Clinical trials: Somatic Symptom
Postoperative Pain After Laparoscopic Cholecystectomy
Lateral Versus Subcostal TAP Block for Drain-Site Analgesia in Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy is a commonly performed surgical procedure. Despite its minimally invasive nature, patients may experience significant postoperative pain, particularly at trocar insertion sites and surgical drain…
- Trial name
- DRAINPAIN (NCT07661576)
- Testing
- Bilateral Subcostal TAP Block, Lateral TAP Block Plus Contralateral Subcostal TAP Block
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Turgut Ozal University
Somatic Symptom Disorder (DSM-V)
Effect of Venlafaxine Versus Dosulepin in Pain Predominant Somatic Symptom Disorder
Somatic symptom disorder (SSD) is marked by persistent physical complaints, often involving pain, alongside excessive thoughts or behaviors related to health, which substantially disrupt daily functioning.
- Trial name
- NCT06803485
- Testing
- Venlafaxine, Dosulepin
- Where
- India
- Volunteers
- 84 people
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Somatization Disorder, Functional Disorders
Mindfulness-based Cognitive Therapy for Patients With Functional Disorders
The aim of the study is to examine the efficacy of Mindfulness-Based Cognitive Therapy (MBCT) in patients with functional disorders defined as severe Bodily Distress Disorder.
- Conditions
- Somatization Disorder, Functional Disorders, Bodily Distress Disorder
- Trial name
- NCT00497185
- Testing
- Mindfulness-Based Cognitive Therapy for Functional Disorders
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- University of Aarhus
Somatic Symptom Disorder
Use Repetitive Transcranial Magnetic Stimulation to Treat Somatic Symptom Disorder
This is a randomized double-blind sham-controlled crossover study; the interventions are high-frequency rTMS stimulation on left DLPFC and sham control. The study population is the patient with somatic symptom disorder.
- Trial name
- NCT05161819
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital
Somatization Disorder
Assessment of Somatic Symptom Burden
The Patient Health Questionnaire-15 (PHQ-15) is a frequently used questionnaire to assess somatic symptom burden. The Somatic Symptom Scale China (SSS-CN) was recently developed as a comprehensive self-report instrument in…
- Trial name
- NCT03321409
- Testing
- The general population, Patients with suspected CAD
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Patients, Anxiety Disorders
LSD Treatment in Persons Suffering From Anxiety Symptoms in Severe Somatic Diseases or in Psychiatric Anxiety Disorders
Background: Lysergic acid diethylamide (LSD) was extensively investigated in humans in the 1950s and 1960s. Particularly, LSD attenuated anxiety in patients with cancer.
- Trial name
- LSD-assist (NCT03153579)
- Testing
- LSD
- Where
- 2 sites in Switzerland
- Volunteers
- 46 people
- Sponsor
- University Hospital, Basel, Switzerland
Tinnitus, Acoustic Stimulation
Different Stimuli Were Given to Patients With Chronic Pure Tone Tinnitus to Verify the Effective Treatment of Tinnitus.
In this experiment, patients with chronic pure tone tinnitus were divided into three groups to receive auditory stimulation, somatosensory stimulation, vestibular stimulation and combined stimulation, in order to find an…
- Conditions
- Tinnitus, Acoustic Stimulation, Somatic Stimulation, Vestibular Stimulation
- Trial name
- NCT04118907
- Testing
- multiple sensory stimulation
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Dan Su
Somatic Symptom Disorder (DSM-V)
Cognitive-Behavioral Therapy Enriched With Emotion Regulation Training for Multiple Somatoform Symptoms
The purpose of this study is to evaluate whether cognitive-behavioral therapy enriched with strategies from emotion regulation training leads to better improvement in somatic symptoms and comorbid problems than…
- Trial name
- ENCERT (NCT01908855)
- Testing
- Cognitive-behavioral therapy + emotion regulation training for patients with multiple somatoform symptoms, Cognitive-behavioral therapy for patients with multiple somatoform symptoms
- Where
- 7 sites in Germany
- Volunteers
- 255 people
- Sponsor
- Philipps University Marburg
Hyperacusis
Exploratory Study on the Role of Somatic Modulation in Hyperacusis
This study focuses on patients with a primary complaint of hyperacusis. Hyperacusis has been defined as 'abnormally reduced tolerance to sound' and is commonly associated with tinnitus.
- Trial name
- NCT04693819
- Testing
- Somatic modulation
- Where
- Belgium
- Volunteers
- 18 people
- Sponsor
- University Hospital, Antwerp
Aphasia, Development, Human
Cognitive Functioning in Adults With Somatic Diseases and General Population From a Biopsychosocial Perspective
The goal of this observational study is to investigate cognitive functioning profiles in adults with neurologically recognized aphasic syndromes and general population.
- Conditions
- Aphasia, Development, Human, Neuropathology
- Trial name
- NCT06365658
- Testing
- Psychological assessment
- Where
- Poland
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Bartosz M. Radtke
Post COVID-19 Condition (PCC)
Basel Long COVID-19 Cohort Study and Digital Long COVID Substudy
The Basel Long COVID Cohort Study (BALCoS) is a registry-based cohort study that focuses on the patients' present health status, symptoms, the course of these symptoms, and potential mechanisms involved.
- Trial name
- BALCoS/DiLCoS (NCT05781893)
- Testing
- Digital intervention (DiLCoS), Data collection
- Where
- Switzerland
- Volunteers
- 196 people
- Sponsor
- University Hospital, Basel, Switzerland
Somatic Pain
Investigation of Low-intensity Focused Ultrasound Pressure
Investigating the relationship between input pressure of low-intensity focused ultrasound and an evoked potential in both eeg and fMRI.
- Trial name
- NCT06343883
- Testing
- low-intensity focused ultrasound - low pressure, low-intensity focused ultrasound - medium pressure, low-intensity focused ultrasound - high pressure
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Virginia Polytechnic Institute and State University
Quality of Life, Neuropathic Pain
Effects of Occlusal Splint and Therapeutic Home Exercises
In this randomized controlled study, investigators planned to investigate the efficacy of oral occlusive splint and therapeutic home exercises in increasing the quality of life and reducing somatic and neuropathic pain in…
- Conditions
- Quality of Life, Neuropathic Pain, Somatic Pain
- Trial name
- NCT04116255
- Testing
- Mandibular oral occlusal splint, Temporomandibular joint Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 101 people
- Sponsor
- Ankara Training and Research Hospital
Somatic Symptom Disorder
Developing an Integrated Psychotherapy With Cognitive-behavioral Therapy and Biofeedback Therapy for Somatic Symptom Disorder
This research program is aimed to develop a integrative psychotherapy (including CBT and biofeedback therapy) and to examine its efficacy on treatment of somatic symptom disorder.
- Trial name
- NCT05792930
- Testing
- cognitive-behavioral therapy and biofeedback therapy
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Somatic Symptom and Related Disorders, Somatic Symptom Disorder
Telehealth Group-based Emotional Awareness and Expression Therapy for Patients With Persistent Physical Symptoms: A Pilot Study
Delivering Emotional Awareness and Expression Therapy (EAET) through digital or telehealth platforms in a group format offers several key advantages.
- Conditions
- Somatic Symptom and Related Disorders, Somatic Symptom Disorder, Functional Somatic Disorder, Functional Somatic Syndrome
- Trial name
- NCT06631963
- Testing
- Emotional Awareness and Expression Therapy
- Where
- Sweden
- Sponsor
- Daniel Maroti
Clonal Hematopoiesis, Clonal Hematopoiesis of Indeterminate Potential
CHIP in Health and Disease
Clonal hematopoiesis (CH), including clonal hematopoiesis of indeterminate potential (CHIP), is an age-associated condition characterized by the expansion of hematopoietic stem and progenitor cell clones carrying acquired somatic…
- Conditions
- Clonal Hematopoiesis, Clonal Hematopoiesis of Indeterminate Potential, Clonal Cytopenia of Undetermined Significance (CCUS), Myelodysplastic Syndrome
- Trial name
- CHIP2 (NCT07780552)
- Where
- Austria
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- VASCage GmbH
Somatic Symptom Disorder
App-Based Self-Management for Somatic Symptom Disorder and MUS: A Pilot Study
Objectives The primary objective of this study is to evaluate the effectiveness of an eight-week self-management mobile application for adults experiencing somatic symptom disorder (SSD) or medically unexplained symptoms (MUS).
- Trial name
- NCT07296406
- Testing
- Arm I (App Intervention), Arm II (Waitlist Control)
- Where
- South Korea
- Volunteers
- 46 people
- Sponsor
- Gangnam Severance Hospital
Fibromyalgia, Irritable Bowel Syndrome
A Computer-Based Intervention for Medically Unexplained Physical Symptoms
In this study 60 people with medically unexplained physical symptoms (MUPS) will receive either a 6-session resilience skill building intervention provided fully online or a weekly computerized journaling assignment.
- Conditions
- Fibromyalgia, Irritable Bowel Syndrome, Chronic Fatigue Syndrome
- Trial name
- NCT00468013
- Testing
- Resilience Building Exercises, Journaling
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Medicine and Dentistry of New Jersey
Post COVID-19 Condition, Somatic Symptom Disorder
MR-spectroscopy in Post-covid Condition Prior to and Following a Yoga Breathing Intervention
From a clinical perspective, we find that many patients with Post COVID condition suffer from severe and debilitating shortness of breath, while routine pulmonary investigations fail to find the cause of the problems experienced.
- Trial name
- SpeCY (NCT05946512)
- Testing
- yoga, social contact
- Where
- Austria
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck
Myocardial Infarction
Safety Study of Bone Marrow Derived Cells to Treat Damaged Heart Muscle
Certain types of cells located in bone marrow may help the body recover after an injury. These cells may be able to help the body repair heart muscle that has been damaged from a heart attack.
- Trial name
- NCT00361855
- Testing
- NX-CP105
- Where
- 5 sites in United States
- Volunteers
- 18 people
- Sponsor
- Neuronyx