Clinical trials: Step
Medication Nonadherence, Depression
The Effectiveness of CBI on Depression and Adherence in HIV Infected Adolescents
Aim: To explore the effectiveness of psychoeducation and problem-solving (Life-steps) on depression and adherence in HIV-infected adolescents.
- Conditions
- Medication Nonadherence, Depression, HIV Infections
- Trial name
- NCT05482217
- Testing
- Psychoeducation, problem solving and rehearsal (cognitive behavioural intervention)
- Where
- Botswana
- Volunteers
- 25 people
- Sponsor
- University of Botswana
Cystic Fibrosis
Steps Ahead: Optimising Physical Activity and Health in Adults With Cystic Fibrosis
Physical activity is widely documented as one of the cornerstones of Cystic Fibrosis (CF) management as it is directly linked to mortality and quality of life.
- Trial name
- NCT03672058
- Testing
- Fitness tracker with goal setting and text message feedback, Fitness Tracker only
- Where
- Ireland
- Volunteers
- 60 people
- Sponsor
- University of Limerick
Sepsis, Low Blood Pressure
MID-STEP (MIDodrine for Sepsis Treatment and Early vasoPressor Weaning) Trial
This study is being done to determine if early administration of Midodrine can improve outcomes by maintaining a higher mean blood pressure off of intravenous medications.
- Trial name
- NCT06319248
- Testing
- Midodrine, Standard of Care
- Where
- 5 sites in United States
- Volunteers
- 308 people
- Sponsor
- Mayo Clinic
Osteoarthritis, Knee Osteoarthritis
Transplantation of Bone Marrow Stem Cells Stimulated by Proteins Scaffold to Heal Defects Articular Cartilage of the Knee
The purpose of this pilot study is to investigate the efficacy and safety of autologous transplantation, under arthroscopy, of Bone Marrow Mesenchymal stem cells, using, with a cell separator, a fresh non-culture expanded…
- Conditions
- Osteoarthritis, Knee Osteoarthritis, Osteochondritis Dissecans, Osteonecrosis
- Trial name
- NCT01159899
- Testing
- Transplantation of Bone Marrow Stem Cells Activated in Knee Arthrosis
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Michel Assor, MD
Progesterone Resistance
Step Down FSH Approach and Late Follicular Phase in Progesterone Level
Step-down approach and late follicular phase progesterone level
- Trial name
- FSH (NCT03356964)
- Testing
- follicle stimulating hormone
- Where
- United Arab Emirates
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Psychosis;Schizophrenic
Seven-step Phenomenological Psychotherapy for Self-disorder - a Pilot Study
The goal of this clinical pilot study is to learn how adults with schizophrenia or other non-affective psychotic disorders or psychosis risk syndromes experience a novel psychotherapeutic treatment for self-disorders.
- Trial name
- SSPP-SD-p (NCT06597864)
- Testing
- Seven-step phenomenological psychotherapy for self-disorders
- Where
- 2 sites in Norway
- Volunteers
- 8 people
- Sponsor
- Oslo University Hospital
Sedentary Behavior, Aging
Oral 'Breath Test' to Measure Anabolic Sensitivity in Young and Older Adults at Different Activity Levels
Recent work in the investigators laboratory has examined the ability of a non-invasive 13CO2 breath-test to assess differences in amino acid oxidation rates and net balance in young healthy males following protein feeding and…
- Conditions
- Sedentary Behavior, Aging, Sarcopenia, Amino Acids
- Trial name
- ARBT (NCT05216809)
- Testing
- Habitual Physical Activity, Step-Reduction
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Squamous Cell Carcinoma of the Oropharynx
Evaluation of Tongue Base MucOsectomy & Step sErial Sectioning
Squamous cell carcinoma (SCC) is a cancer that originates from the cells lining the body and can spread into the lymph glands and beyond. Some patients first present with an SCC which has moved to the lymph glands of the neck.
- Trial name
- MOSES (NCT04151134)
- Testing
- Step serial sectioning histological processing
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Chronic Kidney Disease (CKD) Stage 5, Kidney Dysfunction Requiring Dialysis (KDRD)
Incremental Hemodialysis for Veterans in the First Year of Dialysis (IncHVets)
In this pragmatic clinical trial, which will dovetail with Veterans' routine outpatient dialysis clinic visits in six VA medical centers, the investigators will study 252 Veterans with kidney disease who need to start dialysis…
- Conditions
- Chronic Kidney Disease (CKD) Stage 5, Kidney Dysfunction Requiring Dialysis (KDRD), Dialysis Dependency
- Trial name
- INCHVETS (NCT05465044)
- Testing
- Twice-weekly hemodialysis with incremental crossover to thrice-weekly schedule, Thrice-Weekly Hemodialysis
- Where
- 8 sites in United States
- Volunteers
- 252 people
- Sponsor
- VA Office of Research and Development
Hypercholesterolemia
Canadians Achieve Cholesterol Targets Fast With Atorvastatin Stratified Titration
The objective of this study is to assess the effectiveness of an atorvastatin treatment regimen involving starting doses between 10 and 80 mg, followed by a single-step titration (except for subjects started at 80mg), if required
- Trial name
- CANACTFAST (NCT00150371)
- Testing
- atorvastatin
- Where
- 84 sites in Canada
- Volunteers
- 1,100 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Physical Activity
Be Fit in Residency: a Randomized Controlled Trial of an Activity Device Among Medicine Residents
The main objective of this study is to test an intervention to increase the physical activity of medical residents, an employee population with little time for exercise. Specifically, the aims of this study are: 1.
- Trial name
- NCT01287208
- Testing
- Activity monitor, Activity device
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
AIMAS, Developmental Coordination Disorder
Smart Steps to Growth: Unleashing AI for Assessing Motor Skills in School Children
The purpose of this study is to develop an AI-based automated motor function assessment system (AIMAS) to improve early identification of developmental coordination disorder (DCD) in school-age children.
- Trial name
- NCT07083726
- Where
- Taiwan
- Volunteers
- 250 people
- Sponsor
- Chang Gung Memorial Hospital
Physical Activity
Active Over 45: A Step-up Jogging Program in Inactive Female Hospital Staff Aged 45+
Background: Inactive individuals face motivational obstacles for becoming and staying physically active. Therefore, sustainable physical activity promotion programs tailored to reach inactive individuals are needed.
- Trial name
- NCT01531660
- Testing
- step-up jogging program
- Where
- Switzerland
- Volunteers
- 68 people
- Sponsor
- University of Zurich
Renal Failure
Buttonhole Versus Step Ladder Cannulation in High Dose Hemodialysis
The purpose of the pilot study is to determine: 1) Will patients agree to be randomized to two different methods of putting needles in their arteriovenous fistula and, 2) if we can adequately coordinate all of the sites to get…
- Trial name
- NCT01962025
- Testing
- Buttonhole needling technique
- Where
- 3 sites in Canada
- Volunteers
- 14 people
- Sponsor
- Ottawa Hospital Research Institute
Bone Metastases
Double-bed SPECT/CT for Bone Scintigraphy in Initial Staging of Cancer Patients
Bone scintigraphy is currently a reference test in the initial staging of cancer. Bone scintigraphy historically consists in a planar whole-body scintigraphy (WBS).
- Trial name
- DTOM (NCT03353090)
- Where
- France
- Volunteers
- 102 people
- Sponsor
- University Hospital, Brest
Induction of Labor
Foley Bulb With Low Dose Pitocin Versus Foley Bulb With a Standard Incremental Infusion Protocol for the Induction of Labor
The purpose of this research study is to compare induction of labor using a foley catheter bulb with a low dose of oxytocin versus a foley catheter bulb with an increasing dose of oxytocin.
- Trial name
- NCT02150954
- Testing
- pitocin
- Volunteers
- 121 people
- Sponsor
- Duke University
Obesity, Childhood, Metabolic Syndrome
FIT Families Multicomponent Obesity Intervention for African American Adolescents
Obesity is one of the most prevalent medical problems facing children and adolescents today, particularly among African American adolescents where the rate is alarmingly high.
- Trial name
- NCT04974554
- Testing
- FIT, Home-Based Family Support
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- Medical University of South Carolina
Periodontal Inflammation
The Periodontal Status and Failure Rates With Different Retainer Bonding Techniques Using One-step Adhesive
The aim of this study was to evaluate fixed retainers, bonded with either direct or indirect techniques using one- or two-step adhesives, in terms of periodontal status and failure rates.
- Trial name
- NCT05458583
- Testing
- Baseline periodontal measurements (T0), Periodontal measurements (T1), Periodontal measurements (T2)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Cardiovascular Risk Factor
Pharmacist Enhanced Service for Cardiovascular Risk Reduction
Pharmacist services such as medication review, counselling and treatment adherence clinics can improve clinical, health related quality of life and economic outcomes.
- Trial name
- NCT04220788
- Testing
- Enhanced pharmacist service, Usual care
- Where
- Malaysia
- Sponsor
- Monash University
Lumbopelvic Pain
Effects of Two Different Kinesio Taping Applications on Pain and Functional Mobility in Pregnants With Lumbopelvic Pain
This study evaluates and compares the effects of two different kinesio taping applications on pain and functional mobility in pregnancy related lumbopelvic pain.
- Trial name
- NCT04139603
- Testing
- Lumbopelvic kinesio taping, Abdominal supported lumbopelvic kinesio taping
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Muğla Sıtkı Koçman University