Clinical trials: Spasticity
Dysphagia
Effect of Masticatory Electrical Stimulation on Dysphagia in Spastic Cerebral Palsy
This study was conducted to evaluate the effectiveness of masticatory muscles electrical stimulation on oromotor skills, feeding level progress and child growth in children with dyaphagia.
- Trial name
- CP (NCT04086355)
- Testing
- oromotor exercises and neuromuscular electrical stimulations
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Spasticity as Sequela of Stroke, Stroke
Transcutaneous Spinal and Peripheral Stimulation and Wrist Robotic Therapy for Patients With Spastic Stroke
The purpose of this study is to investigate if two courses of five consecutive sessions of noninvasive spinal stimulation paired with peripheral nerve stimulation at the forearm provided by an investigational device (Doublestim™/…
- Conditions
- Spasticity as Sequela of Stroke, Stroke, Stroke Sequelae, Hemiplegia, Spastic
- Trial name
- NCT04113525
- Testing
- MyoRegulator™ System
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Northwell Health
Spasticity, Post-Stroke
A Multicenter, Open-label, Single Dose Study of the Safety and Efficacy of GSK1358820 (Botulinum Toxin Type A) in Chinese Subjects With Post-stroke Focal Upper Limb Spasticity
This trial is a multicenter, open-label study to evaluate the safety and efficacy of GSK1358820 for treatment in post-stroke subjects with focal wrist, finger and in some cases, thumb spasticity.
- Trial name
- NCT01205451
- Testing
- Botulinum toxin type A
- Where
- 13 sites in China
- Volunteers
- 109 people
- Sponsor
- GlaxoSmithKline
Cerebral Palsy, Spasticity
Exopulse Mollii Suit, Motor Functions & CP Children With Cerebral Palsy
Cerebral Palsy (CP) is is estimated to be around 1.5-3 per live birth, with prenatal factors accounting for 75% of cases. CP appears in early childhood and persists with age and is characterized by permanent lesions or…
- Conditions
- Cerebral Palsy, Spasticity, Muscle, Pain Syndrome
- Trial name
- EXOCEP2GER (NCT05885139)
- Testing
- Exopulse Mollii Suit
- Where
- 2 sites in Germany
- Volunteers
- 34 people
- Sponsor
- Exoneural Network AB
Chronic Pain, PERIPHERAL NEUROPATHY
Prospective Case Series Evaluating 6-Month and 12-Month Outcomes After Cryoneurolysis for Chronic Pain
To prospectively describe patient-centered and health utilization outcomes through 12 months after cryoneurolysis performed as routine clinical care for chronic pain at Yale.
- Conditions
- Chronic Pain, PERIPHERAL NEUROPATHY, Occipital Neuralgia, Chronic Hip Pain
- Trial name
- NCT07639060
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Yale University
Cerebral Palsy Spastic Diplegia
Effects of Dynamic Surface Exercise Training on Trunk Control and Gross Motor Functions in Children With Diplegic Cerebral Palsy
The purpose of this study was to determine the effect of dynamic surface exercise treatment on trunk control and gross motor abilities in children with spastic diplegic cerebral palsy.
- Trial name
- NCT05946096
- Testing
- Dynamic surface exercise training, conventional physical therapy
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Ayesha Hameed
Spasticity, Dry Needling
Additional Effects of Dry Needling With PNF on Spasticity and Functional Performance in Stroke
Stroke is a prevalent cause of long-term disability, with a rising global incidence. Stroke patients commonly experience impaired balance and trunk control, which limits their daily activities and quality of life.
- Conditions
- Spasticity, Dry Needling, Functional Performance
- Trial name
- NCT07013942
- Testing
- Dry Needling Group
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Foundation University Islamabad
Cerebrovascular Disorders, Spasticity, Muscle
The Effect of Ultrasound-Guided Botulinum Toxin Injections on Pain, Functionality, Spasticity, and Range of Motion in Patients With Post-Stroke Upper Extremity Spasticity
The patients between the ages of 35-80 who developed spasticity in the upper extremity after stroke will be included.. Botulinum toxin(BT-A) injection will be applied to the study group(n=16) and placebo injection to the control…
- Conditions
- Cerebrovascular Disorders, Spasticity, Muscle, Botulinum Toxin
- Trial name
- NCT05887479
- Testing
- Botulinum toxin type A, %0,9 NaCl
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Stroke
Evaluation of the Effect of Repetitive Peripheral Magnetic Stimulation on Upper Extremity Spasticity After Stroke
Spasticity is a frequent problem in post-stroke patients. It can negatively affect the functional recovery of patients and impair their quality of life.
- Trial name
- NCT05141695
- Testing
- therapeutic repetitive peripheral magnetic stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Ankara University
Pediatrics, Muscle Spasticity
BOTOX® Treatment in Pediatric Upper Limb Spasticity
This study will evaluate the safety and efficacy of BOTOX® (botulinum toxin Type A) in pediatric patients with upper limb spasticity.
- Conditions
- Pediatrics, Muscle Spasticity, Cerebral Palsy, Stroke
- Trial name
- NCT01603602
- Testing
- botulinum toxin Type A
- Where
- 45 sites in United States, Canada and 7 more
- Volunteers
- 235 people
- Sponsor
- Allergan
Sclerosis, Multiple, MS (Multiple Sclerosis)
EXOPULSE Mollii Suit, Motor Function & Multiple Sclerosis (EXOSEP 2)
The goal of this clinical trial is to demonstrate the improvement of motor functions related symptoms in patients with MS and spasticity using Exopulse Mollii suit stimulation in Multiple Sclerosis patients with spasticity.
- Conditions
- Sclerosis, Multiple, MS (Multiple Sclerosis), Spasticity, Muscle, Spastic
- Trial name
- NCT05857280
- Testing
- EXOPULSE Mollii Suit Stimulation
- Where
- United Arab Emirates
- Volunteers
- 36 people
- Sponsor
- Sheikh Shakhbout Medical City
Cerebral Palsy Spastic Hemiplegic
Effectiveness of Universal Exercise Unit Exercise on Upper Limb Strength Using Biodex Isokinetic
The aim of the study is to determine the role of designed program in the universal exercise unit on upper limb function and strength in children with spastic hemiplegia.
- Trial name
- UEU/CP (NCT07233031)
- Testing
- Experimental, Control (Standard treatment)
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Spastic Cerebral Palsy
The Effect of AFOs on the EMG of Children With CP
Children with cerebral palsy (CP) have altered gait patterns as a result of primary and secondary symptoms. Ankle-foot orthoses (AFOs) are frequently used to improve their gait.
- Trial name
- NCT06532981
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Spasticity, Lokomat
Reliability of Spasticity Measurement With Lokomat
The purpose of the study is to evaluate the reliability of spasticity measurement with Lokomat
- Trial name
- NCT02718053
- Testing
- L-stiff, Ashworth
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ospedale Generale Di Zona Moriggia-Pelascini
Cerebral Palsy, Spastic
Whole Body Vibration in Children With Cerebral Palsy
Some positive effects of whole body vibration applications in reducing spasticity, improving walking ability, and increasing walking speed have been reported in children with CP, but the evidence is not strong enough.
- Trial name
- CP (NCT05636241)
- Testing
- conventional physiotherapy program, whole body vibration training program
- Where
- Turkey (Türkiye)
- Volunteers
- 13 people
- Sponsor
- Kutahya Health Sciences University
Erector Spinae Plane Block, Opioid
Bilateral Erector Spinae Plane Block as an Opioid Sparing Technique for Selective Dorsal Rhizotomy in Pediatric Patients With Spastic Cerebral Palsy
This study aims to evaluate the efficacy of bilateral erector spinae plane block as an opioid-sparing technique for selective dorsal rhizotomy in pediatric patients with spastic cerebral palsy.
- Conditions
- Erector Spinae Plane Block, Opioid, Sparing, Selective Dorsal Rhizotomy
- Trial name
- NCT06600061
- Testing
- Erector Spinae Plane Block
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University
Cerebral Palsy, Spastic Diplegia
Walking Inclined Plane
The adaptations in kinematics and muscle activity, investigated by 3D gait analysis and dynamic electromyography recordings, will be studied in children with bilateral spastic cerebral palsy during level walking, and before and…
- Trial name
- NCT02988557
- Testing
- walking on a treadmill with a sloped surface, treadmill
- Where
- France
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Spastic Hemiplegic Cerebral Palsy
Effects of Sensory Integration Therapy in Children With Spastic Hemiplegic Cerebral Palsy
The Goal of this Clinical Trial is to learn if a treatmnet called Sensory Integration Therapy (SIT) can Improve walking,Balance and movemnet in children with a type of cerebral palsy called spastic hemiplegic Cerebral Palsy .This…
- Trial name
- NCT07733570
- Testing
- Sensory Integration Therapy, Conventional Physical Therapy
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Cerebral Palsy Spastic Hemiplegic, Functionnal Neurological Disorder
Virtual Reality-Augmented Constraint-Induced Movement Therapy Versus Conventional Constraint-Induced Therapy for Upper Limb Rehabilitation in Children With Unilateral Cerebral Palsy.
Cerebral palsy (CP) causes persistent motor and postural impairments that can limit children's functional independence and participation.
- Conditions
- Cerebral Palsy Spastic Hemiplegic, Functionnal Neurological Disorder, Upper Limb Functions, Virtual Reality Based Therapy
- Trial name
- NCT07853937
- Testing
- Rehabilitation intervention
- Where
- Tunisia
- Volunteers
- 30 people
- Sponsor
- Faculty of Medicine, Sousse
Spastic Cerebral Palsy, Spastic Gait
Effects of Different Time Period of Standing Frame on Spasticity and Gait in Children With Spastic Cerebral Palsy.
Cerebral palsy is a neurological disorder with abnormalities in muscle tone, movement disorders and motor incapability. It attributes to harm to the growing brain.
- Trial name
- NCT05113433
- Testing
- conventional physical therapy, standing frame.
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Shifa Tameer-e-Millat University