Clinical trials: Spine Metastasis
Solid Tumors, Spine Metastasis
A Study of Kyphoplasty and Vertebroplasty in the Treatment of Spine Metastases
Conventional vertebroplasty is an effective option in the treatment of bone lesions (osteoporotic and neoplastic). It is indicated as an analgesic treatment and aims at reinforcing a compressed vertebrae or at risk of fracture.
- Trial name
- KYPHO-01 (NCT02700308)
- Testing
- Kyphoplasty, Conventional vertebroplasty
- Where
- 2 sites in France
- Volunteers
- 31 people
- Sponsor
- Centre Leon Berard
Unilateral Headache, Musculoskeletal Neck Pain
Effects of Cervical Manual Therapy on Cervicogenic Headache
The effects of cervical spine manual therapy, including mobilization and manipulation, on cervical spine range of motion, joint position sense, and balance is unknown among individuals with cervicogenic headache.
- Trial name
- NCT03385889
- Testing
- Cervical Spine Mobilization, Cervical Spine Manipulation
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Shenandoah University
Cervicogenic Headache
Thrust Joint Manipulation and Reverse SNAGS (Sustained Natural Apophyseal Glides) in Cervicogenic Headache
The purpose of the study was to compare the effect of upper cervical thrust joint manipulation and reverse Sustained Natural apophyseal Glide on intensity of pain, pain pressure threshold, range of motion and headache disability…
- Trial name
- NCT04521218
- Testing
- Thrust Joint Manipulation, Reverse Sustained Natural apophyseal glides
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Cervicogenic Headache, Headache
Effects of Manual Therapy on the Upper Cervical Spine Combined With Exercise vs Isolated Exercise in Patients With Cervicogenic Headache.
Cervicogenic headache is defined as unilateral headache associated with neck pain. Effect of manual translatoric therapy of the upper cervical spine associated with cervical exercises in these patients is currently unknown.
- Trial name
- NCT04401501
- Testing
- Manual Therapy and Exercises, Exercise
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad de Zaragoza
Primary or Metastatic Central Nervous System (CNS) Tumor
Collection of Tumor Tissue, Blood and Spinal Fluid From Patients With Brain or Spine Tumors
The purpose of the study is to collect samples of brain or spine tumors. Memorial Sloan-Kettering Cancer Center would then store them for use by researchers who study brain or spine cancer and try to find better ways of treating…
- Trial name
- NCT00580463
- Where
- United States
- Volunteers
- 1,128 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Secondary Malignant Neoplasm of Spine
Single Versus Multiple Fractionated SSRS for Spinal Metastases
The investigators proposed this randomized study to determine the feasibility of delivering single-fraction 16-Gy versus 3-fraction 24-Gy toward spine metastatic lesion and to evaluate their toxicity profiles.
- Trial name
- NCT02608866
- Testing
- SF-SSRS, MF-SSRS
- Where
- Taiwan
- Volunteers
- 68 people
- Sponsor
- National Taiwan University Hospital
Vertebral Bony Metastases
Isometric Muscle Training in Patients With Spinal Bony Metastases Under Radiation Therapy
Standard indications for palliative radiation of bony metastases include pain, spinal cord compression, and impending pathologic fractures.
- Trial name
- DISPO (NCT01409720)
- Testing
- exercise
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Heidelberg University
Spine Tumor, Vertebral Metastasis
MOVEMENT ANALYSIS IN PATIENTS UNDERGOING VERTEBRECTOMIES FOR SPINE ONCOLOGY: A PILOT STUDY
Analyze the geometric and kinematic parameters of the spine in patients undergoing vertebrectomy through gait analysis, both during the execution of motor tasks such as walking, standing, and basic trunk movements, with the aim…
- Conditions
- Spine Tumor, Vertebral Metastasis, Vertebral Column Mass
- Trial name
- NCT07326969
- Testing
- vertebrectomy
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- Istituto Ortopedico Rizzoli
Bone Metastases
EXercise Enhancement After RadioTherapy for Bone Metastases
The purpose of this study is to evaluate the safety, feasibility, and acceptability of a structured, supervised exercise program combined with standard palliative radiotherapy for patients with painful non-spine bone metastases…
- Trial name
- EXERT-BM (NCT06470503)
- Testing
- Exercise Program
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University Health Network, Toronto
Cervicogenic Headache, Whiplash Injuries
Manipulation and Dry Needling in Patients With Cervicogenic Headache and WAD II
The purpose of this research is to compare two different approaches for treating patients with cervicogenic headaches associated with type II whiplash associated disorder: non-thrust mobilization and exercise versus thrust…
- Trial name
- NCT06502951
- Testing
- Dry Needling,Thrust Manipulation, Exercise,Non-thrust Mobilization
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Alabama Physical Therapy & Acupuncture
Spinal Metastases
Surgical Spinal Decompression of Metastatic Spinal Cord Compression, Minimal Access Versus Open Surgery
The investigators wish to evaluate the effect of minimal access spinal surgery compared to traditional open surgery spinal surgery in patients with metastatic spinal cord compression.
- Trial name
- NCT01865942
- Testing
- open surgery, Minimal access surgery
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Scoliosis
Effectiveness of Bracing in Preventing Scoliosis in Children With Spinal Cord Injury
The purpose of this study is to determine whether full-time high dose prophylactic bracing (23 hours or more per day) is more effective than low dose bracing (12 hours or less per day) in preventing or delaying spinal curve…
- Trial name
- NCT00256672
- Testing
- Thoraco-Lumbar-Sacral-Orthoses (TLSO) / Flex-Foam
- Where
- 3 sites in United States
- Volunteers
- 88 people
- Sponsor
- Shriners Hospitals for Children
Metastatic Epidural Spinal Cord Compression
Phase I Study of Feasibility of Single Session Spine Stereotactic Radiosurgery (SSRS) in the Primary Management in Patients With Inoperable, Previously Unirradiated Metastatic Epidural Spinal Cord Compression (MESCC)
The goal of this clinical study is to learn the feasibility of using a single session of radiation, known as spine stereotactic radiosurgery (SSRS), to treat metastatic epidural spinal cord compression.
- Trial name
- NCT01254903
- Testing
- Stereotactic Radiosurgery (SSRS)
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- M.D. Anderson Cancer Center
Metastatic Bone Tumor
ERAS Anesthetic Care for Metastatic Spine Cancer Resection
Spinal metastases account for 60% of all malignant bone metastases and represent a medically important treatment goal. For patients with malignant tumors diagnosed at this stage, performing En bloc spondylectomy with wide margin…
- Trial name
- NCT05427825
- Testing
- ERAS anesthetic care, Standard anesthetic care
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Metastatic Epidural Spinal Cord Compression
Surgical Versus Nonoperative Treatment of Metastatic Epidural Spinal Cord Compression
The aim of this trial is to evaluate the differences in pain relief, neurological function, quality of life and survival in patients with metastatic epidural spinal cord compression (MESCC) who are managed with a combination of…
- Trial name
- MESCC (NCT00634426)
- Testing
- Surgical excision of the metastatic process, Radiotherapy of the metastatic spine process
- Where
- 10 sites in United States, Canada
- Volunteers
- 163 people
- Sponsor
- AOSpine North America Research Network
Metastatic Malignant Neoplasm in the Spine, Metastatic Malignant Solid Neoplasm
Cement Augmentation in Preventing Vertebral Body Compression Fracture Following Spine Stereotactic Radiosurgery in Patients With Solid Tumors and Spinal Metastases
This randomized phase II trial studies how well cement augmentation works in preventing vertebral body compression fracture following spine stereotactic radiosurgery in patients with solid tumors that have spread to the spine.
- Trial name
- NCT02387905
- Testing
- Management of Therapy Complications, Quality-of-Life Assessment, Questionnaire Administration
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- M.D. Anderson Cancer Center
Metastatic Spinal Tumors, Spinal Cord Compression
Postoperative Neurological Recovery and Risk Factor Analysis in Patients With Paralysis Due to Spinal Metastases
Metastatic spinal tumors represent a common and devastating complication in patients with advanced solid malignancies. Up to 40% of cancer patients may develop spinal metastases during the course of their disease, often resulting…
- Conditions
- Metastatic Spinal Tumors, Spinal Cord Compression, Paralysis, Neurological Deficits
- Trial name
- NCT07527728
- Volunteers
- 150 people
- Sponsor
- Shanghai Changzheng Hospital
Spinal Metastases
D20054;LITT for Spine Tumors
The objective of this clinical study is to evaluate the efficacy and safety of spinal laser interstitial therapy in the treatment of metastatic spinal tumors.
- Trial name
- NCT06548061
- Testing
- ClearPoint Prism
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Degenerative Arthropathy of Lumbar Spinal Facet Joint
Prognostic Factors in Zygapophyseal Osteoarthritis Infiltration: a Prospective Cohort Study
Magnet Resonance Image findings of facet osteoarthritis and patient characteristics are prognostic factors for improving or worsening the clinical outcome after treatment with facet infiltration.
- Trial name
- NCT03304730
- Where
- Brazil
- Volunteers
- 147 people
- Sponsor
- Hospital Israelita Albert Einstein
Postdural Puncture Headache
Lumbar Spine Ultrasound of Patients With Previous Accidental Dural Puncture During Labour Epidural
Accidental dural puncture is a potential complication of epidural analgesia for labour and delivery. When it happens, it may cause debilitating headaches and other symptoms that prevent mothers from talking care of their…
- Trial name
- NCT00465166
- Testing
- Ultrasound
- Where
- Canada
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital