Clinical trials: Spine Injuries and Disorders
Neurologic Deficits
NeuroVision vs Standard Neuromonitoring
The purpose of this study is to perform a prospective, randomized, controlled clinical trial to assess the utility of IONM in patients undergoing primary, single or multilevel lateral spinal procedures.
- Trial name
- NCT04639297
- Testing
- NeuroVision® IONM, Hospital Based IONM
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Intervertebral Disc Compression, Muscle Atrophy
50% Body Weight Reverses Stature, Lumbar Disc Expansion and Vertebral Compliance by Hyper-Buoyancy Floatation.
Study with the aim to see the effect on a space ground analogue , Hyper-Buoyancy Floatation (HBF) on lumbar column and the effect of a supplementary 50% of an axial load.
- Conditions
- Intervertebral Disc Compression, Muscle Atrophy, Spine Injury
- Trial name
- NCT05590754
- Testing
- Hyper-buoyancy Floatation (HBF), Axial Load after 4h of HBF
- Where
- 2 sites in Spain, United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Madrid
Whiplash Injuries, Whiplash Injury of Cervical Spine
Clinical Efficacy of Diazepam After Whiplash
Whiplash injury is very common and lot of patients which suffered the injury have chronic symptoms despite different treatment options. One of main symptoms include muscle spasm and pain caused by neck movement.
- Trial name
- NCT05041985
- Testing
- Diazepam Tablets
- Where
- Bosnia and Herzegovina
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Edin Mešanović
Degenerative Spine Diseases, Surgical Wound
Effect of Topical Tranexamic Acid on Postoperative Drainage in Minimally Invasive Transforaminal Lumbar Interbody Fusion (MI-TLIF)
The randomized controlled study which compare the efficacy outcomes (reducing blood loss and drainage output in patients) in patients undergoing single-level minimally invasive transforaminal lumbar interbody fusion (MI-TLIF) and…
- Trial name
- NCT06427850
- Testing
- Tranexamic acid, Normal saline
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Thanawan Longsuwan
Injury Leg, Back Pain
Assessment of Effectiveness of Neuromuscular Training in Treatment of Lumbar Spine in Football Players
The project aims to assess the effectiveness of neuromuscular training according to the concept of Kinetic Control (KC) in prevention and treatment of lumbar spine and knee pain and in reduction of risk of injury in female…
- Conditions
- Injury Leg, Back Pain, Sport Injury, Training Group, Sensitivity
- Trial name
- NCT04134741
- Testing
- Kinetic Control
- Where
- Poland
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- John Paul II University in Biała Podlaska
Analgesia
Inter-semispinal Fascial Plane Block (ISPB) Versus Erector Spinae Plane Block (ESPB) in Posterior Cervical Spine Surgery
Recent advances in regional anesthesia techniques have aimed to provide more targeted and effective pain relief. Among these, the erector spinae plane (ESPB) block, the multifidus cervicis plane (MCP) block, and the paraspinal…
- Trial name
- NCT07340801
- Testing
- Bupivacaine
- Where
- Egypt
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Kyphosis, Vertebral Fracture
A Study of Effects of Age and Hyperkyphosis on Spine Motion and Loading
We are studying how spine movement changes with age, and when people have vertebral fractures (cracks in the bones of the spine) or hyperkyphosis (a forward stooped posture).
- Trial name
- NCT03008902
- Testing
- Near-infrared passive motion capture recording
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Shoulder Pain, Shoulder Impingement Syndrome
Thoracic Spine and Shoulder Kinematics and Muscle Activation in Rock Climbers With Shoulder Pain
Background and Purpose: Rock climbing has been a popular sport in recent years. Rock climbing includes various open-chain and closed-chain arm movements.
- Trial name
- NCT05950360
- Testing
- Electromagnetic tracking system, surface electromyography
- Where
- Taiwan
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Lateral Epicondylitis
Role of Cervical Spine Mobilization on Lateral Epicondylitis
The study's primary goal is to examine the effectiveness of Mulligan's technique in reducing hyperalgesia in lateral epicondylitis, focusing on cervical spine, while also investigating its influence on central sensitization in…
- Trial name
- NCT06271915
- Testing
- SNAGs - eccentric exercise
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Shoulder Impingement Syndrome
Short-term Effects of Thoracic Manipulation in Shoulder Impingement
The hypothesis of this study is that thoracic spine manipulation would reduce pain in subjects with SIS and cause changes in scapular kinematics and muscle activity in subjects with impingement symptoms and in asymptomatic…
- Trial name
- NCT02083796
- Testing
- Shoulder impingement_TSM, Asymptomatic_TSM
- Where
- Brazil
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sao Carlos
Prevention, Rehabilitation
Dysphagia and Cervical Spine Disorders in Patients With Brain Lesions
The research is about a prospective study conducted in patients suffering from dysphagia and cervical spine disorders and how they are interrelated.
- Trial name
- DysphagCerv (NCT01418105)
- Testing
- Videofluroscopic swallow study (VFSS), cervical spine isometric exercises, Fiberoptic endoscopic esophageal study (FEES)
- Where
- Greece
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Ioannina
Diabetes Mellitus, Type 1, Bone Fracture
Prevalence of Vertebral Fractures in Patients With Type 1 Diabetes
Background : Type 1 diabetes is associated with an increased risk of fractures. The mechanisms accounting for this bone fragility are not yet fully understood.
- Conditions
- Diabetes Mellitus, Type 1, Bone Fracture, Bone Health
- Trial name
- DenSiFy (NCT04064437)
- Testing
- Clinical tests, Biochemical tests, DXA scan
- Where
- 2 sites in Canada
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Concussion
Primary Prevention of Concussion in Youth Ice Hockey Players
1. Background and Rationale: Little is currently known about intrinsic risk factors for sport-related concussion in youth ice hockey players.
- Trial name
- NCT03360786
- Testing
- Specific intervention, Control intervention
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Sport Injury Prevention Research Centre
Rugby, Craniocerebral Trauma
Effectiveness of a Quick Release Dynamic Muscle-strengthening Program on Dynamic Stabilization of the Cervical Spine
The goal of this clinical trial is to learn if Quick Release dynamic strengthening of the cervical spine extensor muscles' reflex could improve dynamic stabilisation capacities of the cervical spine by reducing muscle activation…
- Conditions
- Rugby, Craniocerebral Trauma, Cervical Spine Injury
- Trial name
- CERVITRAIN (NCT06545006)
- Testing
- isometric contractions, stroboscopic glasses, Quick Release
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Spinal Fractures
A Safety and Efficacy Study for Treatment of Painful Vertebral Compression Fractures Caused by Osteoporosis
Doctors are studying an investigational treatment to be used during the vertebroplasty procedure when treating vertebral compression fractures (spine fractures) that may help to reduce pain and restore mobility.
- Trial name
- NCT00290862
- Testing
- Percutaneous Vertebral Augmentation of compression fractures
- Where
- 18 sites in United States
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- Orthovita d/b/a Stryker
Scoliosis, Scoliosis; Adolescence
Study Comparing the PathKeeper System for Pedicle Screw Positioning in Spine Surgery With Traditional Care
The goal of this is to evaluate performance of the Pathkeeper Surgical System. The main question[s]it aims to answer are: 1) evaluate pedicle screw position Participants will in compare Experimental arm: PathKeeper System (PKS)…
- Conditions
- Scoliosis, Scoliosis; Adolescence, Scoliosis Kyphosis, Scoliosis Lumbar Region
- Trial name
- PKSforPSP (NCT06554093)
- Testing
- Medical Device - PKS
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Deep Health Ltd.
Osteoporosis
Effects of Jumping on Growing Bones
In this study we will investigate the effects of a high-impact exercise program involving jumping on bone mass (the amount of bone) of the hip and backbone in the growing skeleton.
- Trial name
- NCT00000405
- Testing
- Exercise intervention
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Oregon State University
Intubation, Cardiac Arrest
ETI During Spinal Trauma
The aim of this study was to compare time, success rates of different tracheal tubes (standard tube and ETView VivaSight SL) for intubation with an immobilized cervical spine in a standardized manikin model.
- Trial name
- NCT02295631
- Testing
- Standard tracheal tube, ETView VivaSight SL
- Where
- Poland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- International Institute of Rescue Research and Education
Lumbar Spinal Stenosis, Lumbar Spine Instability
Ultrasound-guided ESP Block vs. Wound Infiltration in Lumbar Surgery: A Comparative Analysis (ESP:Erector Spinae Plane)
This study aimed to compare the efficacy of ultrasound-guided erector spinae plane block (ESPB) with that of wound infiltration (WI) for postoperative analgesia in lumbar spinal surgeries involving instrumentation.
- Conditions
- Lumbar Spinal Stenosis, Lumbar Spine Instability, Lumbar Spine Degeneration
- Trial name
- ESP (NCT06567964)
- Testing
- Erector Spinae Plane Block(ESPB), Wound infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Degenerative Disease, Fracture
Early Mobilisation in the Surgical Robot Assisted Spinal Surgery
In this study, patients who underwent lumbar spine surgery in our hospital were included. A prospective study was conducted to investigate the effects of early mobilisation on postoperative complications, functual outcomes and…
- Trial name
- NCT04133103
- Testing
- first ambulation at 4 hour after operation
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Beijing Jishuitan Hospital