Clinical trials: Sleeve
Sleeve Gastrectomy, Obesity & Overweight
8-Year Outcomes After Sleeve Gastrectomy
Obesity is a major global public health concern, and bariatric surgery is recognized as the most effective treatment for achieving sustained weight loss and improving obesity-related comorbidities.
- Trial name
- NCT07348822
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Medipol University
Ultrasound, External Oblique Intercostal Plane Block
Ultrasound-Guided External Oblique Intercostal Plane Block Versus Subcostal Transversus Abdominis Plane Block For Perioperative Analgesia in Laparoscopic Sleeve Gastrectomy
This study aims to compare the analgesic efficacy, duration of analgesia, and overall opioid consumption between the external oblique intercostal plane (EOIP) block and subcostal transversus abdominis plane (TAP) block in…
- Conditions
- Ultrasound, External Oblique Intercostal Plane Block, Subcostal Transversus Abdominis Plane Block, Perioperative Analgesia
- Trial name
- NCT07366138
- Testing
- External oblique intercostal plane block, Subcostal transversus abdominis plane block
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Benha University
Bariatric Surgery, Roux-en Y Gastric Bypass
Gastro-Intestinal Digestion and Physiology After Bariatric Surgery
The goal of this clinical trial is to characterize gastrointestinal digestion and physiology in patients after bariatric surgery, or people living with obesity.
- Conditions
- Bariatric Surgery, Roux-en Y Gastric Bypass, Sleeve Gastrectomy, Obesity & Overweight
- Trial name
- GIBa (NCT07286968)
- Testing
- Gastro-intestinal aspiration, Telemetric
- Where
- Netherlands
- Volunteers
- 51 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Bariatric Surgery (Sleeve Gastrectomy ), Hemodynamics
Effect of Intraoperative Position Change on Hemodynamics and Electrocardiography
The combined effects of obesity-related cardiac structure and function changes, comorbidities, pneumoperitoneum technique, and reverse Trendelenburg position may complicate anesthesia management by affecting intraoperative…
- Conditions
- Bariatric Surgery (Sleeve Gastrectomy ), Hemodynamics, Electrocardiography
- Trial name
- NCT06835166
- Testing
- 12-lead electrocardiography measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Firat University
Metabolic Dysfunction-Associated Steatotic Liver Disease, Metabolic Dysfunction-Associated Steatohepatitis
Study of the Link Between MASH ( Metabolic Dysfunction-Associated Steatohepatitis) and MAMs (Mitochondria-Associated Membranes ) Alteration in Patients Undergoing Bariatric Surgery - MAMBA
The main research hypothesis is that alterations in the communication between the endoplasmic reticulum (ER) and the mitochondria at contact sites called mitochondria-associated membranes (MAMs) occurs in different hepatic cell…
- Conditions
- Metabolic Dysfunction-Associated Steatotic Liver Disease, Metabolic Dysfunction-Associated Steatohepatitis, Sleeve Gastrectomy, Gastric Bypass Surgery
- Trial name
- MAMBA (NCT06868992)
- Testing
- Bariatric surgery (Sleeve Gastrectomy or Gastric Bypass)
- Where
- 2 sites in France
- Volunteers
- 20 people
- Sponsor
- Hospices Civils de Lyon
Sleeve Gastrectomy
Powered Handle Primary Sleeve Gastrectomy Study
The objective of this prospective, single arm, single-center study is to evaluate patients who are undergoing primary sleeve gastrectomy procedures and are surgically treated with the AEON Endoscopic Powered Handle Stapler and…
- Trial name
- NCT06474637
- Testing
- AEON Endoscopic Powered Stapler Handle and Reload
- Where
- Lithuania
- Volunteers
- 100 people
- Sponsor
- Lexington Medical Inc.
Obesity & Overweight, Sleeve Gastrectomy
Istmin Levels in Laparoscopik Sleeve Gastrectomy
Obesity is a multifactorial disease which has become a public health problem with increasing frequency, especially in recent years.
- Conditions
- Obesity & Overweight, Sleeve Gastrectomy, Adipokines
- Trial name
- NCT07335549
- Testing
- Preoperative Serum Isthmin Levels, Postoperative Third Month's Serum Isthmin Levels, Preoperative BMI
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Laparoscopic Sleeve Gastrectomy (LSG), Thoracic Lung Resection Procedure
A Study of ECHELON 3000 (Next Generation Powered Stapler) in General Abdominal and Thoracic Lung Resection Procedures
The purpose of this study is to assess the safety and performance of the ECHELON 3000 Stapler (next generation powered stapler) and reload system in participants undergoing laparoscopic sleeve gastrectomy or lung resection…
- Trial name
- NCT05519215
- Testing
- ECHELON 3000 Stapler
- Where
- 8 sites in United States
- Volunteers
- 244 people
- Sponsor
- Ethicon Endo-Surgery
Obesity (Disorder), Morbid Obesity
Chrono-ALIGN: A Chronotype-Based Chrono-Nutrition Intervention in Post-Bariatric Patients
This randomized controlled trial will evaluate the impact of chrono-nutrition, a dietary approach that aligns meal timing with the body's circadian rhythms, on weight change, metabolic outcomes, appetite, and gut microbiota in…
- Conditions
- Obesity (Disorder), Morbid Obesity, Bariatric Sleeve Gastrectomy, Meal Time
- Trial name
- Chrono-ALIGN (NCT07324044)
- Testing
- Standard Post-Bariatric Care (Control), Early Time-Restricted Eating (eTRE), Chronotype-Based Chrono-Nutrition (CB-CN)
- Where
- Saudi Arabia
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- King Saud University
Laparoscopic Sleeve Gastrectomy (LSG), Erector Spinae Plane Block
Comparing Perioperative Analgesia After Ultrasound Guided Bilateral Erector Spinae Plane Block and Thoracic Paravertebral Block in Laparoscopic Sleeve Gastrectomy Patients
The aim of this study is to compare the efficacy of ultrasound-guided bilateral erector spinae plane block and thoracic paravertebral block on perioperative analgesic control for 24 hours postoperative and fast recovery of…
- Conditions
- Laparoscopic Sleeve Gastrectomy (LSG), Erector Spinae Plane Block, Thoracic Paravertebral Block
- Trial name
- NCT06798103
- Testing
- Erector Spinae Plane Block, Thoracic paravertebral block
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Pain, Postoperative, Obesity, Morbid
Effect of Bilateral Rectointercostal Fascial Plane Block on Postoperative Pain After Laparoscopic Sleeve Gastrectomy
This randomized controlled study aims to evaluate the effectiveness of the bilateral rectointercostal fascial plane (RIB) block for postoperative pain management in patients undergoing laparoscopic sleeve gastrectomy.
- Conditions
- Pain, Postoperative, Obesity, Morbid, Laparoscopic Sleeve Gastrectomy (LSG), Opioid Use
- Trial name
- NCT07253610
- Testing
- Bilateral Rectointercostal Fascial Plane Block, Intravenous Patient-Controlled Analgesia (IV PCA) with Morphine
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Samsun University
Obesity, Bariatric Surgery
Modified Thoracoabdominal Nerve Plane Block In Laparoscopic Sleeve Gastrectomy
Ultrasound-guided Modified Thoracoabdominal Nerve Plane Block (M-TAPA) is performed into the costochondral aspect at the 9th-10th costal level by injecting local anesthetics deep into the chondrium.
- Conditions
- Obesity, Bariatric Surgery, Laparoscopic Sleeve Gastrectomy, Acute Post Operative Pain
- Trial name
- NCT06515691
- Testing
- M-TAPA block, Postoperative pain management
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul Medipol University Hospital
Postoperative Nausea and Vomiting, Postoperative Pain After Laparoscopic Sleeve Gastrectomy
Paragastric Block for Pain and PONV in Sleeve Gastrectomy
This single-center, prospective, randomized, double-blind controlled trial aims to evaluate the effects of intraoperative paragastric block (PGBLOCK) on early postoperative visceral pain, postoperative nausea and vomiting (PONV)…
- Trial name
- BLOCK-SG (NCT07274215)
- Testing
- Bupivacaine 0.5%, Isotonic Saline (0.9% NaCl)
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Umraniye Education and Research Hospital
Severe Obesity, Sleeve Gastrectomy
Longitudinal Retrospective Analysis of Prospectively Collected Data for Outcomes After Primary Sleeve Gastrectomy (N=20 000) in the Swedish National Quality Registry SOReg (Scandinavian Obesity Surgery Registry)
The main questions to answer are: Weight outcomes in weight strata over time? What was the proportion of patients reaching sufficient weight outcome in different weight strata? To what extent are co-morbid conditions improved or…
- Trial name
- SCAN (NCT07280845)
- Where
- Sweden
- Volunteers
- 19,977 people
- Sponsor
- Linkoeping University
Post Operative Pain, Laparoscopic Sleeve Gastrectomy
Effects of Assisted Robotic vs Laparoscopic Sleeve Gastrectomy
This will be a prospective, obesity-registry based, single-blind randomized controlled trial with a 1:1 allocation ratio. Specific inclusion criteria are all patients eligible to undergo a Laparoscopic sleeve gastrectomy (LSG)…
- Conditions
- Post Operative Pain, Laparoscopic Sleeve Gastrectomy, Robotic Sleeve Gastrectomy, Obesity
- Trial name
- EARLY (NCT06425016)
- Testing
- Laparoscopic Sleeve Gastrectomy (LSG), Robotic Sleeve Gastrectomy (RSG)
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Ricard Corcelles
Bariatric Surgery, Sleeve Gastrectomy
Role of Dietary Habits in Efficacy of Bariatric Surgery - Study A
The purpose of the study is to evaluate how dietary habits in the post-surgical year impact outcomes of bariatric surgery.
- Conditions
- Bariatric Surgery, Sleeve Gastrectomy, Obesity
- Trial name
- NCT03470558
- Testing
- Dietary habits
- Where
- United States
- Volunteers
- 290 people
- Sponsor
- Brigham and Women's Hospital
Bariatric Surgery, Sleeve Gastrectomy
Role of Dietary Habits in Efficacy of Bariatric Surgery - Study C
The purpose of the study is to test how dietary habit interventions affect patients weight loss outcomes after bariatric surgery.
- Conditions
- Bariatric Surgery, Sleeve Gastrectomy, Obesity
- Trial name
- NCT03482986
- Testing
- Dietary habits plan
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Brigham and Women's Hospital
Bariatric Surgery, Sleeve Gastrectomy
Role of Dietary Habits in Efficacy of Bariatric Surgery - Study B
The purpose of the study is to compare dietary habits after bariatric surgery in patients with poor weight loss versus good weight loss outcomes.
- Conditions
- Bariatric Surgery, Sleeve Gastrectomy, Obesity
- Trial name
- NCT03467906
- Testing
- In-laboratory assessment
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Brigham and Women's Hospital
Obesity, Morbid Obesity
Comparing Dumping Symptoms and Quality of Life 6 Months After Sleeve Gastrectomy With or Without Transit Bipartition in Adults With Obesity
This clinical study aims to compare two types of bariatric (weight loss) surgery used to treat obesity: sleeve gastrectomy alone and sleeve gastrectomy with transit bipartition.
- Conditions
- Obesity, Morbid Obesity, Dumping Syndrome, Postgastrectomy Syndrome
- Trial name
- STuD-QoL (NCT07263269)
- Testing
- Sleeve Gastrectomy, Sleeve Gastrectomy with Transit Bipartition
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Mina Kamal Gergis Erian
Non-alcoholic Steatohepatitis (NASH), Endoscopic Sleeve Gastroplasty
A Physiologic Analysis of Endoscopic Sleeve Gastroplasty (ESG)
Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease worldwide. Affecting approximately one-third of the United States (U.S.) population, the prevalence of NAFLD increases to 90% in patients with…
- Conditions
- Non-alcoholic Steatohepatitis (NASH), Endoscopic Sleeve Gastroplasty, Non-alcoholic Fatty Liver Disease (NAFLD), Endoscopic Ultrasound
- Trial name
- NCT04820036
- Testing
- Insulin Resistance, Quality of Life Assessment, Liver Function Test
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Brigham and Women's Hospital