Clinical trials: Spinal Fusion
Spondylolisthesis, Erosive Osteochondrosis in L2-S1
Comparison of Standard Fusion With "Topping Off"-System in Lumbar Spine
Does a new "topping-off" device lead to a better clinical outcome compared to standard fusion? Does this device prevent the development of adjacent instability? Does radiological adjacent instability correlate with clinical…
- Trial name
- Topping-off (NCT01224379)
- Testing
- Topping off system, monosegmental PLIF
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University of Cologne
Postoperative Ileus
Subcutaneous Methylnaltrexone Versus Placebo for Postoperative Ileus Prevention
This randomized controlled trial will prospectively evaluate the clinical benefit for subcutaneous methylnaltrexone (MNTX) in counteracting the obstipatory (causing constipation) effects of spinal surgery without increasing…
- Trial name
- NCT03852524
- Testing
- Methylnaltrexone
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Ohio State University
Degenerative Disc Disease, Back Pain, Low
The SPINUS I Study: Spinal Fusion for a Single Level SPECT/CT Positive Lumbar Degenerative Disc Disease
The aim of the present study is to find out whether fusion of a sinlge level SPECT/CT positive degenerative disc disease leads to a significant improvement of pain and disability.
- Trial name
- NCT04876586
- Testing
- Lumbar fusion
- Where
- 2 sites in Czechia
- Volunteers
- 38 people
- Sponsor
- Military University Hospital, Prague
Postoperative Pain Management
Phase 4, Controlled Study in Adult Subjects Undergoing Primary, 1-2 Level, Open Lumbar Spinal Fusion Surgery
Primary Objective: The primary objective of this study is to compare postsurgical pain control following local infiltration analgesia (LIA) with EXPAREL admixed with bupivacaine HCl versus LIA with bupivacaine HCl in adult…
- Trial name
- NCT03015961
- Testing
- EXPAREL and bupivacaine HCl, Bupivacaine HCl
- Where
- 15 sites in United States
- Volunteers
- 38 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Fusion of Spine, Lumbar Region, Anesthesia, Local
Effects of Erector Spinae Plane Block on Postoperative Pain Following Lumbar Fusion Surgery
The purpose of this study is to determine if the method for injecting local anesthesia affects patients' pain and opioid usage after surgery.
- Conditions
- Fusion of Spine, Lumbar Region, Anesthesia, Local, Pain, Postoperative, Opioid Use
- Trial name
- NCT06528288
- Testing
- Erector Spinae Plane Block, Subcutaneous Anesthesia
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Massachusetts, Worcester
Enhanced Recovery After Surgery, Spinal Fusion
Enhanced Recovery After Surgery in Oblique Lumbar Interbody Fusion
This study is a randomized controlled non-inferiority trial designed to evaluate the impact of implementing the 'Early Recovery After Surgery Clinical Pathway (ERAS CP)' on patient-reported pain levels at the time of discharge…
- Conditions
- Enhanced Recovery After Surgery, Spinal Fusion, Lumbar Spinal Stenosis, Lumbar Spondylolisthesis
- Trial name
- NCT05959343
- Testing
- Enhanced Recovery After Surgery program for Oblique Lumbar Interbody Fusion
- Where
- South Korea
- Volunteers
- 38 people
- Sponsor
- Seoul National University Hospital
Lumbar Stenosis, Spondylolisthesis
Comparison Of A Novel Hand-held Retractor-Assisted Transforaminal Lumbar Interbody Fusion By The Wiltse Approach And Posterior TLIF
In recent years, hand-held retractors have been applied to assist in Wiltse approach to perform canal decompression, causing less paraspinal muscle injury and yielding better postoperative clinical outcomes than P-TLIF.
- Trial name
- NCT06052579
- Testing
- new hand-held retractor systems-assisted WiltseTLIF surgery
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Spinal Fusion
SSEP Fluctuations Due to Dexmedetomidine During Posterior Spine Fusion
Intravenous anesthetic agents as far as inhaled agents produce a dose depended increase in latency and decrease in amplitude of SomatoSensory Evoked Potential (SSEP).
- Trial name
- NCT03236727
- Testing
- Dexmedetomidine
- Volunteers
- 25 people
- Sponsor
- George Papanicolaou Hospital
Posterior Spinal Fusion
Changes in Cerebral Oxygenation Based on Intraoperative Ventilation Strategy
The proposed research aims to investigate how different ventilation strategies may affect cerebral tissue oxygenation in the pediatric population.
- Trial name
- NCT02651103
- Testing
- NIRS
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Joseph D. Tobias