Clinical trials: Split-Thickness Skin Graft
Burns
Study With an Autologous Dermo-epidermal Skin Substitute for the Treatment of Burns in Adults and Adolescents
This phase IIb trial aims to evaluate the efficacy and safety of EHSG-KF (synonym denovoSkin) in comparison to meshed STSG in adults and adolescents with partial deep dermal and full thickness burns.
- Trial name
- NCT03227146
- Testing
- EHSG-KF, STSG
- Where
- 6 sites in Italy, Netherlands and 1 more
- Volunteers
- 14 people
- Sponsor
- CUTISS AG
Wound, Disorder of Skin Donor Site
Clinical Study of Biocellulose Wound Dressing Containing Silk Sericin and PHMB for STSG Donor Sites
1. The wound healing time of STSG donor sites which are treated with the novel biocellulose wound dressing containing silk sericin and PHMB should be less or equal to Bactigras®. 2.
- Trial name
- NCT02643680
- Testing
- The novel biocellulose wound dressing, Bactigras
- Where
- Thailand
- Volunteers
- 32 people
- Sponsor
- Chulalongkorn University
Burn, Trauma
Trial of Zesteem (Estradiol) in Healing of Split Thickness Skin Graft Donor Sites
This trial will assess the effects of Zesteem (estradiol) on the healing of split thickness skin graft donor sites in patients aged 18-85 years.
- Conditions
- Burn, Trauma, Varicose Ulcer
- Trial name
- NCT00426972
- Testing
- estradiol (Zesteem)
- Where
- 30 sites in Germany, Latvia and 2 more
- Volunteers
- 148 people
- Sponsor
- Renovo
Skin Graft Complications
Factors Affecting Split Thickness Skin Graft Success Rates in Patients Who Underwent a Radial Forearm or Fibula Free Flap
Fibula free flaps (FFF) and radial forearm free flaps (RFFF) are necessary to reconstruct parts of the face after cancer surgery, traumas, or debilitating infections.
- Trial name
- NCT04648267
- Testing
- Cast and bolster placement duration, Standard of care
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of Southern California
Wound Heal, Wound Surgical
Clinical Efficacy of Silk Sericin Dressing With Collagen for Split-thickness Skin Graft Donor Site Treatment
To examine the efficacy and safety of sericin dressing with collagen in STSG donor site treatment comparing with Bactigras®. Around 30 patients will be enrolled in this study.
- Conditions
- Wound Heal, Wound Surgical, Donor Site Complication
- Trial name
- NCT04743375
- Testing
- wound dressing application
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Chulalongkorn University
Skin Graft Wounds
Comparing Chitosan Sponge With Hydrocolloid as Dressing for Split-thickness Skin Graft Donor Site Wounds
The goal of this clinical trial is to compare whether chitosan sponge have same clinical efficacy as a hydrocolloid dressing in treating skin graft donor site wounds.
- Trial name
- NCT07472465
- Testing
- Chitosan, Hydrocolloid Dressing (DuoDERM CGF)
- Where
- Malaysia
- Volunteers
- 22 people
- Sponsor
- Hospital Universiti Sains Malaysia
Disorder of Skin Donor Site
Efficacy and Safety of High Absorption Pad in Split-thickness Skin Graft Donor Site Wound
High absorption pad for blood and pus with natural antimicrobial agent or gauze dressing impregnated with paraffin, containing 0.5% chlorhexidine acetate (Bactigras) will be randomly covered on half of split-thickness skin graft…
- Trial name
- NCT04299126
- Testing
- high absorption pad for blood and pus, commercial wound dressing
- Where
- Thailand
- Volunteers
- 24 people
- Sponsor
- Chulalongkorn University
Split-thickness Skin Graft Donor Sites
Evaluation of Opticell Ag on Split-Thickness Skin Graft Donor Sites in Adult Subjects
The purpose of this single center, prospective case series is to evaluate the effective management of split-thickness skin graft donor site wounds using Opticell Ag (Chitosan-based dressing).
- Trial name
- STSG (NCT02642679)
- Testing
- Opticell Ag
- Volunteers
- 19 people
- Sponsor
- Brigham and Women's Hospital
Split Thickness Skin Graft, Wound Healing
Controlled Comparison of a Traditional Dressing Versus a Biologic Dressing Composed of Fetal Fibroblasts and Keratinocytes in Association With a Collagen Matrix on Skin Donor Sites
Cell-based engineered skin substitutes are promising to treat difficult-to-heal acute and chronic wounds such as large/deep burns, ulcers resistant to conventional therapies or surgical wounds.
- Trial name
- CICAFAST (NCT03334656)
- Testing
- biological dressing, Paraffin gauze dressing
- Where
- 2 sites in France
- Volunteers
- 28 people
- Sponsor
- Nantes University Hospital
Wound Heal
Utility of Restrata With Split Thickness Skin Graft to Reconstruct the Forearm Donor Site
Understand association between use of Restrata (Acera Surgical Inc., St. Louis, MO) in forearm flap reconstruction with donor site healing and function
- Trial name
- NCT04829331
- Testing
- Restrata
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Acera Surgical, Inc.
Burns
A Prospective, Descriptive Cohort Study With Prontosan® Wound Gel X in Partial and Full Thickness Burns Requiring Split Thickness Skin Grafts
The purpose of this study is to evaluate the healing of split thickness skin grafts when treated with Prontosan® Wound Gel X in patients with partial and full thickness skin burns.
- Trial name
- NCT01534858
- Testing
- Prontosan Wound Gel X
- Where
- 3 sites in Germany
- Volunteers
- 51 people
- Sponsor
- B. Braun Ltd. Centre of Excellence Infection Control
Surgical Wound
Single-Use Negative Pressure Wound Therapy for Free Flap Donor Sites
Various management options for free flap donor sites that require split thickness skin grafting exist. None has proven superior from both a patient care and a cost standpoint.
- Trial name
- NCT03340025
- Testing
- PICO Single Use Negative Pressure Wound Therapy System, xeroform gauze
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Alabama at Birmingham
Skin Transplantation
Negative Pressure Wound Therapy for Skin Grafts
The repairing of various wounds is always a great challenge in burn surgery and plastic surgery. Skin-grafting is the main therapy.
- Trial name
- NCT02374528
- Testing
- Negative pressure wound therapy, standard pressure bolster dressing
- Volunteers
- 98 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Wound Closure Techniques
Use of 2-octylcyanoacrylate With Full-thickness Skin Grafts
The purpose of this study is to determine whether the use of 2-octylcyanoacrylate during repair of cutaneous surgery wounds with full-thickness skin grafts improves scar cosmesis compared to wound closure with sutures.
- Trial name
- NCT02550574
- Testing
- Wound Closure with 2-octylcyanoacrylate, Wound Closure with 5-0 Vicryl Sutures
- Volunteers
- 50 people
- Sponsor
- University of California, Davis
Skin Graft Disorder, Donor Site Complication
Impact of Prisma on Donor Site Pain
The purpose of this study is to assess the feasibility of evaluating the use of a composite collagen, silver-oxidized regenerated cellulose matrix compared to the standard of care dressing on donor site pain for patients…
- Trial name
- NCT04050124
- Testing
- Promogran Prisma, Standard of care (SOC) dressings
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- NYU Langone Health
Skin Graft Complications
A Comparison of OASIS Wound Matrix With Approved Dressings for Skin Graft Donor Sites
The investigators objective is to compare OASIS wound matrix with other commonly used dressings available for the donor site in split thickness skin grafting in order to determine which dressing provides the best outcome based on…
- Trial name
- OASIS (NCT02994589)
- Testing
- Tegaderm™(Absorbant, 3M), OASIS® wound matrix, Xeroform™
- Sponsor
- Loma Linda University
Wound Healing
Manuka Honey for Wound Care
Since antiquity, honey has been recognized for its healing properties. Literature about the use of medicinal honey for wound care dates back centuries with recent data suggesting its use in patients suffering from burns or…
- Trial name
- NCT02259491
- Testing
- Manuka Honey Dressing
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Transplantation Infection, Wound of Skin
Graft Take and Microbiology in Burns
SPLIT-THICKNESS SKIN GRAFT TAKE AND MICROBIOLOGICAL EVALUATION IN BURNED PATIENTS INTRODUCTION: Infection is cause of increased morbidity and mortality in burn patients, and its control is a major challenge also for skin graft…
- Conditions
- Transplantation Infection, Wound of Skin, Burns, Graft Loss
- Trial name
- NCT01301118
- Volunteers
- 30 people
- Sponsor
- Federal University of São Paulo
Wounds
OxyGenesys Dissolved Oxygen Dressing; Abdominoplasty at Northwestern University
Twelve acute wounds (6 on either side of the umbilicus) will be surgically created in the lower abdominal area. One side of the umbilicus will be randomized to Oxygenesys treatment arm and the other side will be receiving a…
- Trial name
- NCT02591537
- Testing
- OxyGenesys Dissolved Oxygen Dressing
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Halyard Health
Wound Healing
Efficacy of Topical Heparin Spray on Donor Site Wound Healing Time Compared to Conventional Dressing Among Patients Undergoing Split Thickness Skin Grafting
Wound is defined by the breach in dermis of the skin. It can be caused by road traffic accidents, tumor excision, chronic illness like diabetes, bed sores in bedridden patients, burns, insects' bites etc.
- Trial name
- NCT04613336
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences