Clinical trials: Smoking Behaviors
Chronic Diseases
Longitudinal Care: Smoking Reduction to Aid Cessation
The purpose of this study is to determine whether an extended care treatment model lasting over a year will increase long-term smoking cessation rates compared to the standard 8 week treatment of care.
- Trial name
- NCT00309296
- Testing
- smoking cessation
- Where
- United States
- Volunteers
- 443 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health (NIH)
Vaping
Responses to Message Source and Presentation Using Psychophysiology
The goal of this clinical trial is to use psychophysiological methods to test the effects of a message source (expert and peer) and message presentation types (one-sided and two-sided) to identify the optimal message type for…
- Trial name
- NCT06269003
- Testing
- Expert, one-sided, Expert, two-sided, Peer, one-sided
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Colorectal Cancer, Early Onset Colorectal Cancer
Exogenous and Endogenous Risk Factors for Early-onset Colorectal Cancer
An increase in early-onset colorectal cancers (eoCRC), defined as a CRC before 50 years, is confirmed globally. CRC pathogenesis has been associated with several risk factors (family history, germline pathogenic variants…
- Conditions
- Colorectal Cancer, Early Onset Colorectal Cancer, Diet Habit, Risk Reduction
- Trial name
- DEMETRA (NCT05732623)
- Testing
- Semi Quantitative Food Frequency Questionnaire (SQFFQ)
- Where
- 8 sites in United States, Finland and 4 more
- Volunteers
- 2,300 people, healthy volunteers welcome
- Sponsor
- San Raffaele University
Smoking &Amp; Tobacco Cessation
An Innovative Conversational Agent (Quitbot) for Smoking Cessation
This phase III trial compares two remote digital smoking cessation programs to see how well they work for quitting smoking.
- Trial name
- NCT04308759
- Testing
- Experimental Smoking Cessation Program, Control Smoking Cessation Program
- Where
- United States
- Volunteers
- 1,647 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Smoking Cessation, Tobacco Use Disorder
Effectiveness of the Nicotine Patch in Suppressing Nicotine Withdrawal Symptoms in Women Versus Men - 1
Women typically have a more difficult time quitting smoking than men. Little research has been done to understand the differences between men and women that may cause this distinction.
- Trial name
- NCT00218140
- Testing
- nicotine transdermal system
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Tobacco Smoking
Cognitive and Emotional Skills to Aid Smoking Prevention
The purpose of the current proposal is to investigate the extent to which interventions designed to improve cognitive (working memory) and emotional (distress tolerance) regulatory processes enhance the effectiveness of standard…
- Trial name
- DOAN (NCT03058991)
- Testing
- Distress Tolerance Intervention, Working Memory Intervention, Control Informational Intervention
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Smoking Cessation
Cigarette Pack Inserts for Smoking Cessation
This study will test whether cigarette package inserts (i.e., small printed leaflets inside cigarette packs) with messages about the benefits of cessation and tips for quitting can help smokers quit.
- Trial name
- NCT04075682
- Testing
- Inserts with efficacy messages, Pictorial warnings on packs
- Where
- 2 sites in United States
- Volunteers
- 387 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Smoking
Risk Perception Among Quitting Smokers
The goal of this behavioral research study is to put together and study a treatment for nicotine dependence that looks at how participant's thoughts and feelings about smoking may be related to how successfully they quit smoking.
- Trial name
- NCT00384696
- Testing
- Nicotine Replacement Therapy, Questionnaire
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Adolescent Substance Use
Guiding Good Choices for Health
This study evaluates the feasibility and effectiveness of implementing Guiding Good Choices (GGC), an anticipatory guidance curriculum for parents of early adolescents, in three large, integrated healthcare systems.
- Trial name
- GGC4H (NCT04040153)
- Testing
- Guiding Good Choices
- Where
- 3 sites in United States
- Volunteers
- 3,636 people, healthy volunteers welcome
- Sponsor
- University of Washington
Periodontitis, Dual- Light Photodynamic Therapy
Use of Dual-light Photodynamic Therapy as an Adjunct to Periodontal Treatment in Smokers
The goal of this controlled clinical trial is to investigate the impact of regular home use of Lumoral device as an adjunct treatment compared to non-surgical periodontitis treatment (NSPT) alone on biofilm removal and host…
- Conditions
- Periodontitis, Dual- Light Photodynamic Therapy, Smoking, Cigarette, Non-surgical Periodontal Therapy
- Trial name
- NCT05962801
- Testing
- Lumoral device, Lumorinse
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Tobacco Use Cessation
Comparative Effectiveness of Mobile Health Smoking Cessation Approaches Among Underserved Patients in Primary Care
This study will evaluate the comparative effectiveness of three smoking cessation therapies: mobile health (mHealth) application iCanQuit, mHealth application iCanQuit + Motiv8, and the Florida quit line.
- Trial name
- PROMOTE-UP (NCT05415761)
- Testing
- iCanQuit, iCanQuit+Motiv8, Florida quit line
- Where
- United States
- Volunteers
- 1,332 people, healthy volunteers welcome
- Sponsor
- University of Florida
Peri-Implantitis, Peri-implant Mucositis
Association Between Smoking Habit and Peri-implant Diseases: a Case Control Study
Although smoking has been proposed as well, as a risk factor/indicator for peri-implantitis, there is currently no conclusive evidence. The current literature confronts the inconclusive evidence of tobacco for a risk factor.
- Conditions
- Peri-Implantitis, Peri-implant Mucositis, Bone Loss, Alveolar
- Trial name
- NCT04952428
- Testing
- Re-examination visit ("today visit")
- Where
- Spain
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Tobacco Use Disorder
Persistence-Targeted Smoking Cessation
The investigators propose to develop a theory-based smoking cessation intervention (called Persistence-targeted smoking cessation; PTSC).
- Trial name
- PTSC (NCT01654107)
- Testing
- Persistence Targeted Smoking Cessation, Clearing The Air, Nicotine lozenge
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Smoking, Healthy Volenteers
Evaluation of GCF MMP-1, -8 and Growth Factor Levels in Smokers With Periodontal Health
Increased levels of cytokines in GCF have been demonstrated in smoker subjects with chronic periodontitis. It is not surprising that increased levels of inflammation associated molecules in GCF has been observed in smokers with…
- Trial name
- NCT02014857
- Testing
- Gingival Crevicular Fluid Sampling
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Ege University
Tobacco Dependence
Comparisons of Nicotine-free Cigarettes, Extra Low Nicotine Cigarettes vs. Medicinal Nicotine
In this study, smokers will be randomly assigned to one of three conditions for six weeks: 1) nicotine-free cigarettes (0.05mg); 2) extra low nicotine cigarettes (0.3 mg); or 3) medicinal 4 mg nicotine lozenge.
- Trial name
- NCT00777569
- Testing
- Nicotine free cigarettes, Extra-low nicotine cigarettes, Nicotine Lozenge
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Nicotine, Nicotine Vaping
Developing E-liquid Product Standards (Sweet Spot Study)
The Sweet Spot Study aims to evaluate the effect of e-liquids with nicotine varying in freebase (FB) levels and concentrations on the appeal of electronic cigarettes (ECs) in young adult EC users with minimal/no history of…
- Conditions
- Nicotine, Nicotine Vaping, E-cigarette Use
- Trial name
- NCT05864586
- Testing
- Vaping study EC A, Vaping study EC B, Vaping study EC C
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Inflammation, Smoking Cessation
Screening and Multiple Intervention on Lung Epidemics
This prospective randomized pilot trial will evaluate a multiple intervention program of prevention in lifelong smokers aiming at reduction of chronic inflammation status through treatment with low-dose acetylsalicylic acid…
- Conditions
- Inflammation, Smoking Cessation, Diet Modification, Physical Activity
- Trial name
- SMILE (NCT03654105)
- Testing
- Cytisine, Acetylsalicylic acid, Diet Modification and Physical Activity Increase
- Where
- Italy
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Hookah Smoking
Effects of Hookah (Waterpipe) Smoking on Blood Vessel Function
The purpose of this study is to assess the acute effects of Hookah (waterpipe) smoking on blood vessel function. Hookah smoking has been shown to immediately increase blood pressure and heart rate which could result in damage in…
- Trial name
- NCT03616002
- Testing
- Hookah smoking
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Smoking Cessation, Smoking, Cigarette
Preloaded Combination Nicotine Replacement Therapy on Smoking Cessation of Adult Population in Kazakhstan
Randomized, controlled, two-armed, single-blinded, superiority trial with 1:1 allocation ratio Nicotine Replacement Therapy(NRT)
- Conditions
- Smoking Cessation, Smoking, Cigarette, Smoking Behaviors
- Trial name
- NCT05484505
- Testing
- Nicotine patch, Nicotine gums, Brief Advice (5 A's & 5 R's), Nicotine Patch: Preloading for 4 weeks
- Where
- 2 sites in Kazakhstan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Nazarbayev University
Smoking Cessation
Safety and Efficacy Study of the NRT CQSS2 System for Smoking Cessation in Treatment-Seeking Subjects
Transdermal nicotine delivery systems are a cigarette smoking cessation aid designed to deliver nicotine into the systemic circulation via the skin.
- Trial name
- NCT03178422
- Testing
- CQSS2, NicoDerm CQ Patch
- Where
- 5 sites in United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Chrono Therapeutics, Inc.
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