Clinical trials: Skin Preparation
Birch Pollen Allergy
Physiological Study to Determine the Allergic Skin Activity After Different Skin Preparation
The objectives of this monocentric investigator initiated exploratory clinical trial is to optimize allergen delivery across the epidermal barrier.
- Trial name
- NCT01628484
- Testing
- prick lancet, Tape stripping, Microneedle
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- University of Zurich
Surgical Skin Preparation
In-vivo Efficacy of Patient Preoperative Prep
The objective of the study is to demonstrate the antimicrobial efficacy of the ZP Preoperative Prep on skin flora of the abdomen and inguinal regions of human subjects.
- Trial name
- NCT02831998
- Testing
- ZuraPrep, ChloraPrep, ZP Vehicle
- Where
- United States
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Zurex Pharma, Inc.
Melasma
Comparative Study of Dual Yellow Laser Versus Stabilized Kilnman Preparation in the Treatment of Melasma
Recent data highlight the role of vascularity in melasma and a recent study showed the interest to target this vascular component by pulsed dye laser.
- Trial name
- NCT01850186
- Testing
- Dual yellow Laser, Stabilized kilnman trio
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Propionibacterium Infection
Does the Addition of Hydrogen Peroxide to Chlorhexidine Skin Prep to Treat P. Acnes in the Shoulder
This is a prospective, randomized controlled trial to evaluate the ability of hydrogen peroxide preparation in addition to chlorhexidine to decrease the colonization of Propionibacterium acnes(a bacteria commonly found in the…
- Trial name
- NCT03656588
- Testing
- a. Standard iodine scrub, 3% hydrogen peroxide prep, follow by ChloraPrep (2% chlorhexidine gluconate and 70% isopropyl alcohol, Iodine scrub and ChloraPrep alone
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Rothman Institute Orthopaedics
HIV Infections
Surveillance and Medical Help for HIV-infected Intravenous Drug Users in and Out of Prison
It is difficult to detect the intestinal protozoal infections among the HIV-infected persons or travelers diarrhea by using the traditional microscopy or staining methods.
- Trial name
- NCT00739258
- Where
- Taiwan
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Intact Skin
Open-Label Test of the HM242 Medical Devices to Evaluate Safety and Local Tolerability
It is the first clinical study aimed at assessing the safety and tolerability of HM242-Solution and HM242-Gel after their application under occlusion on intact skin. The HM242-Solution is intended for chronic wounds (e.g.
- Trial name
- NCT04192123
- Testing
- HM242
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- B. Braun Ltd. Centre of Excellence Infection Control
Rheumatoid Arthritis
Investigating the Effects of the Digital App Rheumabuddy4.1 in a Clinical RCT Set-up in Patients With Rheumatoid Arthritis
Rheumatoid arthritis (RA) is one of the most frequently occurring autoimmune rheumatic diseases, affecting an estimated 1% of the global population.
- Trial name
- NCT06337786
- Testing
- Digital app RB4.1, Control arm
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- Henning Bliddal
Preoperative Skin Preparation
Evaluation of the Antimicrobial Effectiveness of an Antimicrobial Cloth
Healthy volunteers will receive treatment to two body locations with the investigational product and placebo and the antimicrobial effectiveness of each treatment will be measured.
- Trial name
- NCT03229759
- Testing
- Octenidine Dihydrocloride in aqueous solution, Vehicle Control, Saline Control
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Becton, Dickinson and Company
Cutibacterium Acnes Infection
Optimization of Skin Preparation to Reduce Cutibacterium Acnes Colonization in Superficial and Deep Samples During Prosthetic Shoulder Surgery in Male Patients
Infections on joint replacements remain one of the most serious complications of orthopaedic surgery. Despite improvements in skin preparation and antibiotic prophylaxis procedures, the risk of infection of joint prosthesis is…
- Trial name
- OPRICA (NCT04028401)
- Testing
- 5% benzoyl peroxide
- Where
- 6 sites in France
- Volunteers
- 110 people
- Sponsor
- Nantes University Hospital
Infectious Disease
Pilot Clinical Trial - Comparative Study of Two Material Concentration of OD-141309
A sufficient number of subjects will be entered into testing to complete 42 subjects per each of the 2 test and 2 control configurations.
- Trial name
- Odysseus-01 (NCT04703335)
- Testing
- Antimicrobial efficacy of gel ZHCK4 as a patient preoperative skin preparation
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Zaycor Healthcare Corp
Orthopedic Surgery
Efficacy of CHX Cloths Versus CHX Soaps for Bathes Before Orthopedic Surgery
Surgical site infections (SSI) in orthopedic surgery are rare events but associated with great morbidity as well as a significant additional cost.
- Trial name
- POL (NCT05120739)
- Testing
- 2% CHX cloths
- Where
- France
- Volunteers
- 64 people
- Sponsor
- University Hospital, Grenoble
Ulcer Foot, Mellitus Diabetes
The Prospective, Double-blind, Multicenter, Placebo-controlled, Randomized, Comparative Clinical Trial
The main objective of the study is to evaluate the efficacy and safety of Neovasculgen® in a course dose of 2.4 mg in combination with standard drug therapy in patients with unilateral neuroischemic form of diabetic foot syndrome.
- Trial name
- NCT07391319
- Testing
- Neovasculgen®
- Where
- Russia
- Volunteers
- 144 people
- Sponsor
- JSC NextGen
Surgical Skin Preparation
In-vivo Efficacy of Patient Preoperative Prep, ZuraPrep (ZP)
The objective of the study is to demonstrate the antimicrobial efficacy of the Zurex Preoperative Prep (ZuraPrep - clear) on skin flora of the abdomen and inguinal regions of human subjects.
- Trial name
- ZP (NCT03782103)
- Testing
- ZuraPrep Clear Solution, ChloraPrep, ZuraPrep Vehicle
- Where
- United States
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Zurex Pharma, Inc.
Venous Leg Ulcer (VLU)
An Open Label, Single Treatment, Single Arm, Multiple Dose Phase-2 Study to Evaluate the Pharmacokinetics, Safety, and Clinical Performance of EscharEx (EX-03) in Participants With Venous Leg Ulcers
This is a pharmacokinetics (PK) study - the main objective of this study is to assess the PK, safety and clinical performance of 5% EscharEx (EX-03 formulation) in debridement of Venous Leg Ulcers
- Trial name
- NCT07692178
- Testing
- EX-03
- Volunteers
- 20 people
- Sponsor
- MediWound Ltd
Plantar Wart
Pyruvic Acid Versus Salicylic Acid Preparation in Treatment of Plantar Warts
Plantar warts can be bothersome and painful requiring treatment. The investigators will compare the efficacy of pyruvic acid and salicylic acid in treating multiple plantar warts.
- Trial name
- NCT02151630
- Testing
- Pyruvic acid, Salicylic Acid
- Where
- Iran
- Volunteers
- 60 people
- Sponsor
- Isfahan University of Medical Sciences
Acne Vulgaris
Effect of New Topical Preparation for Treatment of Acne Vulgaris
The investigators propose a randomized, double-blind control trial study to evaluate the efficacy and safety of the optimized topical combination ME of the investigated drugs in the treatment of acne vulgaris containing DAP-FLU…
- Trial name
- NCT05899699
- Testing
- DAP-FLU ME, Adapalene .1% gel
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Mansoura University
Breast Cancer, Triple Negative Breast Cancer (TNBC)
Biolosion Combined Standard Neoadjuvant Therapy to Treat Triple-negative Breast Cancer
To evaluate the efficacy and safety of compound preparation Biolosion in combination with standard neoadjuvant therapy for locally advanced triple-negative breast cancer
- Conditions
- Breast Cancer, Triple Negative Breast Cancer (TNBC), Early Stage Breast Cancer, Immunotherapy
- Trial name
- NCT06768931
- Testing
- Biolosion (oral probiotic compound preparation)
- Where
- 5 sites in China
- Volunteers
- 192 people
- Sponsor
- Sun Yat-sen University
Surgical Skin Preparation
Clinical Evaluation of Patient Preoperative Prep
The objective of the study is to demonstrate the antimicrobial efficacy of the ZP Preoperative Prep on skin flora of the abdomen and inguinal regions of human subjects.
- Trial name
- NCT02831816
- Testing
- ZuraPrep, ChloraPrep, ZP Vehicle
- Where
- United States
- Volunteers
- 640 people, healthy volunteers welcome
- Sponsor
- Zurex Pharma, Inc.
Preoperative Skin Preparation
Effectiveness of an Antimicrobial Agent for Preoperative Skin Preparation
Objective of this study is to compare the antimicrobial properties of an investigational agent to an active control and a negative control when applied to specific body locations.
- Trial name
- NCT03224299
- Testing
- OCT - clear, OCT- tinted, ChloraPrep
- Where
- 2 sites in United States
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Becton, Dickinson and Company
Surgical Site Infection
Comparison of Iodine + Isopropyl Alcohol Versus Iodine + Antimicrobial Sealant for Skin Preparation
The purpose if this study is to determine whether a microbial sealant (iodine + cyanoacrylate) [InteguSEAL®, Kimberly-Clark] reduces surgical site infections when compared to iodine and isopropyl alcohol (povacrylex in isopropyl…
- Trial name
- NCT01110772
- Testing
- 2-octyl cyanoacrylate [InteguSEAL®], Iodine povacrylex in isopropyl alcohol [Duraprep®, 3M]
- Where
- Mexico
- Volunteers
- 1,200 people
- Sponsor
- National Institute of Cancerología