Clinical trials: Spinal Anesthesia Hypotension
Anesthesia, Spinal
Prediction of Hypotension Using Perfusion Index Following Spinal Anesthesia
It is aimed to investigate whether the perfusion index (PI) can predict hypotension after spinal anesthesia in elderly patients as much as in non-elderly patients.
- Trial name
- NCT06427382
- Testing
- Perfusion index
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Complications; Cesarean Section, Anesthesia; Adverse Effect, Spinal and Epidural
Fluid Coloading and the Incidence of Hypotension
This study was conducted to evaluate the effects of rapid crystalloid (Lactated Ringer's solution) or colloid (hydroxyethyl starch; HES) cohydration with a second intravenous access line on the incidence of hypotension and…
- Conditions
- Complications; Cesarean Section, Anesthesia; Adverse Effect, Spinal and Epidural, Other Fluid Overload
- Trial name
- NCT01741610
- Testing
- Cristalloid and colloid coloading
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Spinal Anaesthesia Induced Hypotension
Role of Ondansetron in Spinal Anaesthesia Induced Hypotension
The objective of this study is to determine the effect of ondansetron on the total consumption of norepinephrine infusion needed to prevent spinal anaesthesia induced hypotension in cesarean section.
- Trial name
- NCT06727201
- Testing
- Ondansetron (Zofran)
- Where
- Egypt
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Assiut University
Post-Dural Puncture Headache, Hypotension
Different Approaches of Spinal Anesthesia in Patients Undergoing Cesarean Section
The goal of this clinical trial is to compare different approaches of spinal anesthesia in pregnant females who are having cesarean section.
- Conditions
- Post-Dural Puncture Headache, Hypotension, Spinal Shock, Hematoma
- Trial name
- NCT05637645
- Testing
- Midline Approach, Paramedian Approach, Taylors approach
- Where
- 4 sites in Pakistan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Bahawal Victoria Hospital Bahawalpur
Anesthesia, Spinal
Norepinephrine vs. Phenylephrine for Hypotension in Low-Dose Spinal Anesthesia for Cesarean Delivery
This clinical trial was conducted to compare the effectiveness and safety of two medications, norepinephrine and phenylephrine, in preventing hypotension during low-dose spinal anesthesia for cesarean delivery (CD).
- Conditions
- Anesthesia, Spinal, Cesarean Section, Hypotension, Controlled
- Trial name
- NORPHE-CD (NCT07327320)
- Testing
- Norepinephrine, Phenylephrine
- Where
- Vietnam
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tam Anh Research Institute
Hypotension
Ondansetron in the Prevention of Hypotension in Patients Undergoing Spinal Anesthesia
Ondansetron, a potent 5-HT 3 receptor antagonist commonly used as an antiemetic. The main objective of the present study is to verify the hypothesis that blocking type 3 serotonin receptors with intravenous ondansetron reduces…
- Trial name
- NCT03973411
- Testing
- Prophylactic ondansetron
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hospital de Base
Hypotension, Nausea
Hemodynamic Protection of Preoperative Ondansetron 15 Minutes Before Spinal Anaesthesia in Caesarean Section
Spinal anaesthesia for caesarean section is the most commonly used anaesthetic choice in caesarean deliveries. This is usually associated with maternal hypotension and other adverse side effects.
- Conditions
- Hypotension, Nausea, Vomiting
- Trial name
- NCT04140058
- Testing
- Ondansetron, Normal saline
- Where
- Jordan
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Cesarean Section, Cardiac Output
Best Regimen for Phenylephrine Administration During Cesarean Section
During Cesarean delivery, phenylephrine is used to maintain the patient's blood pressure. Low blood pressure is the most common side effect of the spinal medication used to anesthetize the patient prior to the start of surgery.
- Conditions
- Cesarean Section, Cardiac Output, Hypotension
- Trial name
- NCT00996190
- Testing
- Phenylephrine
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Maternal Hypotension Syndrome, Cesarean
Norepinephrine Versus Ephedrin for Prevention of Post Spinal Anesthesia in Cesarean Section
Spinal anesthesia is still the gold standard anesthetic method for elective and urgent cesarean section, the post spinal hypotension remains the most frequent complication of this procedure and is still responsible of…
- Trial name
- NCT03719625
- Testing
- Ephedrine, Norepinephrine
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mongi Slim Hospital
Hypotension, Spinal Anesthesia
Pupillary Light Reflex to Predict Post-Spinal Hypotension in Elective Cesarean Delivery
This prospective observational cohort study investigates whether pre-anesthetic pupillary light reflex (PLR) parameters can predict the risk of hypotension following spinal anesthesia in women undergoing elective cesarean…
- Conditions
- Hypotension, Spinal Anesthesia, Cesarean Delivery
- Trial name
- NCT07678723
- Testing
- Not applicable- observational study
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Hypotension, Cesarean Delivery
Can Augmentation Index (AIx) be Used to Predict Hypotension After Spinal Anesthesia?
A fall in blood pressure (hypotension) occurs in one third of spinal anesthetics administered to pregnant patients undergoing cesarean delivery.
- Trial name
- NCT00884026
- Testing
- AIx measurement with a Sphygmacor TM
- Where
- Canada
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Pregnancy, Cesarean Delivery
Transthoracic Echocardiographic Monitoring of Cardiac Output Effects of Colloid Preload and Crystalloid Coload During Cesarean Delivery Under Spinal Anesthesia
Transthoracic echocardiography (TTE) has been introduced in anesthesia and intensive care practice to assess the volume status and predict fluid responsiveness, with a few studies performed on pregnant women (5).
- Conditions
- Pregnancy, Cesarean Delivery, Spinal Anesthesia Induced Hypotension, Cardiac Output Measurement
- Trial name
- NCT06654687
- Testing
- Transthoracic Echocardiography, Ringer lactate 1000 ml, Albumin
- Where
- Egypt
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Sameh Fathy
Post-spinal Anesthesia Hypotension
Ultrasonographic Evaluation of Internal Jugular Vein Cross Sectional Area for Prediction of Post Spinal Hypotension
The aim of this study is to evaluate the efficacy of internal jugular cross sectional area for predicting the occurrence of PSAH.
- Trial name
- NCT04780139
- Testing
- Ultrasonographic Evaluation of Internal Jugular Vein Cross Sectional Area
- Where
- Egypt
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Hypotension After Spinal Anesthesia, Hypotension During Cesarean Delivery
Ephedrine Doses to Prevent Maternal Hypotension After Spinal Anesthesia in Cesarean Section
This randomized controlled trial aims to compare the effectiveness of different doses of ephedrine infusion in preventing maternal hypotension following spinal anesthesia in parturients undergoing cesarean sections.
- Trial name
- NCT06668337
- Testing
- Ephedrine
- Where
- Nepal
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- B.P. Koirala Institute of Health Sciences
Effects of; Anesthesia, in Labor and Delivery
Phenylephrine vs. Norepinephrine Infusion After Spinal Anesthesia for Cesarean Delivery
The purpose of the study is to determine if a medication called phenylephrine, which helps to control blood pressure, is more effective as a continuous intravenous (IV) infusion compared to continuous IV norepinephrine in…
- Trial name
- NCT02354833
- Testing
- Phenylephrine, Norepinephrine
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- West Virginia University
Vomiting, Nausea
Exteriorized Versus In Situ Uterine Repair at Cesarean Delivery
This study was undertaken to compare the two techniques (exteriorized vs in situ) of uterine repair with respect to patient comfort, hemodynamic changes, surgical time and blood loss, in patients undergoing elective CD under a…
- Conditions
- Vomiting, Nausea, Pain, Hypotension
- Trial name
- NCT00452972
- Testing
- Spinal Anesthesia
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Preeclampsia, Hypotension
Phenylephrine in Spinal Anesthesia in Preeclamptic Patients
Hypotension remains a common clinical problem after induction of spinal anesthesia for cesarean delivery. Maternal hypotension has been associated with considerable morbidity (maternal nausea and vomiting and fetal/neonatal…
- Trial name
- NCT00458003
- Testing
- Ephedrine, Phenylephrine
- Where
- 2 sites in United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Hypotension
Manging Post Spinal Hypotension During Elective Cesarean Section
Spinal anesthesia is the gold standard technique for elective cesarean section. It helps to avoid risks regarding airway management and provides effective neuraxial postoperative analgesia, enabling quicker maternal recovery.
- Trial name
- EpiEph (NCT03704909)
- Testing
- Adrenaline, Ephedrine
- Where
- Tunisia
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Ben marzouk Sofiene
Hypotension
The Effect of Intravenous Prehydration on the Hemodynamic Status of Healthy Parturients Undergoing Spinal Anesthesia for Cesarean Delivery
Regional anesthesia (spinal, epidural) is considered the method of choice for anesthesia obstetric deliveries because of the ability to use fewer drugs, a more direct experience of childbirth and the capability to provide…
- Trial name
- NCT01835873
- Testing
- Lactated Ringer's, HES 130/0.42
- Where
- Greece
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Paraskevi Matsota
Myocardial Injury After Non-cardiac Surgery, Hypotension During Surgery
The Effects of General Versus Spinal Anesthesia on Postoperative Myocardial Injury
In this prospective, randomized, single-blind study, we aim to compare the effects of general anesthesia and spinal anesthesia on postoperative myocardial injury in elderly patients undergoing hip surgery.
- Conditions
- Myocardial Injury After Non-cardiac Surgery, Hypotension During Surgery, Anesthesia, General, Anesthesia, Spinal
- Trial name
- NCT06343259
- Testing
- General Anesthesia, Spinal Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital