Clinical trials: Spatial Navigation
Blindness, Visual Impairment
The Impact of the Years of Blindness on Sleep and Dreaming Processes and the Relationships With Spatial Abilities
This study aims to assess the impact of blindness on sleep and dreaming processes and the relationship with spatial perceptual performance, examining the link with clinical and psychological indices, neurobiological features, and…
- Trial name
- NCT06631807
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istituto Italiano di Tecnologia
Vestibular Dysfunction, Bilateral Vestibular Loss
Spatial Orientation, Navigation, and Neuropsychologic Function in Patients With Vestibular Implant
The vestibular system, located in the inner ear, provides information to the brain information about how head acceleration and orientation relative to gravity.
- Conditions
- Vestibular Dysfunction, Bilateral Vestibular Loss, Vestibular Implant
- Trial name
- NCT07627087
- Testing
- vestibular implant stimulation
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Massachusetts Eye and Ear Infirmary
Aging
The Entorhinal Cortex and Aerobic Exercise in Aging
The overall goal of this study is to examine how regular exercise affects brain function, spatial memory, and virtual navigation. Participation in this research study will take approximately 4 months.
- Trial name
- ECE (NCT02775760)
- Testing
- Cardiovascular endurance, Strength, balance, and flexibility
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Boston University
Memory, Delayed
Neural Correlates of Real World Spatial Navigation in Humans
The purpose of this study is to understand the neural mechanisms that support real world spatial navigation in humans using deep brain recordings and stimulation during virtual reality (VR), augmented reality, and real world…
- Trial name
- NCT04874220
- Testing
- Deep Brain Stimulation, Memory and spatial navigation tasks, Physiological Signals
- Where
- 2 sites in United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Duke University
Mild Cognitive Impairment, Alzheimer Disease
Spatial Navigation for the Early Detection of Alzheimer's Disease.
Alzheimer's Disease (AD) is the most common form of dementia and may contribute to 60-70 % of all cases. An early, accurate diagnosis of AD will become increasingly important with disease-modifying therapies.
- Conditions
- Mild Cognitive Impairment, Alzheimer Disease, Healthy Aging
- Trial name
- ALLO-task (NCT06385951)
- Testing
- Procedure for patients, Procedure for healthy controls
- Where
- Belgium
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Mild Cognitive Impairment (MCI)
Designing a Spatial Navigation Intervention Protocol Informed by Region-specific Brain Activation for Mild Cognitive Impairment
The goal of this one-arm clinical trial is to determine whether participants with mild cognitive impairment (MCI) can successfully navigate a virtual reality (VR) maze.
- Trial name
- SNav (NCT07225400)
- Testing
- Spatial Navigation training
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Cerebral Palsy, Healthy Volunteers
Assessment of Navigation Abilities in Children With Cerebral Palsy and Their Peers
Spatial navigation skills are very important in everyday activities and quality of life but spatial navigation abilities are not part of the standard process of assessment and rehabilitation of patients.
- Trial name
- NCT06320106
- Testing
- Virtual Reality baseline assessment
- Where
- Italy
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Covid19, Spatial Visualization
Mapping COVID-19 Spread in a Tertiary Hospital
One of the major problems in suppressing the spreading of an epidemic resides in understanding and monitoring its propagation patterns, and in evaluating how these are modified by enforced policies.
- Conditions
- Covid19, Spatial Visualization, Neural Network, Respiratory Disease
- Trial name
- MEDyMAP (NCT04581096)
- Testing
- no intervention
- Where
- 2 sites in Spain
- Volunteers
- 2,646 people
- Sponsor
- Hospital General Universitario de Valencia
Blindness, Blindness, Acquired
Advanced Spatiomotor Rehabilitation for Navigation in Blindness & Visual Impairment
One of the most challenging tasks for blind and visually impaired individuals is navigation through a complex environment. The goal of the present multidisciplinary study is to increase spatial-cognition abilities in people who…
- Conditions
- Blindness, Blindness, Acquired, Low Vision, Blindness, Complete
- Trial name
- NCT05377853
- Testing
- Cognitive-Kinesthetic Navigational Training
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Smith-Kettlewell Eye Research Institute
Lung Nodules, Biopsy
Efficacy and Safety of Robotic-assisted Bronchoscopy Combined With the ICNVA Strategy in Biopsy of Peripheral Pulmonary Nodules
To assess the efficacy and safety of robotic-assisted bronchoscopy system (bronchial navigation and positioning device) combined with ICNVA strategy for peripheral pulmonary nodule biopsy through a prospective, single-center…
- Conditions
- Lung Nodules, Biopsy, Navigation, Spatial
- Trial name
- NCT07136961
- Testing
- Robot-Assisted Bronchoscopy (RAB)
- Where
- China
- Volunteers
- 30 people
- Sponsor
- The First Affiliated Hospital of Nanchang University
Spatial Navigation
Modulating Goal-directed Navigation Using Noninvasive Brain Stimulation
Our specific aim is to examine the effects of TMS on spatial processing during goal-directed navigation. In these experiments the investigators will utilize a scalp-recorded brain oscillation called right posterior theta that is…
- Trial name
- NCT05801861
- Testing
- Active 10-Hz TMS to the parietal cortex, Active single pulse TMS to the parietal cortex
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Spatial Navigation, Navigation, Spatial
Investigating the Effect of Training With a Virtual Reality Driving Simulator
The proposed study aims to investigate the use of a driving simulator in a virtual reality (VR) environment to improve the cognition state and spatial navigation of individuals with mild/moderate memory impairment.
- Conditions
- Spatial Navigation, Navigation, Spatial, Dementia
- Trial name
- NCT04074655
- Testing
- Driving Simulator in a Virtual Reality Environment
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Epilepsy, Autobiographical Memory
Capturing Autobiographical Memory Formation in Real World Spaces Using Multimodal Recordings
The goal of this observational study is to develop novel methods for integrating multimodal data streams with invasive neural recordings to study autobiographical memory (AM) formation in individuals with implanted…
- Trial name
- CAPTURE (NCT06883981)
- Testing
- Free and Cued Recall Memory. Temporal Sequence and Spatial Memory
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Utah
Spatial Navigation
Exploring to Remediate Behavioral Disturbances of Spatial Cognition
Spatial navigation (SN) has been reported to be one of the first cognitive domains to be affected in Alzheimer's disease (AD), which occurs as a result of progressive neuropathology involving specific brain areas.
- Trial name
- BDSC-MCI (NCT05944601)
- Testing
- Virtual and computer-based cognitive remediation training
- Where
- Italy
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Istituto Auxologico Italiano
Alzheimer Disease, Late Onset, Mild Cognitive Impairment
Establish Diagnostic and Prognostic Models for Preclinical AD Patients Based on Multimodal MRI, Behavioral, Genetic, and Plasma Biomarkers
To establish the diagnostic and prognostic models that could help the preclinical identification of subjects at higher risk of clinical progression to mild cognitive impairment and dementia based on combined features of baseline…
- Conditions
- Alzheimer Disease, Late Onset, Mild Cognitive Impairment, Subjective Cognitive Decline
- Trial name
- NCT06561906
- Testing
- Multimodal magnetic resonance imaging scanning, behavioral, genetic and plasma biomarker testing
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Scoliosis Idiopathic, Navigation, Spatial
Preoperative and Peroperative Comparison Between 3D Spine Reconstructions
The objective is to collect data from a per-operative navigation system called SURGIVISIO during scoliosis surgeries. A research program is in progress in order super-impose pre-operative 3D reconstructions of the spine performed…
- Conditions
- Scoliosis Idiopathic, Navigation, Spatial, Fusion of Spine, Safety Issues
- Trial name
- Spine-PDCA-OR (NCT04611490)
- Testing
- Spine Fusion
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Grenoble