Clinical trials: Smokers
Smoking Cessation
A Study Evaluating The Absorption Of Varenicline Into The Body From A Varenicline Patch Applied To The Skin
This study will evaluate the single-dose pharmacokinetics, safety, and tolerability of a varenicline patch applied to the skin.
- Trial name
- NCT01013454
- Testing
- varenicline free base patch
- Where
- Belgium
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pfizer
Smokers
CAT Score and Airway Limitation in Adult Smokers
This study aimed to show the relationship between CAT Score and airway limitation in smokers who applied to MSKU Chest Diseases Polyclinic with respiratory complaints (shortness of breath, cough, sputum, etc.) and underwent…
- Trial name
- CAT (NCT06644456)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Muğla Sıtkı Koçman University
Tobacco Smoking, Psychiatric Disorders
The Effect of Electronic Cigarette Use on Smoking Behaviors Among Smokers Receiving Outpatient Psychiatric Treatment
This study aims to establish the feasibility and acceptability of a project designed to investigate the impact of electronic cigarette use on combustible cigarette smoking and smoking-related factors among smokers with…
- Trial name
- NCT04014322
- Testing
- E-cigarette
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Fordham University
Tobacco Use Disorder
Smokers' Health Project: Self-Determination and Maintaining Tobacco Abstinence
These two studies will examine the role of autonomous motivation in maintained adherence. The first study will determine whether smokers are still abstinent from tobacco 32 months after starting in a previous project (Smoker's…
- Trial name
- SHP (NCT00178685)
- Testing
- Self-determination Intervention for Tobacco Dependence
- Where
- United States
- Volunteers
- 837 people
- Sponsor
- University of Rochester
Tobacco Toxicant Exposure
Determining Levels of [D10] Phenanthrene Tetraol in Smokers' Urine
The purpose of this research study is to better understand how people respond to cancer-causing chemicals in cigarette smoke. Some people are able to get rid of these chemicals as harmless agents while others suffer damage to…
- Trial name
- NCT01092650
- Testing
- Deuterated phenanthrene
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Smoking Cessation
A Phase I Study to Evaluate the Pharmacokinetics of Multiple Doses of Varenicline in Healthy Adolescent Smokers
This study will investigate the multiple dose pharmacokinetics, safety, and tolerability of two dose strengths of varenicline in adolescents aged 12 to 16 years who regularly smoke at least three cigarettes per day.
- Trial name
- NCT00463918
- Testing
- varenicline
- Where
- 16 sites in United States, United Kingdom
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Pfizer
Smoking, Anxiety Disorders
Smoking Termination / Anxiety Reduction Treatment (ST/ART)
The primary aim of this research study is to enhance smoking cessation outcome among smokers with anxiety disorders. The investigators are comparing two group treatment approaches: (1) An educational-supportive psychotherapy and…
- Trial name
- START (NCT01789125)
- Testing
- Nicotine Patch, Smoking Termination and Anxiety Reduction Treatment, Education-Supportive Psychotherapy
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- University of Houston
Lung Cancer, Smoking Cessation
PCORI-CER-1306-03385 Informed Decisions About Lung Cancer Screening
Educational research study where goal is to test educational materials that help people make informed decisions about lung cancer screening.
- Conditions
- Lung Cancer, Smoking Cessation, Tobacco Use Cessation
- Trial name
- NCT02286713
- Testing
- Patient Decision Aid, Standard Educational Information, Follow-Up Assessments: Questionnaires
- Where
- United States
- Volunteers
- 516 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Tobacco Use, Tobacco Use Cessation
Integrating CHWs Into Prenatal Care for Maternal Smoking Cessation
This develops a novel behavioral tobacco cessation program for pregnant smokers in San Bernardino County.
- Conditions
- Tobacco Use, Tobacco Use Cessation, Tobacco Use in Childbirth
- Trial name
- SFHOPE (NCT06438549)
- Testing
- HCP-CHW Integration into Prenatal Care for Smoking Cessation, Control Arm
- Where
- 2 sites in United States
- Volunteers
- 105 people
- Sponsor
- Loma Linda University
Cigarette Smoking Behavior, E-Cigarette Use
Project E-Shift: A Harm Reduction Intervention for Chronically Unhoused Smokers.
This pilot randomized trial tested whether switching to e-cigarettes, compared with standard nicotine replacement therapy (NRT; patch and gum), helped adults with a history of chronic homelessness stop smoking combustible…
- Trial name
- ESHIFT (NCT07897058)
- Testing
- E-cigarette, Nicotine replacement therapy (patch, gum), both arms, CO-contingent financial incentives, both arms
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Thomas Jefferson University
Smoking Cessation
Nonsmokers Helping Smokers Quit
This study examines whether nonsmokers can be mobilized to help smokers quit. We will test, via mail campaign, whether targeting nonsmokers can be equally effective in increasing smokers' quit rate as targeting smokers directly.
- Trial name
- Project BEST (NCT02010697)
- Testing
- Messages targeting nonsmokers, Messages targeting smokers
- Where
- United States
- Volunteers
- 3,125 people
- Sponsor
- University of California, San Diego
Smokers
Nicotine Patch Safety Study
The purpose of this study is to evaluate the safety profile of a repeated application of a new transdermal patch compared to a reference product during 3 weeks, in a large population.
- Trial name
- NCT01655082
- Testing
- V0116 transdermal patch, Nicotine transdermal patch
- Where
- 4 sites in France
- Volunteers
- 160 people
- Sponsor
- Pierre Fabre Medicament
Lung Cancer
CT Scans in Screening for Lung Cancer in Current and Former Smokers
RATIONALE: Screening tests, such as CT scanning, may help doctors find cancer cells early and plan better treatment for lung cancer.
- Trial name
- NCT00625690
- Testing
- questionnaire administration, computed tomography, evaluation of cancer risk factors
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Nebraska
Cigarette Smoking, Home Access to Internet and Email
Web-based Smoking Cessation Intervention: Transition From Inpatient to Outpatient
This project, "Web-based Smoking Cessation Intervention: transition from inpatient to outpatient," addresses smoking among hospitalized patients, whose rates are higher than among the general population.
- Conditions
- Cigarette Smoking, Home Access to Internet and Email, Cognitively and Physically Able to Participate, English Speaking and Reading
- Trial name
- NCT01277250
- Testing
- Web-based smoking cessation program
- Where
- United States
- Volunteers
- 1,548 people
- Sponsor
- University of Alabama at Birmingham
Smoking
CSD170302: Study to Assess Nicotine Uptake in Smokers From Electronic Cigarettes
To determine the rate and amount of nicotine uptake with 10-minute ad libitum use of four different marketed electronic cigarettes.
- Trial name
- NCT03233997
- Testing
- FT21018, FT21033, FT21034
- Where
- United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- RAI Services Company
Electronic Cigarette Use
Effects of Electronic Cigarette Flavors on Abuse Liability in Smokers (P3-Taste)
The purpose of this study is to determine if abuse liability indices will be impacted by varying flavors and e-cigarette (ECIG) nicotine delivery capability (i.e., nicotine flux) among current combustible cigarette users.
- Trial name
- NCT05971823
- Testing
- Tobacco product administration and assessment
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Tobacco Use Cessation
Mobile Media-Rich Interactive Guideline System (MMRIGS) Pilot Study
The goal of this research study is to learn about 2 different interactive methods that are designed to help people with HIV/AIDS stop smoking.
- Trial name
- NCT02302859
- Testing
- Nicotine Patch, Questionnaires, Pamphlet
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Cigarette Smoker, Current Every Day Smoker
Enhanced Smoking Cessation for University Students
This trial studies how well a new smoking cessation and prevention intervention works in enhancing smoking cessation for university students. The new intervention may be easier to use for students to quit smoke.
- Trial name
- NCT00941395
- Testing
- Survey Administration
- Where
- 2 sites in United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Smoking, Asthma
E-cigarettes for Harm Reduction in Adults With Asthma
Smoking is the main cause of preventable disease and death in the US and impacts respiratory illnesses including COPD and asthma.
- Conditions
- Smoking, Asthma, Electronic Cigarette Use, Cigarette Smoking
- Trial name
- SWAP (NCT05278065)
- Testing
- Nicotine
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Brown University
Recurrent Non-small Cell Lung Cancer, Stage IIIB Non-small Cell Lung Cancer
Carboplatin, Paclitaxel, and Bevacizumab With or Without Erlotinib Hydrochloride in Treating Non-Smokers With Advanced Non-Small Cell Lung Cancer
This randomized phase II trial studies how well carboplatin, paclitaxel, and bevacizumab work with or without erlotinib hydrochloride in treating non-smokers with advanced non-small cell lung cancer.
- Conditions
- Recurrent Non-small Cell Lung Cancer, Stage IIIB Non-small Cell Lung Cancer, Stage IV Non-small Cell Lung Cancer
- Trial name
- NCT00976677
- Testing
- erlotinib hydrochloride, paclitaxel, carboplatin
- Where
- 108 sites in United States
- Volunteers
- 10 people
- Sponsor
- National Cancer Institute (NCI)