Clinical trials: Spinal Injury
Perinatal Spinal Cord Injury
Understanding Perinatal Spinal Cord Injury
The purpose of this study is to deepen our understanding of children who have a cervical spinal cord injury obtained in utero or at birth and examine the effects of tailored activity-based recovery training (ABRT) in combination…
- Trial name
- NCT06808035
- Testing
- Activity-Based Recovery Training, Transcutaneous Spinal Cord Stimulation
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Louisville
Spinal Cord Injury
The ATLET Study: Can Subjects With Incomplete Spinal Cord Injury Learn to Walk?
The ATLET study will assess the effect of manual or robotic body-weight supported locomotor training of patients with stable motor incomplete spinal cord injury (SCI) on gait and overall ADL function as well as on estimated…
- Trial name
- ATLET (NCT00854555)
- Testing
- Locomotor training with robot, Locomotor training with manual assistance
- Where
- 2 sites in Norway
- Volunteers
- 44 people
- Sponsor
- North Norway Rehabilitation Center
Spinal Cord Injury, Peer Group
A Patient-centered Approach to Successful Community Transition After Catastrophic Injury
Shepherd Center is bringing a more patient-centered focus to educational, peer-support, and technology resources offered to patients with spinal cord injury and their families and is evaluating these changes.
- Trial name
- NCT02746978
- Testing
- Peer directed education, Patient Engagement Portal
- Volunteers
- 800 people
- Sponsor
- Shepherd Center, Atlanta GA
Spinal Cord Injuries
Sensorimotor Integration Underlying Balance Control in Individuals With Incomplete Spinal Cord Injury
The objectives of the study are to evaluate a 4-week mixed training paradigm consisting of explosive strength training and balance perturbation training efficacy on balance control during standing and locomotion, and to…
- Trial name
- NCT05200091
- Testing
- Combined explosive strength and specific balance training group
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Centre for Interdisciplinary Research in Rehabilitation of Greater Montreal
Locked-in Syndrome, Neuromuscular Diseases
Investigation on the Cortical Communication System
The goal of this clinical trial is to demonstrate communication through a brain implant in people in locked-in state, i.e. people with severe paralysis and communication problems.
- Conditions
- Locked-in Syndrome, Neuromuscular Diseases, Brainstem Stroke, Traumatic Brain Injury
- Trial name
- CortiCom (NCT06207591)
- Testing
- ECoG (electrocorticography) sensing
- Where
- Netherlands
- Volunteers
- 2 people
- Sponsor
- UMC Utrecht
Cesarean Section
Dexmedetomidine Versus Magnesium Sulphate for Caesarean Delivery
Regional anesthesia has become more popular in cesarean deliveries because most of the parturients prefer being awake during the birth process. In addition, regional anesthesia may be a safer method than general.
- Trial name
- NCT03067896
- Testing
- Bupivacaine, Dexmedetomidine, Magnesium Sulfate
- Where
- Egypt
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Assiut University
Spinal Cord Injuries
FES Cycling and Nutritional Counseling for Battling Obesity After SCI
Individuals who suffer from paralysis after spinal cord injury (SCI) are estimated to have an even greater (66%) prevalence of obesity.
- Trial name
- NCT03810963
- Testing
- HIIT-FES Cycling combined with Nutritional Counseling, Nutritional Counseling Only
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- William Carey University
Spinal Injuries
Telemonitored Exercise to Attenuate Metabolic Dysregulation in Spinal Cord Injury
The purpose of this research is to test the health benefits of using functional electrical stimulation for lower extremity exercise at home.
- Trial name
- TEAM-SCI (NCT05597176)
- Testing
- Spinal Cord Injury Exercise Group
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Miami
Spinal Cord Injuries
Kinesiophobia, Fear of Falling, Functional Independence, and Psychological Status in Spinal Cord Injury
Individuals aged 18-65 years who have been clinically diagnosed with spinal cord injury and have developed paraplegia will be included in the study.
- Trial name
- NCT07549217
- Volunteers
- 70 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Vitamin D Deficiency, Spinal Cord Injury
Vitamin D Supplementation in Wheelchair Indoor Athletes
There is a high prevalence of vitamin D deficiency in Switzerland. In indoor-athletes as well as wheelchair users, vitamin D deficiency occurs even more often.
- Conditions
- Vitamin D Deficiency, Spinal Cord Injury, Drug Effects, Dietary Supplements
- Trial name
- VitD_SCI (NCT02621320)
- Testing
- Vitamin D
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Swiss Paraplegic Research, Nottwil
Paralysis, Spinal Cord Injury
Restoring Arm and Hand Function With Non-invasive Spinal Stimulation
This study is to determine if non-invasive electrical stimulation of the spinal cord can help improve hand and arm function in people with paralysis who suffered a cervical spinal cord injury.
- Trial name
- NCT01906424
- Testing
- Transcutaneous Electrical Spinal Cord Stimulation
- Where
- 2 sites in United States
- Volunteers
- 7 people
- Sponsor
- NeuroEnabling Technologies, Inc.
Spinal Cord Injury
Neuromodulation to Improve Grasping Function After SCI
The goal of this study is to restore the activities of late descending signals with a noninvasive stimulation approach in combination with hand motor training to improve hand function in persons with cervical SCI.
- Trial name
- NCT07433959
- Testing
- iTBS, PCMS, Exercise
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Spinal Cord Injury
Combining tsDCS and Exoskeleton Gait Training on Spinal Excitability in SCI
The purpose of the study is to determine whether transcutaneous spinal direct current stimulation (tsDCS) is safe for individuals with spinal cord injury (SCI). tsDCS is an electrical current applied to the skin.
- Trial name
- NCT02862080
- Testing
- cathode tsDCS, Ekso, anode tsDCS
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- The University of Texas Health Science Center, Houston
Injuries, Spinal Cord
Diaphragm Pacing After Spinal Cord Injury
Respiratory dysfunction is the leading cause of death in individuals with spinal cord injuries (SCIs). Nearly one quarter of all SCI cases involve injury to the upper spinal cord segments which impairs neural activation of the…
- Trial name
- NCT02556125
- Testing
- Diaphragm pacing
- Where
- 2 sites in United States
- Volunteers
- 16 people
- Sponsor
- University of Florida
Neurogenic Bowel Dysfunction
Stimulation for Bowel Emptying
The investigators are testing the effect of electrical stimulation of the rectum on colonic motility. Most individuals with spinal cord injury develop neurogenic bowel dysfunction, which includes slowed colonic motility, which…
- Trial name
- NCT06078176
- Testing
- Electrical Rectal Stimulation
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- VA Office of Research and Development
Surgical Site Infection
Suprafascial Vancomycin Powder for Prevention of Surgical Site Infections After Instrumented Posterior Spinal Fusion
Surgical site infections (SSI) after spine surgery may occur in up to 12% of cases and can lead to increased morbidity, and healthcare costs In this randomized controlled trial the investigators aim to prospectively investigate…
- Trial name
- VANCO (NCT04017468)
- Testing
- Vancomycin
- Where
- 7 sites in Switzerland
- Volunteers
- 450 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Spinal Cord Injuries, Cerebral Palsy
Mobile Health Self-Management and Support System for Chronic and Complex Health Conditions
This study will assess the benefits of using mobile health system designed for individuals with chronic and complex health conditions (such as those with Spinal Cord Injury,Cerebral Palsy, Spina Bifida, and Traumatic Brain…
- Conditions
- Spinal Cord Injuries, Cerebral Palsy, Spinal Dysraphism, Brain Injuries
- Trial name
- NCT02592291
- Testing
- MHealth
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Traumatic Vertebral Fractures, Compression Fractures of the Spine
Comparison of Three Treatment Strategies for Traumatic AO Type A1 Vertebral Fractures
This retrospective study evaluates three different treatment approaches used for traumatic AO Spine Type A1 (A1) vertebral fractures: orthopedic bracing, percutaneous vertebroplasty, and spinal arthrodesis.
- Conditions
- Traumatic Vertebral Fractures, Compression Fractures of the Spine, AO Type A1 Vertebral Fracture, Spinal Trauma
- Trial name
- TRAUMA-A1 (NCT07471568)
- Where
- Spain
- Volunteers
- 146 people
- Sponsor
- University of Valencia
Pressure Injury
Effectiveness of the Freedom Bed as Compared to Alternating Pressure Mattress in Treatment of Pressure Injuries in Persons With Limited Mobility Due to Traumatic Brain Injury and /or Spinal Cord Injury
This non-randomized clinical study will compare pressure injuries and the change in pressure injuries for subjects who are placed on the Freedom Bed compared to those placed on a standard Group II Low Air Loss/Alternating…
- Trial name
- NCT03118960
- Testing
- Freedom Bed, Group II Low Air Loss/Alternating Pressure Mattress
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Northeast Center for Rehabilitation and Brain Injury
Aortic Stenosis
The Effects of High Spinal Anesthesia on Heart Function, Stress Response and Pain Control in Aortic Valve Surgery
This study is looking at the effects of high spinal anesthesia (also known as total spinal anesthesia) combined with general anesthesia versus general anesthesia alone on the following: Stress response: Patients undergoing aortic…
- Trial name
- NCT00348920
- Testing
- High Spinal and General Anesthesia
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- University of Manitoba