Clinical trials: Soft Contact Lenses
Refractive Errors
Clinical Performance of Two Daily Disposable Soft Contact Lenses
The purpose of this study is to compare the clinical performance of PRECISION1 contact lenses with Biotrue contact lenses.
- Trial name
- NCT05138783
- Testing
- Verofilcon A contact lenses, Nesofilcon A contact lenses
- Where
- 8 sites in United States
- Volunteers
- 129 people
- Sponsor
- Alcon Research
Presbyopia
A Clinical Comparison of Two Soft Multifocal Contact Lenses
The study objective was to gather short-term clinical performance data for two soft multifocal contact lenses.
- Trial name
- NCT05794126
- Testing
- Lens 1, Lens 2
- Where
- United Kingdom
- Volunteers
- 47 people
- Sponsor
- CooperVision, Inc.
Myopia
To Evaluate the Effectiveness of New Specially Designed Fitlens Soft Lens.
Myopia is a common disorder, affecting approximately one-third of the US population and over 90% of the population in some East Asian countries.
- Trial name
- NCT05433792
- Testing
- Myolens CN (Central-Near) soft contact lens, MiSight® soft contact lens
- Where
- Israel
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Fitlens Ltd.
Ametropia
A Clinical Study of the Comfilcon A Asphere Soft Contact Lens in Users of Digital Devices
The aim of this work is to investigate the clinical performance and subjective acceptance of the comfilcon A asphere contact lens when compared to single-vision spectacles in subjects who have never worn contact lenses and who…
- Trial name
- NCT04067050
- Testing
- comfilcon A asphere, Spectacles
- Where
- United Kingdom
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia
Acute Clinical Evaluation of Multi-purpose Solutions (MPS) in Soft Contact Lens Wearers
The purpose of this study was to clinically evaluate lens care solutions used with soft contact lenses.
- Trial name
- NCT00929487
- Testing
- Contact lens multi-purpose solution, Saline/blister pack solution, Contact lenses
- Where
- United Kingdom
- Volunteers
- 278 people
- Sponsor
- Alcon Research
Astigmatism, Myopia
Vision Stability and Preference for Soft Toric vs. Soft Spherical Contact Lenses
The principal hypothesis is to be tested in this work is that vision stability (the primary outcome measure) with a spherical contact lens correction vs. a toric contact lens correction will be the same.
- Trial name
- NCT04536571
- Testing
- Test Contact lens, Control Contact lens
- Where
- United Kingdom
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia, Myopia Progression
Contact Lenses to Slow Myopia Progression in Adults
Myopia (nearsightedness) can continue to worsen during young adulthood, increasing the risk of sight-threatening eye diseases later in life.
- Trial name
- NCT07747311
- Testing
- Dual Focus Soft Contact Lens, Single Vision Soft Contact Lens
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- University of California, Berkeley
Myopia, Accommodation
Dynamic Change in Accommodation After Wearing Multifocal Soft Contact Lenses for Myopia Control
The purpose of this study is to report the changes in accommodation, aberrations, and myopia in patients wearing multifocal soft contact lens for various durations. The study objectives are to: 1.
- Trial name
- NCT04763694
- Testing
- Multifocal soft contact lenses
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- State University of New York College of Optometry
Myopia, Refractive Errors
A Clinical Trial to Evaluate the Vision Correction Safety and Efficacy of DSiHy Silicone Hydrogel Soft Contact Lens
This is a prospective, randomized, double-blind, parallel, active-controlled, multi-center clinical study. The purpose is to evaluate the safety and effectiveness wearing "DSiHy Silicone Hydrogel Soft Contact Lens".
- Trial name
- NCT06716372
- Testing
- DSiHy Silicone Hydrogel Soft Contact Lens, Daily Silicone Hydrogel Contact Lenses (oB)
- Where
- 3 sites in Taiwan
- Volunteers
- 134 people
- Sponsor
- Visco Vision Inc.
Ametropia
Study of Soft Contact Lens Use With 7 Day Extended Wear
To compare the safety and efficacy of the CVI silicone-hydrogel lens worn on an extended wear basis for a period of up to 7 days and 6 nights with the Acuvue 2 soft contact lenses.
- Trial name
- NCT00597467
- Testing
- VISA (comfilcon A) Silicone Hydrogel Soft contact lens, Acuvue 2 Soft Contact Lens
- Where
- 23 sites in United States
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Visual Acuity
Evaluating Visual Acuity and Initial Fit Performance of Two Soft Contact Lenses
This is a multi-center, randomized, controlled, double-masked, 2x2 cross-over, non-dispensing study to compare visual acuity and lens fit performance.
- Trial name
- NCT04954833
- Testing
- EMO-200, EMO-118
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Contact Lens-induced Corneal Fluorescein Staining
Corneal Staining and Physiological Compromise After Eight Hours of Soft Contact Lens Wear
The purpose of this study is to assess corneal staining and to measure the relative corneal epithelial "barrier" function (the degree to which the cornea can prevent penetration of colored sodium fluorescein dye into the eye)…
- Trial name
- NCT01015768
- Testing
- ReNu Multiplus multipurpose disinfecting solution, Control
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Southern California College of Optometry at Marshall B. Ketchum University
Optometry
Smart Touch Non-dispensing Handling Studies
This study is a randomized, contralateral, investigator-masked non-dispensing study, to investigate the microbial contamination rates on the back surface of two types of soft contact lenses (hydrogel and silicone hydrogel)…
- Trial name
- NCT03253393
- Testing
- Smart Touch Technology packaging, Conventional lens packaging, EDTA
- Where
- Australia
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- The University of New South Wales
Myopia, Astigmatism
Prospective Study of an Investigational Toric Soft Contact Lens
The purpose of this study was to demonstrate substantial equivalence of an investigational toric soft contact lens to the commercially available Focus® DAILIES® Toric soft contact lens when worn in a daily wear, daily disposable…
- Conditions
- Myopia, Astigmatism, Refractive Error
- Trial name
- NCT01461811
- Testing
- Nelfilcon A toric contact lenses (with comfort additives), Nelfilcon A toric contact lenses
- Volunteers
- 154 people
- Sponsor
- CIBA VISION
Astigmatism
The Effect of the Changes in Cylinder Power and Axis of Toric Soft Contact Lenses on the Visual Quality, Satisfaction and Vision Acceptability in Astigmatic Subjects
Toric SCL combined spheric lens power with cylinder power and axis. However, in Indonesia, the availability of cylinder power and axis parameter variations between products are still narrow, with stock-keeping units (SKUs)…
- Trial name
- NCT06937489
- Testing
- Hydrogel conventional toric lenses with -10° axis misalignment, Hydrogel conventional toric lenses with +10° axis misalignment, Hydrogel conventional toric lenses with undercorrection of 0.5 D
- Where
- Indonesia
- Volunteers
- 20 people
- Sponsor
- Universitas Indonesia
Contact Lens Wear
Subjective Comfort With Multipurpose and Hydrogen Peroxide Lens Care Solutions in Soft Contact Lens Wearers
The purpose of this study was to assess comfort in soft contact lens wearers.
- Trial name
- NCT01164865
- Testing
- OPTI-FREE RepleniSH multipurpose disinfecting solution, Clear Care contact lens care system, Contact lenses
- Volunteers
- 78 people
- Sponsor
- Alcon Research
Myopia
Performance and Safety of Silicone Hydrogel Soft Contact Lenses
To demonstrate substantial equivalence of the new Silicone Hydrogel Soft Contact Lenses(SHSCL) to the commercially available ACUVUE® VITA™ contact lens
- Trial name
- NCT04226560
- Testing
- 41% Silicone Hydrogel Soft Contact Lenses(SHSCL), ACUVUE® VITA™ (senofilcon C) Brand (Soft) Contact Lens, Contact Lens Care Product
- Where
- Taiwan
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- ApexLens Co., Ltd.
Ametropia, Astigmatism
Comparison of Clinical Performance of Two Monthly Replacement Toric Soft Contact Lenses
The purpose of this study is to assess the clinical performance of TOTAL30 for Astigmatism (T30fA) soft contact lenses with Biofinity Toric soft contact lenses.
- Trial name
- NCT06165627
- Testing
- Lehfilcon A toric contact lenses, Comfilcon A toric contact lenses, CLEAR CARE
- Where
- 5 sites in United States
- Volunteers
- 67 people
- Sponsor
- Alcon Research
Myopia
Comparative Study to Evaluate the Cosmetic Appearance of Two Brands (Coopervision (CVI) vs. Competitor) of Color Soft Contact Lenses.
Comparative Study to Evaluate the Cosmetic Appearance of Two Brands (Coopervision (CVI) vs. Competitor)of Color Soft Contact Lenses
- Trial name
- NCT02299869
- Testing
- Verde (Competitor-control), Green (CVI-test), Cinza (Competitor-control)
- Where
- Mexico
- Volunteers
- 41 people
- Sponsor
- CooperVision, Inc.
Presbyopia
Extended Depth of Focus Contact Lenses for Presbyopia
VTI has an FDA cleared soft contact lens product. Its optical design creates an enhanced depth of focus (EDOF), which provides clear distance, intermediate, and near vision.
- Trial name
- NCT05495971
- Testing
- NaturalVue Multifocal
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Visioneering Technologies, Inc