Clinical trials: Skin Pigmentation
Acanthosis Nigricans
Systemic and Topical Metformin Versus Glycolic Acid Peel for the Treatment of Acanthosis Nigricans
Acanthosis nigricans (AN) is a common dermatologic condition associated with insulin resistance and obesity. Existing treatment options often provide inconsistent results.
- Trial name
- MET-AN (NCT07751549)
- Testing
- systemic metformin, topical intervention, glycolic acid 70% peeling
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Tanta University
Vitiligo Vulgaris
Questionnaire and Laboratory Data on Vitiligo Vulgaris
Vitiligo vulgaris is an autoimmune disorder that causes loss of pigmentation over the skin, hair and mucous membranes (e.g. lips, nose, genitals).
- Trial name
- NCT01206374
- Where
- 2 sites in United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Vitiligo
Afamelanotide and Narrow-Band Ultraviolet B (NB-UVB) Phototherapy in the Treatment of Nonsegmental Vitiligo (NSV)
The purpose of this study was to evaluate the efficacy and safety of afamelanotide, when combined with narrowband ultraviolet B (NB-UVB) phototherapy, in patients with nonsegmental vitiligo.
- Trial name
- NCT04525157
- Testing
- Afamelanotide
- Volunteers
- 21 people
- Sponsor
- Clinuvel Pharmaceuticals Limited
Post Inflammatory Hyperpigmentation
Tranexamic Acid vs Fractional CO2 Laser in Post-acne Hyperpigmentation
comparing between the effect of intradermal injection of TXA and low power low density fractional CO2 lasers on post acne hyperpigmentation
- Trial name
- NCT03765021
- Testing
- Tranexamic Acid, Fractional CO2 laser
- Volunteers
- 25 people
- Sponsor
- Cairo University
Vitiligo
Repigmentation of Stable Vitiligo Lesions Using Spray-On Skin™ Cells
To evaluate repigmentation and quality of life after treatment of stable vitiligo lesions using the RECELL Device.
- Trial name
- TONE (NCT05971381)
- Testing
- RECELL® Autologous Cell Harvesting Device
- Where
- 17 sites in United States
- Volunteers
- 109 people
- Sponsor
- Avita Medical
Vitiligo
UVA 1 Phototherapy for Vitiligo
Vitiligo is a chronic acquired disease characterized by well defined white macules and patches affecting the skin. There are many treatment modalities available for vitiligo, however, none of them cure the disease.
- Trial name
- NCT01787695
- Testing
- UVA1
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- University of British Columbia
Familial Pancreatic Cancer, BRCA1 Mutation
Registry of Subjects at Risk of Pancreatic Cancer
IRFARPC is a multicenter national registry designed to study the diagnosis and predisposing factors of subjects with an inherited increased risk for pancreatic cancer.
- Conditions
- Familial Pancreatic Cancer, BRCA1 Mutation, BRCA2 Mutation, Lynch Syndrome
- Trial name
- IRFARPC (NCT04095195)
- Testing
- MRCP, Endoultrasonography
- Where
- 4 sites in Italy
- Volunteers
- 1,000 people
- Sponsor
- Associazione Italiana per lo Studio del Pancreas
Mastocytosis
Mast Cell Connect: A Registry for Patients With Mastocytosis
The Mast Cell Connect Registry is a voluntary, observational database that will capture demographic, socioeconomic, and disease information directly from patients with mastocytosis via a secure web-based tool.
- Trial name
- NCT02620254
- Where
- United States
- Volunteers
- 743 people
- Sponsor
- Blueprint Medicines Corporation
Vitiligo, Psoriasis
Analysis of Inflammation in the Vitiligo and Other Inflammatory Skin Diseases: Psoriasis, Atopic Dermatitis and Alopecia Areata
It is a study of translational research with mechanistically objectives and including biological samples of patients with chronic inflammatory disorders
- Conditions
- Vitiligo, Psoriasis, Alopecia Areata, Atopic Dermatitis
- Trial name
- INFLAMMAVit (NCT03976622)
- Testing
- Blood samples, Skin biopsies
- Where
- France
- Volunteers
- 450 people
- Sponsor
- University Hospital, Bordeaux
VITILIGO
Epidermal Cell Transplantation in Vitiligo Skin
The effects of treatment of transplantation of harvested autologous epidermal cells on vitiligo lesions followed by narrow-band UVB will be investigated in a randomized controlled study.
- Trial name
- VITICELL (NCT01629979)
- Testing
- Grafting with epidermal cells, UVB treatment
- Where
- France
- Volunteers
- 23 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Healthy Participants
the Effect of Different Background Color and Skin Tone on the Accuracy of Auricular Scanning
The goal of this study is to find the best miss and match background color around an ear when taking scans for it , the investigators will recruit participants of three different skin tone and will scan their ear three times; one…
- Trial name
- NCT07108946
- Testing
- Black background, White background, Participant own skin as a background
- Where
- Egypt
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- yasmine Elsherbeeny
Hyperpigmentation
Fat Grafting an Ideal Filler For Contour Deformities With Hyperpigmentation On Face
Pigmentary changes are commonly associated with contour defects of facial region. These deformities cause cosmetic concerns. Traditionally used techniques indwelling limitations and therefore it invokes innovative techniques to…
- Trial name
- NCT06103461
- Testing
- Autologous fat grafting
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- King Edward Medical University
Skin Cancer, Malignant Melanoma
Fast Track Diagnosis of Skin Cancer by Advanced Imaging Technologies and Tumour Tapestripping
In this clinical feasibility study the investigators will test and compare two advanced optical imaging technologies, lipid and RNA tape stripping with regards to diagnostic accuracies for fast bedside diagnosis of pigmented skin…
- Trial name
- NCT05389085
- Testing
- Reflectance confocal microscopy (RCM), Photoacoustic imaging (PAI) and tape-strippng of RNA and lipids
- Where
- Denmark
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Laxity; Skin, Skin Hyperpigmentation
Comparison Of Aesthetic Techniques For Rejuvenation Of Genital Region: A Randomized Clinical Trial
The microneedle is a minimally invasive technique, consists of the application of a roller surrounded by small and thin needles that pierce the skin and generate a mechanical stimulus with no ablative effect on the skin.
- Conditions
- Laxity; Skin, Skin Hyperpigmentation, Needlestick Puncture
- Trial name
- NCT04998578
- Testing
- Comparison of aesthetic techniques
- Where
- 2 sites in Brazil
- Volunteers
- 112 people
- Sponsor
- Centro de Atenção ao Assoalho Pélvico