Clinical trials: Standard Care Control
Ischemic Stroke, Acute Stroke
Aerobic Exercise Training in Acute Ischaemic Stroke
Stroke is a leading cause of adult disability in the UK. There are few treatment options that improve long-term disability outcomes after stroke.
- Conditions
- Ischemic Stroke, Acute Stroke, Cerebrovascular Accident
- Trial name
- ATAS (NCT04742686)
- Testing
- Aerobic exercise training
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Sheffield Hallam University
Internal Medicine, Surgery
Evaluation of A-DIVA Score Effectiveness at Admission for Preserving Venous Capital in Patients With Difficult Access
In certain cases (e.g.: patient who are difficult to perfuse, thin veins, etc.), an increase in venipunctures performed by study nurses in healthcare services can lead to a loss of venous capital, repeated pain during punctures…
- Conditions
- Internal Medicine, Surgery, Neurology
- Trial name
- ERV-ADIVA (NCT06952829)
- Testing
- evaluation of intravenous access of patients with Adult-Difficult IntraVenous Access (A-DIVA) score prior to puncturing subject, evaluation of intravenous access of patients with modified Adult-Difficult IntraVenous access(A-DIVA modified) score prior to puncturing subject
- Where
- France
- Volunteers
- 600 people
- Sponsor
- Centre Hospitalier Intercommunal Robert Ballanger
Systemic Lupus Erythematosus
The WILLOW Study With M5049 in SLE and CLE (SCLE and/or DLE) (WILLOW)
The purpose of this Proof of Concept (PoC) and Dose-finding (DF) basket study is to evaluate the efficacy and safety of orally administered Enpatoran over 24 weeks in systemic lupus erythematosus (SLE) and cutaneous lupus…
- Trial name
- NCT05162586
- Testing
- Enpatoran low dose, Enpatoran medium dose, Enpatoran high dose
- Where
- 153 sites in United States, Argentina and 20 more
- Volunteers
- 456 people
- Sponsor
- EMD Serono Research & Development Institute, Inc.
Leg Ulcer
Use of dHACM in the Treatment of Venous Leg Ulcers
The overall objective of this study is to evaluate the effectiveness of dehydrated human amnion/ chorion membrane (dHACM) in reducing time to complete wound closure in patients with venous leg ulcers (VLUs).
- Trial name
- NCT02011503
- Testing
- Multi-layer compression therapy, Application of dHACM
- Where
- 15 sites in United States
- Volunteers
- 128 people
- Sponsor
- MiMedx Group, Inc.
Intra-Abdominal Infections
Procalcitonin Guided Antibiotic Therapy
The overuse of antibiotics is an enormous problem facing the healthcare system both in the United States and across the world. The investigators plan to test the hypothesis that using procalcitonin levels (blood test) to guide…
- Trial name
- NCT04240288
- Testing
- Procalcitonin-guided antibiotic treatment, Standard of Care Antibiotic Treatment
- Sponsor
- Columbia University
Wound Complication
Closed Incision Negative Pressure Therapy vs Standard of Care
High risk patients who receive direct anterior approach total hip arthroplasty are more likely to experience wound complications.
- Trial name
- Prevena (NCT03061903)
- Testing
- Prevena, Aquacel
- Where
- 3 sites in United States, Canada
- Volunteers
- 122 people
- Sponsor
- Columbia University
Covid19
Fluvoxamine Administration in Moderate SARS-CoV-2 (COVID-19) Infected Patients
This is a randomized, double-blind, placebo-controlled, adaptive two-stage design, human phase 2 study, with add-on treatment arrangement of fluvoxamine or placebo on top of standard of care (base therapy: the actual proposed…
- Trial name
- NCT04718480
- Testing
- Fluvoxamine
- Where
- 4 sites in Hungary
- Volunteers
- 66 people
- Sponsor
- SigmaDrugs Research Ltd.
Diabetes Mellitus, Type 2, Obesity
Endoscopic Sutured Gastroplasty with Endomina® Device Versus Standard of Care in Patients with Type 2 Diabetes and Class I Obesity: a Multi-center, Randomized Controlled Trial
The primary objective of this study is to assess the efficacy of endoscopic gastric reduction with the endomina® device, in combination with standard of care, compared to standard of care alone, on the remission of diabetes 24…
- Trial name
- ESTIME (NCT05516576)
- Testing
- endomina®
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Grenoble
Partial Thickness Burn
Evaluation of Safety and Efficacy of Dehydrated Human Amnion-Intermediate-Chorion Membrane (dHAICM) Allograft in Treatment of Partial Thickness Thermal Burns
This study will evaluate the efficacy of a dehydrated human placental tissue product, commercially labeled as AmCoreMatrix Burn ™ versus SOC in the closure of partial thickness burns.
- Trial name
- PHOENIX (NCT07489560)
- Testing
- Amnion-Intermediate-Chorion, Standard of Care (SOC)
- Sponsor
- Cellution Biologics