Clinical trials: Spontaneous Breathing Trial
Tracheostomy
The Application and Analysis of Diaphragm Electrical Impulse in Adult Patients With Spontaneous Breathing Trial
The aim of this study is to investigate the use of Edi in patients under the endotracheal tube and tracheostomy, and analysis of cardiopulmonary parameters in adult patients.
- Trial name
- NCT05241002
- Where
- Taiwan
- Volunteers
- 4 people
- Sponsor
- Fu Jen Catholic University
Atelectasis, Postoperative Pulmonary, Bariatric Surgery
Postoperative Hypoxemia in Obese Patients
Postoperative atelectasis can cause postoperative hypoxia which might be avoided by applying pressure support during extubation of obese patients undergoing bariatric surgeries.
- Trial name
- RCT (NCT06589011)
- Testing
- Pressure Support Ventilation, spontaneously assisted breathing
- Where
- Egypt
- Volunteers
- 170 people
- Sponsor
- Theodor Bilharz Research Institute
Airway Extubation, Ventilator Weaning
Mechanical Ventilation Reconnection for One Hour After Spontaneous Breathing Trial
The aim of this study is to evaluate the feasibility to perform a future larger clinical trial to analyze whether the mechanical ventilation reconnection for 1 hour after a successful spontaneous breathing trial reduces the risk…
- Trial name
- NCT05999526
- Testing
- Reconnection to mechanical ventilation for 1 hour, Direct extubation
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Centro Hospitalar Unimed de Joinville
Atelectasis, Hypoxemia
Pulmonary Ultrasound for the Assessment of Atelectasis in Anesthetized Children Using a Laryngeal Mask Airway.
This study will use lung ultrasounds (LUS) to evaluate the incidence and severity of intraoperative atelectasis in anesthetized children undergoing minor surgery using a laryngeal mask airway.
- Trial name
- NCT06214312
- Testing
- Lung Ultrasounds
- Where
- Belgium
- Volunteers
- 43 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Weaning Failure, Weaning-induced Pulmonary Edema
Incidence and Risk Factors of Weaning-induced Cardiac Dysfunction: Results From a Multicenter, Observational Study
During weaning from mechanical ventilation, the shift from positive to negative pressure ventilation may be responsible for a cardiac dysfunction that can lead to the development of pulmonary oedema (weaning-induced pulmonary…
- Conditions
- Weaning Failure, Weaning-induced Pulmonary Edema, Spontaneous Breathing Trial
- Trial name
- WIPO (NCT05318261)
- Testing
- Spontaneous breathing trial
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Bicetre Hospital
Ventilator Weaning, Airway Extubation
Can a Pain Monitor Predict When Postoperative Intensive Care Unit Patients Are Ready to Breathe on Their Own? A Pilot Study
The goal of this observational study is to learn if a chest monitor that tracks heart rhythm can help predict whether adults on a breathing machine after surgery will be able to breathe on their own once the breathing tube is…
- Conditions
- Ventilator Weaning, Airway Extubation, Respiration, Artificial
- Trial name
- NCT07771101
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Seoul National University Hospital
Weaning of Mechanical Ventilation, Chronic Obstructive Pulmonary Disease
Spontaneous Breathing Trials Using Pressure-Support or T-Tube in Chronic Obstructive Pulmonary Disease Patients Weaning Mechanical Ventilation
Weaning of mechanical ventilation (MV) is an essential part in management of patients with Chronic Obstructive Pulmonary Disease (COPD) when critically ill. The best strategy to be used has not been established.
- Trial name
- NCT01464567
- Testing
- "T" Tube Spontaneous Breathing Trial, Pressure Support Ventilation
- Where
- 2 sites in Brazil
- Volunteers
- 190 people
- Sponsor
- Hospital Nossa Senhora da Conceicao
Acute Respiratory Distress Syndrome
Effect of Spontaneous Breathing in APRV Mode on Respiratory Physiology of ARDS Patients
This is a single-center, prospective, randomized, three-period crossover physiological study in adult patients with moderate-to-severe acute respiratory distress syndrome (ARDS, PaO₂/FiO₂ ≤150 mmHg).
- Trial name
- SBA-APRV (NCT07798154)
- Testing
- APRV ventilation with low-level spontaneous breathing, APRV ventilation with high-level spontaneous breathing, APRV ventilation with fully suppressed spontaneous breathing
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Mechanical Ventilation, Airway Patency
The Effects of Ketamine on Respiratory Stimulation and Transpulmonary Pressures
Impairment of airway patency is a common cause of extubation failure and opioids and hypnotics can adversely affect airway patency.
- Conditions
- Mechanical Ventilation, Airway Patency, Respiratory Depression
- Trial name
- NCT01969227
- Testing
- Subanesthetic ketamine
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Massachusetts General Hospital
Spontaneous Breathing Trial in ICU
Benefits of Immersive Virtual Reality on Dyspnoea During a Weaning Test in the Intensive Care Unit.
A weaning trial is a test that simulates physiological respiratory conditions after extubation in order to assess the patient's ability to breathe without the assistance of a ventilator.
- Trial name
- RVI-ERS (NCT06434116)
- Testing
- Immersive virtual reality
- Volunteers
- 30 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
ARDS (Acute Respiratory Distress Syndrome)
International Survey for EXTubation Evaluation and Respiratory Dynamics in Acute Respiratory Distress Syndrome
EXTEND ARDS study is an international survey for ventilator weaning and extubation among ARDS patients. This study will be conducted on behalf of the Japanese ARDS Clinical Practice Guideline 2024 Committee as well as endorsement…
- Trial name
- EXTEND ARDS (NCT06598709)
- Where
- Japan
- Volunteers
- 1,000 people
- Sponsor
- Hiroshima University
Transmission, Patient-Professional
Aerosol Particle Concentrations Among Different Oxygen Devices for Spontaneous Breathing Patients With Tracheostomy
For spontaneous breathing patients with tracheostomy, whose lower airway is directly opened to the room air, the aerosol particles generated by the patients would be directly dispersed into the room air, which might be an direct…
- Trial name
- NCT04654754
- Testing
- high-flow high humidity oxygen device with tracheostomy adapter
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Jie Li
Dyspnea
Dyspnea and Cerebral Cortex Activation Measured by fNIRS During Spontaneous Breathing Trial
Background: In Intensive Care Unit (ICU) patients, dyspnea is frequent, severe and exerts unfavorable effects on the short, medium and long term. Detection and quantification rely on the patient's self-reporting abilities.
- Trial name
- WEANIRS (NCT06211738)
- Testing
- no intervention
- Where
- France
- Volunteers
- 22 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Weaning, Spontaneous Breathing Trial
Diaphragmatic Speckle Tracking During Spontaneous Breathing Trial
Currently, measurement of transdiaphragmatic pressure (Pdi) using oesophageal and gastric balloons is the gold standard for the assessment of diaphragmatic effort.
- Conditions
- Weaning, Spontaneous Breathing Trial, Mechanical Ventilation, Speckle Tracking
- Trial name
- DIAST (NCT06009731)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Weaning, Spontaneous Breathing Trial
Prediction Of Pulmonary Edema With Müller Maneuver
The mechanical ventilation weaning must begin as early as possible to limit its complications and requires a spontaneous breathing trial (SBT) before the separation from the ventilator to the patient.
- Trial name
- PoEM (NCT05358405)
- Testing
- Müller maneuver
- Where
- France
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Respiratory Insufficiency
Sedation Versus No Sedation in a Spontaneous Breathing Trial
An important part of how we decide when a patient is ready to have their breathing tube removed is to have a person breathe without any machine breaths while the breathing tube is still in place.
- Trial name
- NCT00366353
- Testing
- Sedation during SBT, No sedation
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Memorial Medical Center
Weaning From Mechanical Ventilation, Extubation
Direct Extubation Versus Extubation After a Spontaneous Breathing Trial in Patients at Low Risk of Extubation Failure
This randomized controlled open label trial aims at comparing a weaning strategy including a spontaneous breathing trial as a prerequisite for extubation to a weaning strategy without a spontaneous breathing trial (direct…
- Trial name
- T-REX (NCT07019636)
- Testing
- Weaning strategy with direct extubation (no spontaneous breathing trial), Weaning strategy with extubation only after a successful spontaneous breathing
- Where
- France
- Volunteers
- 314 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Stability During Surgical Operation, Complication, Postoperative
Clinical Trial of Thoracoscopic Bullectomy Surgery Under Spontaneous Ventilating Anesthesia
With the development of video-assisted thoracoscopic surgery (VATS) techniques and technology for anesthesia control, non-intubated anesthesia with spontaneous ventilation has been widely applied in VATS.
- Conditions
- Stability During Surgical Operation, Complication, Postoperative, Postoperative Hospitalization Time
- Trial name
- NCT03016858
- Testing
- Thoracoscopic Bullectomy Surgery
- Where
- China
- Volunteers
- 320 people
- Sponsor
- Guangzhou Institute of Respiratory Disease
Respiration, Artificial, Ventilator Weaning
Pressure Support Reduction Versus Spontaneous Breathing Trials in Weaning From Ventilation
This study is a comparison of two most commonly used modes of weaning and the outcomes in the two groups.
- Trial name
- NCT00911378
- Testing
- Pressure support ventilation, Spontaneous breathing trials
- Where
- India
- Volunteers
- 130 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Elective Cardiac Surgery
Acceptable Range of Inspiratory Effort During Mechanical Ventilation
Partially assisted mechanical ventilation is ideally titrated to maintain adequate inspiratory muscle activity (i.e. preventing disuse atrophy) while avoiding excessive (i.e. fatiguing) inspiratory loads.
- Trial name
- EFFORT (NCT02838524)
- Where
- Canada
- Volunteers
- 43 people
- Sponsor
- Unity Health Toronto