Clinical trials: Smoking
Tobacco Smoking
Computer Delivered and Community Health Worker Supported Smoking Cessation Intervention
The prevalence of tobacco smoking is high among persons with HIV (PWH). The investigators are piloting a two session computer-delivered intervention (CBI) with linkage to a community health worker (CHW) among hospitalized PWH…
- Trial name
- NCT04566159
- Testing
- CBI-CHW, Standard Care
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Johns Hopkins University
Smoking Cessation, Second Hand Tobacco Smoke
Smoke-free Home Intervention in Permanent Supportive Housing
The focus of this study is on expanding access to voluntary smoke-free homes to formerly homeless residents residing in permanent supportive housing and examining the impact of this intervention on reducing tobacco-caused…
- Trial name
- NCT04855357
- Testing
- Resident counselling, Staff Training
- Where
- United States
- Volunteers
- 452 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Tobacco Use Cessation
An Evidence Based Smoking Cessation Program for Persons Living With HIV/AIDS (Project Legacy)
The goal of this research study is to compare 2 different phone-based programs for quitting smoking for people with HIV/AIDS.
- Trial name
- NCT02029612
- Testing
- Nicotine Patch, Phone Counseling, Questionnaires
- Volunteers
- healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Smoking, Tobacco Use
BAT3221032: A Study to Evaluate the Effects of Switching From Cigarette Smoking to Using One of Five Variants of a Heated Tobacco Product on Biomarkers of Exposure and Biomarkers of Potential Harm in Healthy Subjects
This is a randomized, controlled, multi-center, open-label, 8-cohort parallel group study to assess changes in select biomarkers of exposure (BoE) and biomarkers of potential harm (BoPH) in generally healthy smokers switching to…
- Conditions
- Smoking, Tobacco Use, Tobacco Smoking
- Trial name
- NCT05142436
- Testing
- Product A: Non-Combusted Cigarette Variant 42001402 and product use Mode B, Product B: Non-Combusted Cigarette Variant 42001399 and product use Mode B, Product C: Non-Combusted Cigarette Variant 42001401 and product use Mode B
- Where
- 18 sites in United States
- Volunteers
- 806 people, healthy volunteers welcome
- Sponsor
- British American Tobacco (Investments) Limited
Lung Cancer
Metabolism of NNK Among African Americans
Metabolism and DNA adduct formation are critical in cancer induction by NNK. The investigators goal is to understand whether the observed ethnic/racial differences in lung cancer incidence are due to variations in NNK metabolism.
- Trial name
- Project 5 (NCT01158456)
- Where
- United States
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Masonic Cancer Center, University of Minnesota
Smoking
Computer-Assisted Intervention for Smoking During Pregnancy
This study will develop: 1. Develop the computer-based brief intervention and Contingency Management (CM) components, with repeated feedback from experts, prenatal clinic staff, and participants. 2.
- Trial name
- HPP (NCT01028131)
- Testing
- Computer-delivered brief intervention (5As), Contingency Management
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Wayne State University
Smoking Cessation
Mobile Smoking Treatment for Spanish-speaking Latinx Smokers
The specific aims of the project are to develop and test a Spanish language, mobile app for smoking cessation called Impacto.
- Trial name
- NCT04417075
- Testing
- Impacto (Mobile App), Dejar de Fumar Asistente (Mobile App)
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Houston
Tobacco Use Cessation
Feasibility of Delivering VergeRx at FQHCs
Cigarette smoking in the U.S. is highest among low income and Medicaid insured adults, and unfortunately, low-income smokers are even less likely to attempt to quit, less likely to use evidence-based treatments, and thus less…
- Trial name
- NCT06161675
- Testing
- QuitAid, SmokefreeTXT, Nicotine Replacement Therapy Patch
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Schizophrenia, Schizoaffective Disorder
A Study of Varenicline for Prevention of Relapse to Smoking in Patients With Schizophrenia or Bipolar Disorder
Varenicline (Chantix) is a smoking cessation treatment that was approved in 2006 by the FDA for treatment of nicotine dependence and may be particularly beneficial in smokers with schizophrenia or bipolar disorder.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Bipolar Disorder, Smoking
- Trial name
- SCRP (NCT00621777)
- Testing
- Varenicline
- Where
- 10 sites in United States
- Volunteers
- 247 people
- Sponsor
- Massachusetts General Hospital
Peri-Implant Health, Peri Implant Mucositis
Impact of Smoking on Immune Responses in Peri-implant Health and Disease
Peri-implant diseases are inflammatory conditions affecting the gums and bone around dental implants. Peri-implant mucositis causes inflammation in the gums, while peri-implantitis can also lead to bone loss and, in severe cases…
- Conditions
- Peri-Implant Health, Peri Implant Mucositis, Peri-implantitis
- Trial name
- NCT07750171
- Where
- Turkey (Türkiye)
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Gazi University
Nicotine Dependence Tobacco Product
Comparing SMS and E-mail Reminders in an Online Smoking Cessation Intervention
The primary purpose of the current study is to compare the effect of SMS-textmessage vs e-mail reminders on user engagement and proportion of reported quit attempts in an online smoking cessation intervention.
- Trial name
- NCT03276767
- Testing
- Endre
- Where
- 2 sites in Czechia, Norway
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Severe Mental Illness, Nicotine Dependence
Electronic Decision Support Systems for Smokers With Severe Mental Illness
This randomized clinical trial among SMI smokers assessed whether the EDSS with carbon monoxide monitor and health-checklist feedback lead to higher rates of initiation of smoking cessation treatment, days of smoking abstinence…
- Conditions
- Severe Mental Illness, Nicotine Dependence, Schizophrenia, Tobacco Use Disorder
- Trial name
- NCT01412866
- Testing
- EDSS with CO feedback and health checklist, EDSS with health checklist feedback alon
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Cancer, Smoking
Motivating a Spectrum of Cancer Patients to Quit Smoking
This study will assess feasibility and acceptability of an intervention designed to increase smoking cessation motivation among patients with a cancer not widely known to be smoking related.
- Trial name
- NCT04914000
- Testing
- Self-help Materials
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
PONV
Effect of Combination Dexmedetomidine Added to Fentanyl-based Intravenous Patient-controlled Analgesia on Nausea Vomiting in Highly Susceptible Patients Undergoing Lumbar Spinal Surgery: Prospective Double Blinded Randomized Controlled Trial
The aim of this study is to test the hypothesis that addition of dexmedetomidine to fentanyl-based intravenous patient controlled analgesia (PCA) reduces requirement of fentanyl bolus and consequent postoperative nausea and…
- Trial name
- NCT01840254
- Testing
- dexmedetomidine, normal saline
- Where
- South Korea
- Volunteers
- 108 people
- Sponsor
- Yonsei University
Cannabis Use, Cannabis Smoking
Longitudinal Study of Xenon-129 MRI Imaging Effects of Cannabis Smoking
This is a longitudinal study of the long-term health impact of cannabis smoking on the lungs. Participants will be followed over a period of 3 years, and impacts of cannabis smoking on the lungs will be measured with magnetic…
- Conditions
- Cannabis Use, Cannabis Smoking, Marijuana Smoking, Marijuana Usage
- Trial name
- NCT03909477
- Testing
- Hyperpolarized Xenon-129 MRI of the lungs, Computed Tomography (CT), Pulmonary Function Tests (PFTs)
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Bladder Cancer, Cervical Cancer
Bupropion in Helping Adults Stop Smoking
RATIONALE: Bupropion may help people stop smoking by decreasing the symptoms of nicotine withdrawal. Giving bupropion over a longer period of time may be effective in helping people stop smoking.
- Conditions
- Bladder Cancer, Cervical Cancer, Esophageal Cancer, Gastric Cancer
- Trial name
- NCT00534001
- Testing
- bupropion hydrochloride
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Roswell Park Cancer Institute
Nicotine Dependence, Nicotine Dependence, Cigarettes
Clinical Study Comparing 7 ENDS Products and 1 Combustible Cigarette Using 2 Delivery Methods.
A Randomized Study Comparing Nicotine Pharmacokinetics of Seven Electronic Cigarette Products and One Traditional Cigarette Across Two Delivery (10 puff and ad- libitum) Conditions, in Healthy Adult Smokers
- Conditions
- Nicotine Dependence, Nicotine Dependence, Cigarettes, Tobacco Use, Tobacco Smoking
- Trial name
- NCT03700112
- Testing
- JUUL Virginia Tobacco flavored 5.0% ENDS, PMI iQOS Heat sticks, Reynolds VUSE Solo ENDS - Original
- Where
- New Zealand
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Juul Labs, Inc.
Pregnancy, Smoking
Partner Involvement During Pregnancy and Its Association With Maternal Health Behaviors
This study assessed the relationship between pregnant women, partner support, and cigarette and alcohol use in pregnancy.
- Trial name
- NCT02428530
- Testing
- Questionnaires
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Saliva, Cortisol
Comparison of Saliva Biomarkers in Two Different Geographical Regions of Turkey
Periodontitis is a multifactorial, chronic inflammatory disease caused by many factors such as pathogenic microorganisms, host response, environmental and systemic factors.
- Conditions
- Saliva, Cortisol, Smoking, Tobacco, Periodontal Bone Loss
- Trial name
- NCT06809439
- Testing
- Non-Surgical Intervention, Saliva Collection (Baseline), Probing
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Smoking Cessation
Evaluation of Cessation Preferences of Menthol Smoker
The primary aim of this study is to determine menthol smokers' perception, product preference, and pattern of use across six products including, mint-flavored nicotine gum; non-flavored nicotine gum; mentholated nicotine inhaler…
- Trial name
- NCT02020005
- Testing
- Non-flavored 2mg nicotine gum, Non-flavored 4mg nicotine gum, Mint-flavored 2mg nicotine gum
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Minnesota