Clinical trials: Smoking, Tobacco
Tobacco Use Cessation
Comparative Effectiveness of Mobile Health Smoking Cessation Approaches Among Underserved Patients in Primary Care
This study will evaluate the comparative effectiveness of three smoking cessation therapies: mobile health (mHealth) application iCanQuit, mHealth application iCanQuit + Motiv8, and the Florida quit line.
- Trial name
- PROMOTE-UP (NCT05415761)
- Testing
- iCanQuit, iCanQuit+Motiv8, Florida quit line
- Where
- United States
- Volunteers
- 1,332 people, healthy volunteers welcome
- Sponsor
- University of Florida
Tobacco Use Cessation, Tobacco Smoking
Development of a Smoking Cessation Video Series
This study seeks to develop and test an internet video series aimed at helping individuals reduce cigarette smoking. Participants (daily smokers) will be asked to watch a series of six videos (approximately 6.5 minutes each)…
- Trial name
- NCT06443294
- Testing
- Smoking cessation video series.
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Wayne State University
Physician's Role, Smoking Cessation
Personalized Tobacco Treatment in Primary Care (MOTIVATE)
This study examines the application of precision treatment intervention for smoking cessation from both the clinician perspective and patient perspective, and compares it to usual care on tobacco treatment in the primary care…
- Conditions
- Physician's Role, Smoking Cessation, Smoking
- Trial name
- NCT05846841
- Testing
- Precision Treatment, Usual Care
- Where
- United States
- Volunteers
- 850 people
- Sponsor
- Washington University School of Medicine
Lung Cancer Screening, Tobacco Use Disorder
Multilevel Intervention for LDCT Lung Cancer Screening and Smoking Cessation Among African Americans
This study aims to reduce disparities and the burden of lung cancer among African American smokers by supporting a Multiple-level intervention integrating lung cancer screening and smoking cessation (MILS), followed the NIH DEIA…
- Conditions
- Lung Cancer Screening, Tobacco Use Disorder, Smoking Cessation
- Trial name
- NCT07576595
- Testing
- Smoking cessation multilevel Intervention
- Where
- 2 sites in United States
- Volunteers
- 250 people
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Peri-Implantitis, Peri-implant Mucositis
Association Between Smoking Habit and Peri-implant Diseases: a Case Control Study
Although smoking has been proposed as well, as a risk factor/indicator for peri-implantitis, there is currently no conclusive evidence. The current literature confronts the inconclusive evidence of tobacco for a risk factor.
- Conditions
- Peri-Implantitis, Peri-implant Mucositis, Bone Loss, Alveolar
- Trial name
- NCT04952428
- Testing
- Re-examination visit ("today visit")
- Where
- Spain
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Smoking, Cigarette
Tobacco Use Treatment in Cancer Patients
Tobacco use among cancer survivors reduces the effectiveness of cancer treatments, increases the risk for additional primary cancers, and increases mortality.
- Trial name
- NCT03482583
- Testing
- Nicotine Replacement Therapy, Referral to AHEC/Quitline
- Where
- 5 sites in United States
- Volunteers
- 90 people
- Sponsor
- University of Florida
Smoking
PET Imaging Study on Occupancy of Dopamine D2 Receptors and Genotypes After Bupropion Administration
Bupropion has different effects on D2 dopamine receptors according to genotype.
- Trial name
- NCT00846339
- Testing
- Bupropion
- Where
- South Korea
- Volunteers
- 12 people
- Sponsor
- Seoul National University Hospital
Orthopaedic Decision Making
Surgeon-Patient Communication: A Randomized Controlled Trial Evaluating the Impact of an Orthopaedic Related Smoking Cessation Discussion After Fracture Surgery
In this study, the investigators are interested in evaluating the impact of an orthopaedic related smoking cessation discussion after fracture surgery.
- Trial name
- NCT02440529
- Testing
- Intervention, Verbal Group
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Missouri, Kansas City
Nicotine Dependence Tobacco Product
Comparing SMS and E-mail Reminders in an Online Smoking Cessation Intervention
The primary purpose of the current study is to compare the effect of SMS-textmessage vs e-mail reminders on user engagement and proportion of reported quit attempts in an online smoking cessation intervention.
- Trial name
- NCT03276767
- Testing
- Endre
- Where
- 2 sites in Czechia, Norway
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Tobacco Use Disorder
Persistence-Targeted Smoking Cessation
The investigators propose to develop a theory-based smoking cessation intervention (called Persistence-targeted smoking cessation; PTSC).
- Trial name
- PTSC (NCT01654107)
- Testing
- Persistence Targeted Smoking Cessation, Clearing The Air, Nicotine lozenge
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Smoking Cessation
Technology and Telephone-Based Smoking Cessation
The goal of the proposed project is to design and assess the acceptability and usability of a mobile technology and telephone-facilitated treatment to improve treatment engagement in adult smokers with posttraumatic stress…
- Trial name
- RAP Smoking (NCT03492645)
- Testing
- Telephone-and technology-facilitated treatment protocol, Office-based treatment protocol
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Francisco
Smoking, Healthy Volenteers
Evaluation of GCF MMP-1, -8 and Growth Factor Levels in Smokers With Periodontal Health
Increased levels of cytokines in GCF have been demonstrated in smoker subjects with chronic periodontitis. It is not surprising that increased levels of inflammation associated molecules in GCF has been observed in smokers with…
- Trial name
- NCT02014857
- Testing
- Gingival Crevicular Fluid Sampling
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Ege University
Squamous Cell Carcinoma of Lung
Icotinib in Previously Treated Non/Light-smoking Patients With Advanced Squamous Cell Lung Cancer
This study is designed to evaluate the efficacy of icotinib at routine dose in previously treated non/light-smoking patients with advanced squamous cell lung cancer.
- Trial name
- NCT02009605
- Testing
- Icotinib
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Zhejiang University
Tobacco Use Disorder
Tobacco Use Intervention Among Radiation Oncology Patients
Tobacco prevention and intervention strategies in the general population are ongoing and evolving. However, strategies to help cancer patients overcome tobacco dependence have been limited.
- Trial name
- NCT00587353
- Testing
- Behavioral and pharmacologic tobacco use intervention
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Mayo Clinic
Tobacco Dependence
Comparisons of Nicotine-free Cigarettes, Extra Low Nicotine Cigarettes vs. Medicinal Nicotine
In this study, smokers will be randomly assigned to one of three conditions for six weeks: 1) nicotine-free cigarettes (0.05mg); 2) extra low nicotine cigarettes (0.3 mg); or 3) medicinal 4 mg nicotine lozenge.
- Trial name
- NCT00777569
- Testing
- Nicotine free cigarettes, Extra-low nicotine cigarettes, Nicotine Lozenge
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Pediatric Cancer
Cotinine Feedback as an Intervention to Change Parental/Caregiver Smoking Behavior Around Children With Cancer
RATIONALE: Providing parent/caregivers of children with cancer with education and evidence of secondhand smoke exposure can protect the child from future exposure to tobacco smoke.
- Trial name
- NCT01828502
- Testing
- Education, Cotinine Education
- Where
- 10 sites in United States
- Sponsor
- University of South Florida
Nicotine, Nicotine Vaping
Developing E-liquid Product Standards (Sweet Spot Study)
The Sweet Spot Study aims to evaluate the effect of e-liquids with nicotine varying in freebase (FB) levels and concentrations on the appeal of electronic cigarettes (ECs) in young adult EC users with minimal/no history of…
- Conditions
- Nicotine, Nicotine Vaping, E-cigarette Use
- Trial name
- NCT05864586
- Testing
- Vaping study EC A, Vaping study EC B, Vaping study EC C
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Inflammation, Smoking Cessation
Screening and Multiple Intervention on Lung Epidemics
This prospective randomized pilot trial will evaluate a multiple intervention program of prevention in lifelong smokers aiming at reduction of chronic inflammation status through treatment with low-dose acetylsalicylic acid…
- Conditions
- Inflammation, Smoking Cessation, Diet Modification, Physical Activity
- Trial name
- SMILE (NCT03654105)
- Testing
- Cytisine, Acetylsalicylic acid, Diet Modification and Physical Activity Increase
- Where
- Italy
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Vaping
Influencer Marketing and Adolescent E-cigarette Use
Adolescents (N = 700) participated in the online survey-based randomized experiment focused on understanding youth perceptions of e-cigarette influencer marketing on social media.
- Trial name
- NCT07420842
- Testing
- Youth Perceptions of Influencer Age and Fitness Contexts in E-Cigarette Marketing
- Where
- United States
- Volunteers
- 700 people
- Sponsor
- University of Southern California
Heavy Smoking
Bronchoscopy Screening for High-risk Population of Lung Cancer With Severe Smoking With Negative LDCT Screen
Based on the previous work of LDCT screening, in order to improve the screening rate of central lung cancer for LDCT negative and severe smokers, the investigators plan to conduct China's first large-scale fluorescent…
- Trial name
- NCT04413669
- Testing
- white light bronchoscopy & autofluorescence bronchoscopy
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Jiayuan Sun
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