Clinical trials: Stroke Volume
Fluid Challenge, Hemodynamic Monitoring
Tidal Volume Challenge and Lung Recruitment Maneuver (TIDALREC): the Reliability of Pulse Pression Variation or Stroke Volume Variation on Fluid Responsiveness.
In order to predict fluid responsiveness in the operating room and therefore benefit of performing fluid administration to improve patient's hemodynamic status, it will test two ventilation strategies : the Tidal Volume Challenge…
- Trial name
- TIDALEC (NCT04535115)
- Testing
- Starting LRM (Lung Recruitment Maneuver), Starting VtC (Tidal Volume Challenge)
- Where
- France
- Volunteers
- 160 people
- Sponsor
- University Hospital, Lille
Acute Heart Failure (AHF)
Evaluating the Effects of Nitroglycerin on Heart Function and Urinary Output in Patients With Acute Heart Failure
This study aims to understand how nitroglycerin affects patients with acute heart failure, a condition where the heart struggles to pump blood effectively, leading to fluid buildup and breathing difficulties.
- Trial name
- NCT06682260
- Testing
- Nitroglycerin (NTG)
- Where
- Denmark
- Volunteers
- 21 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Brain Tumor
Effect of Goal-directed Fluid Therapy Based on Stroke Volume Variation on Metabolic Acidosis in Patients Undergoing Brain Tumor Surgery
In patients undergoing craniotomy, 0.9% normal saline is commonly administered in order to reduce cerebral edema. Excessive administration of 0.9% normal saline has been to reported to cause hyperchloremic metabolic acidosis.
- Trial name
- NCT01738880
- Testing
- SVV, CVP
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Yonsei University
Supratentorial Neoplasms, Brain Tumor, Primary
Comparison of Stroke Volume Variation-guided Normovolemic and Restrictive Fluid Management During Craniotomy: a Randomized Controlled Trial
Fluid management during neurosurgery presents a special clinical agenda. Volume overload can have detrimental effects on intracranial pressure by increasing either cerebral blood volume or hydrostatically driven cerebral edema…
- Conditions
- Supratentorial Neoplasms, Brain Tumor, Primary, Craniotomy
- Trial name
- NCT02113358
- Testing
- Intravenous colloid bolus with Voluven
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- National Taiwan University Hospital
Liver Transplantation
Validation of Cardiometry in Resuscitation of Patients Undergoing Liver Transplantation
aim of our study to validate electrical cardiometry readings against same readings by transoesophageal echo. we will validate stroke volume (SV) readings stroke volume variation(SVV), index of contractility.
- Trial name
- NCT03228329
- Testing
- fluid boluses
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Kasr El Aini Hospital
Fluid Overload, Fluid Loss
Atrial Natriuretic Peptide in Assessing Fluid Status
Biomarkers can play a significant role in fluid status assessment intraoperatively.
- Conditions
- Fluid Overload, Fluid Loss, Volume Overload, Cardiac Disease
- Trial name
- NCT05070819
- Testing
- pro-ANP
- Where
- Russia
- Volunteers
- 30 people
- Sponsor
- Petrovsky National Research Centre of Surgery
Hemodynamic, Monitoring, Anesthesia
Pulse CONtour and BIoimpedance for Measurements of Stroke Volume During Changes in CARdiac Preload
Fluid therapy guided by stroke volume response to repeated fluid challenges is used for hemodynamic optimization during general anesthesia.
- Conditions
- Hemodynamic, Monitoring, Anesthesia, Blood Pressure
- Trial name
- ConBi-Car (NCT04231656)
- Testing
- CLEARSIGHT and NICCOMO measurements in sequence A, CLEARSIGHT and NICCOMO measurements in sequence B
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Lille
Comparison of Availability for Prediction of Volume Responsiveness, Comparison of Limits of Agreement for Invasive and Non-invasive Measurement of Stroke Volume Variation
Non-invasive Measurement of Central Hemodynamics by Electrical Impedance Tomography
The purpose of this study is to evaluate the ability to measure central hemodynamics and heart-lung interactions non-invasively by electrical impedance tomography and compare it to clinically established hemodynamic monitoring.
- Trial name
- NCT01412970
- Testing
- volume loading
- Where
- Germany
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Sepsis, Shock, Septic
Emergency Department Management of Sepsis Patients: A Goal-Oriented Non-Invasive Sepsis Trial
The purpose of this study is to determine whether the use of a 3-hour protocol utilizing non-invasive hemodynamic optimization treatment strategy results in better outcome and lower hospital costs in patients who present with…
- Trial name
- AGONIST (NCT01453270)
- Testing
- NICOM, Usual care
- Where
- Singapore
- Volunteers
- 122 people
- Sponsor
- National University Hospital, Singapore
POTS
POTS Stroke Volume
the investigators propose studies of a tiny, wearable, wireless, beat-to-beat blood pressure monitor that will be both a transformative research platform and an enabler of patient self-care in the diagnosis, investigation, and…
- Trial name
- NCT05796154
- Testing
- ear blood pressure monitor
- Volunteers
- 30 people
- Sponsor
- University of Calgary
Heart Failure
Necklace-Shaped Sensor for Non-Invasive Monitoring of Stroke Volume and Cardiac Output
Study will compare measurements made with Necklace device for stroke volume/cardiac output with values from a FDA-approved reference device. The gold standard that will be used is Cardiac MRI.
- Trial name
- NCT02719301
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Baxter Healthcare Corporation
Coronary Artery Disease
Dynamic Arterial Elastance for Prediction of Vasopressor Requirement After Anesthesia Induction in Elective On-Pump CABG
This study aims to determine whether dynamic arterial elastance (EaDyn), measured after anesthesia induction, can predict the need for vasopressor treatment in patients undergoing elective on-pump coronary artery bypass graft…
- Trial name
- NCT07871201
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Elzem SEN
Heart Failure
Validation of Electrical Cardiometry Versus Fick Method in Cardiac Output Measurement
The investigators would like to find out if AESCULON®, a new device that non-invasively and continuously measures cardiac output using electrical cardiometry, works as well as one existing method--Fick method in patients…
- Trial name
- NCT01568619
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Massachusetts General Hospital
Bladder Cancer, Radical Cystectomy
The Effect of Goal-directed Hemodynamic Therapy in Radical Cystectomy
Goal-directed therapy (GDT) has been applied to various clinical settings and has been widely researched recently as a method for perioperative management of patients.
- Trial name
- NCT03505112
- Testing
- Goal-directed therapy
- Where
- South Korea
- Volunteers
- 82 people
- Sponsor
- Seoul National University Hospital
Coronary Artery Bypass Grafting, Fluid Therapy
Comparison of Dynamic Fluid Responsiveness by EIT and Transpulmonary Thermodilution in Postoperative of CABG Patients
The purpose of this study is to evaluate the stroke volume variation measured by both methods: transpulmonary thermodilution and electrical impedance tomography (EIT), during fluid responsiveness maneuvers and after fluid…
- Conditions
- Coronary Artery Bypass Grafting, Fluid Therapy, Stroke Volume, Hemodynamic Monitoring
- Trial name
- NCT04362033
- Testing
- Passive Leg Raising (PLR) and PEEP increment (PEEP)
- Where
- Brazil
- Volunteers
- 28 people
- Sponsor
- Ludhmila Abrahão Hajjar
Hemodynamic Instability
Effect of Extended Infusion Lines on Pulse Contour-based Measurements
Hemodynamic monitoring of the critically-ill patients is increasingly performed using an arterial pulse contour-based cardiac output device such as the proAQT system.
- Trial name
- NCT03599440
- Testing
- Pressure line extensions
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Hemodynamic Instability
Patient Management During Major Abdominal Surgery: an Oxygen Consumption Protocol Compared to Standard Approach
This study compares the actual standard of care with a new protocol to guide hemodynamic optimization during major abdominal surgery, which is more tailored on patient real needs.
- Trial name
- HEART-CORE (NCT03113435)
- Testing
- Oxygen consumption optimization
- Where
- Italy
- Volunteers
- 76 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Surgical Procedure, Unspecified
Non-invasive Assessment of Arterial Blood Pressure and Functional Hemodynamic Parameters
Cardiac output can be monitored using different invasive devices. Nexfin HD is a new, noninvasive device that uses model flow technology to measure stroke volume and thus computes cardiac output (CO).
- Trial name
- NCT01292759
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- Johannes Gutenberg University Mainz
Surgery, Cardiac Output, Low
Reliability of a New Pulse Contour Technique for Diagnosing an Increase in Stroke Volume During a Fluid Challenge for Hemodynamic Optimization in Patients Scheduled for High-risk Abdominal Surgery: Comparison With Transthoracic Echocardiography: COMPARE Study
The present study aims at assessing the ability of a new pulse contour device for diagnosing a >15% stroke volume (SV) increase during patient hemodynamic optimization by fluid challenge in high risk abdominal surgery.
- Trial name
- COMPARE (NCT04871620)
- Testing
- >15% SV increase during fluid challenge
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Monitoring, Physiological
Perfusion Index in Anesthesia
In patients under general anesthesia the investigators wish to investigate association and covariance between a peripheral perfusion index as obtained by Radical 7 monitor (Masimo, Irvine, CA, USA) and more traditional…
- Trial name
- NCT02989441
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Jakob Højlund