Clinical trials: Social Isolation
Aging, Mild Cognitive Impairment
Enhancing Quality of Life for Older Adults With and Without Mild Cognitive Impairment (MCI) Through Social Engagement Over Video Technology
The goal of this randomized controlled trial is to rigorously assess the efficacy of an 8-week social engagement OneClick intervention.
- Conditions
- Aging, Mild Cognitive Impairment, Aging Well
- Trial name
- NCT05380180
- Testing
- OneClick Social Engagement Intervention, OneClick Social Engagement Intervention Extension
- Where
- 2 sites in United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Depression
Teen Brain Online II: Understanding How Social Media Affects the Teen Brain
There has been much interest in the potential role of social media (SM) use in driving a current mental health crisis among teens, with a dire need for evidence that goes beyond self-report.
- Trial name
- TBO-II (NCT06817993)
- Testing
- Rejection and Acceptance Feedback
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Pittsburgh
Psychotic Disorders, Hallucinations, Auditory
Testing a Peer-Support Group for Veterans Who Hear Voices
Veterans with schizophrenia spectrum disorders who experience psychosis struggle with social integration- e.g., participation in work, housing, and citizenship-due to symptoms, stigma, and psychosocial functioning deficits.
- Conditions
- Psychotic Disorders, Hallucinations, Auditory, Social Isolation
- Trial name
- VVV RCT (NCT07555275)
- Testing
- Veteran Voices and Visions (VVV), Wellness Recovery Action Planning (WRAP)
- Where
- 2 sites in United States
- Volunteers
- 160 people
- Sponsor
- VA Office of Research and Development
Healthy Adults, High Altitude
Human Milk Oligosaccharides (HMOs) and Gut Microbiota, Immune System in Antarctica
Human milk oligosaccharides (HMOs) are the third-most abundant component in mothers' milk and are an important prebiotic factor for the development of the gut microbiota of infants, promoting the growth of certain beneficial…
- Conditions
- Healthy Adults, High Altitude, Isolation, Social
- Trial name
- NCT06133530
- Testing
- Human milk oligosaccharides, Maltose
- Where
- Germany
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- IU University of Applied Sciences
Social Isolation, Loneliness
Keep Social Study for Young Adults
The Keep Social randomized control trial (RCT) is a 6-week, online study which will test whether, relative to a placebo control condition, an intervention that encourages high-quality in-person social interactions with strangers…
- Trial name
- KSSYA (NCT07005817)
- Testing
- Experimental Health Communication, Simulated Social Media Platform Only
- Where
- United States
- Volunteers
- 1,900 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Social Isolation in Older Adults, Loneliness
An Innovative App-based Intervention to Promote Social Connectedness and Well-being in Older Adults
This study evaluates the impact of a group-based intervention designed to promote social connectedness and enhance psychological well-being among older adults.
- Trial name
- VITA (NCT07443813)
- Testing
- Blended VITA intervention (hybrid app-based and in-person social engagement program)
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Padova
Osteoarthritis, Osteoarthritis (OA) of the Knee
Feasibility of Choose to Move Replacement Ready
Choose to Move (CTM) is a 3-month, choice-based health-promoting program for low active older adults being scaled-up across British Columbia (BC), Canada.
- Conditions
- Osteoarthritis, Osteoarthritis (OA) of the Knee, Osteoarthritis, Hip, Total Knee Arthroplasty; Total Hip Arthroplasty
- Trial name
- CTM-RR (NCT07069179)
- Testing
- Choose to Move Replacement Ready
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of British Columbia
Social Isolation, Health Services Accessibility
Optimizing Medical Decisions and Care for Adult Orphans
This study aims to evaluate the effectiveness of a training program designed to improve clinicians' ability to care for adult orphans.
- Trial name
- NCT07465770
- Testing
- Caring for Adult Orphans
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chang Gung University
Schizophrenia and Related Disorders
Social Isolation and Aging in Schizophrenia
Individuals diagnosed with schizophrenia and related psychotic disorders (SZ) exhibit a markedly elevated risk of premature mortality, with a 10-20-year shorter lifespan relative to the general population.
- Trial name
- SIAS (NCT07419321)
- Where
- 4 sites in United States, Netherlands and 2 more
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Substance Use Disorders
Substance Use and Loneliness
Background: Loneliness-a subjective emotional state characterized by the perception of social isolation-is a psychosocial factor that is associated with increased mortality, substance use, and is associated with precipitants of…
- Trial name
- NCT05338268
- Testing
- CBT for Loneliness, CBT for Substance Use Disorder
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- VA Office of Research and Development
Social Isolation, Loneliness
Culture and Well-Being for Latinos
The proposed K23 study is an intervention study using an experimental therapeutics approach. This pilot RCT asks: "Does SOCIAL-ENGAGE increase cultural-social engagement and decrease suicide risk among Spanish-speaking adults?"…
- Conditions
- Social Isolation, Loneliness, Suicidal Ideation
- Trial name
- NCT05244733
- Testing
- Social Engage (S-ENGAGE), The Healthy Lifestyles Education Program
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of Rochester
Loneliness, Social Isolation
Need to be Needed (N2BN) Intervention
The proposed study is a randomized, controlled trial (RCT) that will examine the effectiveness of an intervention designed to reduce social isolation and loneliness of adults with serious mental illness (SMI).
- Trial name
- N2BN RCT (NCT06510439)
- Testing
- Need to Be Needed Intervention, Active Control Group
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Temple University
Professional Fulfillment, Burnout
Commensality Groups: A Professional Fulfillment Intervention for Medical Students in Their Clinical Years
Medical students are at high risk for burnout, depression, anxiety, suicidal ideation and substance use disorder with burnout seen as a mitigating factor for suicidal ideation.
- Conditions
- Professional Fulfillment, Burnout, Social Isolation or Loneliness
- Trial name
- NCT06656650
- Testing
- Commensality groups
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Hypopituitarism, Central Diabetes Insipidus
Identification and Clinical Relevance of an Oxytocin Deficient State (GLP1 Study)
Oxytocin (OT) is a hypothalamic peptide that enters the peripheral circulation via the posterior pituitary gland. OT plays a key role in regulating appetite, psychopathology, prosocial behavior and sexual function.
- Conditions
- Hypopituitarism, Central Diabetes Insipidus, Panhypopituitarism, Psychological Disorder
- Trial name
- NCT04897802
- Testing
- Experimental: GLP1-RA (exenatide) administration
- Where
- Spain
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Substance Use Disorder (SUD)
The Effect of Cognitive Behavioral Model-Based Psychoeducation on Social Exclusion, Hopelessness, and Relapse Levels in Individuals Diagnosed With Substance Use Disorder
This research was planned to measure the effect of cognitive behavioral model-based psychoeducation on the level of social exclusion and hope in individuals diagnosed with substance use disorder, as well as teaching them to cope…
- Trial name
- NCT07316335
- Testing
- Cognitive Behavioral Therapy (CBT) Theoretical Basic Training Group
- Volunteers
- 44 people
- Sponsor
- Ataturk University
Social Isolation, Loneliness
Study 1: Social Engage Coaching R61 Phase
The purpose of this study is to test whether an individual coaching program called Social Engage Coaching (or 'Engage Coaching' for short) helps adults age 60 and older feel more connected to other people in ways that matter to…
- Conditions
- Social Isolation, Loneliness, Suicide Ideation, Quality of Life
- Trial name
- R61 Phase (NCT05745493)
- Testing
- Social Engage Coaching (S-ENG)
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- University of Rochester
Chronic Pain
Pain and Loneliness
Loneliness-feeling socially isolated-is a stressor that is associated with chronic pain. The investigators will first conduct a small trial of Cognitive Behavioral Therapy for Loneliness (CBT-L)in Veterans with chronic pain…
- Trial name
- NCT05455476
- Testing
- CBT for Loneliness, CBT for Chronic Pain
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- VA Office of Research and Development
Nutrition Poor, Physical Inactivity
Digital Nutrition Intervention for Older Adults
The "digital divide" or gap in technological access and knowledge, for older adults has worsened during the COVID-19 pandemic, leading to disruptions in services like congregate meal programs funded by the Older Americans Act.
- Conditions
- Nutrition Poor, Physical Inactivity, Social Isolation
- Trial name
- NCT05220631
- Testing
- Technology intervention, Digital Nutrition Intervention
- Where
- United States
- Volunteers
- 369 people, healthy volunteers welcome
- Sponsor
- The University of Texas at San Antonio
Urinary Incontinence
PURI-PRO - Symptoms Impact and eHealth Intervention for Menopausal Women With Urinary Incontinence
Urinary Incontinence (UI) is a public health problem that disrupts the Quality of Life, Productivity, Social Isolation and Sexual Function; its prevalence in peri- and postmenopausal women is around 30-40%.
- Trial name
- PURI-PRO (NCT06527638)
- Testing
- Experimental Group: eHealth intervention for UI symptoms improvement, Control Group: Delivery of a Health Literacy single-leaflet
- Where
- Portugal
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- ISPA - Instituto Universitario de Ciencias Psicologicas, Sociais e da Vida
Opioid Use Disorder, Loneliness
Intervening on Opioid Use and Loneliness
This study aims to enroll 300 participants who will be assigned to one of three 3 groups. Each group will receive an intervention lasting 6, weekly sessions of 40-60 minutes.
- Conditions
- Opioid Use Disorder, Loneliness, Social Isolation
- Trial name
- NCT06458335
- Testing
- Cognitive-Behavioral Therapy for Perceived Social Isolation, Health Education
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Rochester