Clinical trials: Sodium-sensitivity
Dry Eye Syndromes, Lubricant Allergy
Safety and Tolerability of PRO-087 Versus Xyel Ofteno® and Systane Ultra®, on the Ocular Surface of Healthy Subjects
Phase I clinical study, to evaluate the safety and tolerability of the preservative-free ophthalmic solution PRO-087 versus Xyel Ofteno® and Systane Ultra®, on the ocular surface of ophthalmological and clinically healthy…
- Conditions
- Dry Eye Syndromes, Lubricant Allergy, Tear Disorder
- Trial name
- PRO-087/I (NCT03524157)
- Testing
- PRO-087, Systane Ultra, Xyel Ofteno
- Where
- Mexico
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Laboratorios Sophia S.A de C.V.
Allergy
Neo-Synalar Modified 48 Hour Patch Test
A 48 hour patch test performed in healthy volunteers to determine the presensitization (pre-existing allergy) of Neo-Synalar (neomycin sulfate 0.5%(0.35% neomycin base), fluocinolone acetonide 0.025%) Cream .
- Trial name
- NCT02168478
- Testing
- Neo-Synalar Cream, Sodium Lauryl Sulfate Aqueous Solution (0.40%), Saline
- Where
- United States
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- Noah Rosenberg, MD
Salt Sensitivity of Blood Pressure, Hypertension
CARDIA-Salt Sensitivity of Blood Pressure (SSBP)
Salt sensitivity of blood pressure (SSBP) is defined as the change in blood pressure (BP) in relation to change in salt intake. An increase in BP from low- to high-salt diet is common and associated with an increased risk of…
- Trial name
- NCT04258332
- Testing
- High Salt Diet, Low Salt Diet
- Where
- 2 sites in United States
- Volunteers
- 281 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Salt Sensitivity of Blood Pressure
Central Sodium Sensing: Implications for Blood Pressure Regulation
The ability of the brain to sense changing sodium levels in the blood is critical in mediating the neurohumoral responses to hypernatremia, however, the mechanisms underlying sodium sensing in humans is poorly understood.
- Trial name
- NCT05480722
- Testing
- Hypertonic Saline with furosemide, Hypertonic Saline without furosemide
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Dentin Sensitivity
A Clinical Study to Evaluate the Anti-Sensitivity Effect of a Calcium Sodium Phosphosilicate Toothpaste in a Population of Dentin Hypersensitivity Sufferers
The aim of this study is to confirm the clinical dentin hypersensitivity (DH) efficacy of a 5 percent (%) calcium sodium phosphosilicate (CSPS) toothpaste.
- Trial name
- NCT06378008
- Testing
- CSPS toothpaste, Regular fluoride toothpaste (Crest Cavity Protection)
- Where
- Canada
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- HALEON
Dentin Hypersensitivity
A Comparison Study of Hypersensitivity Treatment
The goal of this clinical trial is to evaluate the effect of 3M™ Clinpro™ Fluoride Aqueous Solution (experimental) on Dentin Hypersensitivity (DHS) in comparison to 3M™ Vanish™ (commercialized, control] in patients who have DHS.
- Trial name
- NCT05768373
- Testing
- 3M™ Clinpro™ Fluoride Aqueous Solution, 3M™ Vanish™
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Solventum US LLC
Hypertension
The Role of COX-2 Inhibition in Salt Sensitivity of Blood Pressure
The purpose of this study is to determine if the drug Celebrex changes the way the kidney gets rid of salt and maintains blood pressure.
- Trial name
- NCT00624559
- Testing
- celecoxib (Celebrex)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Dentin Sensitivity
Clinical Efficacy in Relieving Dentin Hypersensitivity of Nanohydroxyapatite-Containing Toothpastes and Cream
This study will investigate the effectiveness of nanohydroxyapatite (nano-HAP)-containing toothpastes and cream to relieve dentin hypersensitivity, comparing it with those of a commercial desensitizing dentifrice containing…
- Trial name
- NCT02918617
- Testing
- Control toothpaste containing Novamin® technology, Control toothpaste containing 1500 ppm fluoride as MFP, Test toothpaste with nano-HAP (high concentration)
- Where
- United States
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio