Clinical trials: Skin Preparation
Multiple Sclerosis
Single Center, Open Label, Study of Preparation H on Erythema in Relapsing MS Patients Treated With PLEGRIDY
The primary purpose of this single center, randomized, open label study in relapsing Multiple Sclerosis (MS) patients on PLEGRIDY (peginterferon beta-1a) is to assess the effect of Preparation H (phenylephrine) Maximum Strength…
- Trial name
- NCT02665221
- Testing
- No Treatment Arm, Topical Preparation H arm
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Skin Barrier Dysfunction, Healthy Volunteers
Effect of FPP on Cutaneous Barrier Integrity
This pilot study will test how Fermented Papaya Preparation (FPP) impacts overall TEWL of areas that commonly display diminished barrier function, such as the skin from face, arms, and hands.
- Trial name
- FPP OSATO (NCT07725835)
- Testing
- Fermented Papaya Preparation (FPP)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Propionibacterium Acnes
Propionibacterium Acnes in Shoulder Arthroplasty
The investigator's plan to determine whether pre-operative skin preparation with hydrogen peroxide alters rates of P acnes culture positivity.
- Trial name
- NCT03057821
- Testing
- 3% hydrogen peroxide
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of Utah
Diabetic Foot, Stem Cell
Stem Cell Derived Exome for Treatment of Diabetic Foot
This trial is designed to investigate the safety and efficacy of patients with diabetic foot by using stem cell derived exome.
- Trial name
- NCT06480123
- Testing
- Skin drug prepared with exome originated from stem cell
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Second Affiliated Hospital of Guangzhou Medical University
Wound Infection, Amputation Wound
The Amputation Surgical Site Infection Trial (ASSIT)
Lower limb amputations are performed usually as a last resort in patients with acute and chronic limb ischaemia (CLI) caused by vascular disease, poorly controlled diabetes or, infection.
- Trial name
- ASSIT (NCT02018094)
- Testing
- Co-amoxiclav, Iodine, Metronidazole
- Where
- United Kingdom
- Volunteers
- 160 people
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Prosthetic Joint Infection, Surgical Skin Infection
Efficacy of InteguSeal for Surgical Skin Preparation in Patients Undergoing Total Joint Replacement
This study is being conducted to investigate the potential benefits of using a special type of fluid that can be applied to the skin (Integuseal) in addition to standard surgical skin preparation in patients undergoing total hip…
- Trial name
- NCT00829556
- Testing
- Integuseal
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Rothman Institute Orthopaedics
Acne Vulgaris
Efficacy and Safety of a Preparation Containing an Antibiotic and Anti-Inflammatory Agent in Acne Vulgaris
The concept behind our study was to combine an effect of antibiotic and anti-inflammatory agents for a more efficient acne therapy directed at the factors involved in the pathophysiology of the disease.
- Trial name
- NCT00361322
- Testing
- clindamycin phosphate, salicylic acid
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Hadassah Medical Organization
Allergic Reactions, Allergic Skin Reaction
Determination of Blomia Tropicalis Allergen Extract in Prick Test Units
The primary objective is to assess the concentration of Blomia tropicalis allergenic extract that induces a wheal of size equivalent to that produced by a 10 mg/mL histamine dihydrochloride solution, in order to be used as…
- Trial name
- NCT07195929
- Testing
- Allergenic Extract
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Inmunotek S.L.
Uterine Fibroid, Myoma;Uterus
OPPIuM Technique and Myolysis With Diode Laser Dwls
PURPOSE OF THE STUDY The study aims to examine the feasibility and effectiveness of the OPPIuM technique combined with myolysis using the DWLS diode laser.
- Trial name
- Myolysis (NCT04748978)
- Testing
- hysteroscopy
- Where
- Italy
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Cagliari
Breast Cancer Female
Delayed Breast Reconstruction by Prepectoral Implant After Lipo-preparation (RM2prepec)
Breast implants associated with the installation of a complementary matrix (of dermal or synthetic origin), showed satisfactory results in term of post-operative follow-up but also aesthetic outcomes.
- Trial name
- RM2prepec (NCT04343820)
- Testing
- Breast reconstruction
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Institut Cancerologie de l'Ouest
Breast Cancer
Orall Administered Probiotics to Improve the Quality of the Vaginal Flora of Women With Breast Cancer and Chemotherapy.
The aim of this study is the improvement of the vaginal flora by at least two grades of the Nugent scale after application of oral probiotics.
- Trial name
- NCT01723592
- Testing
- Probiotics
- Where
- Austria
- Volunteers
- 27 people
- Sponsor
- Medical University of Vienna
Alopecia Areata
Role of Minoxidil in Alopecia Areata Transepidermal Drug Delivery of Minoxidil Via Either Fractional Carbon Dioxide Laser or Microneedling Versus Its Topical Nanoparticles Preparation for Treatment of Alopecia Areata
Compare the clinical efficacy, and safety of transepidermal drug delivery of fractional CO2 laser versus microneedling followed by minoxidil 5% application for the treatment of alopecia areata.
- Trial name
- NCT05587257
- Testing
- Fractional CO2 laser, Derma pen, Niosome minoxidil
- Volunteers
- 60 people
- Sponsor
- Assiut University
Healthy
Antimicrobial Efficacy of 2% CHG (Chlorhexidine Gluconate)
Pilot study to evaluate and compare activity of preoperative preparation with comparator
- Trial name
- NCT02530541
- Testing
- CHG
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Medline Industries
Skin Flora Contamination
Study of the Combination of a Cyanoacrylate and Surgical Solutions in Reducing Skin Flora Contamination
The purpose of this study is to determine if there is a qualitative reduction in microbial skin flora post-surgery compared to pre-surgery when a cyanoacrylate based microbial sealant is used in combination with a surgical skin…
- Trial name
- NCT00467857
- Testing
- InteguSeal* skin sealant and standard surgical preparation, Standard preoperative skin preparation
- Where
- 5 sites in United States, Brazil and 3 more
- Volunteers
- 293 people
- Sponsor
- Kimberly-Clark Corporation
Surgical Site Infection, Unplanned Fracture-Related Reoperation
Pre-operative Alcohol Skin Solutions in Fractured Extremities
The prevention of infection is an important goal influencing peri-operative care of extremity fracture patients. Standard practice in the operative management of extremity fractures includes sterile technique and pre-operative…
- Conditions
- Surgical Site Infection, Unplanned Fracture-Related Reoperation, Open Appendicular Fracture, Closed Lower Extremity Fracture
- Trial name
- PREPARE (NCT03523962)
- Testing
- DuraPrep, ChloraPrep
- Where
- 27 sites in United States, Canada
- Volunteers
- 8,485 people
- Sponsor
- University of Maryland, Baltimore
Venous Leg Ulcer (VLU)
A Double Blind Study Performed to Evaluate the Efficacy and the Safety of EscharEx in Debridement of VLU (VALUE)
The main objective of this study is: To assess the efficacy and safety of EscharEx (EX-03 5% formulation) compared to placebo control,in debridement and wound bed preparation of Venous Leg Ulcers (VLU).
- Trial name
- VALUE (NCT06568627)
- Testing
- EscharEx (EX-03)
- Where
- 60 sites in United States, Austria and 7 more
- Volunteers
- 216 people
- Sponsor
- MediWound Ltd
Skin Flora Bacterial Reduction Post-product Application
In-vivo Efficacy Study of Patient Preoperative Preps
The purpose of this study is to evaluate the antimicrobial efficacy of the 3M CHG/IPA Prep on skin flora of the abdominal and inguinal regions of human subjects.
- Trial name
- NCT01968356
- Testing
- 3M CHG/IPA Prep Colorless, 3M CHG/IPA Prep Tint, ChloraPrep
- Where
- United States
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Solventum US LLC
Segmental Vitiligo, Piebaldism
Autologous Cell Suspension Grafting Using ReCell in Vitiligo and Piebaldism Patients
The purpose of this study is to assess the efficacy and safety of ReCell grafting after CO2 laser abrasion with superficial full surface ablation, fractional laser treatment and conventional (deep) full surface CO2 laser…
- Trial name
- NCT02458417
- Testing
- ReCell, Full surface CO2 laser 200 mJ, Full surface CO2 laser 150 mJ
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- Netherlands Institute for Pigment Disorders
Dermatitis, Nevus
Assessment of Digital Imaging as a Tool for Diagnosing Psoriasis, Hand Rashes and Unusual Moles
This study will evaluate whether digital photography is a reliable tool for diagnosing hand rashes, psoriasis and unusual moles.
- Conditions
- Dermatitis, Nevus, Psoriasis
- Trial name
- NCT00005781
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- National Cancer Institute (NCI)
Breast Self-Examination, Breast Cancer
Experimental Study With Pretest/Posttest Groups Which the Intervention Group Have the System Which Sends Reminder Notifications Directing Them to the Website Containing BSE Training Along With the Illustrations Created for the Practice Prepared by the Researcher on the Determined Ideal Day
H0: Among the intervention and control groups of reminder notifications relating to self-examination H01: Average breast cancer fear score and H02: There is no difference in the average score of breast cancer health beliefs.
- Conditions
- Breast Self-Examination, Breast Cancer, Nursing Caries, Cancer
- Trial name
- BreastSelfExam (NCT05995483)
- Testing
- Early Diagnosis on BSE
- Where
- Cyprus
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University