Clinical trials: Spasticity, Post-Stroke
Post Stroke Seizure, Spastic Foot
Evaluation of Tibial Nerve Selective Neurotomy Compared to Botulinum Toxin Injections for Spastic Foot Treatment in Post-stroke Patients According to a Goal-centered Approach
In France, more than 110.000 patients are hospitalized for stroke per year. It is the leading cause of sudden disabilities in adults.
- Trial name
- FOOTNEUROTOX (NCT05874154)
- Testing
- Tibial nerve selective neurotomy, Botulinum toxin injection
- Where
- 4 sites in France
- Volunteers
- 60 people
- Sponsor
- Hospices Civils de Lyon
Post Stroke Upper Limb Spasticity
A Single Center, Phase I Clinical Trial to Evaluate the Safety of LIZTOX Inj in the Treatment of Post Stroke Upper Limb Spasticity
Investigational Product: LIZTOX inj 100unit(HU-014) Title : A Single Center, Phase I Clinical Trial to Evaluate the Safety of LIZTOX Inj in the Treatment of Post Stroke Upper Limb Spasticity Sites and investigators : Asan Medical…
- Trial name
- NCT04415346
- Testing
- HU-014 Inj
- Where
- South Korea
- Volunteers
- 13 people
- Sponsor
- Huons Co., Ltd.
Spasticity, Muscle, Stroke Sequelae
Valuation of the Evolution of Passive Mobility in the Spastic Upper Limb After Injection of Abobotulinumtoxin(Dysport®)
Assessing the objective measurement of passive joint mobility (ROM) in the spastic upper limb with Jost's pattern III in patients with post-stroke spasticity after infiltration with BoNT-A allows to objectify the increase in…
- Conditions
- Spasticity, Muscle, Stroke Sequelae, Movement Disorders
- Trial name
- ROM-ICTUS (NCT05151874)
- Testing
- Abobotulinum toxin A
- Where
- Spain
- Volunteers
- 12 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Stroke
Dry Needling for Spasticity in Stroke
Stroke is the leading cause of physical disability due to the presence of spasticity. Different needling techniques, including Botulinum Toxin A are proposed for management of spasticity; however results are conflicting.
- Trial name
- NCT02377804
- Testing
- Dry needling, Physical Therapy, stainless steel needles (0.3mm x 50mm)
- Where
- 2 sites in Spain
- Volunteers
- 20 people
- Sponsor
- Universidad Rey Juan Carlos
Stroke, Post-Stroke Spasticity
Effect of Extracorporeal Shock Wave Therapy on Spasticity and Mobility in Stroke Patients
This study aims to evaluate the effectiveness of extracorporeal shock wave therapy (ESWT) in individuals with lower limb spasticity following stroke.
- Conditions
- Stroke, Post-Stroke Spasticity, Lower Limb Spasticity
- Trial name
- ESWT-STROKE (NCT07523243)
- Testing
- Extracorporeal Shock Wave Therapy (ESWT)
- Volunteers
- 85 people
- Sponsor
- Istanbul Medipol University Hospital
Stroke, Muscle Spasticity
SIRS-ESWT Trial: Shoulder Internal Rotator Spasticity Trial Treated With Extracorporeal Shock Wave Therapy Trial
Extracorporeal shock wave therapy (ESWT) has shown potential in reducing post-stroke limb spasticity. This study aims to evaluate the efficacy of focused ESWT on shoulder internal rotator spasticity in post-stroke patients.
- Trial name
- NCT06674785
- Testing
- focused extracorporeal shock wave therapy (ESWT)
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital
Stroke
Evaluation of BOTOX® With Rehabilitation Therapy for the Treatment of Wrist and Hand Spasticity in Post-Stroke Patients
The present study is designed to determine the safety and effectiveness of injections of BOTOX® in spastic muscles of the arm and hand compared with injections of saline (which would do nothing) when combined with rehabilitation…
- Trial name
- Botox/Rehab (NCT00565201)
- Testing
- Botox and rehab
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Emory University
Stroke, Spastic Hemiplegia
BTX-A and Mirror Therapy for Chronic Stroke Spasticity
Stroke is one of the leading causes of disability worldwide, particularly affecting the upper extremities and thus negatively impacting patients' activities of daily living and quality of life.
- Trial name
- NCT07331844
- Testing
- Botulinum toxin type A (Botox®, Allergan), Mirror Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Stroke
Changes in Echogenicity and Muscle Stiffness in Elastography After Botulinum Toxin Injection a Spastic Muscle
Muscle alterations and modifications passive biomechanical properties that occur on a spastic muscle contribute to functional disorders involved in spasticity.
- Trial name
- NCT02550509
- Testing
- ultrasound echogenicity, elastography
- Where
- France
- Volunteers
- 6 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Spasticity, Muscle, Stroke
Multimodal Instrumented Assessment of Post-stroke Elbow
The proposed clinical trial will employ the NEUROExos Elbow Module (NEEM), an active robotic exoskeleton, for the passive mobilization and active training of elbow flexion and extension in 60 sub-acute and chronic stroke patients…
- Conditions
- Spasticity, Muscle, Stroke, Upper Limb
- Trial name
- NCT04484571
- Testing
- Neuroexsos elbow module
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Azienda USL Toscana Nord Ovest
Post-stroke Upper Limb Spasticity
Safety and Efficacy of CKDB-501A in Subjects With Post-stroke Upper Limb Spasticity
Multicenter, randomized, double-blind, active-controlled, parallel-design study to evaluate the safety and efficacy of CKDB-501A in Subjects with Post-stroke Upper Limb Spasticity
- Trial name
- NCT05382767
- Testing
- CKDB-501A, Botox®
- Where
- 2 sites in South Korea
- Volunteers
- 24 people
- Sponsor
- CKD Bio Corporation
Stroke, Upper Limb Spasticity
Study to Assess Impact of Dysport Injections Early After Stroke on Upper Limb Spasticity Progression
The purpose of this study is to investigate if early administration (i.e. within 12 weeks after stroke) of Dysport® 500 U injections may delay the appearance or the progression of upper limb symptomatic spasticity.
- Trial name
- ONTIME Pilot (NCT02321436)
- Testing
- Botulinum toxin type A
- Where
- 4 sites in Malaysia, Philippines and 2 more
- Volunteers
- 42 people
- Sponsor
- Ipsen
Stroke, Spasticity, Muscle
Multiphasic Neuroplasticity Based Training Protocol With Shock Wave Therapy For Post Stroke Spasticity
this study will be conducted to f find the effects of multiphasic neuroplasticity based training protocol with Shock Wave Therapy on Neurophysiological, Morphological and Functional Parameters of Post Stroke Spasticity.
- Trial name
- NCT05405140
- Testing
- Shock wave therapy with multiphasic neuroplasticity based training protocol, Conventional physical therapy
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University