Clinical trials: Spine
Postoperative Pain, Erector Spinae Plane Block in Spinal Surgery
Open Technique Erector Spinae Plane Block in Spinal Surgery
Erector spinae plane (ESP) block is an interfacial plane block with visceral and somatic analgesic activity at paraspinal muscles.ESPB has been successfully applied as a part of multimodal analgesia in treating postoperative pain…
- Trial name
- NCT06157762
- Testing
- Erector spinae plane block, Erector spinae plane block performed by surgeon
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Pedicle Screw, CPS
Accuracy And Safety of Trans Pedicular Screw Fixation of The Sub-axial Cervical Spine Using A Triad- Dependent Technique
The use of the pedicle screw system has become increasingly popular for treating an unstable cervical spine resulting from traumatic, degenerative, inflammatory, and neoplastic conditions.
- Trial name
- NCT05855642
- Volunteers
- 20 people
- Sponsor
- Assiut University
Orthopedic Disorder of Spine
PKP Assisted With MR Technology in OVCF With IVC
To prospectively assess the outcome of PKP assisted with and without MR technology in treatment of OVCF with IVC.
- Trial name
- NCT03959059
- Testing
- Mixed Reality technology
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Neck, Shoulder and Arm Syndrome
Neck-shoulder Pain. Large Scale Prospective Cohort Study
The aim of this study is to determine and statistically justify the correlation between shoulder girdle injuries and the development of neck-shoulder pain syndrome.
- Trial name
- NSP (NCT04366570)
- Testing
- clinical assessment of the shoulder and the cervical spine includes stress guideline tests
- Volunteers
- 1,402 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Fibromyalgia
Manipulative and Massage Therapy in the Lower Thoracic and Cervical Spine in Subjects With Fibromyalgia Syndrome
Objective: Compare degree of improvement can reach patients diagnosed with fibromyalgia syndrome, by treatment with Manipulative and Massage Techniques versus an exercise program for lower thoracic and cervical spine.
- Trial name
- NCT02864524
- Testing
- Manipulative and Massage Therapy, Exercise Program
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- Universidad de Almeria
Musculoskeletal Pain, TMJ Pain
Association of Jaw Dysfunction With Neck Disability in Subjects With Chronic Cervical Spine Disorders
Since TMJ and cervical pain incidence are rising and both structures are highly interrelated anatomically and functionally. And yet no standard protocol for TMD therapy The objective of this study is to state if there is a…
- Conditions
- Musculoskeletal Pain, TMJ Pain, Cervical Pain
- Trial name
- NCT04849442
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Horus University
Posterior Spine Surgery
Evaluation of Spine Surgery Analgesic Pathway
Investigators plan to study the role of spine surgery analgesic pathways - for procedures with high risk of postoperative pain - in improving the quality of recovery
- Trial name
- NCT02887404
- Testing
- Spine surgery analgesic pathway, Usual Care
- Where
- United States
- Volunteers
- 299 people
- Sponsor
- The Cleveland Clinic
Scoliosis
Shilla Growth Permitting Spinal Instrumentation System for Treatment of Scoliosis in the Immature Spine
The objective of this study is to retrospectively and prospectively review patients who have undergone this technique looking at age of the patient, magnitude of the curve preoperatively, postoperatively and over time, diagnosis…
- Trial name
- NCT00577226
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Arkansas Children's Hospital Research Institute
Facet Joint Pain, Facet Syndrome of Lumbar Spine
Injections in the Diagnosis and Treatment of Lumbar Facet Syndrome
In suspected facet joints pain, it is recommended to perform nerve blocks to establish the diagnosis with positive results being and indicator of successful of most permanent treatment of facet pain by rhizolysis.
- Conditions
- Facet Joint Pain, Facet Syndrome of Lumbar Spine, Facet Joints; Degeneration
- Trial name
- NCT03871192
- Testing
- FACET JOINT UNDER CT GUIDANCE, NERVE BLOCK UNDER CT GUIDANCE, FACET JOINT UNDER FLUOROSCOPY GUIDANCE
- Where
- 2 sites in Spain
- Volunteers
- 100 people
- Sponsor
- Complejo Hospitalario Universitario de Granada
Degenerative Spine Disease, Spondylolisthesis
MIS ReFRESH: Robotic vs. Freehand Minimally Invasive Spinal Surgeries
To quantify potential short- and long-term benefits of robotically-guided minimally invasive spine surgery (MIS) for adult patients with lower back degeneration, in comparison a matching group of control patients operated in a…
- Conditions
- Degenerative Spine Disease, Spondylolisthesis, Spondylosis
- Trial name
- NCT02057744
- Where
- 9 sites in United States
- Volunteers
- 600 people
- Sponsor
- Mazor Robotics
Spine Surgeries
Thoracolumber Oterfacial Plane Block for Spine Surgery
The most commonly used technique to anesthetize patients scheduled for thoracic or lumbar spine surgery is general anesthesia. Analgesic techniques vary from the use of neuraxial techniques like epidural, intrathecal, or caudal…
- Trial name
- TLIP (NCT03060681)
- Testing
- Bupivacaine 0.5% injected in the thoraco-lumber inetrfacial plane block
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Spine Surgery
Radiological and Clinical Efficacy of a Hybrid Spinal Implant ("Topping Off"): a Mono-center, Prospective Clinical Trial
The study aim is to show the effectiveness of a hybrid system (DTO) regarding clinical outcome and radiological alteration in a single-center prospective setting.
- Trial name
- NCT03404232
- Testing
- Dynesys DTO device (Zimmer Spine, Inc.)
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University Hospital, Aachen
Multiple Sclerosis, Muscle Spasticity
Effect of Cervical Mobilization on Balance and Plantar Pressure Distribution in Multiple Sclerosis
MS patients were randomly divided into traditional therapy and traditional therapy + cervical mobilization groups. While muscle strengthening, stretching, balance and coordination exercises were given to the traditional group…
- Conditions
- Multiple Sclerosis, Muscle Spasticity, Pressure Area, Cervical Region Disorder Nos
- Trial name
- NCT04543448
- Testing
- Traditional Rehabilitation for multiple sclerosis, Cervical mobilization for multiple sclerosis
- Where
- Turkey (Türkiye)
- Volunteers
- 12 people
- Sponsor
- Hasan Kalyoncu University
Bone Tumor, Osteoporosis
U.S. Prospective Evaluation of EPIONE Device for Percutaneous MSK Procedures
The goal of this investigational device exemption is to evaluate the Epione assistance for introducer placement during percutaneous procedures in musculo-skeletic (MSK) structures of the pelvis and the spine in adults.
- Conditions
- Bone Tumor, Osteoporosis, Traumatic Fracture
- Trial name
- EPIOS (NCT07325578)
- Testing
- Percutaneous procedure in the MSK structures of the pelvis and/or the spine
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- Precision IO Group
Cerebral Hypoxia During and/or Resulting From A Procedure
The Effects of Body Mass İndex On İntraabdominal Pressure And Regional Cerebral Oxygen Saturation İn Prone Position
A total of 40 ASA (American Society of Anesthesiology) physical status I-III who underwent lumbar disc hernia repair for one or two levels were included in this prospective study.
- Trial name
- NCT05392478
- Volunteers
- 40 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Spine Surgery With Neuromonitoring
Water Homeostasis in Propofol Based Total Intravenous Anesthesia
Previous study reported that propofol binded to glutamate receptors in the hypothalamus and inhibits AVP release mediated by endogenous γ-aminobutyric acid, as well as directly inhibits the regulated calcium currents leading to…
- Trial name
- NCT04058106
- Testing
- A patient who need the cerebral artery aneurysm clipping surgery
- Where
- South Korea
- Sponsor
- Gangnam Severance Hospital
Spine Fracture
Percutaneous Kyphoplasty Using Rotary Cutter in Osteoporotic Vertebral Fractures
Kyphoplasty(PKP) is performed under general anaesthesia in patients with osteoporotic vertebral compression fracture. The balloon is first placed into the fractured vertebra and inflated with contrast agent for height…
- Trial name
- NCT03850938
- Testing
- Conventional Kyphoplasty, Kyphoplasty with Rotary Cutter
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Li Min
Cervical Spondylosis, Lumbar Spondylosis
Safety and Efficacy of Pre-incisional Intravenous Ibuprofen to Reduce Postoperative Pain and Opioid Dependence After Posterior Cervical or Lumbar Instrumented Spine Surgery
A prospective, randomized, placebo controlled, double-blinded study at a single institution.
- Trial name
- NCT02276911
- Testing
- Ibuprofen, normal saline
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- St. Joseph's Hospital and Medical Center, Phoenix
Osteoporosis
Transition From Alendronate to Romosozumab (AMG 785)
The purpose of this study is to estimate the percent change from baseline in lumbar spine bone mineral density (BMD) following multiple-dose administrations of romosozumab in postmenopausal women with low BMD previously treated…
- Trial name
- NCT01588509
- Testing
- Romosozumab
- Where
- 9 sites in United States
- Volunteers
- 60 people
- Sponsor
- Amgen
Cervical Pedicle Screw
Analysis of Sub Axial Cervical Pedicle Spine Based on CT
The aim of study to analyze morphometry of sub axial cervical spine pedicle in an Egyptian population based on computed tomography (CT) and thus asses the safety and feasibility of cervical pedicle screw in the sub axial cervical…
- Trial name
- NCT06445348
- Testing
- Cervical pedicle screw
- Volunteers
- 80 people
- Sponsor
- Assiut University