Clinical trials: Stroke
Stroke, Chronic, Aging
AMPLIFI: Adaptive Modulation of Plasticity Through Lactate and Fitness Interventions
The AMPLIFI study (Adaptive Modulation of Plasticity through Lactate and Fitness Interventions) investigates how short-term aerobic exercise influences brain plasticity and learning in older adults and stroke survivors.
- Conditions
- Stroke, Chronic, Aging, Cognitive Decline, Motor Dysfunction
- Trial name
- AMPLIFI (NCT06950060)
- Testing
- High intensity cycling, Low-intensity cycling, Health education session
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Cardiovascular Diseases, Acute MI
Impact of the Genetic Background as a Risk Factor for Atherosclerotic Cardiovascular Disease in the Brazilian Population
The main objective of this project is to evaluate the genomic information previously associated with cardiovascular diseases (CVD) and its importance as an independent risk predictor (expressed in Odds Ratio) when adjusted for…
- Conditions
- Cardiovascular Diseases, Acute MI, Stroke, Peripheral Arterial Disease
- Trial name
- CV-GENES (NCT05515653)
- Testing
- Exposure to genetics (polygenic)
- Where
- 41 sites in Brazil
- Volunteers
- 3,974 people, healthy volunteers welcome
- Sponsor
- Hospital Alemão Oswaldo Cruz
Heat Stroke
Study of Thermoregulation in Exercise Heat Stroke in the Military Environment
The EXPLO-MITO study is an ancillary study from the main EXPLO-CCE study (NCT04593316; IDRCB: 2020-A01967-32). The Heat Tolerance Test (HTT) is a physiological exploration that has several advantages for use in research and…
- Trial name
- EXPLO-MITO (NCT05847465)
- Testing
- Bike stress test, Heat Tolerance Test, Heat nociception test
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Stroke, Incentives
Stroke Patients' Outpatient Rehabilitation Therapy (SPORT)
Background: Stroke is the leading cause of long-term disability in Singapore, and studies have found that intensive specialized stroke rehabilitation can improve post-stroke functional outcomes for a substantial proportion of…
- Conditions
- Stroke, Incentives, Stroke Rehabilitation
- Trial name
- SPORT (NCT03165630)
- Testing
- Transportation incentives, Transportation and rehabilitation services incentives
- Where
- Singapore
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Hyperthermia
Rapid Cool: Heat Stroke Treatment
Hot climates such as in Phoenix, AZ commonly have individuals experiencing heat stroke, a life-threatening medical emergency. The dangerously high body temperature can result in death if not treated immediately with rapid body…
- Trial name
- NCT07743619
- Testing
- Recirculated water, Phoenix protocol
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Cerebrovascular Accident, Healthy
Interhemispheric Interactions Associated With Performance of Voluntary Movements in Patients With Stroke Motor Disability
This study will use transcranial magnetic stimulation (TMS) to identify interactions between the unaffected and affected side of the brain in stroke patients.
- Trial name
- NCT00029718
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Stroke, Cognitive Disorders
Post-stroke Cognitive Impairment and Dementia
Projections from epidemiological studies suggest that, among the Western adult population, one in three will present a cerebrovascular accident (stroke), severe cognitive disorders, or both.
- Conditions
- Stroke, Cognitive Disorders, Behavioral Disorders
- Trial name
- GRECogVASC (NCT01339195)
- Testing
- French adaptation of NINDS-Canadian Stroke Network battery
- Where
- 7 sites in France
- Volunteers
- 1,635 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Vision Loss Partial, Vision; Loss, Both Eyes
Effect of Visual Retraining After Stroke
This project is intended to collect data using standard clinical tests and psychophysics to quantify the effect of visual cortical damage on the structure of the residual visual system, visual perception, spatial awareness, and…
- Conditions
- Vision Loss Partial, Vision; Loss, Both Eyes, Hemianopia Homonymous, Hemianopia
- Trial name
- urochester (NCT06121219)
- Testing
- Training in the Blind Field
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Motor Activity
Variability of Healthy People and People After Stroke Results in the Box and Block Test
Main aim of the study is to find out how many attempts of each subtest in the Box and Block Test should be done in clinical practice during testing people after stroke who are 20-64 years old.
- Trial name
- NCT05925231
- Testing
- Box and Block Test
- Where
- 2 sites in Czechia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Type 2 Diabetes, Stroke
The Effect of GLP-1 on Glucose Uptake in the Brain and Heart in Healthy Men
Type 2 diabetes mellitus, T2D is a disease characterized by an immense growing prevalence world wide with an increased risk of myocardial infarction and stroke.
- Conditions
- Type 2 Diabetes, Stroke, Myocardial Infarction
- Trial name
- NCT00256256
- Testing
- glucagon-like-peptide-1
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Acquired Brain Injury Including Stroke, Epilepsy
Cognitive Rehabilitation Using Neurofeedback With Brain-computer Interface
The goal of this clinical trial is to determine whether a Brain-Computer Interface Neurofeedback Training (BCI-NFT) programme can improve cognitive outcomes, and whether electroencephalography (EEG)-based measures can serve as…
- Trial name
- NCT07828496
- Testing
- Brain-computer interface with neurofeedback with 3D game sessions
- Where
- Singapore
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Stroke, Ischemic
Evaluation and Prediction of the Effect of EECP on HR-NICE Patients
Stroke is one of the most threatening causes of mortality and disability worldwide. High risk non-disabling ischemic cerebrovascular events (HR-NICE), defined by mild stroke complicating with greater than 50% atherosclerotic…
- Trial name
- NCT05718622
- Testing
- real EECP
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Death, Carotid Artery Disease
NOR-SYS: The Norwegian Stroke in the Young Study
NOR-SYS is a clinical research program about young ischemic stroke patients from 15 to 60 years. Patients, partners and the couple´s adult children who are at least 18 years old, are all invited to ultrasound examinations due to…
- Conditions
- Death, Carotid Artery Disease, Cardiovascular Disease, Peripheral Artery Disease
- Trial name
- NOR-SYS (NCT01597453)
- Testing
- Lifestyle counseling
- Where
- Norway
- Volunteers
- 1,062 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Aphasia
Based on the Spatio-temporal Coding Characteristics of Frontotemporal Network, This Paper Explores the Mechanism of Five-tone Speech Training in Reshaping Language Fluency Function.
To explore the mechanism of five-tone speech training in reshaping language fluency function and the clinical efficacy of aphasia language function, daily communication ability and communication efficiency based on the temporal…
- Trial name
- NCT07329751
- Testing
- Traditional Chinese Medicine Five-Tone Therapy, Melodic Intonation Training, Standard speech therapy; Routine medical treatment; Health education
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Fujian University of Traditional Chinese Medicine
Brain Injuries, Stroke
Novel Head Protection Prototype Device for Decompression Craniectomy
A proof-of-concept (POC) proposal to study the feasibility of customized head protection prototype device (HPPD) using 3D printed externally-applied moulded skin prosthesis integrated to the craniectomy bony skull defect.
- Trial name
- HPPD (NCT04021095)
- Testing
- Head protection prototype device
- Where
- Singapore
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Tan Tock Seng Hospital
Stroke
The Effect of rPMS on Motor Skill Performance in Persons With a Stroke.
In the past two decades, even as stroke cases increase around the world, advances in motor rehabilitation have been limited. Clinical trials of stroke rehabilitation have examined the therapeutic utility of several…
- Trial name
- NCT05833490
- Testing
- Repetitive Peripheral Magnetic Stimulation (rPMS)
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Heart Attack, Stroke
CV Wizard: Does a Clinical Decision Support Tool Improve CVD Risk Factor Control in Safety Net Clinics?
This project aims to reduce disparities in cardiovascular disease (CVD) risk factor control and in rates of heart attacks and strokes among the low-income, racially / ethnically diverse Americans who receive primary care at…
- Conditions
- Heart Attack, Stroke, Cardiovascular Diseases
- Trial name
- CV_WIZARD (NCT03001713)
- Testing
- CV WIZARD
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Stroke, Oral Disease
Oral Health and Vitamin D in Stroke Patients
Stroke is a common, serious and restrictive global health problem. Restricting the activities of daily living of stroke patients impairs patients' ability to pay attention to oral hygiene.
- Conditions
- Stroke, Oral Disease, D Vitamin Deficiency
- Trial name
- NCT05418335
- Testing
- Clinical examination, functional status evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Stroke, Hypertension
Family at Risk Study
Atherosclerotic cardiovascular disease (ASCVD) risk factors include hypertension as a key risk factor, as well as hyperlipidemia, diabetes, smoking, obesity, diet, inactivity, family history and age.
- Trial name
- FAR (NCT04607876)
- Testing
- Technological Facilitator, Standard of Care
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Stroke, Hemiplegia
Clinical Application of Portable Intelligent Multi Joint Isokinetic Training and Evaluation System Technology
The goal of this clinical trial is to compare in describeparticipant population. The main question it aims to answer is:By using intelligent portable isokinetic tester and traditional isokinetic tester, isokinetic knee flexor and…
- Conditions
- Stroke, Hemiplegia, Rehabilitation; Tobacco Use, Physical Disability
- Trial name
- NCT06153992
- Testing
- Intelligent portable isokinetic muscle strength test training, isokinetic muscle strength test training, without test training
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ran Shi
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