Clinical trials: Smoking ( Cigarette)
Tobacco Use Disorder
Innovative Interventions for Smoking Cessation
The purpose of this study is to evaluate the effect of a combination of the 21 mg nicotine patch and very low nicotine content (VLNC) cigarettes compared to 21 mg nicotine patch only and very low nicotine content cigarette only…
- Trial name
- NCT01050569
- Testing
- Nicotine Patch, VLNC Cigarette, VLNC Cigarette Plus Nicotine Patch
- Where
- 2 sites in United States
- Volunteers
- 235 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Cigarette Smoking
Serbian Smoking Reduction/Cessation Trial (2SRT)
The study aims to establish if a low-nitrosamine, smokeless tobacco product (Swedish snus) can help adult smokers to reduce and eventually completely quit smoking.
- Trial name
- 2SRT (NCT00601042)
- Testing
- Swedish snus (smokeless tobacco), Onico
- Where
- 2 sites in Serbia
- Volunteers
- 319 people, healthy volunteers welcome
- Sponsor
- Swedish Match AB
Cigarette Smoking Behavior
Nicotine Reinforcement and Smoking-Cue Reactivity: Association With Genetic Polymorphisms
In this study, potential associations between several genetic polymorphisms and nicotine dependence will be examined. The relative reinforcing efficacy of cigarettes using the forced-choice procedure will be assessed.
- Trial name
- NCT02921282
- Testing
- Genotype dopamine, Genotype cannabinoids
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Vaping, E-cigarette Use
PACE Vape Messaging Study
The purpose of this study is to examine the effect of exposure to vape education messages on beliefs, perceptions, norms, and behaviors related to electronic vapor product use.
- Conditions
- Vaping, E-cigarette Use, Electronic Cigarette Use
- Trial name
- NCT04450537
- Testing
- Vape Messaging Intervention
- Where
- United States
- Volunteers
- 569 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Smoking
Investigate the Exposure to Selected Smoke Constituents in Smokers Switching to Distillation Based Smoking Article
The overall purpose of this clinical study conducted in confinement under well-defined conditions is to obtain initial data on the levels of human body exposure to selected smoked constituents of the SMAR cigarette.
- Trial name
- NCT00812279
- Testing
- Distillation based smoking article (SMAR cigarette), conventional cigarette, smoking cessation
- Where
- Poland
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Lung Inflammation, HIV Seropositivity
Effects of E-cigarettes (ECIGs) on Pulmonary Inflammation and Behavior in HIV Infected Smokers
The purpose of this study is to determine if using e-cigarettes (ECIG) rather than regular tobacco cigarettes alters lung inflammation in people with and without HIV.
- Trial name
- NCT02848586
- Testing
- ECIGS, mobile contingency management (mCM), Usual brand
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Duke University
Smoking
Young Adults and Low Nicotine Cigarettes
The purpose of this study is to look at the effects of investigational low nicotine cigarettes on young adult smokers. The investigators are interested in how using these products affects young adults' perceptions and smoking…
- Trial name
- YLP (NCT03699865)
- Testing
- Nicotine content
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Abramson Cancer Center at Penn Medicine
Smoking
Reduced Exposure Study Using THS 2.2 Menthol With 5 Days in a Confinement Setting Followed by 86 Days in an Ambulatory Setting
Evaluate if the ad libitum use of the THS 2.2 Menthol (mTHS), a candidate Modified Risk Tobacco Product, for 5 days in confinement, and after 86 days in an ambulatory setting, by apparently adult healthy smokers results in a…
- Trial name
- NCT01989156
- Testing
- THS 2.2 Menthol (mTHS 2.2), Menthol Conventional Cigarette (mCC), Smoking Abstinence (SA)
- Where
- 2 sites in United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Tobacco; Use, Harmful
The Influence of Electronic and Traditional Cigarettes Smoking on Hemodynamic Parameters
It is intended to examine 50 healthy volunteers aged 18 - 60 years. 12-hour abstinence from tobacco smoke, alcohol or coffee before the experiment will be required.
- Trial name
- EPAPHemo (NCT03037775)
- Testing
- Baseline, e-cigarette without nicotine, e-cigarette with nicotine
- Where
- Poland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Smoking, Smoking Habit
PRogetto Salute Parma
This project from the University Hospital of Parma (AOUPR) aims to verify the feasibility of a prevention program in our district, relying on advanced technological resources and highly experienced team in lung cancer early…
- Conditions
- Smoking, Smoking Habit, Smoking, Tobacco, Smoking, Cigarette
- Trial name
- PSP (NCT04282694)
- Testing
- Low-dose computed tomography (LDCT)
- Where
- Italy
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Parma
Smoking ( Cigarette), Women
Smoking, Pain Threshold, and Hand Strength in Women
This study aims to investigate the effects of smoking on pain threshold, cervical position sense, and grip strength in women. Measurements will include pressure pain threshold (PPT), cervical position sense (CPS), grip strength…
- Conditions
- Smoking ( Cigarette), Women, Pain
- Trial name
- NCT07611760
- Testing
- observational study
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Substance Withdrawal Syndrome
Does Abstinence From E-cigarettes Produce Withdrawal Symptoms?
The purpose of this study is to see whether adults who use e-cigarettes every day experience symptoms of nicotine withdrawal when they stop using e-cigarettes for 6 days.
- Trial name
- NCT02825459
- Testing
- Abstinence from e-cigarettes
- Where
- 2 sites in United States
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Smoking Cessation
Cytisine and E-cigarettes With Supportive Text-messaging for Smoking Cessation (Cess@Tion)
This research focuses on maximizing the benefits of proven smoking cessation interventions to support people who smoke to quit, as part of the strategy to help New Zealand become smoke-free.
- Trial name
- Cess@Tion (NCT05311085)
- Testing
- Cytisine, Nicotine delivered via an e-cigarette, Cytisine plus nicotine delivered via an e-cigarette
- Where
- New Zealand
- Volunteers
- 807 people, healthy volunteers welcome
- Sponsor
- University of Auckland, New Zealand
Cigarette Smoking
Postnatal Smoking Relapse, Its Associated Risk Factors, and a Proactive Sustainable Preventive Intervention
This study will assess the extent of postpartum smoking relapse among Romanian women, the associated risk factors, and will develop, implement, and pilot-test a randomized trial smoking relapse intervention incorporating…
- Trial name
- PRISM (NCT02258568)
- Testing
- Smoking abstinence counseling
- Where
- Romania
- Volunteers
- 397 people, healthy volunteers welcome
- Sponsor
- Babes-Bolyai University
Nicotine Dependence, E-Cig Use
Research and Innovation to Stop E-cigarette/Vaping in Young Adults
The aim of this study is to test intervention components to help young adults quit vaping. A 2x2 factorial design will be used where all participants receive quitline-delivered behavioral phone counseling, and components to be…
- Trial name
- (RISE) (NCT04974580)
- Testing
- Nicotine patch, Phone Counseling, Digital Coaching
- Where
- United States
- Volunteers
- 508 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Adolescent Substance Use
Guiding Good Choices for Health
This study evaluates the feasibility and effectiveness of implementing Guiding Good Choices (GGC), an anticipatory guidance curriculum for parents of early adolescents, in three large, integrated healthcare systems.
- Trial name
- GGC4H (NCT04040153)
- Testing
- Guiding Good Choices
- Where
- 3 sites in United States
- Volunteers
- 3,636 people, healthy volunteers welcome
- Sponsor
- University of Washington
Sex, Cigarette Smoking
Mapping Brain Glutamate in Humans: Sex Differences in Cigarette Smokers
The proposed study evaluated sex differences in glutamate (Glu), with a focus on the dorsal anterior cingulate cortex (dACC), anterior insula, and thalamus, as well as how it is influenced by sex (males vs.
- Trial name
- NCT05279053
- Testing
- Abstinence and Smoking
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Vaping
A Virtual Reality Vaping Prevention Intervention for Adolescents
This study will examine E-Invite Only VR, a novel school-based universal e-cigarette prevention intervention that uses virtual reality (VR) to deliver prevention and emotion regulation skills-building content to middle school…
- Trial name
- NCT07362069
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Yale University
Cigarette Smoking, Nicotine Dependence
Reducing Tobacco Use Disparities Among Low-Income Adults
Most smokers, especially those who are poor, do not receive smoking cessation treatment during their healthcare visits. This study is evaluating a novel population health management intervention for low-income smokers.
- Trial name
- NCT03077737
- Testing
- Choose to Change, Enhanced usual care
- Where
- United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Tobacco Use Disorder
Combining a Smoke Ending Aid With Behavioral Treatment - 1
The purpose of this study is to combine a smoke ending aid with behavioral treatment.
- Trial name
- NCT00006151
- Testing
- Behavioral Therapy
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Peter Gariti