Clinical trials: Small Intestinal Bacterial Overgrowth
SIBO, Small Bowel Bacterial Overgrowth Syndrome
Clinical Utility of Handheld Hydrogen Breathalyzer in Identification of Food Sensitivities (AIRE Study)
Small intestinal bacterial overgrowth (SIBO) is defined as a condition in which an abnormally high amount of coliform bacteria is present in the small bowel and results in premature anaerobic fermentation of carbohydrates before…
- Trial name
- AIRE (NCT04309396)
- Testing
- Hydrogen content recording
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Johns Hopkins University
Chronic Abdominal Pain, Small Intestinal Bacterial Overgrowth
Is Chronic Abdominal Pain in Pediatric Patients Due to Small Intestinal Bacterial Overgrowth?
Chronic abdominal pain (CAP) is an extremely pervasive childhood condition and, like IBS in adults, it is one of the functional bowel disorders without a clear framework of understanding or an effective treatment.
- Trial name
- CAP&SIBO (NCT00619970)
- Testing
- Lactulose Breath Test, xifaxan
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
Irritable Bowel Syndrome
A Longitudinal Study to Identify IBS Phenotypes Using Fecal Microbiota and Hydrogen Breath Testing
Diarrhea-predominant irritable bowel syndrome (IBS-D) is a highly prevalent but poorly understood condition with limited treatment options.
- Trial name
- NCT03219528
- Testing
- Rifaximin 550 MG, Low FODMAP Diet
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- University of Michigan
Small Bowel Bacterial Overgrowth, Gastrointestinal Diseases
Transit Time and Bacterial Overgrowth Using SmartPill Capsule
The primary purpose of this exploratory study is to measure orocecal transit time using the SmartPill ambulant capsule technology and to compare this with the lactulose hydrogen breath test.
- Conditions
- Small Bowel Bacterial Overgrowth, Gastrointestinal Diseases, Stomach Diseases, Digestive System Diseases
- Trial name
- NCT00577772
- Testing
- Xifaxan, SmartPill, Lactulose hydrogen breath test (H_2BT)
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Gastrointestinal Motility Disorder, Intestinal Disease
Lanreotide in the Treatment of Small Bowel Motility Disorders
This is a human research study looking at the effectiveness of Lanreotide (study medication) in treating small bowel motility disorders.
- Trial name
- NCT03012594
- Testing
- Lanreotide
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Northwell Health
Parkinson's Disease
Weight Loss in Parkinson's Disease and Role of Small Bowel Bacterial Overgrowth
The potential role of small bowel bacterial overgrowth (SBBO) in weight loss occurring in patients with Parkinson's Disease (PD) has not previously been examined.
- Trial name
- NCT01662791
- Testing
- Rifaximin
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Mayo Clinic
Chronic Idiopathic Constipation
Lubiprostone Effect on Gastrointestinal Tract Transit Times Measured by Smartpill in Patients With Chronic Constipation
The purpose of this study is to determine if lubiprostone may change the rate of movement of food and activities in the stomach and intestines in subjects whose gastrointestinal (GI) tract is slower due to constipation.
- Trial name
- NCT01469819
- Testing
- Lubiprostone
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
Celiac Disease
Rifaximin for the Treatment of Persistent Symptoms in Patients With Celiac Disease
Celiac disease is a condition in which the small intestine is damaged by gluten, the storage protein of wheat and similar proteins in barley and rye.
- Trial name
- NCT01137955
- Testing
- Rifaximin
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Columbia University
Parkinson's Disease, Small Intestinal Bacterial Overgrowth
Treating Bacterial Overgrowth in Parkinson's Disease
This study investigates the effect of treating Small Intestinal Bacterial Overgrowth (SIBO) in patients with Parkinson's Disease (PD).
- Trial name
- SIBO-PD (NCT02470780)
- Testing
- Rifaximin
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Cincinnati
Irritable Bowel Syndrome, Small Intestinal Bacterial Overgrowth
Gulf War Digestive Health Study
The purposes of this study are to estimate the burden of disease due to chronic gastrointestinal illness in PG veterans, to evaluate whether Small Bowel Bacterial Overgrowth (SBBO) is associated with chronic diarrhea in PG…
- Trial name
- NCT00680836
- Testing
- Rifaximin
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- US Department of Veterans Affairs
Constipation
Effects of Lubiprostone on Small Bowel and Colonic Bacteria: A Correlation Study With Segmental and Whole Gut Transit
Patients with constipation often have bloating and abdominal distension. It is unclear if this is related to intestinal bacteria.
- Trial name
- NCT00844831
- Testing
- Lubiprostone
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Louisville