Clinical trials: Spondylarthritis
Spondyloarthropathy
Identification of Serum Level of Glutathione Peroxidase 4
Analysis of the level of glutathione peroxidase 4 (GPX4) in ankylosing spondylitis and axial psoriatic arthritis patients. The association of glutathione peroxidase 4 (GPX4) with disease activity and severity in ankylosing…
- Trial name
- NCT06554392
- Testing
- Blood sample
- Where
- Egypt
- Volunteers
- 85 people
- Sponsor
- Assiut University
Psoriasis, Ankylosing Spondylitis
A Study of HB0017 Injection in Healthy Volunteers to Evaluate Safety and Tolerability of a Single Subcutaneous Injection in Low-Body-Weight Subjects; and Pharmacokinetics at Different Subcutaneous Injection Sites at the Same Dose
The goal of this clinical trial is to (PART 1) to evaluate the safety and tolerability of a single subcutaneous injection of HB0017 Injection in healthy subjects with low body weight; ( PART 2) to compare the pharmacokinetics…
- Trial name
- NCT07920861
- Testing
- HB0017 Injection
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Huabo Biopharm Co., Ltd.
Spinal Tuberculosis
Cobalt Alloy Pedicle Screw Implantation for Severe Kyphosis Deformity in Spinal Tuberculosis
To investigate whether implantation of cobalt alloy pedicle screws is effective in treating severe kyphosis deformity in spinal tuberculosis, and to determine the factors that are likely to have influenced the curative effects.
- Trial name
- NCT02971644
- Testing
- cobalt alloy pedicle screw implantation
- Volunteers
- 84 people
- Sponsor
- Affiliated Hospital of Hebei University
Ankylosing Spondylarthritis
Ankylosing Spondylitis and Antiphospholipid Antibodies
The main objective is to evaluate the prevalence of anti-phospholipid antibodies (APLA) in patients with ankylosing spondylitis (AS).
- Trial name
- ASAA (NCT02809300)
- Testing
- blood collection
- Where
- France
- Volunteers
- 80 people
- Sponsor
- CHU de Reims
Axial Spondyloarthritis (AxSpA)
Multimodal Pulmonary Rehabilitation in Radiographic Axial Spondyloarthritis
This prospective pilot study aims to evaluate the efficacy of a structured 8-week multimodal pulmonary rehabilitation (PR) program specifically designed for patients with radiographic axial spondyloarthritis (r-axSpA).
- Trial name
- PuRe-axSpA (NCT07430189)
- Testing
- Multimodal Pulmonary Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Balikesir University
Device is Used for Evalution (Event)
Plantar Pressure Values in Patients With Ankylosing Spondylitis
this study was discovered that clinical and radiological characteristics were related to plantar pressure assessments in patients with AS.
- Trial name
- NCT05731635
- Testing
- plantar pressure values
- Volunteers
- 75 people
- Sponsor
- Amasya University
Ankylosing Spondylitis
The Relationship Between Abnormal Modified Schober Index and Demographic Characteristics and Clinical Variables
This study will aim to compare ankylosing spondylitis (AS) participants with abnormal modified Schober index (AMSI) versus AS participants with normal modified Schober index (NMSI) in pain, morning stiffness, balance…
- Trial name
- NCT05589922
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Mustafa Kemal University
Diet Habit, Rheumatologic Disease
Rheumatology Diet Study
This study aims to collect information on rheumatology patients' dietary habits, autoimmune disease activity, dietary changes, disease symptom improvements, and perceptions on their dietary habits and how it affects their…
- Conditions
- Diet Habit, Rheumatologic Disease, Autoimmune Diseases, Rheumatoid Arthritis
- Trial name
- NCT06339957
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- University of Central Florida
Ankylosing Spondylitis
Effects of Cardiovascular Training in Individuals With Ankylosing Spondylitis
To test the effects of a cardiovascular training compared to attention control in a group of AS-patients participating in classic spinal mobility exercise groups (randomized controlled trial)
- Trial name
- NCT00913302
- Testing
- Cardiovascular Training
- Where
- Switzerland
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Arthritis, Psoriatic
A Study to Evaluate the Use of Apremilast in Patients With Psoriatic Arthritis, Naïve to Biological Treatment
Observational, prospective and multicenter study in approximately 25 sites nationwide. The investigators participating in this study will be rheumatologists specializing in this pathology.
- Trial name
- PREVAIL (NCT03828045)
- Testing
- Apremilast
- Where
- 20 sites in Spain
- Volunteers
- 119 people
- Sponsor
- Amgen
Axial Spondyloarthritis
A Study to Evaluate the NSAIDS Sparing Effect of Etanercept in Subjects With Axial Spondyloarthritis
This study will compare the Non Steroidal Anti-Inflammatory Drugs (NSAIDs) sparing effect of etanercept with that of placebo in adult subjects with axial Spondyloarthritis.
- Trial name
- SPARSE (NCT01298531)
- Testing
- etanercept
- Where
- 19 sites in France
- Volunteers
- 90 people
- Sponsor
- Pfizer
Arthritis, Rheumatoid, Spondylarthritis
Follow-up of Person-centered Care of Young Adults With Rheumatic Disease
The purpose of the study is to study how a person-centered structured team caretaking of young adults (16-23 years) with newly diagnosed rheumatoid arthritis (RA), spondartrit (SpA) and psoriasartrit (PsA) in routine clinical…
- Conditions
- Arthritis, Rheumatoid, Spondylarthritis, Arthritis, Psoriatic
- Trial name
- NCT02402894
- Testing
- no intervention
- Where
- Sweden
- Volunteers
- 74 people
- Sponsor
- Vastra Gotaland Region
Ankylosing Spondylitis
Evaluation of Physical Performance in Ankylosing Spondylitis Patients
Ankylosing spondylitis (AS) can cause serious limitations in individuals' physical performance, as it involves the musculoskeletal system and can cause ankylosis and arthritis in both axial and peripheral joints.
- Trial name
- NCT04451681
- Testing
- Cardiopulmonary exercise test
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Ankylosing Spondylitis
Neuropathic Spinal Pain in Ankylosing Spondylitis
The aim of this study is to investigate prevalence of neuropathic spinal pain in AS patients and it's impact on sleep quality. Moreover effects of neuropathic pain on quality of life and fatigue will be assessed.
- Trial name
- NCT04809168
- Testing
- Questionnaires and inventories
- Where
- Turkey (Türkiye)
- Volunteers
- 292 people
- Sponsor
- Bozyaka Training and Research Hospital
Ankylosing Spondylitis, Adolescent Idiopathic Scoliosis
The Prediction and Prevention of Disease by Using Big Data in Motion Analysis
Variable patterns of gait disturbance can be found in patients with spine disease including the problems of gait initiation, freezing of gait, reduced balance and postural control, reduced step lengths, increased step times, and…
- Conditions
- Ankylosing Spondylitis, Adolescent Idiopathic Scoliosis, Gait Analysis
- Trial name
- NCT04867148
- Testing
- Inertial measurement unit sensor-based gait analysis system
- Where
- South Korea
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Pusan National University Hospital
Psoriatic Arthritis
Diet Interventions in Psoriatic Arthritis
The purpose of this study is to learn whether changing diet impacts psoriatic arthritis (PsA).
- Trial name
- DIPSA (NCT04180904)
- Testing
- Diet 1, Diet 2
- Where
- 2 sites in United States, Canada
- Volunteers
- 92 people
- Sponsor
- University of Pennsylvania
Spondyloarthritis, Exercise
A Digital Exercise Intervention in Patients With Spondyloarthritis
This protocol describes a 6-month randomised, controlled exercise trial in patients with axial spondyloarthritis (axSpA) with re-randomization after 3-months.
- Trial name
- SPARK (NCT06462937)
- Testing
- Exercise with supervision, Exercise without supervision
- Where
- Norway
- Volunteers
- 260 people
- Sponsor
- Diakonhjemmet Hospital
PsA (Psoriatic Arthritis)
Effect of Metformin on Carotid Atherosclerosis for Non-diabetic Patients With PsA (CAMPA Study)
Background: Psoriatic arthritis (PsA) is a common chronic inflammatory disease with a prevalence up to 670 every 100,000 subjects.
- Trial name
- NCT05988684
- Testing
- Metformin
- Where
- Hong Kong
- Volunteers
- 24 people
- Sponsor
- Chinese University of Hong Kong
Axial Spondyloarthritis
A Study to Evaluate 608 in Patients With Non- Radiographic Axial Spondyloarthritis (Nr-axSpA)
This study will evaluate the effect and safety of 608 in patients with nr-axSpA.
- Trial name
- NCT06222671
- Testing
- 608
- Where
- 6 sites in China
- Volunteers
- 180 people
- Sponsor
- Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd.
Psoriatic Arthritis
Study to Evaluate the Safety and Efficacy of Secukinumab 300 mg and 150 mg in Adult Patients With Active Psoriatic Arthritis (PsA) After 16 Weeks of Treatment Compared to Placebo
To demonstrate that the efficacy of secukinumab 300 mg at Week 16 was superior to placebo in adult patients with active PsA based on the proportion of patients achieving an American College of Rheumatology 20 (ACR20) response.
- Trial name
- NCT02798211
- Testing
- Secukinumab 300 mg, Secukinumab 150 mg
- Where
- 58 sites in United States, Puerto Rico
- Volunteers
- 258 people
- Sponsor
- Novartis Pharmaceuticals
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