Clinical trials: Smokers
Healthy Non-smoker
Matrix on Fruit Constituent Bioavailability
Primary objective is to evaluate the influence of matrix on the bioavailability of key phytochemical constituents in fruits and their subsequent effect on chronic disease risk factors.
- Trial name
- FRT (NCT01908634)
- Testing
- Milk-based Strawberry Beverage without meal, Water-Based Strawberry Beverage without meal, Milk-based strawberry Beverage with meal
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology
Cigarette Smoking, Current Smoker
Quit4Health Intervention in Supporting Smoking Cessation and Preventing Smoking Initiation in Young Adults
This trial studies how well Quit4Health intervention works in supporting smoking cessation and preventing smoking initiation in young adults.
- Trial name
- NCT04009590
- Testing
- Educational Intervention, Questionnaire Administration, Smoking Cessation Intervention
- Where
- United States
- Volunteers
- 579 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Chronic Obstructive Pulmonary Disease, Smoker Lung
Lung Elastrosonography in Diagnosis and Stratification of COPD and Fibrosis
Elastosonography is an advanced ultrasound technique, nowadays available in many portable systems, allowing to measure elasticity and stiffness of parenchymatous organs.
- Trial name
- ELAS-P-1 (NCT04149652)
- Testing
- Lung Elastosonography
- Where
- Italy
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero-Universitaria di Parma
Smokers
Oral Mucosal Lesions Among Smokers in an Egyptian Population.
This cross-sectional study will assess the prevalence of oral changes among smokers in an Egyptian cohort (patients attending to the hospital of Faculty of Dentistry - Cairo University), aiming that this study can serve as a…
- Trial name
- NCT03299595
- Testing
- printed questionnaire
- Where
- Egypt
- Volunteers
- 824 people, healthy volunteers welcome
- Sponsor
- Cairo University
Smokers, Never Smokers
Prefatory Study to Explore Changes in Nasal Mucociliary Clearance and to Standardize Nasal Scraping Procedure
This study intends to evaluate the nasal mucociliary clearance (NMC) by determining the value obtained for saccharin transit time (STT) test over the course of 12 hours following a single cigarette use in adult smokers, to…
- Trial name
- NCT03086707
- Testing
- Cigarette
- Where
- 2 sites in United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Hospitalized Smokers, CBT
Smoking Cessation in Hospitalized Patients Using an App
This study generates a new proposal for intensive intervention following the recommendations to quit smoking in hospitalized patients, providing intensive, accessible and individualized treatment, as well as long-term follow-up…
- Conditions
- Hospitalized Smokers, CBT, Smoking Cessation, Mhealth
- Trial name
- NoFumo+ (NCT04502004)
- Testing
- App for health=mhealth
- Where
- Spain
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- University of the Balearic Islands
Current Smoker, Former Smoker
Acetylsalicylic Acid Compared to Placebo in Treating High-Risk Patients With Subsolid Lung Nodules
This randomized phase II trial studies acetylsalicylic acid compared to placebo in treating high-risk patients with subsolid lung nodules. A nodule is a growth or lump that may be malignant (cancer) or benign (not cancer).
- Conditions
- Current Smoker, Former Smoker, Multiple Pulmonary Nodules, Tobacco Use Disorder
- Trial name
- NCT02169271
- Testing
- Aspirin, Laboratory Biomarker Analysis
- Where
- 2 sites in United States, Italy
- Volunteers
- 109 people
- Sponsor
- National Cancer Institute (NCI)
Cigarette Smoker, Current Every Day Smoker
Tailored Smoking Cessation Intervention in Promoting Sexual and Gender Minority Smokers to Quit Smoking
This trial studies how well tailored smoking cessation intervention works in promoting sexual and gender minority smokers to quit smoking.
- Trial name
- NCT03669120
- Testing
- Informational Intervention, Telephone-Based Intervention
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Cigarette Smoker, Current Every Day Smoker
APPSPIRE App in Preventing Students From Smoking
This trial studies how well APPSPIRE, a smartphone app, works in preventing students from smoking. Technology-driven intervention programs, such as the APPSPIRE app, have the potential to increase access to health behavior…
- Conditions
- Cigarette Smoker, Current Every Day Smoker, Student
- Trial name
- NCT01967082
- Testing
- APPSPIRE, Focus Group, Survey Administration
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- M.D. Anderson Cancer Center
Healthy Lifetime Non-smokers
Evaluation of Acute and Subacute Effects of Nicotine Free Electronic Cigarette(NCFE) Vapors
This aim will examine the acute and subacute exposures to electronic cigarette (EC) vapor generated from e-liquids without nicotine (NFEC) on life-time non smokers subjects by measuring changes in nasal ion transport and TGF-β…
- Trial name
- NCT02585791
- Testing
- Propylene Glycol, vegetable glycerin, PG+VG
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Miami
Smoker, Schizophrenia Diagnosis
Tobacco Craving and Triggers in Persons With Schizophrenia
Investigators have recently completed a pilot study exploring the safety and efficacy of using a virtual-reality based cue platform to elicit craving in smokers with schizophrenia(SWS)(Wehring et al, unpublished).
- Trial name
- NCT01846065
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Maryland, Baltimore
Heathy Volunteers, Smokers
Repair, Remodeling and Regeneration of the Bronchial Epithelium of COPD Patients
COPD is characterized by exagerated decline FEV1 related to obstructive non reversible airflow. This could be the consequence of structural changes and inflammatory pattern of the bronchial wall.
- Conditions
- Heathy Volunteers, Smokers, COPD
- Trial name
- RRR (NCT02354677)
- Testing
- In vitro experiments on bronchial epithelial cells
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Healthy Subjects, Smokers
Multiple Breath Washout (MBW) Using Sulfur Hexafluoride Reference Values and Influence of Anthropometric Parameters
Multiple breath washout (MBW) using Sulphur hexafluoride (SF6) has the potential to reveal ventilation heterogeneity in obstructive lung disease which is frequent in patients with small airway disease.
- Conditions
- Healthy Subjects, Smokers, Non-smokers
- Trial name
- NCT04099225
- Testing
- Multiple breath washout (MBW) testing
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Universitätsmedizin Mannheim
Chronic Obstructive Pulmonary Disease (COPD), Age Matched Healthy Volunteers (Non-smokers)
Effect of Symbicort on HAT and HDAC in Sputum Macrophages of COPD
The purpose of the study is to compare histone acetyltransferase (HAT) and histone deacetylase (HDAC) expressions and activities in induced sputum macrophages obtained from patients with moderate to severe COPD and age-matched…
- Trial name
- NCT00291408
- Testing
- Skin Prick Test, Impulse Oscillometry, Exhaled Nitric Oxide
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Imperial College London
Healthy Smokers, Healthy Non-smokers
Biomarkers of iNOS Activity in COPD, Asthma, Healthy Control
This pilot study will measure the baseline levels and the intra- and inter-subject variability of exhaled (alveolar and bronchial) and nasal NO in smoking subjects with mild and moderate COPD on or off steroid treatment, smoking…
- Conditions
- Healthy Smokers, Healthy Non-smokers, Patients With Mild Asthma, Patints With COPD (GOLD II)
- Trial name
- NCT00159302
- Testing
- Induced Sputum, Exhaled Nitric Oxide, Nasal Nitric Oxide
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Imperial College London
Healthy Non-smokers, Current Smokers
Markers for Chronic Obstructive Pulmonary Disease (COPD)
The primary aim of this study is to exploit a difference between COPD patients, chronic smokers without COPD and healthy non-smoking subjects.
- Conditions
- Healthy Non-smokers, Current Smokers, COPD Patients
- Trial name
- NCT00180622
- Testing
- Spirometry, Exhaled Nitric Oxide and Carbon Monoxide, Exhaled Breath Condensate
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Imperial College London
Nicotine Dependent Cigarette Smoker
The Get Quit - Stay Quit Study
Narrative: Tobacco smoking remains the single biggest cause of premature death in the United States and the leading cause of cancer and death from cancer.
- Trial name
- GQSQ (NCT01980485)
- Testing
- Lung Age feedback and exhaled carbon monoxide, No Lung Age Feedback
- Where
- 4 sites in United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Non-smoker, ADHD
Nicotine, Non-Smokers With and Without ADHD, and Genetics Study
The overall goal of the proposed research is to evaluate the behavioral and genetic mechanisms of smoking risk in non-smoking young adults (aged 18-25 years of age) with and without ADHD using a novel laboratory-based model of…
- Trial name
- NNSG (NCT01819259)
- Testing
- Nicotine nasal spray
- Where
- United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Scott Kollins, PhD
Cigarette Smoker, Current Every Day Smoker
Enhanced Smoking Cessation for University Students
This trial studies how well a new smoking cessation and prevention intervention works in enhancing smoking cessation for university students. The new intervention may be easier to use for students to quit smoke.
- Trial name
- NCT00941395
- Testing
- Survey Administration
- Where
- 2 sites in United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Healthy Smokers
Effect Of Deep Breathing Exercises In Smokers
To determine the effect of deep breathing exercises on lung function in healthy smokers.
- Trial name
- NCT03728530
- Testing
- Deep Breathing exercises
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Isra University