Clinical trials: Spine Surgery, open to volunteers
Postoperative Cognitive Complications, Delirium
Prospective Observational Multimodal Neuromonitoring During High-Risk Adult Surgery
This is a prospective observational cohort study of adult patients undergoing high-risk surgery at UT Southwestern Medical Center.
- Conditions
- Postoperative Cognitive Complications, Delirium, Perioperative/Postoperative Complications, Brain Injuries
- Trial name
- NCT07577726
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Texas Southwestern Medical Center
Spine Fusion, Spine Injury
Spine Surgery Video Observation Study. The Creation of a Benchmark Video (RGB-Depth) Dataset to Investigate the Feasibility of Developing a Markerless Tracking System for Spine Surgery.
The primary study objective is to build a video dataset, consisting of both colour and depth information, of spine surgery that includes both 'open' and 'minimally invasive' (MIS) surgeries.
- Conditions
- Spine Fusion, Spine Injury, Spine Degeneration, Navigation, Spatial
- Trial name
- SPIVOS (NCT06580379)
- Testing
- Spine surgery
- Volunteers
- 25 people
- Sponsor
- Imperial College London
Spinal Fusion, Spinal Stenosis
Vancomycin Powder Combined With Autogenous Bone Graft as a Prevention for Post-operative Infection for Spine Surgery
Deep surgical site infection (DSSI) is one of the most challenging complications for spinal surgeons and can lead to a poor clinical outcome.
- Conditions
- Spinal Fusion, Spinal Stenosis, Spondylolisthesis
- Trial name
- NCT03883022
- Testing
- with U-VANCO (vancomycin hydrochloride), without U-VANCO (vancomycin hydrochloride)
- Where
- Taiwan
- Volunteers
- 400 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Comparative Effectiveness Research, Regional Block
Serratus Posterior Superior Intercostal Plane Block Versus Erector Spinae Plane Block in Thoracic Spine Surgeries
Spinal surgeries coincide with high level of pain due to extensive dissection and muscle retraction so inadequate pain control delays patient recovery, rehabilitation and also is an important source of patient dissatisfaction…
- Trial name
- NCT07646184
- Testing
- Serratus Posterior Superior Intercostal Plane Block, Erector spinae block
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Tanta University
Pedicle Screw Accuracy, Robot
Evaluation of the Accuracy of the eCential Robotics Robot in Spinal Surgery
Spinal surgery has evolved considerably over the years, and the introduction of advanced technologies has played a crucial role in improving clinical outcomes.
- Conditions
- Pedicle Screw Accuracy, Robot, Navigation, Spine
- Trial name
- Robotec Amiens (NCT07421752)
- Testing
- eCential Robotics solution
- Where
- France
- Volunteers
- 45 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Spine Pain, Spine Surgery
Influence of Pre-operative Back Muscle Exercise on Post-operative Outcomes After Spine Surgery
The purpose of this research study is to gather more information about how improving back muscle function before surgery might influence what happens to the spine and function after surgery.
- Trial name
- NCT06808022
- Testing
- Preoperative Resistance Exercise
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of California, San Diego
Spinal Metastasis
RELIEVE: Research on Effectiveness of Surgery and Radiotherapy on Relieving Spine Tumor Pain in Patients with Vertebral Metastases
This is a prospective, multicenter, observational study focusing on assessing and managing pain in patients with metastatic spinal tumors.
- Trial name
- RELIEVE (NCT06746103)
- Testing
- Surgery
- Volunteers
- 250 people
- Sponsor
- AO Foundation, AO Spine
Anterior Cervical Spine Surgery
ACSS Approach on Dysphagia
Anterior cervical spine surgery (ACSS) is a procedure for the treatment of several neck problems. Even though the procedure is overall safe and effective, there are possible complications after surgery, which include problems…
- Trial name
- NCT07533864
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Hamilton Health Sciences Corporation
PPAP, Spine Fusion
Personalized Perioperative Analgesia Platform (PPAP) for Pediatric Spine Fusion Surgery (sIRB)
The purpose of this collaborative CTSA application is to develop an innovative perioperative precision analgesia platform (PPAP) to improve analgesia and reduce serious immediate and long-term adverse outcomes of perioperative…
- Trial name
- PPAP Spine (NCT05367609)
- Testing
- Preoperative Genotyping
- Where
- 5 sites in United States
- Volunteers
- 300 people
- Sponsor
- Senthil Sadhasivam
Lumbar Spine Degenerative Changes, Lumbar Spine Surgery
Rehabilitation With Empowered STrategies to Optimize REcovery
The main goal of this clinical trial is to understand the benefits of remotely delivered Empowered Relief in patients undergoing lumbar spine surgery.
- Trial name
- RESTORE (NCT07406997)
- Testing
- Empowered Relief, Education
- Where
- 4 sites in United States
- Volunteers
- 100 people
- Sponsor
- Vanderbilt University Medical Center
Spine Degeneration, Spine Disorder
Rate of Bone Union After Surgery With Stand-alone Fibergraft
Some people have back problems caused by degenerative conditions or instability of the spine (eg. Spondylolisthesis). These problems can lead to pain, nerve issues, or difficulties in walking.
- Conditions
- Spine Degeneration, Spine Disorder, Spine Pain, Spine Fusion
- Trial name
- Fibergraft (NCT07199075)
- Testing
- Questionnaires, Computer Tomography
- Where
- Netherlands
- Volunteers
- 80 people
- Sponsor
- AO Innovation Translation Center
Medium-/Long-segment Spinal Fusion Patients, Spine Surgeons
Evaluation of an Online Peri-operative Health Education Platform for Patients Undergoing Spine Surgery: Ready Set Recover
Chronic back pain is the world's leading cause of disability, with spine surgery being a common yet costly intervention. However, many patients experience suboptimal recovery, with persistent pain and functional limitations…
- Conditions
- Medium-/Long-segment Spinal Fusion Patients, Spine Surgeons, Chronic Low Back Pain, Scoliosis Patients
- Trial name
- NCT07766824
- Testing
- Ready Set Recover
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National University of Natural Medicine
Degenerative Disc Disease, Craniocervical Injuries
Posterior Cervical Fixation Study
The objective of this study is to evaluate the safety and performance of occipito-cervico-thoracic spine surgery using posterior fixation as measured by reported complications, radiographic outcomes, and patients reported…
- Conditions
- Degenerative Disc Disease, Craniocervical Injuries, Cervical Radiculopathy, Cervical Disc Disease
- Trial name
- NCT04770571
- Testing
- observational study
- Where
- 7 sites in United States
- Volunteers
- 150 people
- Sponsor
- NuVasive
Spine Fusion, Postoperative Pain
Suzetrigine (Journavx) for Pain Management After Spine Surgery
This prospective, single-center interventional study will evaluate the effect of suzetrigine (Journavx), a selective NaV1.8 inhibitor, on postoperative opioid requirements in patients undergoing spine surgery.
- Trial name
- NCT07829718
- Testing
- Suzetrigine (Journavx)
- Volunteers
- 110 people
- Sponsor
- Ohio State University
Spine Metastases
Post Operative RT for Limited Spine Metastases
To evaluate patients with limited spine metastases treated with total spondylectomy followed by conventional radiotherapy or debulking surgery followed by SBRT or conventional RT.
- Trial name
- NCT05495399
- Testing
- Spondylectomy, SBRT
- Where
- Taiwan
- Volunteers
- 111 people
- Sponsor
- National Taiwan University Hospital
Lumbar Degenerative Spondylolisthesis
Clinical Study on the Therapeutic Efficacy of Biportal Endoscopic Decompression Spine Surgery and Lumbar Decompression Fusion Surgery in the Treatment of Degenerative Lumbar Spondylolisthesis
This study aims to systematically evaluate the therapeutic efficacy of dual-channel endoscopic spinal decompression versus lumbar decompression with fusion for degenerative lumbar spondylolisthesis.
- Trial name
- NCT07289737
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Spine Surgery
SpinePal Open Pilot
SpinePal is a self-guided digital intervention developed for patients undergoing spine surgery. The goal of this study is to learn if SpinePal is acceptable to people undergoing spine surgery.
- Trial name
- NCT07737912
- Testing
- SpinePal
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Trustees of Dartmouth College
Pain, Postoperative
Methadone for Post-operative Spine Surgery
The goal of this prospective cohort study is to evaluate the clinical effects of post-induction methadone on perioperative pain control, opioid requirements, and recovery outcomes in adult patients undergoing elective spine…
- Trial name
- NCT07517679
- Testing
- Methadone, Standard of care
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Brandon Knopp
Postoperative Pain, Lumbar Surgery
Retrolaminar Analgesia for LuMbar Surgery
This randomized controlled trial evaluates the effectiveness of ultrasound-guided retrolaminar nerve block in addition to standard multimodal analgesia for postoperative pain management in patients undergoing lumbar spine…
- Conditions
- Postoperative Pain, Lumbar Surgery, Back Pain Lower Back Chronic, Opioid Analgesia
- Trial name
- REALM (NCT07334288)
- Testing
- Ultrasound-Guided Retrolaminar Block, Standard Analgesia
- Where
- Chile
- Volunteers
- 50 people
- Sponsor
- Universidad de los Andes, Chile
Cerebral Desaturation Events, Spine Surgeries
Mg Sulfate Versus Dexmedetomidine on Cerebral Oxygen Saturation
This study is to evaluate the effects of dexmedetomidine and magnesium sulfate on cerebral oxygen saturation in patients undergoing spine surgeries as adjuvant to general anesthesia guided by cerebral oximetry.
- Trial name
- mg/dex/rSO2 (NCT06848595)
- Testing
- spine surgery, Magnesium sulfate, Dexmedetomidine
- Volunteers
- 90 people
- Sponsor
- Tanta University