Clinical trials: Sleep Disorders
Insomnia, Alcohol Use, Unspecified
Research Evaluating Sleep & Trends for Universal Prevention
This study is designed to develop an integrated intervention to reduce alcohol and marijuana use and consequences and improve sleep among young adults with comorbid heavy episodic drinking, marijuana use, and sleep impairment.
- Conditions
- Insomnia, Alcohol Use, Unspecified, Marijuana Use
- Trial name
- REST-UP (NCT04783519)
- Testing
- Brief Behavioral Therapy for Insomnia (BBTI), Brief Alcohol Screening and Intervention for College Students (BASICS)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Washington
Insomnia
Reducing Health Disparities for Black Women in the Treatment of Insomnia
Black women are at a higher risk of developing insomnia than other women and insomnia has profound adverse physical and psychological health consequences.
- Trial name
- NCT03613519
- Testing
- SHUTi, modified SHUTi (i.e., SHUTi-BWHS), Patient education
- Where
- United States
- Volunteers
- 333 people
- Sponsor
- Boston University
Restless Legs Syndrome (RLS)
Intravenous Iron in the Management of Drug-resistant Restless Legs syndromeI
The pathophysiology of restless legs syndrome (RLS) is not well understood: it is thought to involve intracerebral iron deficiency and dopaminergic dysregulation.
- Trial name
- IRON-RLS (NCT07822607)
- Testing
- Ferric Carboxymaltose Injection [Ferinject], Randomization, Questionnaire and Physical Exam
- Where
- France
- Volunteers
- 66 people
- Sponsor
- University Hospital, Montpellier
Dementia, Sundowning
Aromatherapy Formulas for Sundowning and Sleep Quality in Patients With Dementia.
Dementia is common in aging societies and is often accompanied by sundowning syndrome and sleep problems. These symptoms can be very distressing for patients and place a heavy burden on family members and professional caregivers.
- Trial name
- AROMA-SUN (NCT07288736)
- Testing
- Aromatherapy Formula A, Aromatherapy Formula B
- Where
- 2 sites in Taiwan
- Volunteers
- 35 people
- Sponsor
- National Cheng-Kung University Hospital
Liver Transplant Disorder, Sleep
The Effect Of Therapeutic Touch and Music Rest on Sleeping Applied to Children With Liver Transplantation
Today, the demand for liver transplantation is increasing day by day, since liver transplantation is considered the most effective treatment for end-stage liver disease.
- Trial name
- NCT05108636
- Testing
- Therapeutic Touch, Music Rest
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Maksude YILDIRIM
Sleep Apnea
Safety and Efficacy Study of Sivopixant, Acetazolamide and SASS-001 in Sleep Apnea
The primary purpose of this study is to evaluate the effectiveness of sivopixant, acetazolamide and SASS-001 in adults with sleep apnea with a central component.
- Trial name
- NCT06776432
- Testing
- Sivopixant, Acetazolamide, SASS-001
- Where
- 9 sites in United States
- Volunteers
- 60 people
- Sponsor
- Shionogi
Insomnia
A 2-Part Single Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of E2006
Part A: The purpose of this study is to evaluate the safety and tolerability of single oral doses of E2006 administered in the morning to healthy male and female subjects.
- Trial name
- NCT01463098
- Testing
- E2006 1.0 mg, E2006 2.5 mg, E2006 5.0 mg
- Where
- 2 sites in United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Eisai Inc.
CDKL5
Targeting the Gut to Improve Seizure Control in CDKL5 Deficiency Disorder (CDD)
Standard anti-seizure medications have limited efficacy in seizure control in cyclin-dependent kinase-like 5 deficiency disorder (CDD).
- Trial name
- NUTRIENT (NCT06448663)
- Testing
- alpha-lactalbumin, fructooligosaccharides, inulin, alpha-lactalbumin, sodium butyrate, fructooligosaccharides, inulin
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- University of Milan
Sleep Apnea, Obstructive
The PREDICTOR Study: Assessing Diagnostic Predictors of Airway Collapse in Patients With Obstructive Sleep Apnea
This study is an exploratory, multicenter study of up to 300 subjects diagnosed with obstructive sleep apnea who are being evaluated for airway surgery.
- Trial name
- PREDICTOR (NCT05428839)
- Testing
- Pharyngeal width measurement
- Where
- 10 sites in United States
- Volunteers
- 300 people
- Sponsor
- Inspire Medical Systems, Inc.
REM Sleep Measurement
Postoperative Sleep Disturbances After Fast Track Hip and Knee Replacement
The purpose of this study is to quantify the degree of sleep disturbances after hip or knee replacement surgery. Through polysomnographic monitoring the disturbances in sleep stages will be clarified.
- Trial name
- NCT01144130
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Sleepiness, Daytime, Fatigue
Lifestyle Medicine Strategies for Combating Sleepiness and Fatigue in Professional Drivers
Sleep has a number of health benefits, including memory and learning, vitality and energy as well as high quality of life levels.
- Conditions
- Sleepiness, Daytime, Fatigue, Sleep Disorders, Circadian Rhythm
- Trial name
- HighWay2Health (NCT05096130)
- Testing
- Lifestyle Medicine Strategies
- Where
- Greece
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Thessaly
Tonsillar Hypertrophy, Sleep Apnea, Obstructive
Intracapsular Tonsillectomy in the Treatment of Obstructive Sleep Apnea in Adults
Treating sleep apnea in adults caused by tonsillar hypertrophy with intracapsular tonsillectomy by coblation
- Trial name
- NCT04314492
- Testing
- Tonsillectomy
- Where
- 2 sites in Finland
- Volunteers
- 25 people
- Sponsor
- Turku University Hospital
Obstructive Sleep Apnoea, Hypertension
Ambulatory Versus Home Blood Pressure Monitoring in Obstructive Sleep Apnea
Subjects referred to a sleep clinic had polysomnography (PSG), clinic BP measurements, 24-hour ABP monitoring and HBP monitoring using a device (Microlife WatchBP HomeN) that allows daytime (3 days, 2 duplicate readings/day) and…
- Trial name
- OSA (NCT01685736)
- Where
- 2 sites in Greece
- Volunteers
- 50 people
- Sponsor
- University of Athens
Postoperative Pain
The Effect of Esketamine on Postoperative Pain Relief in Patients Undergoing Laparoscopic Surgery
The purpose of this study is to investigate whether continuous intraoperative infusion of esketamine combined with the addition of esketamine to postoperative PCIA can improve postoperative pain and sleep quality in patients…
- Trial name
- NCT06300944
- Testing
- saline, Esketamine
- Where
- China
- Volunteers
- 100 people
- Sponsor
- General Hospital of Ningxia Medical University
Shared Decision Making, OSA - Obstructive Sleep Apnea
How "Shared Decision Making Decision-aid" Help Patients With Obstructive Sleep Apnea to Choose Treatment Plan
Shared decision-making helps patients to establish a treatment plan with clinicians together. Our goal was to determine if the tools we developed could reduced decisional conflict for patients with obstructive sleep apnea.
- Trial name
- NCT04076332
- Testing
- Decision aid
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Cardiovascular Diseases
A Study of Sleep Patterns to Determine Predictive Markers Due to Cardiovascular Disease in Elderly Patients
The purpose of this study is to learn if there are predictive markers of hospitalization or death that can be found from data gathered from a Sleep Number® bed.
- Trial name
- NCT05749263
- Where
- 2 sites in United States
- Volunteers
- 13 people
- Sponsor
- Mayo Clinic
Anxiety, Insomnia
Impact of Patient Education on Benzodiazepine Use in the Elderly
The overall goal of this research is to develop and test strategies to decrease potentially inappropriate medication use among the elderly.
- Trial name
- NCT02478593
- Testing
- Educational booklet
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Vermont
Sleep Deprivation
Evaluation of the Effect of Neurofeedback Targeting EEG Theta / Beta Activities on the Strengthening of Wakefulness Maintenance Capacities and Cognitive Performance.
Neurofeedback is a cognitive remediation technique that allows a subject to learn to regulate their cognitive and brain activity through information provided in real time about their brain activity, in particular…
- Trial name
- NEUROWAKE (NCT04591314)
- Testing
- Neurofeedback
- Where
- France
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Neuropathic Pain, Insomnia
Sleep and Neuropathic Pain - Intervention Study on Pregabalin
The goal of this clinical study is to study sleep and its microstructure in neuropathic pain patients who have or who do not have a clinically significant sleep disturbance, before and during (after 1-month stabile dosage)…
- Conditions
- Neuropathic Pain, Insomnia, Sleep Disorder
- Trial name
- NCT06155916
- Testing
- Pregabalin
- Where
- 2 sites in Finland
- Volunteers
- 40 people
- Sponsor
- Helsinki University Central Hospital
Muscle Pain, Feedback, Psychological
Evaluation of Biofeedback Therapy Efficiency in Masticatory Muscles Pain Management
This study evaluates beneficial effects of biofeedback therapy in reducing pain and increased tension of muscles occurring in patients with temporomandibular disorders (TMD).
- Conditions
- Muscle Pain, Feedback, Psychological, Craniomandibular Disorders, Temporomandibular Disorder
- Trial name
- NCT03421028
- Testing
- Electromyography Biofeedback, Classic treatment for myogenous TMD
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Wroclaw Medical University