Clinical trials: Sleep Architecture
MDMA Discontinuation Syndrome
Study of the Effects of MDMA/Ecstasy on Water Regulation, Sleep, and Cognition.
The purpose of this study is to measure the effects of MDMA on sleep, mood, thinking, and how your body retains water. The researchers are interested in the effects that occur a few hours after taking MDMA as well as effects…
- Trial name
- 2C (NCT01053403)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- California Pacific Medical Center Research Institute
Postpartum Women
Sleep Architecture as a Digital Biomarker for Postpartum Depression in Hong Kong Mothers
The goal of this study is to develop a postpartum depression (PND) Risk index using the UK Biobank dataset, and to validate the risk index in Hong Kong postpartum women.
- Trial name
- SLEEP-PD-HK (NCT07600593)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Sleep Bruxism, Adult
Sleep Architecture and Factors Associated With Definitive Diagnosis of Sleep Bruxism
This case-control study will evaluates the association between the definitive sleep bruxism diagnosis by gold-standard polysomnography examination obtained at Pelotas Sleep Institute and the sociodemographic, occupational…
- Trial name
- NCT03825237
- Testing
- Polysomnography
- Where
- Brazil
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Sleep
Acute Effect of Exogenous Ketosis on Sleep Architecture Following Strenuous Exercise
The aim of this study is to investigate the effect of oral ketone ester administration on sleep architecture. To investigate this, the investigators use a randomised, placebo-controlled, cross-over research design.
- Trial name
- NCT05439720
- Testing
- Ketone ester, Exercise
- Where
- Belgium
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Substance-Related Disorders, Substance Use Disorder
Sleep Architecture, Cognitive Function, and Quality of Life During Early Recovery From Substance Use Disorder
This prospective cohort study investigates how sleep disturbances affect cognitive recovery and quality of life during early recovery from substance use disorder (SUD).
- Conditions
- Substance-Related Disorders, Substance Use Disorder, Sleep Wake Disorders, Cognitive Dysfunction
- Trial name
- NCT07852052
- Volunteers
- 34 people
- Sponsor
- Assiut University
Alzheimer's Disease, Early Alzheimer's Disease
A Study to Compare Two Different Sleep Tests in Participants With No Symptoms or Early Symptoms of Alzheimer's Disease
The purpose of this study is to compare the results of two different sleep tests in Alzheimer's patients with no symptoms or early symptoms.
- Conditions
- Alzheimer's Disease, Early Alzheimer's Disease, Memory Problems
- Trial name
- NCT07485153
- Testing
- Mobile EEG, Activity Monitor, Sleep Study
- Where
- Singapore
- Volunteers
- 35 people
- Sponsor
- Eli Lilly and Company
Depression / Major Depressive Disorder, Depressed Mood
REM Sleep Disruption and Its Potential Uses in Depression Management
This randomized study evaluated whether brief wrist vibrations delivered through an Apple Watch during algorithm-identified rapid eye movement (REM) sleep could reduce depressive symptoms over approximately four weeks.
- Trial name
- NCT07891806
- Testing
- REM-Contingent Smartwatch Haptic Stimulation, Smartwatch Sleep Monitoring and Smart Alarm
- Where
- 2 sites in Romania
- Volunteers
- 208 people
- Sponsor
- WAKEZ HEALTH TECH ECOSYSTEM SRL
Critical Illness, ICU
Effects of Melatonin on Sleep Architecture of Critically Ill Patients in the ICU
This is a pilot study to examine the effects of melatonin on the sleep patterns of critically ill patients. Patients will have their sleep patterns measured with a device attached to their head with a headband then be given a…
- Conditions
- Critical Illness, ICU, ICU Hospitalization, Melatonin
- Trial name
- NCT07691996
- Testing
- Melatonin
- Volunteers
- 30 people
- Sponsor
- Rutgers, The State University of New Jersey
Sleep, Emotion
The Effects of Acute vs. Chronic of Screen Illumination on: Sleep Efficacy and Architecture, Physiology, Emotion and Behavior: Possible Effect on Human Health
The human eye has a dual role, which is reflected by the various photo-receptors used for vision of images and colors ,Image forming photoreceptors (IFP) and for entrainment of our "Biological clock" located in the hypothalamus…
- Trial name
- NCT02839395
- Testing
- No intervention- base line, Acute, Chronic
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Assuta Medical Center
Anorexia Nervosa
Sleep Quality and Biomarkers in Adolescent Girls With Anorexia Nervosa
The purpose of this observational study is to systematically evaluate how a 12-month multimodal psychiatric treatment program affects sleep quality, inflammatory and hormonal biomarkers, eating disorder psychopathology, and…
- Trial name
- NCT07644728
- Testing
- Longitudinal Fasting Blood Sampling for Biomarker Assessment, Multimodal Psychiatric Treatment Program, Home Polysomnography - NOX A1
- Volunteers
- 25 people
- Sponsor
- University of Split, School of Medicine
Insulin Resistance
Effects of Sleep Duration and Architecture on Insulin Sensitivity
This pilot clinical trial will test the hypotheses that sleep restriction (for 5 nights), in comparison to "normal sleep", will: 1.
- Trial name
- NCT01396941
- Testing
- Sleep restriction
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Epilepsy, Nocturnal Enuresis
Sleep Architecture in Valproate-induced Nocturnal Enuresis in Primary School and Preschool Children.
Our study, retrospectively evaluate the characteristics of and the risk factors for the occurrence of nocturnal enuresis in epileptic children kept on valproate monotherapy.
- Trial name
- NCT04191863
- Testing
- Clinical, EEG and laboratory assessment at presentation, Valproate
- Where
- Egypt
- Volunteers
- 260 people
- Sponsor
- Mansoura University Hospital
Tourette's Syndrome, Attention Deficit Hyperactivity Disorder
Study of Clonidine on Sleep Architecture in Children With Tourette's Syndrome (TS) and Comorbid ADHD
In the present study, we examine the question "Will day-time aggression in children improve when their night-time sleep is treated with pharmacological intervention (i.e.
- Trial name
- NCT00152750
- Testing
- APO-clonidine
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Bruxism, Sleep-Related
Smartwatch Analysis of Sleep Bruxism
This study aims to investigate the differences in sleep stages and total sleep duration between individuals diagnosed with sleep bruxism and healthy controls.
- Trial name
- NCT07453121
- Testing
- Smartwatch-based Sleep Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Cappadocia University
HIV
Sleep and Cognition After Atripla to Stribild Switch
Atripla and Stribild are two FDA-Approved one pill a day combination antiretroviral medications given for the treatment of HIV. Both drugs are reasonably well tolerated.
- Trial name
- NCT02283060
- Testing
- Stribild, Atripla
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Hawaii
Insomnia, Sleep Fragmentation
Suvorexant and Sleep/Delirium in ICU Patients
Investigators will evaluate the efficacy of postoperative oral suvorexant treatment on nighttime wakefulness after persistent sleep onset (WASO) among adult cardiac surgical patients recovering in the cardiac intensive care unit…
- Conditions
- Insomnia, Sleep Fragmentation, Sleep Initiation and Maintenance Disorders, Postoperative Delirium
- Trial name
- NCT04092894
- Testing
- Suvorexant 20 mg
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Beth Israel Deaconess Medical Center
Depression, Bipolar
An Investigation of Sleep Architecture in Ziprasidone-Treated Bipolar Depression
This study uses polysomnographs(PSG) to investigate sleep patterns in patients with bipolar depression. This is a double-blind, placebo-controlled, study of ziprasidone that is added to patients current medications.
- Trial name
- NCT00835107
- Testing
- ziprasidone hydrochloride
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- Queen's University
Brain Age
Brain Age and Sleep Architecture in Meditators
This is a single-center, cross-sectional study that will recruit approximately fifty seven (57) meditators and fifty one (51) controls.
- Trial name
- BRANCH (NCT05513846)
- Testing
- DREEM EEG Device, SleepImage Ring
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Sleep Deprivation
Effects of Sleep Deprivation and Recovery on Cognitive Functions
This study will measure brain activity in individuals performing language tasks while in various states of alertness to learn more about how the central nervous system is affected by impairments such as sleepiness.
- Trial name
- NCT00179322
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- National Institute on Deafness and Other Communication Disorders (NIDCD)
Narcolepsy in Children
Pediatric Cohort Study
Narcolepsy is a rare disease that affects 0.05% of the general population. It is characterized by a dysregulation of the sleep wake regulation that leads to uncontrolled sleep episode during day and a disorganized sleep during…
- Trial name
- COSACM (NCT04561427)
- Testing
- Study of Sleep architecture in children with narcolepsy
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Hospices Civils de Lyon