Clinical trials: Spasticity
Recurrent Crying Spells
Recurrent Crying Spells in Cerebral Palsy
This is a study of recurrent crying spells in Spastic Cerebral Palsy patients and their treatment.
- Trial name
- RCSCPSQ (NCT01955655)
- Testing
- Baclofen
- Where
- India
- Volunteers
- 70 people
- Sponsor
- Sathbhavana Brain Clinic
Cerebral Palsy, Spastic
Individualized Virtual Reality in the Upper Extremity Rehabilitation of Hemiparetic Cerebral Palsy
This study aimed to investigate the effect of individualized virtual reality therapy on upper extremity functions of children with hemiparetic cerebral palsy.
- Trial name
- NCT04630678
- Testing
- Virtual Reality Therapy, Conventional Physiotherapy, Activity Training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Hacettepe University
Cerebral Palsy, Spastic, Rehabilitation
A Pilot Study of Constraint Induced Movement Therapy in Preschool Cerebral Palsy After Botulism Toxin Injection
To establish a pilot randomized, crossover study on applying 2 constraint-induced movement therapy (CIMT) interventions in children with hemiplegic cerebral palsy after botulinum toxin injection during preschool education.
- Trial name
- NCT04179682
- Testing
- 40-hour constraint-induced movement therapy
- Volunteers
- 6 people
- Sponsor
- Changhua Christian Hospital
Muscle Spasticity, Stroke
Botulinum Toxin A Adult Gastrocnemius Muscle Study
The study aims to compare the effectiveness of BOTOX-A® (botulinun toxin A) placed between two different injection sites, namely at the proximal portion of the gastrocnemius(GCM) versus at the midbelly of the GCM.
- Trial name
- BTX-A (NCT01278576)
- Testing
- BOTOX-A®
- Where
- 2 sites in South Korea
- Volunteers
- 40 people
- Sponsor
- The Catholic University of Korea
Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay
A Home-based Rehabilitation in ARSACS
48 participants (24 women and 24 men) with autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) will participate in 2 phases : control phase (12-week usual care) and intervention phase (12-week home-based…
- Trial name
- PACE-ARSCS (NCT05768750)
- Testing
- Rehabilitation
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- Université de Sherbrooke
Cerebral Palsy (CP)
Constraint-induced Movement Therapy Combined With Functional Electrical Stimulation in Children With Cerebral Palsy
This randomized controlled trial aims to compare the effectiveness of Constraint-Induced Movement Therapy (CIMT) combined with Functional Electrical Stimulation (FES) versus CIMT alone in improving upper limb function, reducing…
- Trial name
- CIMT-FES-CP (NCT07587476)
- Testing
- Constraint-Induced Movement Therapy Combined with Functional Electrical Stimulation, Constraint-Induced Movement Therapy
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Montiha Azeem
Spastic Diplegic Cerebral Palsy
Strength Training Using Neuromuscular Electrical Stimulation For Children With Cerebral Palsy
The purpose of this study is to determine if using high-intensity, short-duration, intermittent neuromuscular electrical stimulation (NMES) is better than volitional exercise in increasing quadriceps femoris and triceps surae…
- Trial name
- NCT00356343
- Testing
- NMES Strength Training, Volitional Strength Training
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Stroke, Muscle Spasticity
Effects of Cryotherapy on Ankle Movements and Gait of Spastic Hemiparetic Subjects
The stroke has been described as the third cause of death and main cause of disability in the worldwide population. About 60% of the survivors are able to walk following the rehabilitation process, however deficits on lower limbs…
- Trial name
- NCT02736747
- Testing
- Cryotherapy
- Where
- Brazil
- Volunteers
- 16 people
- Sponsor
- Carolina Carmona de Alcântara
Spinal Cord Injury, Muscle Spasticity
Safety and Efficacy of Oral Fampridine-Sustained Release (SR) for the Treatment of Spasticity Resulting From Spinal Cord Injury
Normally, nerve fibers carry electrical impulses through the spinal cord, providing communication between the brain and the arms and legs.
- Trial name
- NCT01683838
- Testing
- Fampridine-SR
- Where
- 30 sites in United States, Canada
- Volunteers
- 204 people
- Sponsor
- Acorda Therapeutics
Cerebral Palsy
Motor Learning in People With Cerebral Palsy by Using Virtual Reality.
Cerebral Palsy (CP) is a group of permanent disorders that affect movement and posture due to a non-progressive lesion in the immature brain occurring in fetal brain development or in infancy.
- Trial name
- NCT03348943
- Testing
- Right hemiparesis, right upper limb., Right hemiparesis, left upper limb, Left hemiparesis, left upper limb
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Stroke
The Effect Of Transcranial Magnetic Stimulation In Patients With Stroke
This study is aimed to investigate the effect of continuous theta burst stimulation (cTBS) and low frequency repetitive transcranial magnetic stimulation (rTMS) on upper extremity spasticity and functional recovery in patients…
- Trial name
- NCT04562415
- Testing
- Active Repetitive Transcranial Magnetic Stimulation Therapy, Active Continuous Theta Burst Stimulation Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Upper Limb Spasticity
A Clinical Study to Evaluate the Safety and Efficacy of JHM03 in Adult Patients With Upper Limb Spasticity
This is a phase Ib/II clinical study to evaluate the safety and efficacy of recombinant botulinum toxin type A（JHM03）in adult patients with upper limb spasticity.
- Trial name
- NCT06584240
- Testing
- Sequence 1, Sequence 2, Sequence 3
- Where
- 20 sites in China
- Volunteers
- 84 people
- Sponsor
- JHM BioPharma (Tonghua) Co. , Ltd.
Spinal Cord Injury
Effects of Marijuana on Neuropathic Pain and Spasticity in Spinal Cord Injury Patients
The goal of this clinical trial is to compare effects of marijuana or cannabis on neuropathic pain and spasticity in spinal cord injury patients.
- Trial name
- NCT06190470
- Testing
- Cannabis
- Where
- Thailand
- Volunteers
- 20 people
- Sponsor
- Khon Kaen University
Cerebral Palsy, Spastic
Effect of the Nutritional Support System on Neuromotor Alterations in Patients With Cerebral Palsy
Study to determine the impact of a nutritional support system (NSS) on neuromotor alterations in patients with cerebral palsy.
- Conditions
- Cerebral Palsy, Spastic, Malnutrition
- Trial name
- NSS-PC (NCT05648422)
- Testing
- Probiotics, NSS Nutritional Support System, Deworming
- Where
- Mexico
- Volunteers
- 144 people
- Sponsor
- Anahuac University
Sjogren-Larsson Syndrome (SLS)
Sjogren-Larsson Syndrome: Natural History, Clinical Variation and Evaluation of Biochemical Markers
Sjogren-Larsson syndrome (SLS) is a rare genetic disease in which patients typically exhibit ichthyosis (dry, scaly skin), intellectual disability, spasticity, seizures and a distinctive maculopathy.
- Trial name
- SLS (NCT01971957)
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Nebraska
Stroke Sequelae, Spasticity, Muscle
Effects of CRet Associated With Functional Massage (F.M) on Gait and Functionality in Post-stroke Spasticity
The purpose of this study is to assess the immediate effects of CRet associated to Functional Massage (F.M) in terms of gait and functionality after stroke
- Conditions
- Stroke Sequelae, Spasticity, Muscle, Massage, Electrotherapy
- Trial name
- NCT04851756
- Testing
- CRet
- Where
- Spain
- Volunteers
- 36 people
- Sponsor
- Universitat Internacional de Catalunya
Hyperhidrosis, Muscle Spasticity
Safety and Efficacy of BOTOX® (Botulinum Toxin Type A) in Korea
This post marketing surveillance study in Korea will evaluate the safety and efficacy of BOTOX (botulinum toxin Type A) in patients who receive treatment according to standard of care for primary axillary hyperhidrosis, focal…
- Conditions
- Hyperhidrosis, Muscle Spasticity, Glabellar Lines
- Trial name
- NCT02043145
- Testing
- botulinum toxin Type A
- Where
- South Korea
- Volunteers
- 727 people
- Sponsor
- Allergan
Spasticity, Muscle
Obturator Cryoneurotomy for Hip Adductor Spasticity
The purpose of the study is to measure the effects of obturator nerve cryoneurotomy, on clinical measures in adult (ages 19+) and paediatric (ages 12-18) patients with hip adductor spasticity, who will receive this procedure as a…
- Trial name
- NCT05147441
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Vancouver Island Health Authority
Stroke, Spasticity as Sequela of Stroke
Dynamic Lycra Orthosis as an Adjunct to Botulinum Toxin-A Injection for Post-stroke Spasticity
Upper extremity splints are one of the nonpharmacologic treatments used to treat hypertonicity after stroke. The purpose of splinting is to support, to position, to immobilize, to prevent contracture and deformities, to reduce…
- Conditions
- Stroke, Spasticity as Sequela of Stroke, Upper Limb Hypertonia
- Trial name
- NCT03546959
- Testing
- Lycra sleeve, Rehabilitation, Botulinum Toxin
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Marmara University
Stroke
Neurodynamics on Spasticity in Upper Extremity of Stroke Patients.
Data will be collected from 40 patients with hemiplegia, caused by stroke from DHQ hospital Jhelum. its an RCT Neurodynamics with conventional treatment to experimental group and conventional treatment alone to control group will…
- Trial name
- NCT03822923
- Testing
- Experimental group, Control group
- Where
- Pakistan
- Volunteers
- 41 people
- Sponsor
- Riphah International University