Clinical trials: Spinal Pain
Pain, Postoperative
Spinal Morphine for Postoperative Analgesia in Urology
The study was performed in urology patients elicited for open prostatectomy or open nephrectomy. Comparison of analgesic effect between group (M) with spinal morphine before general anaesthesia and group without this intervention…
- Trial name
- NCT03675646
- Testing
- Morphine
- Where
- Czechia
- Volunteers
- 98 people
- Sponsor
- Charles University, Czech Republic
Brachytherapy
Valsalva Maneuver and Control in Reducing Pain During Spinal Injection
The study aimed to compare the effectiveness of Valsalva maneuver as non pharmacological approach and control in reducing pain during spinal injection.
- Trial name
- NCT04215276
- Testing
- Valsalva maneuver, Control
- Where
- Indonesia
- Volunteers
- 70 people
- Sponsor
- Universitas Indonesia
The Lumbar Spine Surgical Intervention, Arthrodesis
Evaluation of the Effect of Reiki on Pain After Lumbar Surgery
The goal of this clinical trial (prospective, comparative, and randomized double-blind study) is to learn if Reiki (a non-pharmacological intervention), when used alongside standard care, can treat and reduce postoperative pain…
- Conditions
- The Lumbar Spine Surgical Intervention, Arthrodesis, Severe Herniated Disc, Scoliosis
- Trial name
- REDAL (NCT07722117)
- Testing
- Reiki treatment and chirurgy
- Where
- 2 sites in France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Clinique Bizet
Lumbar Spine Disease
Effectiveness of Home Programs After Lumbar Spinal Decompression Surgery
The study will be conducted with volunteer patients who are followed up by Bursa Çekirge State Hospital Cekirge State Hospital Neurosurgery outpatient clinic and who have undergone lumbar decompression surgery and who meet the…
- Trial name
- NCT06014645
- Testing
- Rehabilitation, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Muğla Sıtkı Koçman University
Neck Pain, Manipulation, Spinal
3-D Laser Imaging to Analyze Neck Movement
The goal of this research project is to develop a new system that uses lasers to provide 3-dimensional (3-D) images of the cervical spine (the seven spinal bones in the neck) in a moving person.
- Trial name
- NCT00022828
- Testing
- 3-D Laser Imaging Device
- Where
- 2 sites in United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Spinal Cord Injuries
Brivaracetam to Reduce Neuropathic Pain in Chronic Spinal Cord Injury
Spinal cord injury (SCI) is associated with severe neuropathic pain that is often refractory to all pharmacological intervention.
- Trial name
- NCT04379011
- Testing
- Brivaracetam
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- University of Minnesota
Lumbar Spinal Fusion
Efficacy of TLIP Block for Postoperative Analgesia of Lumbar Spinal Fusion
Spinal surgery is associated with severe pain in the immediate postoperative period. In a recent study evaluating pain intensity on the first day after surgery in a large range of surgical procedures, among the six most painful…
- Trial name
- ETLA (NCT04593953)
- Testing
- TLIP
- Where
- 2 sites in France
- Volunteers
- 94 people
- Sponsor
- CMC Ambroise Paré
Juvenile; Scoliosis, Scoliosis Idiopathic
Studying Melatonin and Recovery in Teens
The goal of this feasibility clinical trial is to learn if melatonin can help teens having major musculoskeletal surgery by promoting healthy sleep.
- Conditions
- Juvenile; Scoliosis, Scoliosis Idiopathic, Scoliosis; Adolescence, Scoliosis;Congenital
- Trial name
- SurgerySMART (NCT06093477)
- Testing
- Fast-Dissolve Melatonin Pill
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Stanford University
Rheumatoid Arthritis, Ankylosing Spondylitis
Assessment of Pain Management in Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis Patients Who Are About to be Treated With Adalimumab
The purpose of this study is to assess whether or not adalimumab (Humira®) can influence pain medication in participants with rheumatoid arthritis (RA), psoriatic arthritis (PsA) and ankylosing spondylitis (AS) with or without…
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Psoriatic Arthritis
- Trial name
- NCT01273519
- Where
- 15 sites in Austria
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- AbbVie (prior sponsor, Abbott)
Neck Pain, Spondylosis
CEM-Plate and CEM-Cage First-In-Human Use Efficacy Study
The study is a prospective, first-in-human, multi-center, non-randomized, single-arm study to assess the safety and efficacy of the CEM-Cage used with the CEM-Plate in patients who are appropriate candidates for a 2-level…
- Conditions
- Neck Pain, Spondylosis, Spondylosis With Myelopathy, Spondylosis With Radiculopathy
- Trial name
- NCT04883411
- Testing
- CEM-Plate Anterior Cervical Plating System and CEM-Cage Cervical Interbody System
- Where
- 4 sites in United States
- Volunteers
- 50 people
- Sponsor
- ReVivo Medical, Corp.
Labor Pain
CSE for Labour Analgesia: A Comparison of Two Intrathecal Regimens
Analgesia in labour is not readily available in many parts of Sub-Saharan Africa. The overall cost of Epidural services in terms of human personnel and financial implication makes this inaccessible to many women in labour.
- Trial name
- SSS (NCT03117595)
- Testing
- Bupivacaine-fentanyl, Bupivacaine-fentanyl morphine
- Where
- Nigeria
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sarah Beckley
Anesthesia, Pain
Lidocaine Compared to Magnesium Sulfate to Prolong Spinal Anesthesia: Non-inferiority Randomized Clinical Trial
This study evaluates the addition of continuous infusion of lidocaine or continuous infusion of magnesium sufate in the duration of spinal anesthesia.
- Trial name
- NCT03725228
- Testing
- Magnesium Sulfate, Lidocaine
- Where
- Brazil
- Volunteers
- 44 people
- Sponsor
- Brasilia University Hospital
Spinal Cord Injury + Peripheral Nerve Diseases
Assessment of Neuropathic Pain
Development of neuropathic pain is one of the most disabling sequels after spinal cord injury (SCI) and in peripheral nerve diseases.
- Trial name
- NCT02138344
- Where
- Switzerland
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Low Back Pain
Specific or Non-Specific Manipulation for Patients With Back Pain
We aim to evaluate the long-term effects of 10 sessions of spinal manipulative therapy applied in a vertebral region-specific or region nonspecific level immediately after treatment and 3 and 6 months after randomization.
- Trial name
- NCT02883634
- Testing
- Specific manipulation, Non-specific manipulation
- Where
- Brazil
- Volunteers
- 148 people
- Sponsor
- Universidade Cidade de Sao Paulo
Postoperative Pain
Effect of TAP Block on Time Required for First Analgesic Dose After Cesarean Cection Under Spinal Anesthesia
While opioids are the mainstay for post-operative analgesia after caesarean section, they are associated with various side effects.
- Trial name
- NCT04623632
- Testing
- Transversus abdominus plane block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams Maternity Hospital
Central Neuropathic Pain, Allodynia
Clinical Neuropharmacology of Pain in Spinal Cord Injury- Dextromethorphan Dose Response Clinical Trial
This randomized, placebo-controlled, double-blind 4x4 crossover clinical trial was part of a larger NIH-funded study to evaluate the analgesic efficacy of three doses of chronic oral (PO) dextromethorphan compared to placebo in…
- Conditions
- Central Neuropathic Pain, Allodynia, Spinal Cord Injury
- Trial name
- NCT01435798
- Testing
- Dextromethorphan
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Brigham and Women's Hospital
Non-specific Low Back Pain
The Effect of Combining Spinal Manipulation and Dry Needling in Individuals With Low Back Pain
The goal of this study is to enroll and randomize 99 participants with non-specific low back pain into a multimodal strategy of treatment consisting of a combination of dry needling (DN) and spinal manipulation therapy (SMT), DN…
- Trial name
- SMTDNLBP (NCT05802901)
- Testing
- Spinal manipulation, Dry needling, Spinal manipulation and dry needling
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- University of Utah
Osteo Arthritis Knee and Hip, Osteo Arthritis
General Anaesthesia vs Spinal Anaesthesia: Patient Outcomes and Success in Outpatient Primary Total Knee and Hip Arthroplasty
Total knee arthroplasty (TKA) and total hip arthroplasty (THA) are common operations used to treat severe joint disease, most often caused by osteoarthritis.
- Conditions
- Osteo Arthritis Knee and Hip, Osteo Arthritis, Inflammatory Joint Disease (IJD)
- Trial name
- GASPS (NCT07334132)
- Testing
- General Anaesthesia, Spinal Anesthesia (bupivacaine)
- Volunteers
- 600 people
- Sponsor
- Region Örebro County
Opioid Consumption, Postoperative, Pain, Postoperative
Comparison of Pain Relief Methods for Hip Surgery: A Study on Two Different Nerve Block Techniques
This prospective randomized comparative study aims to compare the analgesic efficacy of pericapsular nerve group block (PENG) and lumbar erector spinae plane block (L-ESP) groups to relieve postoperative pain in participants over…
- Conditions
- Opioid Consumption, Postoperative, Pain, Postoperative, Nerve Block, PENG Block
- Trial name
- NCT06821516
- Testing
- Evaluation of the postoperative analgesic effectiveness of PENG block in participants undergoing total hip arthroplasty under spinal anesthesia, Evaluation of the postoperative analgesic effectiveness of lumbar erector spinae block in participants undergoing total hip arthroplasty under spinal anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Lower Back Pain
A Clinical Study of the GO-LIF® Approach for Lumbar Spinal Fixation
The purpose of this study is to collect data regarding the safety and feasibility of the GO-LIF procedure for spinal fixation and stabilization, in conjunction with conventional approaches for interbody lumbar fusion.
- Trial name
- NCT00810433
- Testing
- GO-LIF - Guided Oblique Lumbar Interbody Fusion
- Where
- 10 sites in Germany, Israel
- Volunteers
- 10 people
- Sponsor
- Mazor Robotics