Clinical trials: Spinal Surgery
Return of Bowel Function Following Spinal Surgery
Does Chewing Gum Hasten Return of Bowel Function Post-Operatively in Patients Undergoing Spinal Surgery
The specific aim of this prospective, randomized controlled trial is to compare the effect of chewing gum on the return of bowel function in a group of patients undergoing spinal surgery with a group of matched controls that do…
- Trial name
- NCT02186717
- Testing
- Chewing gum
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Hospital for Special Surgery, New York
Total Knee Arthroplasty
Minimal Sedation During Knee Replacement Surgery
This study will test the use of active noise cancelling headphones with music or a movie during knee replacement surgery. Feedback from the surgical team and from patients regarding the headset system will be gathered to see if…
- Trial name
- NCT07371390
- Testing
- Active Noise Cancelling Headset System
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Mayo Clinic
Total Hip Replacement
Hemodynamic Effect of Lumbosacral Plexus Blockade Versus Spinal Anesthesia
The study evaluates the hemodynamic effect of lumbosacral plexus blockades versus spinal anesthesia for hip replacement. Half of participants will receive lumbosacral plexus blockade and the other half will receive continuous…
- Trial name
- NCT02544269
- Testing
- Ropivacaine, Bupivacaine
- Where
- Denmark
- Volunteers
- 8 people
- Sponsor
- University of Aarhus
Pain, Postoperative
Analgesic Efficacy of Repeated Doses of Intravenous (IV) Acetaminophen in Post-operative Pediatric Spine Fusion Patients
This is a prospective, randomized, double-blinded, placebo controlled trial Potential subjects will be identified from the Pre-Surgical Anesthesia Clinic visit.
- Trial name
- IV APAP SF (NCT01394718)
- Testing
- Intravenous Acetaminophen
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Children's Hospital of Philadelphia
Spinal Stenosis, Intervertebral Disc Displacement
Tranexamic Acid in Reducing Gross Hemorrhage and Transfusions of Spine Surgeries
Multilevel decompression and bone graft fusion is a most effective measure for treating degenerative lumbar spinal diseases. Yet, the surgery is commonly associated with large amount of perioperative blood loss and high demand…
- Trial name
- TARGETS (NCT03011866)
- Testing
- Wound topically irrigated with 500mg TXA, 1mg/kg/hr TXA intravenous infusion till the last suture
- Volunteers
- 176 people
- Sponsor
- Peking Union Medical College Hospital
Regional Anaesthesia, Anesthesia and Analgesia
Comparison of the Efficacy of Celiac Plexus Blockade, ESP and Lidocaine Infusion Under OFA
Modern anesthesiology, in search of alternatives to opioid-based pain management, is turning to low-opioid and non-opioid protocols.
- Trial name
- LECO (NCT06793527)
- Testing
- Celiac Plexus Block, ESP block, Lidacaine
- Where
- Poland
- Volunteers
- 300 people
- Sponsor
- Jagiellonian University
Spinal Diseases
The Effect of Perioperative Lidocaine Intravenous Infusion on Postoperative Recovery After Spine Surgery.
The purpose of this study is to evaluate the effectiveness of perioperative Lidocaine intravenous infusion in reducing postoperative pain for spine surgery patients.
- Trial name
- NCT02762656
- Testing
- Lidocaine
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Lumbar Disc Herniation
The Effect of Progressive Relaxation Exercise on Pain and Kinesiophobia After Lumbar Disc Herniation Surgery
We aimed to assess the influence of progressive muscle relaxation exercise on kinesiophobia and pain during after lumbar disc surgery using the Visual Analog Scale (VAS) and the Tampa Kinesiophobia Scale in a prospective…
- Trial name
- NCT05288634
- Testing
- Progressive relaxation exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Aksaray University
Hip Fractures
Pericapsular Nerve Group Block Versus Femoral Nerve Block Study
Hip fractures are common in older adults and are often associated with severe pain, making it difficult for patients to sit for spinal anesthesia before surgery.
- Trial name
- NCT07717463
- Testing
- Ultrasound-Guided Pericapsular Nerve Group (PENG) Block, Ultrasound-Guided Femoral Nerve Block, Spinal Anesthesia (bupivacaine)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Taksim Egitim ve Arastirma Hastanesi
Post-Dural Puncture Headache
Trans-nasal Sphenopalatine Ganglion Block Versus Ultrasound-guided Bilateral Greater and Lesser Occipital Nerve Block for Management of Post-Dural Puncture Headache.
Post-Dural Puncture Headache (PDPH) is a complication associated with spinal anesthesia. While conventional treatments are available, the Epidural Blood Patch (EBP) is considered the gold standard.
- Trial name
- TNSPGB /GALONB (NCT06705244)
- Testing
- Trans-nasal sphenopalatine nerve block, Greater and lesser occipital nerve block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Operation
Spinal Anesthesia Magnesium Infusion
The aim of this study was to investigate the effect of i.v. infusion of magnesium sulphate during spinal anesthesia on duration of spinal block and postoperative pain.
- Trial name
- NCT02011152
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Pregnant Women, Enhanced Recovery After Surgery (ERAS) Protocol
ERAS Protocol on Maternal and Fetal Outcomes Following Elective Cesarean Section
The goal of this observational study is to investigate the maternal, fetal, and neonatal outcomes in parturients scheduled to undergo elective cesarean section (CS) receiving either standard care or enhanced recovery after…
- Trial name
- ERAS (NCT06753058)
- Testing
- 25 gram of maltodextrin in 330 mL , Nutricia Fantomalt 4 Gram, Nutri Gıda Ürünleri San. ve Tic. A.Ş., Istanbul, Türkiye, 2 h prior to surgery., Mother baby bonding
- Where
- Turkey (Türkiye)
- Volunteers
- 450 people
- Sponsor
- Gazi University
Lumbar Disc Herniation
Comparison Between Conventional vs. Endoscopic Lumbar Discectomy
This study is aimed to compare between the results of conventional lumbar discectomy and the newly used technique in our department; endoscopic lumbar discectomy in neurosurgery department Assiut university hospitals, so that we…
- Trial name
- NCT03137485
- Testing
- Conventional open lumbar discectomy, Percutaneous Endoscopic Translaminar lumbar discectomy., Easy Go system Endoscopy
- Volunteers
- 30 people
- Sponsor
- Assiut University
Spinal Fusion
Artoss Prospective Spine Registry Outcomes
This prospective registry was designed as an observational study to ascertain how commercially available NanoBone Bone Graft is being used by surgeons performing spinal fusion as well as determining relevant patient outcomes.
- Trial name
- ASTRO (NCT04439032)
- Testing
- NanoBone Bone Graft Substitute
- Where
- 6 sites in United States
- Volunteers
- 330 people
- Sponsor
- Artoss Inc.
Surgery Requiring Spinal Anesthesia
Validation of Phase Lag Entropy(PLE) as an Indicator of Depth of Sedation in Patients Undergoing Spinal Anesthesia
For verifying the phase lag entropy as the tool for measurement of level of consciousness, the investigators compared phase lag entropy to bispectral index.
- Trial name
- NCT03319004
- Testing
- apply phase lag entropy sensor
- Where
- South Korea
- Volunteers
- 27 people
- Sponsor
- Gangnam Severance Hospital
Scoliosis
Low-dose Dual-energy CT for the Pre-surgical Planning of Patients With Progression of Scoliosis
The aim of the study is to evaluate the diagnostic accuracy of low-dose dual energy CT in the pre-surgical planning of patients with progression of scoliosis
- Trial name
- NCT03483844
- Testing
- GE CT 750 HD
- Where
- Italy
- Volunteers
- 64 people
- Sponsor
- Istituto Ortopedico Rizzoli
Lumbar Spinal Stenosis
Study of Epidural Steroid Injection (ESI) Versus Minimally Invasive Lumbar Decompression (Mild®) in Patients With Symptomatic Lumbar Central Canal Stenosis
This is a single-center, randomized, prospective, double-blind clinical study to assess the clinical application and outcomes with MILD® devices versus epidural steroid injection in patients with symptomatic moderate to severe…
- Trial name
- NCT00995371
- Testing
- MILD® (Minimally Invasive Lumbar Decompression), Epidural Steroid Injection
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Coastal Orthopedics & Sports Medicine
Vertebral Subluxation, Spine Disease
Erector Spinae Block vs Morphine in Vertebral Fixation
The study aims to shed light about the potential role of Erector Spinae Block in the management of postoperative pain following vertebral fixation surgery via posterior approach.
- Conditions
- Vertebral Subluxation, Spine Disease, Spondylolisthesis
- Trial name
- ATLANTE (NCT04729049)
- Testing
- Erector Spinae plane Block, Patient controlled analgesia with intravenous morphine
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- AUSL Romagna Rimini
Post-operative Pain, Spine, Open
The Effect of Press Needle in the Combination of Ear and Body Acupuncture Points on Visual Analog Scale in Post-Operative Patients of Open Spine Surgery
Postoperative pain is pain that arises after a surgical procedure, resulting from trauma during the surgical incision process. It is generally acute in nature and is accompanied by an inflammatory response.
- Trial name
- NCT06165575
- Testing
- Press needle
- Where
- 3 sites in Indonesia
- Volunteers
- 54 people
- Sponsor
- Universitas Indonesia
Acute Post Operative Pain, Hip Fracture
Pain Relief Comparison: Pericapsular Nerve Group Versus Quadratus Lumborum Block for Positioning in Femur Fracture Surgery
This study aims to compare the analgesic efficacy of Ultrasound Guided Pericapsular Nerve Group Block and Quadratus Lumborum Block for pain relief During patient Positioning for Spinal Anesthesia in proximal femur fracture…
- Conditions
- Acute Post Operative Pain, Hip Fracture, Regional Anaesthesia, Quadratus Lumborum Block
- Trial name
- NCT06917807
- Testing
- Pericapsuler nerve group block, Quadratus lumborum block
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Ain Shams University