Clinical trials: Spirometry
Acute Exacerbation, Idiopathic Pulmonary Fibrosis
Early Detection of Acute Exacerbation in Patients With Idiopathic Lung Fibrosis - a Pilot Study
Idiopathic pulmonary fibrosis (IPF) is a chronic disease, leading to poor lung function with a median survival of 2-3 years. Acute exacerbation of idiopathic IPF is a complication associated with a mortality rate > 50%.
- Conditions
- Acute Exacerbation, Idiopathic Pulmonary Fibrosis, Home Spirometry
- Trial name
- NCT03979430
- Testing
- Home spirometry
- Where
- 4 sites in Germany
- Volunteers
- 47 people
- Sponsor
- Heidelberg University
Chronic Obstructive Pulmonary Disease (COPD), Asthma
Predicting Dynamic Inspiratory Muscle Strength in COPD and Asthma Patients
This observational study evaluates whether dynamic inspiratory muscle strength can be estimated in patients with chronic obstructive pulmonary disease (COPD) and asthma using simple clinical and performance-based measurements.
- Trial name
- DIMS-PRED (NCT07598292)
- Where
- Turkey (Türkiye)
- Volunteers
- 123 people
- Sponsor
- Hitit University
Pulmonary Complications
Comparison of BiPAP and ٰIS in Reducing Post CABG Pulmonary Complications
To evaluate the effect of Bi-level Positive Airway Pressure (BiPAP) and Incentive Spirometry (IS) in post CABG patients.
- Trial name
- NCT04700215
- Testing
- BiPAP, Incentive spirometry
- Where
- Pakistan
- Volunteers
- 350 people
- Sponsor
- Chaudhry Pervaiz Elahi Institute of Cardiology
Intensive Care (ICU) Myopathy, Functional Independence
Correlation Between Spirometry and Functional Independence in Adult Post-ICU Patients
Several complications and comorbidities are frequently found in patients admitted to an Intensive Care Unit (ICU), including acquired ICU muscle weakness and physical and cognitive limitations.
- Trial name
- NCT03619915
- Testing
- Spirometry, Functional Independence Measure
- Volunteers
- 197 people
- Sponsor
- Universidade Estadual do Oeste do Paraná
Asthma in Children
Home Air in Agriculture: Pediatric Intervention Trial
This study seeks to reduce exposure to asthmagens in the homes of a community of Latino children residing in an area of intense agricultural production in Eastern Washington by testing the effectiveness of an intervention (high…
- Trial name
- HAPI (NCT04919915)
- Testing
- HEPA air cleaner
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- University of Washington
Coronary Artery Disease, Atheroscleroses
Pulmonary Disease in Patients Referred for Coronary CT
Several studies show an association between chronic obstructive pulmonary disease (COPD) and coronary artery disease (CAD). Besides risk factors such as smoking, both are associated with physical inactivity, advanced age and…
- Conditions
- Coronary Artery Disease, Atheroscleroses, COPD, Respiratory Diseases
- Trial name
- NCT01734629
- Where
- Brazil
- Volunteers
- 205 people
- Sponsor
- University of Sao Paulo General Hospital
Dyspnea, Respiratory Rate
Evaluating the Effectiveness of Incentive Spirometry
Post-operative pulmonary complications (PPCs) have a major impact on patients and healthcare expenses. The goal of perioperative respiratory therapy is to improve airway clearance, increase lung volume, and mitigate atelectasis.
- Conditions
- Dyspnea, Respiratory Rate, Oxygen Saturation, Oxygen Requirements
- Trial name
- NCT02952027
- Testing
- Use-recording, patient-reminder alarm for incentive spirometry
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Lifespan
Chronic Obstructive Pulmonary Disease
Safety and Tolerability QAT370 Compared to Tiotropium in Patients With Chronic Obstructive Pulmonary Disease
This study will assess the safety and tolerability of QAT370 compared to tiotropium in patients with COPD.
- Trial name
- NCT00532350
- Testing
- QAT370, Tiotropium
- Where
- 3 sites in Germany
- Volunteers
- 22 people
- Sponsor
- Novartis
Down Syndrome, Dysphagia, Oropharyngeal
Pulmonary Health in Children With Down Syndrome
The goal of the study is to learn more about tests that can assess lung health in children with Down syndrome.
- Trial name
- NCT04398862
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of Colorado, Denver
Lung Diseases, COPD
Screening for Lung Health by a Mobile Device
Respiratory diseases are a common cause of mortality and disability at the worldwide and national levels. Many of them are characterized by underdiagnosis and diagnosis in advanced stages of the disease, and in most of them…
- Trial name
- SMILE (NCT06232356)
- Testing
- Mobile Web App
- Where
- 2 sites in Spain
- Volunteers
- 275 people
- Sponsor
- SEPAR- EPOC
Chronic Obstructive Pulmonary Disease (COPD)
Efficacy of Fixed Combination of Beclometasone + Formoterol + Glycopyrrolate Versus Foster® in COPD
Randomized,double-blind,multicenter,multinational,parallel-group,Phase III study to demonstrate the superiority of the triple fixed combination of beclometasone + formoterol + glycopyrrolate (BDP/FF/GB) administered via…
- Trial name
- TRILOGY (NCT01917331)
- Testing
- Beclometasone/Formoterol/Glycopyrrolate, Beclometasone/Formoterol
- Where
- Hungary
- Volunteers
- 1,368 people
- Sponsor
- Chiesi Farmaceutici S.p.A.
Covid19
Pulmonary Rehabilitation of Patients With a History of COVID-19
This study will determine the impact of pulmonary rehabilitation on quality of life, body composition and respiratory function in patients with a history of COVID-19.
- Trial name
- NCT04751617
- Testing
- Pulmonary rehabilitation
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- University of Rzeszow
Smoking Cessation, COPD
Effectiveness of Spirometry as a Motivational Tool to Quit Smoking
The aim of the study is to asses the efficacy of the spirometry and a minimal smoking cessation counselling intervention to quit smoking after a year in patients older than 40 years, smokers of more than 10 packs-year and without…
- Trial name
- ESPIMOAT (NCT01821885)
- Testing
- Spirometry and a brief advice to quit smoking, Brief advice to quit smoking
- Where
- Spain
- Volunteers
- 335 people
- Sponsor
- Basque Health Service
Asthma, Pulmonary Function
Vitamin C to Decrease Effects of Smoking in Pregnancy on Infant Lung Function (VCSIP) Longer Term Follow Up
The overall aims of this protocol are to determine whether prenatal supplementation with vitamin C to pregnant smokers can improve pulmonary function at 10 years of age in their offspring.
- Conditions
- Asthma, Pulmonary Function, Wheezing, In Utero Nicotine
- Trial name
- VCSIP (NCT06106646)
- Testing
- No active intervention in this protocol (previously randomized to Vitamin C)
- Where
- 2 sites in United States
- Volunteers
- 225 people
- Sponsor
- Oregon Health and Science University
Cystic Fibrosis
Airway Clearance Therapy on Hyperpolarized 129Xenon and MRI
This is an observational cohort study building on an existing protocol at our institution recruiting CF patients who are 6-21 years old with one or two copies of the F508del CFTR mutation.
- Trial name
- NCT03593434
- Testing
- hyperpolarized Xenon gas
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Pulmonary Disease, Chronic Obstructive
Prevalence of Chronic Airway Obstruction in Subjects With a History of Cigarette Smoking in a Primary Care Setting
This is a cross-sectional study to determine the prevalence of symptomatic airway obstruction using the LFQ as a screening tool in primary care patients with a history of cigarette smoking and to provide descriptive data of this…
- Trial name
- NCT01013948
- Testing
- Non-Interventional
- Where
- 40 sites in United States
- Volunteers
- 1,574 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Pulmonary Disease
Validation of Structured Light Plethysmography
Measurements of Structured Light Plethysmography (SLP) using a chest wall movement based method will be compared to those obtained by spirometry using a flow based pneumotachograph method.
- Trial name
- SLPvsPNT (NCT02598336)
- Testing
- Structured Light Plethysmography, Pneumotachograph Spirometry
- Where
- United Kingdom
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Pneumacare Ltd
Idiopathic Pulmonary Fibrosis
Treating People With Idiopathic Pulmonary Fibrosis With the Addition of Lansoprazole
IPF is a progressive scarring lung condition causing coughing and breathlessness. IPF patients often have reflux disease meaning stomach acid may be breathed into the lungs, potentially damaging them.
- Trial name
- TIPAL (NCT04965298)
- Testing
- Lansoprazole
- Where
- 57 sites in United Kingdom
- Volunteers
- 298 people
- Sponsor
- Norfolk and Norwich University Hospitals NHS Foundation Trust
Rib Fractures, Trauma
Continuous Erector Spinae Plane Blocks for Rib Fractures
Rib fractures are one of the most common injuries in trauma patients. These fractures are associated with significant pain as well as decreased ability to inspire deeply or cough to clear secretions, which together lead to…
- Conditions
- Rib Fractures, Trauma, Anesthesia, Anesthesia, Local
- Trial name
- NCT04558281
- Testing
- Active ropivacaine 0.3% erector spinae plane perineural administration
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of California, San Diego
Cerebrovascular Disorders
The Manifestation of Surface EMG of Swallowing Muscles in Stroke Patients With Respiratory Muscle Training
Purpose: To investigate of the respiratory function and swallowing function after respiratory muscle training, and the manifestation of surface EMG of swallowing muscles, and the lateralization of placement of electrodes in…
- Trial name
- NCT03767998
- Testing
- Respiratory muscle training for IMST, Regular Rehabilitation, Respiratory muscle training for EMST
- Where
- Taiwan
- Volunteers
- 46 people
- Sponsor
- Chang Gung Memorial Hospital