Clinical trials: Spinal Stenosis Lumbar
Spinal Stenosis Lumbar
Lumbar Proprioception in Patients With Lumbar Spinal Stenosis
The primary aim of this study was to compare spinal proprioception in patients with Lumbal Spinal Stenosis (LSS) (with or without surgery) and healthy controls.
- Trial name
- NCT05548608
- Testing
- Reposition error (RE), pain at target positions of RE and flexibility of the TLF were assesed with iphone tiltmeter app, VAS and goniometric platform, respectively.
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Degenerative Disc Disease, Isthmic-lytic Spondylolisthesis
Efficacy of Using Solum IV and BMC With GFC in TLIF
The purpose of this study is to examine the efficacy of using Solum IV and bone marrow concentrate with general fluid concentrate in Transforaminal Lumbar Interbody Fusion (TLIF).
- Conditions
- Degenerative Disc Disease, Isthmic-lytic Spondylolisthesis, Degenerative Spondylolisthesis, Spinal Stenosis
- Trial name
- NCT03223701
- Testing
- Solum IV, Bone Marrow Concentrate with general fluid concentrate (GFC) in Transforaminal Lumbar Interbody Fusion
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Seton Healthcare Family
Lumbar Spinal Stenosis, Cardiac Amyloidosis
Analysis of Lumbar Spine Stenosis Specimens for Identification of Transthyretin Cardiac Amyloidosis
Primary objective: To identify older adults with transthyretin cardiac amyloidosis (ATTR-CA) early in the course of the illness, at a time when disease modifying therapies are most effective.
- Conditions
- Lumbar Spinal Stenosis, Cardiac Amyloidosis, ATTR Amyloidosis Wild Type, ATTR Gene Mutation
- Trial name
- NCT06034405
- Testing
- Tc99-PYP or Tc99-HDMP Scan
- Where
- 6 sites in United States
- Volunteers
- 1,663 people, healthy volunteers welcome
- Sponsor
- Columbia University
Ankle Osteoarthritis, Knee Osteoarthritis
Gait Asymmetry Assessed Using Portable Gait Analysis System
To date, detailed analysis of movement patterns in orthopaedic conditions are mainly performed in research projects. Because these tests are time consuming, they are not feasible in clinical routine or in standard examinations.
- Conditions
- Ankle Osteoarthritis, Knee Osteoarthritis, Hip Osteoarthritis, Lumbar Spine Stenosis
- Trial name
- Asymmetry (NCT02489188)
- Testing
- arthroplasty, manual therapy, lumbar spinal stenosis decompression
- Where
- Switzerland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Degenerative Lumbar Canal Stenosis
Comparison Between The Results of Open and Microsurgical Decompression in Degenerative Spinal Canal Stenosis in Lumbar Spine
To compare the outcomes of open and microsururgical decompression in degenerative spinal stenosis in lumbar spine
- Trial name
- NCT06722859
- Testing
- Open surgical decompression in degenerative lumbar canal stenosis, Microsurgical decompression
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Assiut University
Lumbar Disc Herniation, Lumbar Discogenic Pain
Comparing General Anesthesia, General Anesthesia With ESP Block or TLIP Block in Patients Undergoing Lumbar Surgeries
The regional methods of anesthesia for the neurosurgical operations of the spine and spinal cord reducing the needs for opioids intra operatively and reducing pain in the postoperative period, decrease the numbers of failed back…
- Conditions
- Lumbar Disc Herniation, Lumbar Discogenic Pain, Lumbar Spinal Stenosis, Failed Back Surgery Syndrome
- Trial name
- NCT05447780
- Testing
- regional anesthesia
- Where
- Ukraine
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Anesthesia Research Group UA
Low Back Pain, Lumbosacral Radiculopathy
A Prospective Study to Compare Bupivacaine and Exparel Versus Bupivacaine or Exparel Alone for Postoperative Pain Relief
The purpose of this study is to collect information about how patients feel when doctors manage their pain after lumbar spine surgery using a combination of EXPAREL® and bupivacaine injected into the lumbar spine at the end of…
- Conditions
- Low Back Pain, Lumbosacral Radiculopathy, Lumbar Disc Degeneration, Lumbar Disc Herniation
- Trial name
- NCT03514277
- Testing
- Exparel, Bupivacaine
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Virtua Health, Inc.
Lumbar Spinal Stenosis
Predictors of Decompressive Laminectomy Outcomes
Decompressive laminectomy (DL) is the most common type of back surgery performed in older adults; DL treats lumbar spinal stenosis (LSS), a degenerative narrowing of the spinal canal causes pain and trouble walking.
- Trial name
- NCT02215551
- Where
- 7 sites in United States
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Degenerative Disc Disease Lumbar, Spinal Stenosis
Multimodal Analgesia Versus Routine Care Pain Management
Most patients undergoing surgery experience significant post-operative pain. Inadequate peri-operative pain management may decrease post-operative mobilization and increase length of hospitalization.
- Conditions
- Degenerative Disc Disease Lumbar, Spinal Stenosis, Lumbar Spondylolisthesis
- Trial name
- MMA (NCT01861743)
- Testing
- Multimodal Analgesia, Patient controlled analgesia
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Nasal Obstruction, Lumbar Stenosis, Familial
Comparison of Intubation Conditions Between the Gliderite and the S-Guide
Intubation with an unchanneled videolaryngoscope mandates the use of a stylet. The Gliderite is a stylet specially designed for videolaryngoscopes.
- Trial name
- S-Guide (NCT02519647)
- Testing
- Tracheal intubation with Gliderite, Tracheal intubation with S-guide
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Spinal Stenosis Lumbar, Disc Degeneration
Efficacy and Safety of Preemptive Intravenous Dexamethasone in MIS-TLIF
Researchers are considering Dexamethasone as preemptive medication before minimally invasive spine fusion surgery to minimize postoperative back pain with minimal side effects, aiming to enhance the effectiveness of surgery and…
- Conditions
- Spinal Stenosis Lumbar, Disc Degeneration, Disc Disease, Fusion of Spine
- Trial name
- MIS-TLIF (NCT06367855)
- Testing
- Dexamethasone, Normal saline
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Potsawat Surabotsopon
Spondylosis, Spondylolisthesis
Return of Bowel Function After One or Two Level Anterior Lumbar Interbody Fusion With Chewing Gum
Researchers are trying to identify is chewing gum improves bowel function after anterior lumbar interbody fusion
- Conditions
- Spondylosis, Spondylolisthesis, Neurogenic Claudication, Foraminal Stenosis
- Trial name
- NCT03945461
- Testing
- Chewing gum
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Lumbar Spinal Stenosis, Lumbar Spine Instability
Ultrasound-guided ESP Block vs. Wound Infiltration in Lumbar Surgery: A Comparative Analysis (ESP:Erector Spinae Plane)
This study aimed to compare the efficacy of ultrasound-guided erector spinae plane block (ESPB) with that of wound infiltration (WI) for postoperative analgesia in lumbar spinal surgeries involving instrumentation.
- Conditions
- Lumbar Spinal Stenosis, Lumbar Spine Instability, Lumbar Spine Degeneration
- Trial name
- ESP (NCT06567964)
- Testing
- Erector Spinae Plane Block(ESPB), Wound infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Lumbar Spinal Stenosis
Gait Assessment in Lumbar Spinal Stenosis
Lumbar spinal stenosis (LSS) is a clinical condition in which the structures within the canal are compressed as a result of the narrowing of the lumbar spinal canal and nerve root canals, which is often caused by bones and soft…
- Trial name
- NCT06750055
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Lumbar Spinal Stenosis
Patients With Lumbar Spinal Stenosis With Balance Disorder
It is seen that patients with Lumbar Spinal Stenosis often experience balance problems. Although the relationship between muscle thickness and balance has been explained, there are insufficient studies investigating the…
- Trial name
- NCT06079580
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Spinal Stenosis, Lumbar Region With Neurogenic Claudication
Assessing Superion Clinical Endpoints vs. Decompression
PURPOSE: The primary purpose of this study is to demonstrate that the Composite Clinical Success of the study group receiving the Superion® IDS is not inferior to the success rate observed in the study group treated by direct…
- Trial name
- ASCEND (NCT03048955)
- Testing
- Superion® IDS, Direct decompression Surgery
- Where
- 5 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- VertiFlex, Incorporated
Degenerative Lumbar Spinal Stenosis, Degenerative Disc Disease
Effect of RECK in Posterior Spinal Fusion
"RECK" is a combination of local anesthesia medications, used for the purpose of pain control. RECK is an acronym which stands for Ropivacaine, Epinephrine, Clonidine, and Ketorolac.
- Conditions
- Degenerative Lumbar Spinal Stenosis, Degenerative Disc Disease, Degenerative Spondylolisthesis, Degenerative Disease
- Trial name
- NCT06447194
- Testing
- Ropivacaine, Epinephrine, Clonidine, and Ketorolac Injection Cocktail
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Spinal Stenosis Lumbar, Surgical Site Infection
Efficacy of ActiveMatrix on Spinal SSI Rate
This clinical trial seeks to provide high level of evidence on the efficacy of ActiveMatrix primarily on spinal surgical site infection rate.
- Conditions
- Spinal Stenosis Lumbar, Surgical Site Infection, Back Pain Lower Back Chronic
- Trial name
- NCT05297513
- Testing
- ActiveMatrix
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Degenerative Disc Disease, Spondylolisthesis
Prospective, Multi-center Study to Assess Posterolateral Fusion Using FIBERGRAFT
This is a prospective, non-randomized (single arm), multi-center, post-market clinical study designed to evaluate FIBERGRAFT® BG Matrix mixed with autograft and bone marrow aspirate in up to 150 subjects with degenerative disc…
- Conditions
- Degenerative Disc Disease, Spondylolisthesis, Spinal Stenosis Lumbar
- Trial name
- NCT03884283
- Testing
- FIBERGRAFT BG Matrix
- Where
- 9 sites in United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Prosidyan, Inc.
Spinal Stenosis Lumbar
Effects and Safety of Epidural PDRN vs. Placebo
This is a single-center, randomized, double-blind clinical study to assess the clinical application and outcomes with epidural PDRN versus Normal saline injection in patients with spinal stenosis.
- Trial name
- NCT04401735
- Testing
- Polydeoxyribonucleotides, Normal saline
- Where
- South Korea
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital