aim of this study is to Detect the influence of the family history of stuttering (distance of relative) on the onset and severity of stuttering in children in these families.
- Trial name
- NCT04412213
- Testing
- Stuttering severity instrument for school-age children (SSI-3 Arabic version)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Stuttering, Adult, Stammering
Study of the Effect of the Auditory Stimulation on Stuttering Symptoms in Patients With a Deficit of Spectral Power in the EEG Beta Frequency Band
In this study, the investigators will research the efficacy of a novel auditory neuro modulating technology that leverages euphonic music tracks with broad-spectrum binaural beats to induce selective EEG spectral power changes.
- Trial name
- ZOV (NCT05339906)
- Testing
- ZOV.ai digital therapy candidate
- Where
- Ukraine
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Oles Honchar Dnipro National University
Stuttering, Adult, Childhood-onset Fluency Disorder
Efficacy and Tolerability of Ecopipam in Adults With Childhood Onset Fluency Disorder (Stuttering).
The primary objective of this study is to evaluate the efficacy and tolerability of ecopipam in reducing stuttering symptoms. It is hypothesized that ecopipam effectively reduces stuttering symptoms as measured on the SSI-IV…
- Conditions
- Stuttering, Adult, Childhood-onset Fluency Disorder, Speech Disorders, Language Disorders
- Trial name
- NCT02909088
- Testing
- Ecopipam 50mg, Ecopipam 100mg
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Gerald Maguire, MD
Persistent Developmental Stuttering
EXPRESS: Examining Pagoclone for Persistent Developmental Stuttering Study
The objective of the study is to determine the effects of pagoclone on the symptoms of Persistent Developmental Stuttering, using a flexible dosing titration regimen on persistent developmental stuttering in patients 18 to 65…
- Trial name
- NCT00216255
- Testing
- Pagoclone
- Where
- 16 sites in United States
- Volunteers
- 120 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Stuttering
Large Language Models for Stuttering Assessment and Therapy
This observational study aims to compare the quality of responses generated by four large language models (ChatGPT, Claude, Google Gemini, and Grok-4.20) to questions about stuttering.
- Trial name
- NCT07835347
- Testing
- ChatGPT-Generated Responses, Claude-Generated Responses, Google Gemini-Generated Responses
- Where
- Turkey (Türkiye)
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Istanbul Gelisim University
Stuttering, Down Syndrome
How Stuttering and Gestures Influence the Intelligibility of Individuals With Down Syndrome
This study wants to determine the relationship between spontaneous hand gestures, stuttering and intelligibility in individuals with Down syndrome. One third of these individuals has fluency problems, such as stuttering.
- Conditions
- Stuttering, Down Syndrome, Intelligibility, Speech, Gestures
- Trial name
- NCT03698539
- Testing
- hand gestures
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Stuttering
Effects of Psilocybin on Speech Fluency, Struggle, and Brain Activity in People Who Stutter
This Phase 2a clinical trial is an open-label, single-group, within-subjects pilot study designed to evaluate the safety, feasibility, and preliminary efficacy of psilocybin as a therapeutic intervention for adults with…
- Trial name
- NCT07296328
- Testing
- Psilocybin, Speech therapy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- NYU Langone Health
Developmental Stuttering, Evoked Potentials Auditory
Effect of Stuttering Remediation Exercises on Cortical Auditory Evoked Potentials
studying how the cortical auditory evoked potentials differ in children who stutter from who do not stutter and how these potentials change with therapy
- Trial name
- NCT05473572
- Testing
- Fluency shaping exercises
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Alaa Mamdouh
Stuttering, Adult
Using Transcranial Magnetic Stimulation to Treat Stuttering
The goal of this clinical trial is to learn if repeated transcranial magnetic stimuli (rTMS) can treat stuttering in adults. The main questions it aims to answer are: Will there be changes in the brains of people who stutter…
- Trial name
- NCT07389694
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Kansas State University
Stuttering, Adult
Effects of Altered Auditory Feedback on Speech Fluency
The purpose of the study is to use altered auditory vocal feedback to increase fluency in people who stutter and to examine changes in this effect over the course of a one month period occurring outside the laboratory setting.
- Trial name
- NCT06011837
- Testing
- Altered Auditory Feedback
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Massachusetts Institute of Technology