Clinical trials: Stage III Childhood Hepatocellular Carcinoma

Adult Cholangiocarcinoma, Advanced Adult Hepatocellular Carcinoma

Trametinib or Combination Chemotherapy in Treating Patients With Refractory or Advanced Biliary or Gallbladder Cancer or That Cannot Be Removed by Surgery

• Completed
• Age: All ages
• Phase 2
• Injection or infusion
• Results posted

This randomized phase II trial studies how well trametinib or combination chemotherapy works in treating patients with refractory or advanced biliary or gallbladder cancer or that cannot be removed by surgery.

Conditions

Adult Cholangiocarcinoma, Advanced Adult Hepatocellular Carcinoma, BCLC Stage C Adult Hepatocellular Carcinoma, BCLC Stage D Adult Hepatocellular Carcinoma

Trial name

S1310 (NCT02042443)

Testing

Capecitabine, Fluorouracil, Laboratory Biomarker Analysis

Where

295 sites in United States

Volunteers

53 people

Sponsor

National Cancer Institute (NCI)