Clinical trials: Sleep Disorders, Circadian Rhythm
Sleep, Sleep Disorders, Circadian Rhythm
Effects of Delayed School Start Times on Sleep, Mental Health, and Academic Performance Among Norwegian Adolescents
The aim is to investigate whether later school start times have positive effects on high school students' sleep patterns, mental health and daytime functioning.
- Conditions
- Sleep, Sleep Disorders, Circadian Rhythm, Psychiatric Disorder, Sleepiness, Daytime
- Trial name
- NCT06657482
- Testing
- Delayed school start time
- Where
- Norway
- Volunteers
- 583 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Blindness
Young Blind Child Melatonin Treatment Study
The primary goal of this study is to identify the presence of desynchronized circadian rhythms in 25 children by measuring melatonin secretion in serial blood or saliva samples, and to rule out any primary sleep disorders.
- Trial name
- NCT00688935
- Testing
- Melatonin
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Oregon Health and Science University
Bipolar Disorder, Time Restricted Eating
Healthy Lifestyles in Bipolar Disorder: Bay Area Study
The goal of this clinical trial is to understand how level of adherence with time-restricted eating (TRE) predicts change in diurnal rhythms (as measured using the amplitude of diurnal peripheral clock gene expression), and how…
- Trial name
- NCT06555406
- Testing
- Time-restricted eating for 8 weeks
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of California, Berkeley
Autism Spectrum Disorder
Do Sleep and Circadian Rhythm Disturbances Impact the Cognitive and Behavioural Development of Children With Autism?
The primary objective of this study is to undertake a longitudinal investigation of the impact of sleep and circadian rhythm disturbances on cognitive and behavioural trajectories in children with autism spectrum disorder (ASD)…
- Trial name
- NCT02878499
- Testing
- polysomnography
- Where
- 5 sites in France
- Volunteers
- 105 people
- Sponsor
- University Hospital, Strasbourg, France
Alzheimer's Disease
Effect of Therapeutic Light on Sleep, Circadian Rhythm, and Global Function in Women With Alzheimer's
Determine effect and duration of effect of timed therapeutic light compared to control light on parameters of circadian rhythmicity, physiologic plasticity, sleep, and global function in women with Alzheimer's Disease.
- Trial name
- NCT02502045
- Testing
- Morning Simulated Sunlight, Non-therapeutic Red Light
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Yale University
Lung Adenocarcinoma, Sleep Disorders, Circadian Rhythm
Sleep State in Lung Cancer: A Retrospective Analysis
Lung cancer remains the leading cause of cancer-related mortality globally, with tumor progression closely linked to the immune microenvironment.
- Trial name
- NCT06953492
- Testing
- PSQI
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Shanghai Zhongshan Hospital
Circadian Dysrhythmia, Sleep Disturbance
PICU-related Sleep and Circadian Dysregulation Pilot Study
A single center pilot trial investigating the feasibility of using actigraphy and salivary melatonin levels to measure the sleep and circadian rhythm of critically ill children aged 3 to 6 years old.
- Conditions
- Circadian Dysrhythmia, Sleep Disturbance, Critical Illness, Children, Only
- Trial name
- NCT06505447
- Testing
- Daytime light exposure, Daytime restricted feeding
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- State University of New York at Buffalo
Shift Work Disorder, Shift Work Type Circadian Rhythm Sleep Disorder
Circadian Rhythm and Health in Heavy Industry Shift Workers
Shift work can disrupt the body's circadian rhythm, which may negatively affect sleep, musculoskeletal health, and quality of life.
- Trial name
- NCT07702344
- Testing
- Questionnaire-Based Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 226 people
- Sponsor
- Istanbul Gedik University
Hypertension, Cardiovascular Risk Factor
Sleep and Circadian Mechanisms of Non-dipping Blood Pressure
This study will be the first to distinguish the relative contributions of sleep, circadian and behavioral mechanisms to the non-dipping BP profile in Black adults and will lay the groundwork for optimizing therapies dependent on…
- Trial name
- NCT03558893
- Testing
- Forced Desynchrony
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Pain, Back, Pain, Acute
Relieving Pain and Improving Sleep: Evaluating Topical Pain Relief and Sleep Patches
This minimal risk, randomized, double-blind, placebo controlled Institutional Review Board (IRB)-approved study with functional measurements, will evaluate pain relief and sleep improvement after use of a drug- free, non-invasive…
- Conditions
- Pain, Back, Pain, Acute, Sleep Disorder, Sleep Disorders, Circadian Rhythm
- Trial name
- RESTORE (NCT06505005)
- Testing
- Drug- free, non-invasive patch (FREEDOM or REM Patch) with haptic vibrotactile trigger technology (VTT) Other Names:
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- SuperPatch Limited LLC
Circadian Rhythm Sleep Disorders
Safety and Efficacy of VEC-162 on Circadian Rhythm in Healthy Adult Volunteers
The purpose of this study is to assess the safety and efficacy of VEC-162 compared to matching placebo on circadian phase shift and sleep parameters.
- Trial name
- NCT00490945
- Testing
- VEC-162
- Where
- 2 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Vanda Pharmaceuticals
Circadian Rhythm Sleep Disorder, Unspecified
Feasibility Pilot of Bright Light in the Intensive Care Unit
To evaluate the feasibility of providing daytime bright light in the ICU in a pilot randomized controlled trial.
- Trial name
- NCT03568045
- Testing
- standard light, 10,000 lux bright light, 4 hours, 10,000 lux bright light, 8 hours
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Yale University
Nursing, Hemodialysis Patient
THE EFFECTS OF CIRCADIAN RHYTHM-BASED PROGRESSIVE RELAXATION EXERCISES IN HEMODIALYSIS PATIENTS
The aim of this study is to determine the effect of Progressive Relaxation Exercise (PGE) applied according to the circadian rhythms of hemodialysis (HD) patients on symptom management, sleep quality, comfort and mental…
- Conditions
- Nursing, Hemodialysis Patient, Circadian Rhythm, Relaxation Exercise
- Trial name
- NCT07499297
- Testing
- Progressive Relaxation Exercises
- Volunteers
- 75 people
- Sponsor
- Karamanoğlu Mehmetbey University
Smith-Magenis Syndrome, Autism Spectrum Disorder
Smith Magenis Syndrome and Autism Spectrum Disorders
Autism Spectrum Disorders (ASD) are a neurodevelopmental disorder. Their prevalence is estimated at around 0.4% of the general population worldwide.
- Trial name
- SMS/TSA (NCT05116904)
- Testing
- Assessment
- Where
- 2 sites in France
- Volunteers
- 40 people
- Sponsor
- Hospices Civils de Lyon
Circadian Rhythm Sleep-Wake Disorder
Evaluating the Effectiveness of Intervention Based on the Model of Occupational Harmony in Patients With Sleep Disorders
The goal of this clinical trial is to learn the effectiveness of an intervention based on the Model of Occupational Harmony (MOHar) in treating patients with sleep disorders.
- Trial name
- NCT06558929
- Testing
- Occupational Therapy, Conventional Treatment
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Peking University First Hospital
Major Depressive Disorder, Bipolar I Disorder
Digital Phenotypes for Predicting Depression_Validation
This 12-month, single-site prospective observational study will prospectively monitor the recurrence of mood episodes while continuously collecting passive digital phenotypes in individuals with and without mood disorders.
- Conditions
- Major Depressive Disorder, Bipolar I Disorder, Bipolar II Disorder, Mood Disorders
- Trial name
- NCT07880015
- Where
- South Korea
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Korea University Anam Hospital
Obstructive Sleep Apnea of Adult
Melatonin's Effect on Nighttime Blood Pressure and Sleep in OSA Patients (MEBP-OSA)
The goal of this clinical trial is to learn if melatonin works to treat comorbid insomnia in adults with OSA and nocturnal non-dipping blood pressure pattern.
- Trial name
- MEBP-OSA (NCT06380491)
- Testing
- Melatonin 3 MG Oral Tablet
- Where
- Mexico
- Volunteers
- 50 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Sleep Disorders, Sleep Apnea, Obstructive
Sleep Disorders Management, Health and Safety in Police
The purpose of the study is to test the effect of a sleep disorders detection and treatment program for police officers on their safety, quality of life, and job performance. The program is called Operation Healthy Sleep.
- Conditions
- Sleep Disorders, Sleep Apnea, Obstructive, Restless Legs Syndrome, Sleep Disorders, Circadian Rhythm
- Trial name
- NCT00207285
- Testing
- Sleep Hygiene Education, Screening and Treatment of Sleep Disorders
- Where
- United States
- Volunteers
- 731 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Sleep Deprivation, Circadian Rhythm Disorders
Prevalence and Affecting Factors of Sleep and Circadian Rhythm Disorders in ICU
Most ICU patients experience sleep and circadian disruption (SCD), which causes a profound negative impact on patients, such as prolonged mechanical ventilation, glucose intolerance, and the occurrence of delirium.
- Conditions
- Sleep Deprivation, Circadian Rhythm Disorders, Critical Illness
- Trial name
- NCT06346613
- Where
- China
- Volunteers
- 56 people
- Sponsor
- Shanghai Zhongshan Hospital
Critical Illness, Delirium
Electroencephalography and Sleep Quality With Lormetazepam in the Intensive Care Unit
The goal of this clinical trial is to test the effect of continuous lormetazepam infusion on EEG patterns in critically ill patients who are given continuous infusion of lormetazepam in an intensive care unit setting.
- Conditions
- Critical Illness, Delirium, Sleep Disorders, Circadian Rhythm
- Trial name
- CLIO-ICU (NCT06473415)
- Testing
- Electroencephalography
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Charite University, Berlin, Germany