Clinical trials: Smokers
Tobacco Dependence, Schizophrenia
Cigarette Smoking in Smokers With and Without Schizophrenia
Higher rates and severity of tobacco dependence in people with schizophrenia, as compared with the general population, contribute to the lower life expectancy seen in this population.
- Trial name
- NCT04001114
- Testing
- Sampling Research Cigarettes
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
ADHD, Smoking
Smoking Cessation for Adults With Attention Deficit Hyperactivity Disorder (ADHD)
The objective of this study is to evaluate whether Osmotic-Release Methylphenidate (OROS MPH), relative to placebo, increases the effectiveness of standard smoking treatment (i.e., nicotine patch and individual smoking cessation…
- Trial name
- NCT00253747
- Testing
- Osmotic-Release Methylphenidate
- Where
- 6 sites in United States
- Volunteers
- 255 people
- Sponsor
- University of Cincinnati
Tobacco Dependence
Reduced Nicotine Cigarettes in Smokers With Mood and Anxiety Disorders
The overall aim of this project is to evaluate the effect of progressive nicotine reduction in cigarettes on smoking behavior, toxin exposure and psychiatric symptoms in smokers with comorbid mood and/or anxiety disorders.
- Trial name
- NCT01928758
- Testing
- Reduced Nicotine Content Cigarettes, Usual Nicotine Content Cigarettes
- Where
- 2 sites in United States
- Volunteers
- 245 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Periodontitis, Periodontal Diseases
Effect of Three Periodontal Therapies in Current Smokers and Non-Smokers
The purpose of this study is to determine in current and non-smokers the clinical and microbiological effects of 3 therapies: scaling and root planing (SRP) alone; SRP in combination with the orally administered antibiotic…
- Trial name
- NCT00066066
- Testing
- Scaling and root planing, Metronidazole, Amoxicillin
- Where
- United States
- Volunteers
- 146 people
- Sponsor
- The Forsyth Institute
Smoking Cessation
Use of Nicotine Replacement Therapy (NRT) Sample and Brief Smoking Cessation Advice for Recruiting Smokers
Background More than 60% of the daily smokers in Hong Kong have never tried and have no intention to quit smoking. About 30.8% of daily smokers attempted to quit but failed.
- Trial name
- NCT03717051
- Testing
- Nicotine replacement therapy (NRT) sampling, Medication counseling
- Where
- Hong Kong
- Volunteers
- 834 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Vaping, Nicotine Dependence
Varenicline For Nicotine Vaping Cessation In Non Smoker Vaper Adolescents
The Investigators propose a randomized, placebo-controlled trial to test the hypothesis that varenicline added to group behavioral and texting support will be well tolerated and improve vaping cessation rates among nicotine…
- Trial name
- Pilot (NCT04602494)
- Testing
- Varenicline
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Massachusetts General Hospital
Smoking Cessation, Harm Reduction
Assisting Smokers to Switch to a JUUL E-Cigarette by Devaluing Combustible Cigarettes
This study will evaluate a reward devaluation strategy in which smokers use the JUUL e-cigarette immediately before any combustible cigarettes (CCs) are smoked.
- Conditions
- Smoking Cessation, Harm Reduction, E-Cig Use, Cigarette Smoking
- Trial name
- RECON (NCT04188197)
- Testing
- JUUL
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rose Research Center, LLC
Nicotine Addiction, E-Cig Use
Sex Differences in E-cig Perception: Study 1
The primary objective is to examine the influence of sex on sensory effects, appeal, and reinforcing value of nicotine containing e-cigs in popular flavor components; sweet and cooling.
- Conditions
- Nicotine Addiction, E-Cig Use, Cigarette Smoking, Sex Differences
- Trial name
- NCT05432830
- Testing
- E-liquid Flavor 1, E-liquid Flavor 2, E-liquid Flavor 3
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Yale University
Nicotine Dependence, Opiate Dependence
Developing a Smoking Cessation Intervention for Methadone Maintained Smokers
The purpose of this study is to pilot and evaluate, in a randomized controlled trial, the immediate and long-term effects of a newly developed, tailored, intensive smoking cessation intervention among methadone maintained smokers…
- Trial name
- NCT01393392
- Testing
- Intensive, tailored intervention, NJ Quitline Referral
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Rutgers, The State University of New Jersey
Smoking Cessation
A Study of Cytisinicline for Smoking Cessation in Adult Smokers
This placebo-controlled Phase 3 study is being conducted at sites within the United States to evaluate 3 mg cytisinicline 3 times daily (TID) for treatment duration of 42 days/6 weeks and evaluate 3 mg cytisinicline TID for…
- Trial name
- ORCA-2 (NCT04576949)
- Testing
- Cytisinicline, Behavioral support
- Where
- 17 sites in United States
- Volunteers
- 810 people
- Sponsor
- Achieve Life Sciences
Smoking Cessation
A Text Messaging Program for Smokers in Primary Care
This study is a four arm pilot randomized controlled trial testing the effect of a 12 week text messaging intervention and a mailed nicotine medication intervention, alone and in combination to a control condition consisting of…
- Trial name
- GR2Q (NCT03174158)
- Testing
- Mailed nicotine replacement therapy, Text messaging, Brief advice
- Where
- United States
- Volunteers
- 153 people
- Sponsor
- Massachusetts General Hospital
Smoking
Airway and Pulmonary Vascular Endothelial Function in Healthy Smokers: Effect of Inhaled Glucocorticosteroid Treatment
The purposes of the present proposal are to 1) compare inhaled albuterol-induced changes in airway blood flow (Qaw), and in CO and Ppas in healthy current smokers and lifetime non-smokers as an index of endothelial function in…
- Trial name
- smoker3 (NCT02141633)
- Testing
- echocardiogram plus albuterol, airway blood flow plus albuterol, Fluticasone propionate
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Miami
Tobacco Use Disorder, Smoking Cessation
Development of a mHealth Intervention for Ambivalent Smokers
The current pilot study will assess the feasibility and acceptability of a novel mHealth app designed for people who are ambivalent about quitting smoking.
- Conditions
- Tobacco Use Disorder, Smoking Cessation, Motivation, Behavior, Smoking
- Trial name
- NCT04560868
- Testing
- Control mHealth program, Experimental mHealth program, Nicotine patch
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente