Clinical trials: Spontaneous Breathing Trial in ICU, open to volunteers
Ventilator Weaning, Airway Extubation
Can a Pain Monitor Predict When Postoperative Intensive Care Unit Patients Are Ready to Breathe on Their Own? A Pilot Study
The goal of this observational study is to learn if a chest monitor that tracks heart rhythm can help predict whether adults on a breathing machine after surgery will be able to breathe on their own once the breathing tube is…
- Conditions
- Ventilator Weaning, Airway Extubation, Respiration, Artificial
- Trial name
- NCT07771101
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Seoul National University Hospital
Spontaneous Breathing Trial in ICU
Effect of High-Flow Humidified Oxygen on Ventilatory Work During the Spontaneous Breathing Trial
Weaning from mechanical ventilation (MV) accounts for a significant portion of the total MV duration, and failure to extubate or delayed extubation increases complications (particularly Ventilator-Associated Pneumonia (VAP)) and…
- Trial name
- OTRAVAIL (NCT07724392)
- Testing
- T piece, PSV, HFO
- Volunteers
- 30 people
- Sponsor
- University Hospital, Grenoble
Reverse Triggering, Patient Ventilator Dyssynchrony
Intrinsic Respiratory Rate Assessment During Mechanical Ventilation to Accelerate Spontaneous Breathing and Extubation
The goal of this study is to identify patients with reverse triggering who's the potential to breath spontaneously is hidden because of the ventilator management strategy by performing a simple 30sec-test with includes reducing…
- Trial name
- INTRINSIC (NCT06445049)
- Testing
- brief test
- Volunteers
- 70 people
- Sponsor
- Unity Health Toronto
Mechanical Ventilation Weaning From Mechanical Ventilation Extubation Failure Critical Illness
Delta Pocc During Spontaneous Breathing Trial to Predict Extubation Failure in Mechanically Ventilated Adults (DELTA-EXT)
This prospective observational single-center study will evaluate whether dynamic respiratory stress estimated by delta airway occlusion pressure deflection (Delta Pocc) during a standardized spontaneous breathing trial can…
- Trial name
- DELTA-EXT (NCT07634783)
- Testing
- Delta Pocc Measurement During Spontaneous Breathing Trial
- Where
- Argentina
- Volunteers
- 120 people
- Sponsor
- Sanatorio Parque, Argentina
Spontaneous Breathing Trial in ICU, Spontaneous Breathing Trial
Effectiveness of Pet-Robotic Intervention in Intensive Care Unit Patients
This study aims to develop a novel nursing intervention involving robotic pet companionship to reduce anxiety in patients undergoing spontaneous breathing trials.
- Trial name
- NCT07163247
- Testing
- Robotic pet (PARO) companionship
- Where
- Taiwan
- Volunteers
- 24 people
- Sponsor
- National Taiwan University Hospital
Weaning Invasive Mechanical Ventilation, Weaning-induced Pulmonary Edema
Ultrasound Evaluation of Cardiac Function During Spontaneous Breathing Trials
The goal of this clinical trial is to evaluate the evolution of a cardiac ultrasound index (E/E') during 3 spontaneous breathing trials in Intensive Care Unit (ICU) adults (over 18 years) patients at risk for weaning failure.
- Conditions
- Weaning Invasive Mechanical Ventilation, Weaning-induced Pulmonary Edema, Weaning Failure of Mechanical Ventilation, Spontaneous Breathing Test
- Trial name
- ATARI (NCT06923267)
- Testing
- No Pressure Support No Positive End Expiratory Pressure Spontaneous Breathing Trial, Pressure Support Spontaneous Breathing trial, Humidified High Flow Spontaneous Breathing Trial
- Where
- France
- Volunteers
- 24 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Acute Brain Injury, Mechanical Ventilation
Regional Ventilation Evaluation During Neuro-injury Weaning Study
This study evaluates changes in regional lung ventilation using thoracic electrical impedance tomography (EIT) during the weaning process from mechanical ventilation in ICU patients with acute brain injury.
- Conditions
- Acute Brain Injury, Mechanical Ventilation, Prolonged Weaning, Traumatic Brain Injury
- Trial name
- ReVENtS (NCT07067671)
- Testing
- Internal Thoracic Impedance
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Ventilator Weaning, Respiratory Insufficiency
Diaphragm Ultrasound and Rapid Shallow Breathing Index for Predicting Extubation Success
The purpose of this study is to find out whether diaphragm ultrasound measurements, alone or combined with the rapid shallow breathing index (RSBI), can better predict successful removal of the breathing tube in adult intensive…
- Trial name
- NCT07897617
- Testing
- Diaphragm Ultrasonography, Rapid Shallow Breathing Index
- Volunteers
- 80 people
- Sponsor
- Inonu University
Critical Illness, Intensive Care Units (ICUs)
Surface Electrical Myography, Oxygen Consumption, Effort, and Weaning in the Mechanically Ventilated Patient in the Intensive Care Unit
The goal of this observational study is to measure effort using esophageal pressure measurements, oxygen consumption and diaphragm activity in mechanically ventilated Intensive Care Unit patients during a Spontaneous Breathing…
- Conditions
- Critical Illness, Intensive Care Units (ICUs), Weaning Failure, Mechanical Ventilation
- Trial name
- SERA-Effort (NCT07109570)
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Leiden University Medical Center
Spontaneous Breathing Trial in ICU
Automatic Tube Compensation vs. Pressure Support Ventilation During Spontaneous Breathing Trials in Adults
For patients requiring mechanical ventilation, spontaneous breathing trials (SBTs) are conducted to determine if it is safe to remove the breathing tube. There are multiple methods for conducting SBTs.
- Trial name
- NCT07005505
- Testing
- Pressure Support Ventilation (PSV), Automatic tube compensation (ATC)
- Where
- United States
- Volunteers
- 880 people
- Sponsor
- Rush University Medical Center