Clinical trials: Socket Preservation
Alveolar Bone Resorption, Wound Heal
Alveolar Socket Healing With and Without PRGF
A single-centre randomised controlled pilot study involving 12-24 healthy adult patients for investigating dental extraction socket healing with and without plasma rich in growth factors (PRGF) taking place during early days of…
- Trial name
- NCT04383158
- Testing
- PRGF ENDORET® obtained from ENDORET® POST-EXTRACTION ALVEOLUS DENTAL KIT (KMU16)
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Socket Preservation
Socket Preservation After Surgical Extraction of Impacted Lower Third Molar
The aim of this study will be to evaluate socket preservation using autogenous particulate dentin in combination with liquid platelet-rich fibrin versus bone allografts and collagen cone after surgical extraction of the…
- Trial name
- NCT06716736
- Testing
- socket preservation using dentine graft mixed with i-PRF, socket preservation using bone allograft, socket preservation using collagen cone
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Wael Mohamed
Socket Preservation, Alveolar Ridge Preservation
Evaluation of the Effectiveness of the Socket Preservation Technique Using Allogeneic and Xenogeneic Materials
Tooth extraction is among the most common dental treatments. The procedure results in the formation of a bone defect. During the healing phase, the vertical and horizontal diameters of the alveolar ridge decrease, which has a…
- Conditions
- Socket Preservation, Alveolar Ridge Preservation, Xenograft, Allograft
- Trial name
- NCT07565558
- Testing
- Socket preservation with xenograft, Socket preservation with allograft
- Where
- 2 sites in Poland
- Volunteers
- 40 people
- Sponsor
- Medical University of Silesia
Oral Soft Tissue Conditions
A Comparative Clinical Study Between a Collagen Matrix and Collagen Membrane as Wound Protection During Ridge Preservation ARP
Patients in need of extraction of two teeth in combination with alveolar ridge preservation will be invited to participate in intra-subject RCT on ARP. Prior to surgery, a small-field low-dose CBCT is taken.
- Trial name
- ARP (NCT06029322)
- Testing
- Socket seal after alveolar ridge preservation
- Where
- Belgium
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Socket Preservation
Sticky Bone vs Xenograft With Cross-linked Hyaluronic Acid in Socket Preservation
The present study aimed to evaluate clinical and radiographic outcomes of sticky bone in comparison to crosslinked hyaluronic acid mixed with xenograft in alveolar ridge preservation.
- Trial name
- NCT06983015
- Testing
- sticky bone, xenograft mixed with cross-linked hyaluronic acid
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Alveolar Bone Atrophy
Effect of Socket Preservation Procedure on Dimensional Changes of the Ridge, and Its Efficacy.
In this study, the investigators will evaluate the dimensional changes of alveolar bone in the preserved sites in comparison with extraction only conventional healed sockets, as well. 1.
- Trial name
- NCT01268982
- Testing
- socket preservation
- Where
- Iran
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Mashhad University of Medical Sciences
Teeth Extraction, Tooth Socket
Implant Placement in the Preserved Socket Using Socket Shield Technique With Autogenous Dentin Graft Versus Preserved Socket Using Socket Shield With Alloplast
Alveolar bone resorption and labial bone plate reduction follow teeth extraction due to the deficiency of blood supply, derived from the loss of periodontal ligaments, and hence the socket shield technique with Bone graft was…
- Trial name
- NCT05047861
- Testing
- socket shield technique with autogenous dentin graft, socket shield technique with alloplast graft
- Where
- Egypt
- Volunteers
- 8 people
- Sponsor
- Hams Hamed Abdelrahman
Clinical Efficacy
Ridge Preservation Comparing an Intrasocket Graft Alone to an Intrasocket Graft Plus a Facial Overlay Graft
The purpose of this study is to compare two methods of ridge preservation in the maxillary anterior esthetic zone to determine the best method to establish adequate bone and soft tissue to accommodate implant placement.
- Trial name
- NCT01431131
- Testing
- Intrasocket graft, Intrasocket plus facial overlay graft
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Alveolar Ridge Augmentation
Vallomix Socket Preservation Study
This research aims to compare the effectiveness of two bone grafting materials on preserving jawbone integrity after tooth extraction.
- Trial name
- NCT06472453
- Testing
- Allograft/Xenograft, Allograft
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Periodontology, Oral Surgery
Case Series of New Alloplastic Bone Graft Material
A case series to compare the handling and effectiveness of two different treatment approaches using a new alloplastic bone graft material in ridge preservation compared to allograft existing historical data.
- Trial name
- NCT02221557
- Testing
- easy-graft (beta-Tricalcium Phosphate)
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Sunstar Americas
Socket Preservation, Implant-supported Single Crowns
Hyaluronic Acid and Polynucleotides in Ridge Preservation
The aim of this study is to test the use of a bovine-derived bone graft combined with a polynucleotides-rich hyaluronic acid (PNHA) gel for the preservation of the bone after a tooth extraction (alveolar ridge preservation) and…
- Conditions
- Socket Preservation, Implant-supported Single Crowns, Hyaluronic Acid, CAD-CAM
- Trial name
- P-005 (NCT07099846)
- Testing
- regeneration of post extraction socket with biomaterials
- Where
- 2 sites in Italy
- Volunteers
- 40 people
- Sponsor
- University of Parma
Socket Preservation
Bone Material's Histomorphometric Analysis In Socket Preservation
This is a prospective, multicentre, parallel-group, randomized controlled, single blinded (participant) trial aims to compare the investigational medical device with standard of care in dental treatment addressing the…
- Trial name
- BM-HIS-SP (NCT06740110)
- Testing
- Tooth extraction and GBR procedure
- Where
- 4 sites in Poland
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Medical Inventi S.A.
Socket Preservation
The Effectiveness of Hyaluronic Acid in Bone Regeneration
Bone loss due to resorption is commonly observed in the alveolar socket following tooth extraction. This situation makes it difficult to preserve sufficient bone volume that would allow for ideal implant placement in cases…
- Trial name
- socket healing (NCT07031895)
- Testing
- a bovine-derived graft/xenograft enriched with hyaluronic acid, a standart bovine-derived graft/xenograft
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Alveolar Bone Loss, Tooth Loss / Rehabilitation
Bone and Soft Tissue Healing After Socket Preservation With NOVAMag or Permamem Membranes
After tooth extraction, the surrounding bone and soft tissue may undergo dimensional reduction. Socket preservation involves placement of a bone graft into the extraction socket and coverage with a membrane to support healing…
- Conditions
- Alveolar Bone Loss, Tooth Loss / Rehabilitation, Alveolar Bone Grafting, Socket Preservation
- Trial name
- NCT07856693
- Testing
- NOVAMag Membrane, permamem Membrane, Alveolar Socket Preservation With an Allogeneic Bone Graft
- Where
- Croatia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
Bone Regeneration, Bone And Bones
Effects of Autogenous Dentin Graft on Socket Preservation
Various graft materials are used to reconstruct bone defects in the jaws due to tooth loss, trauma, advanced periodontal diseases, pathological lesions and congenital disorders.
- Conditions
- Bone Regeneration, Bone And Bones, Bone Substitutes
- Trial name
- NCT04131894
- Testing
- autogenous dentin graft, platelet rich fibrin (PRF)
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Tooth Extraction Status Nos, Edentulous Alveolar Ridge
3D Radiographic Evaluation of a Novel Implant Site Development Technique
The present retrospective study aims at assessing the clinical effects of a novel implant site development (Extraction site development - XSD) technique after tooth extraction compared with extraction alone in patients requiring…
- Trial name
- NCT02660697
- Testing
- Extraction site development
- Where
- Hungary
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Alveolar Socket Preservation
Post Extraction Changes After Alveolar Socket Preservation Using Autogenous Dentin Graft (ADG) Combined With Either Albumin Platelet-rich Fibrin (ALB-PRF) or Standard Platelet-rich Fibrin (PRF).
The study focuses on the impact of tooth loss on alveolar bone, which shrinks significantly within the first three months. To prevent this, strategies like alveolar ridge preservation are used.
- Trial name
- Alb-PRF (NCT06757218)
- Testing
- empty socket, Autogenous Dentin Graft with Platelet Rich Fibrin, Autogenous Dentin Graft with Albumin Platelet Rich Fibrin
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kafrelsheikh University
Xenograft Model
Xenograft and Posterior Mandibular Socket Filling
The aim of this study is to evaluate the volume of madibular bone after placement of a xenograft in a fresh extraction socket in human.
- Trial name
- Flapless (NCT02736773)
- Testing
- xenograft material to slow resorption
- Where
- France
- Volunteers
- 35 people
- Sponsor
- University Hospital, Montpellier
Alveolar Bone Loss, Pathological Conditions, Anatomical
Comparison of Amnion Chorion Membrane vs. Dense Polytetrafluoroethylene Membrane in Ridge Preservation Procedures
The purpose of this study is to examine if a biologically active commercially available amnion chorion membrane (ACM) is as effective as the commercially available inert dense polytetrafluoroethylene membrane (D-PTFE) in…
- Trial name
- NCT02602223
- Testing
- Placing Amnion chorion membrane over grafted site, Placing d-PTFE membrane over grafted site
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Indiana University
Alveolar Ridge Preservation
Polynucleotide-Hyaluronic Acid Gel With Xenograft for Alveolar Ridge Preservation
This randomized controlled clinical trial will evaluate the efficacy of polynucleotide-hyaluronic acid gel combined with xenograft and collagen membrane for alveolar ridge preservation following tooth extraction.
- Trial name
- NCT07771257
- Testing
- Polynucleotide-Hyaluronic Acid Gel With Xenograft, Xenograft With Collagen Membrane
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University