Clinical trials: Spasticity
Spastic Dysphonia, Healthy
Study of Air Stream in Voice Production
This study will investigate and compare the air stream during voice production in patients with abductor spasmodic dysphonia and in normal volunteers.
- Trial name
- NCT00015795
- Testing
- airway interruption test
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Hemiplegia, Spastic
THE EFFECTS OF SUBTALAR JOINT MOBILIZATION ON PATIENTS WITH CHRONIC STROKE
Adequate ankle motion for normal gait ranges from 10° to 15° of dorsiflexion passive range of motion (DF-PROM) to allow the tibia to move over the talus.
- Trial name
- NCT03788629
- Testing
- Talocrural joint MWM mobilization, Subtalar joint MWM mobilization
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Stroke
Robot Aided Rehabilitation - Multi-joint Evaluations
Sensory and motor impairments following stroke can lead to substantial disability involving the arm and hand. The investigator hypothesized that excessive local and cross-coupled stiffness, diminished individuation and…
- Trial name
- Aim1 (NCT02359812)
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Amyotrophic Lateral Sclerosis, Frontotemporal Dementia
Phenotype, Genotype & Biomarkers in ALS and Related Disorders
The goals of this study are: (1) to better understand the relationship between the phenotype and genotype of amyotrophic lateral sclerosis (ALS) and related diseases, including primary lateral sclerosis (PLS), hereditary spastic…
- Conditions
- Amyotrophic Lateral Sclerosis, Frontotemporal Dementia, Primary Lateral Sclerosis, Hereditary Spastic Paraplegia
- Trial name
- NCT02327845
- Where
- 15 sites in United States, Germany and 1 more
- Volunteers
- 708 people, healthy volunteers welcome
- Sponsor
- University of Miami
Stroke
Evaluation of BOTOX® With Rehabilitation Therapy for the Treatment of Wrist and Hand Spasticity in Post-Stroke Patients
The present study is designed to determine the safety and effectiveness of injections of BOTOX® in spastic muscles of the arm and hand compared with injections of saline (which would do nothing) when combined with rehabilitation…
- Trial name
- Botox/Rehab (NCT00565201)
- Testing
- Botox and rehab
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Emory University
Cerebral Palsy, Muscle Spasticity
Effect of Botox and Vibration on Bone in Children With Cerebral Palsy
Cerebral palsy (CP) is a neuromuscular disorder that affects approximately 800,000 individuals in the U.S. An estimated 70-80% of these individuals have spasticity which affects ambulation and requires management.
- Trial name
- NCT01803464
- Testing
- Low-magnitude vibration, Botox
- Where
- 2 sites in United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Cerebral Palsy, Spastic Diplegia
Walking Inclined Plane
The adaptations in kinematics and muscle activity, investigated by 3D gait analysis and dynamic electromyography recordings, will be studied in children with bilateral spastic cerebral palsy during level walking, and before and…
- Trial name
- NCT02988557
- Testing
- walking on a treadmill with a sloped surface, treadmill
- Where
- France
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Muscle Spasticity, Paralysis; Cerebral
The Decline in Walking Performance in Adults With Cerebral Palsy - Influence of Performance Fatigability
Due to an early brain injury occurring in antenatal or postnatal, cerebral palsy (CP) causes alteration in motor function with posture and gait disorders.
- Trial name
- FAT-GAIT (NCT06163950)
- Testing
- Fatigability assessment
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Gait, Spastic, Reliability
Reliability of Newly-acquired Gait in Toddlers With a Typical Development and a Unilateral Cerebral Palsy
gait reliability study of toddlers with typically developing and with unilateral cerebral palsy during the first 6 months of independent walking
- Trial name
- ReliabBB-AQM (NCT04559776)
- Testing
- gait analysis
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- National Clinical Center for Neuropsychomotor Recovery for Children Dr. Nicolae Robanescu
Muscle Spasticity, Healthy
Physiologic Studies of Spasticity
This study will provide information about changes that occur in the motor neurons of the spinal cord (the nerve cells that control the muscles) when the motor cortex (the region of the brain that controls movement) is unable to…
- Trial name
- NCT00014976
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Spinal Cord Injuries
Reciprocal Inhibition Versus Reciprocal Facilitation In Spinal Cord Injury Patients
Reciprocal inhibition is a medulla spinalis control mechanism that facilitates motor activities in healthy people. As the agonist muscle contracts, the antagonist muscle is inhibited so that the agonist action can take place…
- Trial name
- NCT05985031
- Testing
- Tendon tap, Tibial nerve stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Spasticity
A Prospective Study of Spasticity in Individuals With Multiple Sclerosis
This study is expected to contribute to the body of knowledge on the benefits of individuals with MS taking glatiramer acetate (Copaxone®).
- Trial name
- NCT01111435
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Fraser, Cira, Ph.D., RN, ACNS-BC
Gait, Spastic
Walking Ability and Limit of Stability in Children With Spastic Cerebral Palsy
Trunk control in children with spastic Cerebral Palsy (CP) is impaired. They have weaker trunk muscle strenght, and insufficient sitting/standing balance according to their developing peers.
- Trial name
- NCT05583929
- Testing
- GAITRite gaitway system, Bertec Balance System
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Muş Alparslan University
Laryngeal Disease, Spastic Dysphonia
Characteristics of Idiopathic Familial Voice Disorders
The purpose the study is to determine the genetic causes of specific voice disorders that run in families. Researchers are particularly interested in two conditions; 1. Spasmodic dysphonia 2.
- Conditions
- Laryngeal Disease, Spastic Dysphonia, Voice Disorder
- Trial name
- NCT00001552
- Where
- 4 sites in United States, United Kingdom
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Cerebral Palsy
Protocol Validation of Dynamometric Measurement of Passive Inter-segmental Stiffness and Spasticity in Children With Cerebral Palsy
Cerebral palsy (CP) refers to a group of movement and posture disorders responsible for activity limitation due to brain damage that occurs during fetal development or during the first year of a child's life.
- Trial name
- NCT04596852
- Testing
- Assessment of the reliability of a protocol characterizing intersegmental hyper-resistance to passive stretch
- Where
- France
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Fondation Ellen Poidatz