Clinical trials: Spasticity
Stroke, Hemiparesis
Recovery of Motor Skills With the Use of Artificial Intelligence and Computer Vision
To investigate the impact of algorithms utilizing artificial intelligence technology and computer vision on the recovery of motor functions within the context of rehabilitation practice for patients who have experienced a…
- Conditions
- Stroke, Hemiparesis, Spasticity as Sequela of Stroke, Dysmetria
- Trial name
- NCT06183970
- Testing
- AssistI patients, Habilect patients
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Federal Center of Cerebrovascular Pathology and Stroke, Russian Federation Ministry of Health
Stroke, Walking, Difficulty
Agonist and Antagonist Muscle Activations in the Lower Limbs During Walking After Central Nervous System Injury
The retrospective study investigates the part of responsibility of neuromuscular disorders associated with chronic hemiparesis in walking impairment.
- Conditions
- Stroke, Walking, Difficulty, Spasticity/Paresis
- Trial name
- NEUROGAIT (NCT06107556)
- Testing
- Gait analysis
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Henri Mondor University Hospital
Basal Energy Expenditure, Spasticity
Energy Costs of Spasticity in Spinal Cord Injury: A Pilot Investigation
The purpose of this study is to determine if there is a relationship between spasticity and relative changes in Basal Energy Expenditure in persons with spinal cord injury.
- Trial name
- NCT00572845
- Testing
- Weaning of Antispasticity Medication
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Cerebral Palsy, Spastic, Posture
The Effect of Trunk Control on Respiratory Muscle Strength
Cerebral palsy (CP) can be defined as a group of disorders of movement and posture, causing activity limitation that are attributed to nonprogressive deficits that take place in the immature brain.
- Conditions
- Cerebral Palsy, Spastic, Posture, Respiratory Muscle Strength, Activities of Daily Living
- Trial name
- NCT03209310
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Gazi University
Spinal Cord Injuries, Muscle Spasticity
Effects of Zolmitriptan on Sensory Transmission After Spinal Cord Injury
After spinal cord injury, patients develop a spastic syndrome that is characterized by hyperactive reflexes, increased muscle tone, clonus and involuntary muscle spasms.
- Trial name
- NCT01587170
- Where
- Canada
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Stroke, Traumatic Brain Injury
Validation of an Obstacle Course Used in Patients With Muscle Tightness
This study is being conducted to compare healthy patients versus patients with muscle tightness in their leg(s) after an acquired brain injury using walking trials time, a balance test, and foot pressure data.
- Conditions
- Stroke, Traumatic Brain Injury, Multiple Sclerosis, Spasticity
- Trial name
- NCT00776048
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Spastic Ataxia
Phenotypes, Biomarkers and Pathophysiology in Spastic Ataxias
The aim of this study is to determine the clinical spectrum and natural progression of Spastic Ataxias (SPAX) and related disorders in a prospective multicenter natural history study, identify digital, imaging and molecular…
- Trial name
- SPAX-PBP (NCT04297891)
- Testing
- Clinical rating scale to measure Ataxia disease severity and progression, Clinical rating scale to measure spastic paraplegia disease severity and progression, Disease-specific severity index for adults with autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS)
- Where
- 9 sites in Canada, France and 5 more
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Dr. Rebecca Schule
Cerebral Palsy, Mixed, Cerebral Palsy, Spastic
Movement Characterization in Spastic/Dystonic Cerebral Palsy Using Haptic Feedback in Virtual Reality
This game-like intervention using virtual reality will provide an objective and quantitative characterization of dystonia and spasticity presentations in cerebral palsy, even if combined, through the process of motor learning.
- Trial name
- NCT03744884
- Testing
- Force efforts with haptic feedback in virtual reality.
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Cerebral Palsy, Muscle Hypertonia
Hypertonia in Patients With Cerebral Palsy
This study will classify types of hypertonia in patients with cerebral palsy and determine if the classifications are reasonable in relation to the functional task of walking. Hypertonia is an abnormal increase in muscle tension.
- Trial name
- NCT00123708
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Stroke, Cerebral
Benefits of Extracorporeal Shockwave Therapy to Reduce Spasticity in Stroke/CP
This Study will help to explain us that ExtracorporealShockwave therapy can reduce spasticity in Stroke Patient,help them to restore their abilities and ROM.Therapy reduces dependency rate of patient.Also seen this therapy shows…
- Trial name
- NCT06548321
- Testing
- Extracorporeal Shockwave Therapy
- Where
- Pakistan
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Superior University
Tropical Spastic Paraparesis
MRI Brain Studies in Patients With HTLV-1 Associated Myelopathy/Tropical Spastic Paraparesis
This study will use three different magnetic resonance imaging (MRI) techniques to study HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/STP)-a disease of slowly progressive weakness in the legs.
- Trial name
- NCT00034723
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Stroke, Chronic Stroke
Neural Operant Conditioning
The goal of this clinical trial is to learn if operant conditioning can reduce spasticity in order to improve walking in stroke patient.
- Conditions
- Stroke, Chronic Stroke, Gait, Hemiplegic, Gait, Spastic
- Trial name
- NCT06113965
- Testing
- Peripheral Nerve Stimulation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- MetroHealth Medical Center
Brain-injury
Effectiveness of Aquatic Theraphy in Spasticity: Watsu and Halliwick
Treatment with ACD patients will be carried out through the application of aquatic therapies, being the Halliwick Concept and the Watsu Method together with a time of immersion in hot water.
- Trial name
- NCT05151497
- Testing
- Experimental group:Halliwick + Método Watsu, Control group:Halliwick
- Where
- 3 sites in Spain
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Cadiz
Muscle Spasticity, Stroke
Measurements of Displacement Amplitude and Angular Velocities During Passive Extension of the Wrist and Hand Complex in Stroke Patients
The main objective of this monocentric prospective study is to evaluate the amplitudes and angular velocities of extension of the hand and wrist joints during passive mobilization by a physiotherapist in healthy subjects and…
- Trial name
- PHYSIOHAND (NCT04502927)
- Testing
- Passive extension mobilization of the hand and wrist joints
- Where
- France
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Groupe Hospitalier de la Region de Mulhouse et Sud Alsace
Cerebral Palsy, Gait Disorders, Neurologic
Precision Gait Retraining for Children With Cerebral Palsy
This project will develop the first sensor-based mobile Pelvic Assist Device (mPAD) that can deliver precise, adaptable, pelvic control to restore natural coordination of upper- and lower-limb movements during gait in children…
- Trial name
- NCT04717323
- Testing
- mPAD (or TPAD) Pelvic Assist Device, No Intervention
- Where
- 2 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Altec Inc.
Spastic Hemiplegia
Biomechanical Muscle Properties and Balance in Children With Spastic Hemiplegia
this study will be conducted to investigate the relationship between muscle tone and dynamic stiffness during balance control and postural stability in children with spastic hemiplegia
- Trial name
- BMPB-HCP (NCT07538297)
- Testing
- hemiplegic group, normal group
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- South Valley University
Cerebral Palsy
Motor Learning in People With Cerebral Palsy by Using Virtual Reality.
Cerebral Palsy (CP) is a group of permanent disorders that affect movement and posture due to a non-progressive lesion in the immature brain occurring in fetal brain development or in infancy.
- Trial name
- NCT03348943
- Testing
- Right hemiparesis, right upper limb., Right hemiparesis, left upper limb, Left hemiparesis, left upper limb
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Spastic Cerebral Palsy
3D-Microscopic Muscle Architecture in Cerebral Palsy
The focus of this study is to understand and define the mechanisms of the altered muscle development and growth on a microscopic level within a long-term perspective in children with cerebral palsy and to relate these findings to…
- Trial name
- 3D-MMAP (NCT06584851)
- Where
- Belgium
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Hemiparesis;Poststroke/CVA
Strengthening in Sub-acute Stroke Survivors: A Randomized Controlled Trial
The goal of this study is to compare between Eccentric training and conventional therapy in sub-acute stroke survivors. The primary objective of this study is to evaluate improvements in gait speed after four months of ET in…
- Trial name
- NCT06140381
- Testing
- Eccentric training, Conventional therapy
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Clinique Du Parc de Belleville
Stroke, Spasticity, Muscle
Individualized rTMS Based on fNIRS to Spasticity
Stroke is of high morbidity and mortality, and surviving patients are often unable to take care of themselves because of severe motor dysfunction.
- Conditions
- Stroke, Spasticity, Muscle, Rehabilitation
- Trial name
- NCT05318586
- Testing
- individual rTMS based on fNIRS, Traditional rTMS strategy
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University