Clinical trials: Sprain
Carpal Tunnel Syndrome
Safety and Efficacy of Carpal Stim in Treating Carpal Tunnel Syndrome
The objective of this study is to assess the efficacy and safety of Carpal Stim for pain relief in CTS subjects.
- Trial name
- NCT05497037
- Testing
- PRF stimulation
- Where
- 5 sites in Taiwan
- Volunteers
- 58 people
- Sponsor
- GiMer Medical
Pain, Sprains and Strains
A Multi-Center, Randomized, Double-Blind, Parallel Group Study To Compare The Efficacy And Tolerability Of Valdecoxib And Diclofenac In Patients With A Sprained Ankle
To determine whether valdecoxib 40 mg twice a day the first day and then 40mg once a day until Day 7, was at least as effective as diclofenac 75 mg twice a day for 7 days, in treating acute first or second degree ankle sprain.
- Conditions
- Pain, Sprains and Strains, Sprain
- Trial name
- NCT00671320
- Testing
- valdecoxib, diclofenac
- Where
- 15 sites in Argentina, Chile and 3 more
- Volunteers
- 202 people
- Sponsor
- Pfizer
Sprain, Strain
Ketoprofen 10% Cream for Treatment of Pain Associated With Mild to Moderate Acute Soft Tissue Injury
Imprimis Pharmaceuticals is investigating a proprietary, topical cream formulation consisting of 10% ketoprofen (containing 100 mg of ketoprofen in 1gram of cream) for the local treatment of acute musculoskeletal pain.
- Conditions
- Sprain, Strain, Acute Soft Tissue Injury
- Trial name
- NCT00765700
- Testing
- Topical Ketoprofen 10% Cream
- Where
- United States
- Volunteers
- 364 people
- Sponsor
- Imprimis Pharmaceuticals, Inc.
Ankle Sprain
HKT-500 in the Treatment of Adult Patients With Ankle Sprain
The objective of this study is to demonstrate the multiple-dose efficacy and safety of HKT-500 for the treatment of ankle sprain.
- Trial name
- NCT00927641
- Testing
- Ketoprofen Patch
- Where
- 25 sites in United States
- Volunteers
- 240 people
- Sponsor
- Hisamitsu Pharmaceutical Co., Inc.
Hamstring Muscle Strain, Skeletal Muscle Injury
BPC 157 for Acute Hamstring Muscle Strain Repair
This randomized, double-blind, placebo-controlled Phase 2 study evaluates whether pentadecapeptide BPC 157 (BPC-157), an investigational peptide, can speed structural healing and functional recovery after an acute grade II…
- Trial name
- BPC-HAMSTR (NCT07437547)
- Testing
- Pentadecapeptide BPC 157
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Hudson Biotech
Ankle Sprain
Diclofenac Patch for Treatment of Mild to Moderate Ankle Sprain
The primary purpose of this study is to assess the effectiveness of once daily application of a diclofenac sodium patch to the skin near or over the painful area.
- Trial name
- NCT00640705
- Testing
- diclofenac sodium
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- Cerimon Pharmaceuticals
Carpal Tunnel Syndrome
Appropriateness of Carpal Tunnel Syndrome Management Compared With the AAOS Appropriate Use Criteria
Purpose: Carpal tunnel syndrome (CTS) is a common peripheral nerve entrapment disorder among adults that causes upper-extremity disability.
- Trial name
- CTS (NCT05275816)
- Testing
- Comparing the appropriateness of our practice and the usability of the AUC through comparing the actual management provided at our institution with that recommended by the AUC.
- Volunteers
- 136 people
- Sponsor
- Hamad Medical Corporation
Ankle Sprain
Efficacy and Safety of Diclofenac Diethylamine 2.32% Gel in Patients With Acute Ankle Sprain
This study will evaluate the efficacy of diclofenac diethylamine 2.32% gel in the treatment of acute ankle sprain.
- Trial name
- NCT00573768
- Testing
- Diclofenac diethylamine 2.32% gel
- Where
- 29 sites in Germany
- Volunteers
- 271 people
- Sponsor
- Novartis
Acute Pain From Ankle Sprain or Strain
An Efficacy and Safety Study for the Treatment of Mild to Moderate Acute Pain Associated With Ankle Strain or Sprain.
This is a randomized, double blind, placebo controlled, parallel group study to assess the efficacy and safety of K-103-IP compared with placebo patch for treatment of mild to moderate acute pain associated with ankle strain or…
- Trial name
- NCT02089425
- Testing
- K-103-IP
- Where
- 47 sites in United States
- Volunteers
- 384 people
- Sponsor
- Kowa Research Institute, Inc.
Carpal Tunnel Syndrome (CTS)
Evaluation of Dynavisc in Pain Reduction Following Revision Surgery for Persistent or Recurrent Carpal Tunnel Syndrome
The trial will evaluate the efficacy of DYNAVISC in subjects with a diagnosis of persistent or recurrent carpal tunnel syndrome. This is a prospective, multicenter, randomized, evaluator-blinded clinical trial.
- Trial name
- NCT06593977
- Testing
- Dynavisc
- Where
- 4 sites in Belgium, Brazil and 1 more
- Volunteers
- 50 people
- Sponsor
- FzioMed
Carpal Tunnel Syndrome
Safety and Efficacy of a Novel Carpal Tunnel Tissue Manipulation Device in Treating Carpal Tunnel Syndrome
A single-center, prospective, non-randomized study to evaluate the safety and efficacy of a novel carpal tunnel tissue manipulation device in treating symptoms and decreased physical function in subjects previously diagnosed with…
- Trial name
- NCT02534493
- Testing
- Carpal Tunnel Tissue Manipulation Device (CTMD)
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Pressure Profile Systems, Inc.
Pain
A Multicenter Efficacy Study of a Diclofenac+Menthol Gel in Subjects With Ankle Sprain
This Phase III pivotal efficacy study will assess efficacy and onset of pain relief of MFC51123 gel vs. placebo and MFC51123 gel vs.
- Trial name
- NCT02100670
- Testing
- 1% diclofenac sodium plus 3% menthol, 1% diclofenac sodium plus 0.09% menthol, 3% menthol
- Where
- 3 sites in Germany
- Volunteers
- 385 people
- Sponsor
- GlaxoSmithKline
Athletes With Previous Lateral Ankle Sprain(s)
The Spraino Pilot Trial
This pilot study will establish the preliminary effect and safety of using Spraino® to prevent lateral ankle sprains amongst athletes competing in indoor sports at sub-elite level, with a one-year follow-up.
- Trial name
- NCT03311490
- Testing
- Spraino
- Where
- 2 sites in Denmark
- Volunteers
- 510 people, healthy volunteers welcome
- Sponsor
- Spraino
Ankle Sprains
MRX-7EAT Etodolac-Lidocaine Topical Patch in the Treatment of Ankle Sprains
A Randomized, Multi-Center, Double-Blind, Factorial, Comparator and Placebo-Controlled Phase III Trial to Evaluate the Efficacy, Tolerability and Safety of MRX-7EAT Etodolac-Lidocaine Topical Patch in the Treatment of Ankle…
- Trial name
- NCT01198834
- Testing
- MRX-7EAT, Lidocaine, Etodolac
- Where
- 33 sites in United States
- Volunteers
- 600 people
- Sponsor
- MEDRx USA, Inc.
Ankle Sprain 1St Degree, Ankle Sprain 2Nd Degree
Assessment of the Safety and Performance of Ankle Ligament Supports in the Context of a Return to Sport After Sprain
Decathlon has developed Ankle STRONG products which are medical devices that must be positioned around the ankle to limit ankle sprain occurrence. The Ankle STRONG devices cover a range of 3 products (Ankle STRONG 100/500/900).
- Conditions
- Ankle Sprain 1St Degree, Ankle Sprain 2Nd Degree, Ankle Sprain 3Rd Degree
- Trial name
- NCT04599829
- Testing
- AnkleSTRONG100/500/900
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Decathlon SE
Pain
Voltaren Emulgel 2% Acute Ankle Sprain Non Inferiority Study
The purpose of this study is to evaluate the efficacy and safety of diclofenac diethylamine 2.32 percent (%) gel applied twice daily versus diclofenac diethylamine 1.16% gel applied four times daily for 7 days in participants…
- Trial name
- NCT04052620
- Testing
- Diclofenac diethylamine 2.32% gel, Diclofenac diethylamine 1.16% gel
- Where
- 14 sites in China
- Volunteers
- 313 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Sprain
Efficacy Study of a Sensory Feedback Knee Orthosis in Patients Suffering From Unoperated Severe Knee Sprain
Ortheses are commonly used for the repair of damage to the musculoskeletal system. However, immobility, by itself, causes serious side effects that require long and costly rehabilitation.
- Trial name
- ORTHOSENS (NCT01508728)
- Testing
- ORTHOSENS orthosis
- Where
- 3 sites in France
- Volunteers
- 104 people
- Sponsor
- Thuasne
Soft Tissue Injuries, Gouty Arthritis
AMPED Outcomes Registry of Post-ED Pain Management
Study aims to assess patient-recorded outcomes of pain control medications prescribed in the ER after visits for specific painful injuries/illnesses.
- Conditions
- Soft Tissue Injuries, Gouty Arthritis, Fractures, Ureteral Colic
- Trial name
- AMPED (NCT01626235)
- Where
- 11 sites in United States
- Volunteers
- 843 people
- Sponsor
- Radnor Registry Research, Inc
A03 - Digestive System, B03 - Bacteria
Survival Plant-Based
The aim of this study is to explore the potential of a mix of 4 freeze-dried bifidobacteria strains from Danone collection to survive in human gastro-intestinal (GI) tract of healthy volunteers after 14 days of consumption.
- Trial name
- Survi PB (NCT06768229)
- Testing
- Consumption of a freeze-dried strains-mix.
- Where
- France
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Danone Global Research & Innovation Center
Ankle Sprain
HKT-500 in Adult Patients With Ankle Sprain
The objective of this study is to demonstrate the multiple-dose efficacy and safety of HKT-500 for the treatment of ankle sprain.
- Trial name
- NCT00680784
- Testing
- HKT-500 Ketoprofen Topical Patch
- Where
- 30 sites in United States
- Volunteers
- 260 people
- Sponsor
- Hisamitsu Pharmaceutical Co., Inc.